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Pharmacological Reviews, ISSN 0031-6997, Volume 65, Issue 1, pp. 223 - 254
Morphine and related µ-opioid receptor (MOR) agonists remain among the most effective drugs known for acute relief of severe pain. A major problem in treating... 
Phosphorylation | Receptors, Opioid, mu - chemistry | Animals | Humans | Drug Tolerance | Analgesics, Opioid - pharmacology | Phosphoric Monoester Hydrolases - metabolism | Receptors, Opioid, mu - physiology | Review
Journal Article
Pharmacological Reviews, ISSN 0031-6997, 12/2011, Volume 63, Issue 4, pp. 1001 - 1019
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3387 - 3391
Addictive diseases, including addiction to heroin, prescription opioids, or cocaine, pose massive personal and public health costs. Addictions are chronic... 
STEADY-STATE METHADONE | FREELY MOVING RATS | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VIVO MICRODIALYSIS | CORTICOTROPIN-RELEASING-FACTOR | MU-OPIOID-RECEPTOR | CHRONIC BINGE COCAINE | HPA-AXIS ACTIVATION | SINGLE-NUCLEOTIDE POLYMORPHISM | METHADONE-MAINTENANCE TREATMENT | MESSENGER-RNA LEVELS | Opioid-Related Disorders - drug therapy | Humans | Methadone - therapeutic use | Stress, Physiological | Cocaine-Related Disorders - genetics | Cocaine-Related Disorders - physiopathology | Neuropeptides - physiology | Receptors, Dopamine - drug effects | Receptors, Opioid - physiology | Dopamine - physiology | Opioid-Related Disorders - genetics | Dopaminergic Neurons - physiology | Limbic System - physiopathology | Hypothalamo-Hypophyseal System - physiopathology | Receptors, Dopamine - physiology | Limbic System - drug effects | Genetic Predisposition to Disease | Pharmacogenetics | Pituitary-Adrenal System - physiopathology | Basal Ganglia - physiopathology | Receptors, Opioid, mu - drug effects | Rats | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Cocaine-Related Disorders - drug therapy | Mice | Opioid-Related Disorders - physiopathology | Receptors, Opioid, mu - genetics | Reward | Receptors, Dopamine - genetics | Receptors, Opioid - drug effects | Basal Ganglia - drug effects | Receptors, Opioid, mu - physiology | Stress, Psychological - physiopathology | Messenger RNA | Opioids | Physiological aspects | Cocaine | Research | Health aspects | Sensory adaptation | Science in Medicine
Journal Article