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1. The nicotinic acetylcholine receptor
: current views and future trends
by Barrantes, Francisco Jose, 1944
1998, Biotechnology intelligence unit, ISBN 3540642587, 226
physiology | Receptors | Acetylcholine | Receptors, Nicotinic | Nicotinic receptors | Receptors, Cholinergic
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2. Full Text Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice
by Hanson, Julien and Gille, Aneas and Zwykiel, Sabrina and Lukasova, Martina and Clausen, Björn E and Ahmed, Kashan and Tunaru, Sorin and Wirth, Angela and Offermanns, Stefan
Journal of clinical investigation, ISSN 0021-9738, 2010, Volume 120, Issue 8, pp. 2910 - 2919
The antidyslipidemic drug nicotinic acid and the antipsoriatic drug monomethyl fumarate induce cutaneous flushing through activation of G protein-coupled... 
MEDICINE, RESEARCH & EXPERIMENTAL | IN-VITRO | ACTIVATION | PUMA-G | RECEPTOR | CYCLOOXYGENASE | PROSTAGLANDIN D-2 | MOUSE SKIN | LANGERHANS CELLS | NIACIN | LAROPIPRANT | Dinoprostone - biosynthesis | Humans | Mice, Inbred C57BL | Cells, Cultured | Cyclooxygenase 1 - physiology | Cyclooxygenase 2 - physiology | Fumarates - toxicity | Animals | Receptors, Nicotinic - physiology | Keratinocytes - metabolism | Mice | Receptors, G-Protein-Coupled - genetics | Flushing - chemically induced | Langerhans Cells - metabolism | Niacin - toxicity | Receptors, Nicotinic - genetics | Receptors, G-Protein-Coupled - physiology | Complications and side effects | Physiological aspects | Keratinocytes | Genetic aspects | Gene expression | Properties | Niacin | Prostanoids | Index Medicus | Abridged Index Medicus
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3. Full Text Prolonged disynaptic inhibition in the cortex mediated by slow, non-α7 nicotinic excitation of a specific subset of cortical interneurons
by Arroyo, Sergio and Bennett, Corbett and Aziz, David and Brown, Solange P and Hestrin, Shaul
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 11, pp. 3859 - 3864
Cholinergic activation of nicotinic receptors in the cortex plays a critical role in arousal, attention, and learning. Here we demonstrate that cholinergic... 
Interneurons - physiology | Action Potentials - genetics | Synapses - physiology | Male | Mice, Transgenic | Axons - physiology | Synapses - genetics | Reaction Time - genetics | Cerebral Cortex - cytology | Cholinergic Neurons - physiology | Action Potentials - physiology | Neural Inhibition - physiology | Animals | Receptors, Nicotinic - physiology | Time Factors | Cerebral Cortex - physiology | Female | Interneurons - classification | Mice | alpha7 Nicotinic Acetylcholine Receptor | Index Medicus
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4. Full Text Delayed procedural learning in α7‐nicotinic acetylcholine receptor knockout mice
by Young, J. W and Meves, J. M and Tarantino, I. S and Caldwell, S and Geyer, M. A
Genes, Brain and Behavior, ISSN 1601-1848, 10/2011, Volume 10, Issue 7, pp. 720 - 733
The α 7‐nicotinic acetylcholine receptor (nAChR) has long been a procognitive therapeutic target to treat schizophrenia. Evidence on the role of this receptor... 
