X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (21308) 21308
Book Chapter (28) 28
Book / eBook (12) 12
Conference Proceeding (9) 9
Dissertation (8) 8
Newspaper Article (5) 5
Publication (3) 3
Web Resource (2) 2
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (14847) 14847
humans (11946) 11946
mice (7305) 7305
signal transduction (7067) 7067
cell biology (5387) 5387
receptors, notch - metabolism (4949) 4949
expression (4637) 4637
female (4358) 4358
male (3657) 3657
gene expression (3567) 3567
biochemistry & molecular biology (3229) 3229
notch (3154) 3154
proteins (3123) 3123
oncology (3035) 3035
differentiation (3001) 3001
research (2938) 2938
cancer (2884) 2884
stem cells (2727) 2727
developmental biology (2669) 2669
activation (2667) 2667
cell differentiation (2580) 2580
membrane proteins - metabolism (2580) 2580
cell proliferation (2455) 2455
multidisciplinary sciences (2342) 2342
research article (2313) 2313
cell line, tumor (2274) 2274
cells, cultured (2240) 2240
apoptosis (2155) 2155
analysis (2066) 2066
genetic aspects (2008) 2008
neurosciences (1981) 1981
signal transduction - physiology (1968) 1968
physiological aspects (1954) 1954
mutation (1951) 1951
receptors, notch - genetics (1910) 1910
receptor, notch1 - metabolism (1853) 1853
biology (1835) 1835
mice, inbred c57bl (1817) 1817
gene-expression (1780) 1780
immunology (1780) 1780
medicine (1775) 1775
receptor (1765) 1765
ligands (1702) 1702
gene expression regulation, developmental (1631) 1631
cells (1619) 1619
genes (1594) 1594
kinases (1585) 1585
rodents (1582) 1582
transcription factors (1568) 1568
membrane proteins - genetics (1537) 1537
drosophila (1528) 1528
signal transduction - drug effects (1492) 1492
mice, knockout (1491) 1491
tumors (1477) 1477
cell line (1405) 1405
rats (1392) 1392
science (1385) 1385
receptors, notch (1378) 1378
stem-cells (1366) 1366
growth (1356) 1356
proliferation (1343) 1343
gene (1342) 1342
pathway (1338) 1338
angiogenesis (1324) 1324
health aspects (1309) 1309
genetics & heredity (1289) 1289
medicine, research & experimental (1269) 1269
in-vivo (1259) 1259
mice, transgenic (1257) 1257
signaling (1232) 1232
immunohistochemistry (1212) 1212
models, biological (1201) 1201
signal transduction - genetics (1185) 1185
receptor, notch1 - genetics (1182) 1182
phenotype (1179) 1179
transcription factors - metabolism (1178) 1178
gene expression regulation (1175) 1175
receptors (1146) 1146
protein (1130) 1130
phosphorylation (1105) 1105
inflammation (1081) 1081
gene expression regulation, neoplastic (1079) 1079
metastasis (1079) 1079
drosophila proteins - metabolism (1067) 1067
adult (1047) 1047
disease models, animal (1044) 1044
progenitor cells (1043) 1043
genetics (1027) 1027
middle aged (1024) 1024
neurons (1010) 1010
in-vitro (1006) 1006
inhibition (1004) 1004
hematology (989) 989
gene expression profiling (986) 986
protein binding (968) 968
down-regulation (966) 966
review (953) 953
breast cancer (952) 952
transcription (936) 936
development and progression (932) 932
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (21315) 21315
Chinese (94) 94
Japanese (68) 68
French (7) 7
Russian (6) 6
Hungarian (3) 3
Polish (3) 3
German (2) 2
Spanish (2) 2
Amharic (1) 1
Czech (1) 1
Dutch (1) 1
Korean (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


2018, Advances in Experimental Medicine and Biology, ISBN 3319895117, Volume 1066, 417
This book describes the Notch signaling pathway with a focus on molecular mechanisms. 
Cellular signal transduction | Life Sciences | Receptors | Protein Structure | Protein-Ligand Interactions
eBook
2012, 1. Aufl., Advances in experimental medicine and biology, ISBN 1461408989, Volume 727., xxi, 328
"The goal of this volume is to comprehensively cover a highly readable overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology... 
Cellular signal transduction | Embryology | Notch proteins | Cancer | Embryology, Human
Book
Stem cells (Dayton, Ohio), ISSN 1549-4918, 2009, Volume 28, Issue 1, pp. 17 - N/A
.... The Notch pathway is critically implicated in stem cell fate determination and cancer. In this study, we show that inhibition of Notch pathway with γ... 
