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Journal Article
Journal Article
Immunity, ISSN 1074-7613, 06/2015, Volume 42, Issue 6, pp. 1159 - 1170
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6165 - 6177
Purpose: Antibodies specific for inhibitory checkpoints PD-1 and CTLA-4 have shown impressive results against solid tumors. This has fueled interest in novel... 
ONCOLOGY | THERAPEUTIC-EFFICACY | IMMUNE-RESPONSES | POOR-PROGNOSIS | CD4(+) T-CELLS | COSTIMULATORY MOLECULE | ESTABLISHED MELANOMA | OVARIAN-CANCER | HUMAN BREAST-CANCER | LYMPHOPENIC HOSTS | ANTITUMOR EFFICACY | T-Lymphocyte Subsets - immunology | Immunotherapy - methods | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Receptors, OX40 - metabolism | Time Factors | T-Lymphocyte Subsets - drug effects | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Molecular Targeted Therapy - methods | Cytokines - blood | Disease Models, Animal | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Mice, Transgenic | Survival Rate | Treatment Outcome | Lymphocytes, Tumor-Infiltrating - drug effects | Antineoplastic Agents, Immunological - pharmacology | Xenograft Model Antitumor Assays | Animals | Antineoplastic Agents, Immunological - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | T-Lymphocyte Subsets - metabolism | Lymphocyte Count | Mice | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, OX40 - antagonists & inhibitors | Cell proliferation | Animal models | PD-1 protein | CD8 antigen | Clinical trials | Antibodies | Lymphocytes T | Contraction | Anticancer properties | Receptors | CTLA-4 protein | Cell activation | Cell growth | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Immunotherapy | Medical research | Cytokines | T cell receptors | CD4 antigen | Immune checkpoint | Experimental design | Tumor necrosis factor | Exhaustion | Antitumor activity | Solid tumors | Tumors | Cancer | Combination immunotherapy | T cells | Costimulation | Checkpoint blockade
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 9, pp. 1743 - 1759
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2017, Volume 199, Issue 4, pp. 1238 - 1249
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2010, Volume 207, Issue 4, pp. 699 - 709
The immune response in the gastrointestinal tract is a tightly controlled balance between effector and regulatory cell responses. Here, we have investigated... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | GITR | INFLAMMATORY-BOWEL-DISEASE | DENDRITIC CELLS | SCID MICE | FAMILY-MEMBERS | IN-VIVO | EXPANSION | ANTIGEN-PRESENTING CELLS | IMMUNOLOGY | EXPRESSION | T-Lymphocyte Subsets - immunology | Tumor Necrosis Factors - genetics | T-Lymphocytes, Regulatory - metabolism | Receptors, OX40 - genetics | Cell Proliferation | T-Lymphocyte Subsets - cytology | Gene Expression - genetics | Cell Count | Colitis - pathology | Colon - immunology | Interferon-gamma - metabolism | Integrins - metabolism | Lymphoid Tissue - immunology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Intestinal Mucosa - cytology | Lymphocyte Activation - immunology | Receptors, OX40 - metabolism | Forkhead Transcription Factors - metabolism | Intestinal Mucosa - immunology | Gene Expression - immunology | Colitis - immunology | Disease Models, Animal | Colon - pathology | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Forkhead Transcription Factors - genetics | T-Lymphocyte Subsets - transplantation | Colon - metabolism | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Interleukin-17 - metabolism | Lymphoid Tissue - cytology | Animals | Apoptosis - immunology | CD4-Positive T-Lymphocytes - transplantation | T-Lymphocyte Subsets - metabolism | Colitis - metabolism | Leukocyte Common Antigens - genetics | Mice | T-Lymphocytes, Regulatory - transplantation | Brief Definitive Report
Journal Article
Immunity, ISSN 1074-7613, 04/2013, Volume 38, Issue 4, pp. 655 - 668
Journal Article