exploration | 7‐nicotinic acetylcholine receptor | motivation | procedural learning | short‐term memory | prepulse inhibition | schizophrenia | set‐shifting | mutant | mice | Motivation | Mutant | Short-term memory | Schizophrenia | α7-nicotinic acetylcholine receptor | Exploration | Mice | Set-shifting | Procedural learning | Prepulse inhibition | Maze Learning - physiology | Mice, Inbred C57BL | Sensory Gating - physiology | Memory, Short-Term - physiology | Executive Function - physiology | Recognition (Psychology) - physiology | Mice, Knockout | Attention - physiology | Exploratory Behavior - physiology | Animals | Motivation - physiology | Receptors, Nicotinic - physiology | Pattern Recognition, Physiological - physiology | Cognition - physiology | Receptors, Nicotinic - genetics | alpha7 Nicotinic Acetylcholine Receptor | Index Medicus | short-term memory | set-shifting
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5. Full Text Photoactivatable drugs for nicotinic optopharmacology
by Banala, Sambashiva and Arvin, Matthew C and Bannon, Nicholas M and Jin, Xiao-Tao and Macklin, John J and Wang, Yong and Peng, Can and Zhao, Guiqing and Marshall, John J and Gee, Kyle R and Wokosin, David L and Kim, Veronica J and McIntosh, J. Michael and Contractor, Anis and Lester, Henry A and Kozorovitskiy, Yevgenia and Drenan, Ryan M and Lavis, Luke D
Nature Methods, ISSN 1548-7091, 04/2018, Volume 15, Issue 5, pp. 347 - 350
Photoactivatable pharmacological agents have revolutionized neuroscience, but the palette of available compounds is limited. We describe a general method for... 
ACETYLCHOLINE-RECEPTORS | CROSS-SECTIONS | FLUOROPHORES | AMINES | ALPHA-CONOTOXIN | BIOCHEMICAL RESEARCH METHODS | NEURONS | PHOTORELEASE | RELEASE | CELL | EXPRESSION | Brain - drug effects | Brain - metabolism | Immunohistochemistry | Microscopy, Confocal | Animals | Calcium | Receptors, Nicotinic - physiology | Spectrometry, Fluorescence | Mice | Spectrophotometry, Ultraviolet | Nicotine - pharmacology | Photochemical Processes | Research | Neurophysiology | Receptors | Ammonium | Red shift | Amines | Quaternary | Acetylcholine receptors (nicotinic) | Nervous system | Pharmacology | Acetylcholine | Doppler effect | Nicotine | Index Medicus
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6. Full Text Gating of Long-Term Potentiation by Nicotinic Acetylcholine Receptors at the Cerebellum Input Stage
by Prestori, Francesca and Bonardi, Claudia and Mapelli, Lisa and Lombardo, Paola and Goselink, Rianne and Stefano, Maria Egle and Gandolfi, Daniela and Mapelli, Jonathan and Bertrand, Daniel and Schonewille, Martijn and Zeeuw, Chris and D'Angelo, Egidio
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e64828 - e64828
textabstractThe brain needs mechanisms able to correlate plastic changes with local circuit activity and internal functional states. At the cerebellum input... 
HIPPOCAMPAL SYNAPTIC PLASTICITY | TACTILE STIMULATION | RAT CEREBELLUM | ACH RECEPTORS | NMDA RECEPTORS | NEUROTRANSMITTER RELEASE | MULTIDISCIPLINARY SCIENCES | GRANULE CELL SYNAPSES | DIFFERENTIALLY FACILITATE | SPATIAL-ORGANIZATION | DENTATE GYRUS | Reflex, Vestibulo-Ocular - physiology | Synaptic Transmission - physiology | Synapses - physiology | Rats | Nerve Fibers - drug effects | Cerebellum - physiology | Animals | Nerve Fibers - physiology | Long-Term Potentiation - drug effects | Receptors, Nicotinic - physiology | Reflex, Vestibulo-Ocular - drug effects | alpha7 Nicotinic Acetylcholine Receptor - physiology | Long-Term Potentiation - physiology | Synaptic Transmission - drug effects | Mice | Nicotinic Agonists - pharmacology | Brain | Cerebellum | Potentiation | Neurosciences | Calcium | Synaptic strength | Memory | Activation | Neuromodulation | Fibers | Learning | Receptors | Plasticity | Physiology | Dendrites | Trends | Gating | Adaptation | Channel gating | Granule cells | Long-term potentiation | Pharmacology | Plasticity (cerebellar) | Neurology | Granular materials | Sensory stimulation | Acetylcholine receptors (nicotinic) | Plastic properties | Acetylcholine | Mossy fibers | Nicotine | Index Medicus | Receptors, Nicotinic | Neurons and Cognition | Synaptic Transmission | Life Sciences | Nicotinic Agonists | Long-Term Potentiation | Nerve Fibers | Synapses | Reflex, Vestibulo-Ocular | alpha7 Nicotinic Acetylcholine Receptor
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7. Full Text Neural Signatures of Cognitive Flexibility and Reward Sensitivity Following Nicotinic Receptor Stimulation in Dependent Smokers: A Randomized Trial
by Lesage, Elise and Aronson, Sarah E and Sutherland, Matthew T and Ross, Thomas J and Salmeron, Betty Jo and Stein, Elliot A
JAMA Psychiatry, ISSN 2168-622X, 06/2017, Volume 74, Issue 6, pp. 632 - 640
IMPORTANCE: Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence... 