Radioresistance | Glioma | Cancer stem cells | Radioresponse | Notch | APOPTOSIS | GAMMA-SECRETASE INHIBITOR | DNA-DAMAGE | MOUSE MODELS | TUMOR-INITIATING CELLS | BRAIN-TUMORS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | BREAST-CANCER | GROWTH-FACTOR RECEPTOR | ONCOLOGY | HUMAN GLIOBLASTOMA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IONIZING-RADIATION | HEMATOLOGY | Cell Proliferation | Neoplastic Stem Cells - drug effects | Humans | Glycoproteins - metabolism | Receptor, Notch2 - genetics | Phosphatidylinositol 3-Kinases - metabolism | Glioblastoma - radiotherapy | Antigens, CD - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Peptides - metabolism | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Cell Death | Neoplastic Stem Cells - pathology | Glioblastoma - metabolism | Signal Transduction - radiation effects | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Spheroids, Cellular | Neoplastic Stem Cells - radiation effects | Cell Survival | Radiation-Sensitizing Agents - pharmacology | Enzyme Inhibitors - pharmacology | Receptor, Notch2 - metabolism | Receptor, Notch1 - metabolism | Tumor Burden | AC133 Antigen | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Amyloid Precursor Protein Secretases - metabolism | Animals | Mice, Nude | Glioblastoma - pathology | Myeloid Cell Leukemia Sequence 1 Protein | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Glioblastoma - drug therapy | Receptor, Notch1 - genetics | Dose-Response Relationship, Radiation
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 2016, Volume 127, Issue 1, pp. 137 - 152
Journal Article
Nature cell biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 278 - 285
The Notch signalling pathway has a crucial function in determining cell fates in multiple tissues within metazoan organisms(1... 
COACTIVATOR | PROTEIN | DROSOPHILA MASTERMIND | PHOSPHORYLATION | PATHWAY | HOMOLOG | DIFFERENTIATION | NLK | RECEPTORS | EXPRESSION | CELL BIOLOGY | Phosphorylation - physiology | Xenopus | RNA, Small Interfering - genetics | ELAV-Like Protein 3 | Transcription Factor HES-1 | Protein Interaction Domains and Motifs - physiology | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Humans | Embryo, Nonmammalian - metabolism | Receptors, Notch - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nuclear Proteins - genetics | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Zebrafish Proteins - metabolism | ELAV Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Gene Expression Regulation - physiology | Nuclear Proteins - metabolism | Zebrafish | DNA - metabolism | Receptor, Notch1 - metabolism | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Oligonucleotides, Antisense - genetics | Amino Acid Substitution - physiology | Models, Biological | Neurogenesis - physiology | Cell Line, Tumor | Mitogen-Activated Protein Kinases - genetics | Signal Transduction - physiology | Mice | Zebrafish Proteins - genetics | Receptor, Notch1 - genetics | Mitogen-Activated Protein Kinases - metabolism | Protein Binding - physiology | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Genetic transcription | Protein kinases
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2011, Volume 121, Issue 4, pp. 1373 - 1385
Journal Article
Nature cell biology, ISSN 1476-4679, 2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2015, Volume 125, Issue 4, pp. 1579 - 1590
...) to nuclear and mitochondria! genes that encode respiratory chain components and by NOTCH-dependent induction of pyruvate dehydrogenase phosphatase 1 (Pdp1... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE | ALCOHOL | INFLAMMATION | TRANSCRIPTION | ROS | NITRIC-OXIDE | RECEPTOR | HYPOXIA | FATE | POLARIZATION | Up-Regulation | Macrophage Activation - genetics | Reactive Oxygen Species - metabolism | Electron Transport - genetics | Liver Failure, Acute - etiology | Male | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - antagonists & inhibitors | Fatty Liver, Alcoholic - metabolism | Inflammation - metabolism | Receptor, Notch1 - deficiency | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - metabolism | Transcription, Genetic | Fatty Liver, Alcoholic - pathology | Macrophage Activation - physiology | Protein Structure, Tertiary | Pyruvate Dehydrogenase Complex - metabolism | Cell Line | Mice, Inbred C57BL | Gene Expression Regulation | Oxidative Phosphorylation | Fatty Liver, Alcoholic - immunology | Inflammation - immunology | Liver Failure, Acute - metabolism | Mitochondria - metabolism | Mice, Knockout | Feedback, Physiological | Animals | Endotoxemia - complications | Liver Failure, Acute - immunology | Liver Failure, Acute - pathology | Glucose - metabolism | Myeloid Cells - metabolism | Signal Transduction - physiology | Mice | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - genetics | Myeloid Cells - pathology | Nitric Oxide - metabolism | Receptor, Notch1 - physiology | Cell metabolism | Genetic research | Genetic aspects | Genetic transcription | Research | Macrophages | Properties | Liver diseases | Cytokines | Microscopy | Pilot projects | Rodents | Mitochondrial DNA | Metabolism | Gene expression | Hepatology | Inflammation | Immunology
Journal Article
Cell Stem Cell, ISSN 1934-5909, 07/2014, Volume 15, Issue 1, pp. 51 - 65
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2011, Volume 208, Issue 10, pp. 1931 - 1935
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2014, Volume 211, Issue 11, pp. 2265 - 2279
Journal Article