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2016, Current Topics in Neurotoxicity, ISBN 3319351354, Volume 11
The first comprehensive book to cover all aspects of the last 25 years of PACAP (pituitary adenylate cyclase activating polypeptide) research, this book... 
Medicine | Neurosciences
Web Resource
Molecular Psychiatry, ISSN 1359-4184, 11/2007, Volume 12, Issue 11, pp. 1026 - 1032
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2011, Volume 45, Issue 1, pp. 633 - 644
Journal Article
Psychopharmacology, ISSN 0033-3158, 9/2016, Volume 233, Issue 17, pp. 3269 - 3277
Anxiety disorders are the most common mental disorders in the USA. Characterized by feelings of uncontrollable apprehension, they are accompanied by physical,... 
Animal model | Neurosciences | Biomedicine | Depression | Anxiety | HPA axis | Pharmacology/Toxicology | Psychiatry | Neuropeptide | Stress | MC4 | CORTICOTROPIN-RELEASING HORMONE | SYSTEM | PSYCHIATRY | STRESS-INDUCED ANOREXIA | BEHAVIOR | IMMOBILIZATION STRESS | MC4 RECEPTOR | ELEVATED PLUS-MAZE | NEUROSCIENCES | BED NUCLEUS | FEMALE RATS | ETHANOL INTAKE | PHARMACOLOGY & PHARMACY | Hypothalamo-Hypophyseal System - drug effects | Receptors, Melanocortin - antagonists & inhibitors | Central Amygdaloid Nucleus - drug effects | Pituitary-Adrenal System - drug effects | Pituitary-Adrenal System - metabolism | Melanocyte-Stimulating Hormones - pharmacology | Rats | Male | Receptor, Melanocortin, Type 4 - metabolism | Basolateral Nuclear Complex - metabolism | Emotions - drug effects | Hypothalamo-Hypophyseal System - metabolism | Receptor, Melanocortin, Type 4 - drug effects | Animals | Anxiety Disorders | Neurotransmitter Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Behavior, Animal - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Central Amygdaloid Nucleus - metabolism | Corticosterone - blood | Basolateral Nuclear Complex - drug effects | Cell receptors | Polypeptides | Causes of | Physiological aspects | Health aspects | Amygdala (Brain) | Neuropeptides | Mental depression | Neuropsychology | Anxieties | Index Medicus | anxiety | neuropeptide | depression | animal model
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2013, Volume 33, Issue 10, pp. 4614 - 4622
After G-protein-coupled receptor activation and signaling at the plasma membrane, the receptor complex is often rapidly internalized via endocytic vesicles for... 
CYCLIC-AMP | INTRACARDIAC NEURONS | AKT ACTIVATION | I-H | PACAP-INDUCED INCREASE | DYNAMICS | TRAFFICKING | PROTEIN-COUPLED RECEPTORS | BETA-ARRESTIN | ENDOCYTOSIS | NEUROSCIENCES | Temperature | Action Potentials - genetics | Electric Stimulation | Humans | Brefeldin A - pharmacology | Male | Green Fluorescent Proteins - genetics | Transfection | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Endosomes - drug effects | Neurons - physiology | Female | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Neurons - drug effects | Thiazolidines - pharmacology | Cyclic AMP - metabolism | Action Potentials - drug effects | Animals, Newborn | Green Fluorescent Proteins - metabolism | Guinea Pigs | Drug Administration Schedule | Chlorides - pharmacology | Gene Expression Regulation - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Biophysics | Sulfonamides - pharmacology | Superior Cervical Ganglion - cytology | Barium Compounds - pharmacology | Hydrazones - pharmacology | Myocardium - cytology | Gene Expression Regulation - drug effects | Patch-Clamp Techniques | Animals | Signal Transduction - drug effects | Signal Transduction - physiology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | In Vitro Techniques | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 02/2016, Volume 101, pp. 291 - 308
The endogenous neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is secreted by both neuronal and non-neuronal cells in the brain and... 