VENTROMEDIAL PREFRONTAL CORTEX | DECISION-MAKING | RESPONSE PERSEVERATION | PSYCHIATRY | ANTERIOR CINGULATE | DRUG-ADDICTION | FUNCTIONAL CONNECTIVITY | MONETARY REWARD | ABSTINENT CIGARETTE SMOKERS | BRAIN ACTIVATION | SMOKING ABSTINENCE | Reversal Learning - drug effects | Reversal Learning - physiology | Humans | Male | Cerebral Cortex - physiopathology | Nicotine - adverse effects | Motivation - drug effects | Limbic System - physiopathology | Tobacco Use Disorder - psychology | Adult | Female | Cerebral Cortex - drug effects | Varenicline - therapeutic use | Impulsive Behavior - physiology | Limbic System - drug effects | Receptors, Nicotinic - drug effects | Double-Blind Method | Tobacco Use Cessation Devices | Impulsive Behavior - drug effects | Tobacco Use Disorder - physiopathology | Executive Function - physiology | Cross-Over Studies | Motivation - physiology | Receptors, Nicotinic - physiology | Reward | Substance Withdrawal Syndrome - physiopathology | Substance Withdrawal Syndrome - psychology | Smoking Cessation - psychology | Executive Function - drug effects | Usage | Smokers | Magnetic resonance imaging | Nicotinic receptors | Health aspects | Smoking cessation products | Index Medicus | Abridged Index Medicus | Online First | Original Investigation | Research
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8. Full Text Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors
by Tochitsky, Ivan and Banghart, Matthew R and Mourot, Alexandre and Yao, Jennifer Z and Gaub, Benjamin and Kramer, Richard H and Trauner, Dirk
Nature Chemistry, ISSN 1755-4330, 02/2012, Volume 4, Issue 2, pp. 105 - 111
Advances in synthetic chemistry, structural biology, molecular modelling and molecular cloning have enabled the systematic functional manipulation of... 
ACTIVATION | DOMAIN | ALPHA-SUBUNIT | LIGANDS | REMOTE-CONTROL | DOCKING | BINDING-SITE | BOUND AGONISTS | MECHANISMS | ION CHANNELS | CHEMISTRY, MULTIDISCIPLINARY | Animals | Genetic Engineering | Receptors, Nicotinic - chemistry | Receptors, Nicotinic - physiology | Models, Molecular | Rats | Receptors, Nicotinic - genetics | Photochemistry | Index Medicus | Life Sciences | Neurons and Cognition
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9. Full Text RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
by Wallace, Tanya L and Callahan, Patrick M and Tehim, Ashok and Bertrand, Daniel and Tombaugh, Geoffrey and Wang, Shaojie and Xie, Walter and Rowe, Wayne B and Ong, Voon and Graham, Elizabeth and Terry Jr, Alvin V and Rodefer, Joshua S and Herbert, Brian and Murray, Michael and Porter, Richard and Santarelli, Luca and Lowe, David A
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 01/2011, Volume 336, Issue 1, pp. 243 - 253
Neuronal nicotinic α7 acetylcholine receptors (α7nAChRs) are expressed primarily in the brain and are implicated in modulating many cognitive functions (e.g.,... 
