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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7340, pp. 597 - 601
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, pp. 28660 - 28660
We demonstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhibit ATP-dependent release of interleukin-1β from... 
Receptors, Nicotinic - metabolism | Animals | Interleukin-1beta - metabolism | Monocytes - cytology | U937 Cells | Humans | Receptors, Purinergic P2X7 - metabolism | Monocytes - metabolism | Mice | Phosphorylcholine - metabolism | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1312 - 1321
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2005, Volume 115, Issue 12, pp. 3634 - 3640
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2012, Volume 32, Issue 3, pp. 669 - 676
OBJECTIVE—Nicotinic acid (NA) treatment has been associated with benefits in atherosclerosis that are usually attributed to effects on plasma lipoproteins. The... 
atherosclerosis | macrophages | vascular biology | receptors | cholesterol-lowering drugs | LONG-TERM | INTEGRIN VLA-4 | ACTIVATION | DENDRITIC CELLS | KAPPA-B | FOAM CELLS | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXTENDED-RELEASE NIACIN | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Integrin alpha4beta1 - metabolism | Toll-Like Receptor 2 - agonists | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Human Umbilical Vein Endothelial Cells - immunology | Monocytes - metabolism | Monocytes - immunology | Niacin - pharmacology | Receptors, Prostaglandin - metabolism | Receptors, Immunologic - antagonists & inhibitors | Inflammation - metabolism | Transfection | Chemotaxis, Leukocyte - drug effects | I-kappa B Kinase - metabolism | RNA Interference | Inflammation Mediators - metabolism | Toll-Like Receptor 4 - agonists | Chemokine CCL2 - metabolism | Receptors, G-Protein-Coupled - drug effects | Interleukin-6 - metabolism | Receptors, Prostaglandin - antagonists & inhibitors | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Inflammation - immunology | Toll-Like Receptor 2 - metabolism | Cell Adhesion - drug effects | Toll-Like Receptor 4 - metabolism | Monocytes - drug effects | Transcription Factor RelA - metabolism | Lipopolysaccharides - pharmacology | Inflammation - genetics | Receptors, G-Protein-Coupled - genetics | Pyrazines - pharmacology | Vascular Cell Adhesion Molecule-1 - metabolism | Receptors, Nicotinic - genetics | Receptors, Immunologic - metabolism | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6734 - 6734
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 13, pp. 6076 - 6081
Spirolide and gymnodimine macrocyclic imine phycotoxins belong to an emerging class of chemical agents associated with marine algal blooms and shelfish... 
Receptors | Imines | Shellfish | Ligands | Agonists | Toxins | Pharmacology | Nicotinic receptors | Nitrogen | Oocytes | Pharmacological and structural analyses | Seafood poisoning | Acetylcholine binding protein | Nicotinic acetylcholine receptor | Marine phycotoxins | PLANKTON | acetylcholine binding protein | seafood poisoning | DINOFLAGELLATE ALEXANDRIUM-OSTENFELDII | SHELLFISH TOXINS | SPIROLIDE-C | PROTEIN | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | marine phycotoxins | AGONISTS | ACETYLCHOLINE-RECEPTOR | GYMNODIMINE | pharmacological and structural analyses | nicotinic acetylcholine receptor | REVEALS | Heterocyclic Compounds, 3-Ring - metabolism | Heterocyclic Compounds, 3-Ring - pharmacology | Nicotinic Antagonists - metabolism | Humans | Aplysia - metabolism | Crystallography, X-Ray | Acetylcholine - metabolism | Nicotinic Antagonists - pharmacology | Hydrocarbons, Cyclic - pharmacology | Imines - chemistry | Oocytes - drug effects | Carrier Proteins - chemistry | Female | Molecular Structure | Spiro Compounds - chemistry | Receptors, Nicotinic - metabolism | Marine Toxins - metabolism | Oocytes - metabolism | Imines - metabolism | Models, Molecular | Electric Organ - metabolism | Marine Toxins - pharmacology | Imines - pharmacology | Macromolecular Substances | Animals | Carrier Proteins - metabolism | Xenopus - metabolism | Marine Toxins - chemistry | Nicotinic Antagonists - chemistry | Heterocyclic Compounds, 3-Ring - chemistry | Torpedo - metabolism | Kinetics | In Vitro Techniques | Hydrocarbons, Cyclic - chemistry | Spiro Compounds - pharmacology | Hydrocarbons, Cyclic - metabolism | Spiro Compounds - metabolism | Marine toxins | Crystals | Physiological aspects | Acetylcholine | Structure | Properties | Protein binding | Proteins | Neurons | Chemical compounds | Binding sites | Crystal structure | Index Medicus | Life Sciences | Neurons and Cognition | Biological Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2014, Volume 289, Issue 31, pp. 21795 - 21806
The α4β2 nicotinic acetylcholine receptor (nAChR) is the most abundant nAChR type in the brain, and this receptor type exists in alternate (α4β2)2α4 and... 
Ligands | Receptors, Nicotinic - metabolism | Animals | Receptors, Nicotinic - genetics | Xenopus laevis | Nicotinic Agonists - pharmacology | Index Medicus | Nicotinic Acetylcholine Receptor (nAChR) | Electrophysiology | Ligand-binding Protein | Receptor Structure-Function | Cys-loop Receptor | Neurobiology
Journal Article