Ion channel modulation | Pituitary adenylate cyclase-activating peptide (PACAP) | Extracellular-signal-regulated kinase (ERK) | G protein-coupled receptor (GPCR) | Kv4.2 | Protein kinase A (PKA) | Potassium channel | ALPHA-SUBUNITS | PACAP RECEPTOR | INTRINSIC EXCITABILITY | DIFFERENTIAL EXPRESSION | PROTEIN-KINASE | DOWN-REGULATION | EXTRACELLULAR DOMAIN | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | PHARMACOLOGY & PHARMACY | K+ CHANNELS | Embryo, Mammalian | Humans | Male | Neurons - cytology | Neurotransmitter Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Female | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Dendrites - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mutagenesis - genetics | Rats | Hippocampus - cytology | Mutation - genetics | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Shal Potassium Channels - metabolism | Animals | Signal Transduction - drug effects | Signal Transduction - physiology | Mice | Stroke (Disease) | Seizures (Medicine) | Potassium channels | Neurons | G proteins | Peptides | Protein kinases | Membrane proteins | Index Medicus
Journal Article
Journal of Vascular Research, ISSN 1018-1172, 05/2017, Volume 54, Issue 3, pp. 180 - 192
Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a multifunctional neuropeptide in the VIP/secretin/glucagon peptide superfamily. Two... 
Pituitary adenylate cyclase-activating polypeptide | PACAP-KO mice | Femoral arteries | VPAC1/VPAC2 receptors | Vasoactive intestinal peptide | Carotid arteries | PAC1 receptor | Vasomotor responses | SYSTEM | CELLS | PHYSIOLOGY | VASOACTIVE-INTESTINAL-PEPTIDE | RAT | VASCULAR-RESPONSES | PHARMACOLOGICAL CHARACTERIZATION | PERIPHERAL VASCULAR DISEASE | CEREBRAL-ARTERIES | VIP | EXPRESSION | RECEPTOR-BINDING | Vasodilator Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Genotype | Male | Peptide Fragments - pharmacology | Femoral Artery - drug effects | Mice, Knockout | Dose-Response Relationship, Drug | Femoral Artery - enzymology | Phenotype | Animals | Signal Transduction - drug effects | Vasoactive Intestinal Peptide - pharmacology | Carotid Artery, Common - enzymology | Receptors, Vasoactive Intestinal Polypeptide, Type I - agonists | Carotid Artery, Common - drug effects | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - agonists | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Vasodilation - drug effects | In Vitro Techniques | Pituitary Adenylate Cyclase-Activating Polypeptide - deficiency | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e108389 - e108389
Background: The neuropeptide Pituitary adenylate cyclase-activating polypeptide ( PACAP) plays pivotal roles in immunity and inflammation. So far, potential... 
ORAL INFECTION | IN-VITRO | VASOACTIVE-INTESTINAL-PEPTIDE | PACAP | MULTIDISCIPLINARY SCIENCES | IL-10 PRODUCTION | TOXOPLASMA-GONDII | MICE | INDUCTION | VIP | RECEPTORS | Ileitis - drug therapy | Toxoplasmosis - drug therapy | Intestine, Small - pathology | Mice, Inbred C57BL | Parasite Load | Ileitis - pathology | Toxoplasmosis - pathology | Animals | Immunity, Cellular - drug effects | Ileitis - parasitology | Time Factors | Pituitary Adenylate Cyclase-Activating Polypeptide - therapeutic use | Intestine, Small - drug effects | Mice | Pituitary Adenylate Cyclase-Activating Polypeptide - administration & dosage | Intestine, Small - immunology | Infection | Inflammation | T cells | Health aspects | Nitric oxide | Gastrointestinal diseases | Oxidative stress | Inflammatory bowel diseases | Adrenal glands | Liver | Prophylaxis | Interleukin 22 | Neuropeptides | Lymphocytes T | Infections | Macrophages | Immunity | Experiments | Lymph nodes | Interleukin 6 | Interleukin 4 | Microbiota | Ischemia | Lymphocytes | Intestine | Compartments | Rodents | Foxp3 protein | Spleen | Kidneys | Polypeptides | Cytokines | Ileitis | Complications | Immunomodulation | Therapeutic applications | Medical treatment | Leukocytes (neutrophilic) | Crohns disease | Medicine | Pituitary adenylate cyclase-activating polypeptide | Inflammatory bowel disease | Monocytes | Cysts | Lungs | Tumor necrosis factor | γ-Interferon | Interleukin 10 | Interferon | Hygiene | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article