Sensory Gating - drug effects | Binding, Competitive - physiology | Drug Partial Agonism | Bridged Bicyclo Compounds - pharmacology | Rats, Wistar | Humans | Rats, Inbred F344 | Rats, Long-Evans | Xenopus laevis | Rats | Male | Sensory Gating - physiology | Cognition - drug effects | Rats, Sprague-Dawley | Binding, Competitive - drug effects | Indazoles - pharmacology | Animals | Receptors, Nicotinic - physiology | Cell Line, Tumor | Cognition - physiology | Female | Nicotinic Agonists - pharmacology | alpha7 Nicotinic Acetylcholine Receptor | Index Medicus
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10. Full Text Subunit Composition of Functional Nicotinic Receptors in Dopaminergic Neurons Investigated with Knock-Out Mice
by Champtiaux, Nicolas and Gotti, Cecilia and Cordero-Erausquin, Matilde and David, Denis J and Przybylski, Cedric and Lena, Clement and Clementi, Francesco and Moretti, Milena and Rossi, Francesco M and Le Novere, Nicolas and McIntosh, J. Michael and Gardier, Alain M and Changeux, Jean-Pierre
Journal of Neuroscience, ISSN 0270-6474, 08/2003, Volume 23, Issue 21, pp. 7820 - 7829
Nicotinic acetylcholine receptors (nAChRs) expressed by dopaminergic (DA) neurons have long been considered as potential therapeutic targets for the treatment... 
Striatum | α-conotoxine MII | Dopamine | Mesencephalon | Knock-out mice | Nicotinic acetylcholine receptors | DOPAMINE RELEASE | mesencephalon | SUBTYPES | RAT STRIATAL SYNAPTOSOMES | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | BETA 2 | ACETYLCHOLINE-RECEPTORS | striatum | MESSENGER-RNA | alpha-conotoxine MII | ALPHA-CONOTOXIN-MII | knock-out mice | nicotinic acetylcholine receptors | dopamine | BRAIN | Protein Subunits | Synaptosomes - drug effects | Neostriatum - chemistry | Nicotinic Agonists - metabolism | Nicotinic Antagonists - metabolism | Nucleus Accumbens - metabolism | Electric Conductivity | Ventral Tegmental Area - cytology | Synaptosomes - metabolism | Ventral Tegmental Area - physiology | Substantia Nigra - cytology | Nicotine - pharmacology | Receptors, Nicotinic - analysis | Neurons - physiology | Neostriatum - metabolism | Mesencephalon - physiology | Neurons - drug effects | Dopamine - metabolism | Receptors, Nicotinic - metabolism | Acetylcholine - pharmacology | Cells, Cultured | Mice, Knockout | Receptors, Nicotinic - immunology | Patch-Clamp Techniques | Animals | Receptors, Nicotinic - physiology | Mice | Receptors, Nicotinic - genetics | Substantia Nigra - physiology | Index Medicus
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11. Full Text Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity
by Gu, Zhenglin and Yakel, Jerrel L
Neuron, ISSN 0896-6273, 2011, Volume 71, Issue 1, pp. 155 - 165
Cholinergic modulation of hippocampal synaptic plasticity has been studied extensively by applying receptor agonists or blockers; however, the effect of rapid... 
ACETYLCHOLINE-RECEPTORS | ALPHA-7-CONTAINING NICOTINIC RECEPTORS | INHIBITION | MEMORY | PYRAMIDAL CELLS | ALZHEIMERS-DISEASE | AMYLOID-BETA-PEPTIDE | CENTRAL-NERVOUS-SYSTEM | SK CHANNELS | LONG-TERM POTENTIATION | NEUROSCIENCES | Cholinergic Fibers - physiology | Synaptic Transmission - physiology | Rats, Wistar | Amyloid beta-Peptides - pharmacology | Septum of Brain - physiology | Neuronal Plasticity - drug effects | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Neural Inhibition - physiology | Neuronal Plasticity - physiology | Choline O-Acetyltransferase - physiology | Time Factors | Synaptic Transmission - drug effects | Electric Stimulation - methods | Cholinergic Fibers - drug effects | Choline O-Acetyltransferase - genetics | Rats | Mice, Transgenic | Septum of Brain - drug effects | Mice, Knockout | Animals | Photic Stimulation - methods | Receptors, Nicotinic - physiology | Mice | Hippocampus - physiology | Neural Inhibition - drug effects | Receptors, Nicotinic - genetics | Receptors, Muscarinic - physiology | alpha7 Nicotinic Acetylcholine Receptor | Neurons | Memory | Light | Rodents | Animal cognition | Index Medicus | Acetylcholine receptors (muscarinic)
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12. Full Text Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula
by Shih, Pei-Yu and Engle, Staci E and Oh, Gyeon and Deshpande, Purnima and Puskar, Nyssa L and Lester, Henry A and Drenan, Ryan M
Journal of Neuroscience, ISSN 0270-6474, 2014, Volume 34, Issue 29, pp. 9789 - 9802
Neuronal nAChRs in the medial habenula (MHb) to the interpeduncular nucleus (IPN) pathway are key mediators of nicotine's aversive properties. In this paper,... 
Nicotinic | Tobacco | Withdrawal | Interpeduncular | Habenula | Nicotine | nicotine | ACTIVATION | nicotinic | INTERPEDUNCULAR NUCLEUS | withdrawal | habenula | NEUROSCIENCES | DOPAMINE NEURONS | SUBUNIT MESSENGER-RNAS | interpeduncular | tobacco | RAT-BRAIN | UP-REGULATION | MIDBRAIN | GABAERGIC NEURONS | ALPHA-4-BETA-2 | Membrane Potentials - genetics | Electric Stimulation | Gene Expression - drug effects | Gene Expression - genetics | Male | Green Fluorescent Proteins - genetics | Choline O-Acetyltransferase - metabolism | Protein Subunits - metabolism | Nicotine - pharmacology | Dose-Response Relationship, Drug | Habenula - drug effects | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Neurons - metabolism | Neurons - drug effects | Protein Subunits - genetics | Membrane Potentials - drug effects | Habenula - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Membrane Potentials - physiology | Patch-Clamp Techniques | Animals | Habenula - cytology | Receptors, Nicotinic - physiology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Mice | In Vitro Techniques | Receptors, Nicotinic - genetics | Index Medicus
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13. Full Text Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors
by Mameli-Engvall, Monica and Evrard, Alexis and Pons, Stéphanie and Maskos, Uwe and Svensson, Torgny H and Changeux, Jean-Pierre and Faure, Philippe
Neuron, ISSN 0896-6273, 2006, Volume 50, Issue 6, pp. 911 - 921
Nicotine elicits dopamine release by stimulating nicotinic acetylcholine receptors (nAChRs) on dopaminergic neurons. However, a modulation of these neurons by... 
SYSNEURO | MOLNEURO | SIGNALING | MEDIAL FOREBRAIN-BUNDLE | ACETYLCHOLINE-RECEPTORS | RAT | AFFERENT MODULATION | PUTATIVE ROLE | ELECTROPHYSIOLOGICAL PROPERTIES | SYNAPTIC MECHANISMS | NEUROSCIENCES | BURST STIMULATION | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | Action Potentials - genetics | Mice, Inbred C57BL | Male | Mice, Knockout | Nicotine - pharmacology | Action Potentials - physiology | Animals | Receptors, Nicotinic - physiology | Dopamine - physiology | Neurons - physiology | Receptors, Nicotinic - deficiency | Mice | Neurons - drug effects | Receptors, Nicotinic - genetics | Action Potentials - drug effects | alpha7 Nicotinic Acetylcholine Receptor | Physiological aspects | Phenols | Dopamine | Neurons | Analysis | Nicotine | Rodents | Index Medicus | Action Potentials | Life Sciences | Microbiology and Parasitology | Receptors, Nicotinic
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