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Genes and Development, ISSN 0890-9369, 05/2008, Volume 22, Issue 10, pp. 1276 - 1312
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more... 
Development | PDGF receptor | Platelet-derived growth factor | Fibrosis | Cancer | Receptors, Vascular Endothelial Growth Factor - physiology | Genetic Predisposition to Disease | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Embryo, Mammalian | Humans | Embryonic Development - genetics | Receptors, Platelet-Derived Growth Factor - genetics | Receptors, Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Organogenesis | Disease - etiology | Tissue Distribution | Platelet-Derived Growth Factor - metabolism | Animals | Models, Biological | Signal Transduction - physiology | Polymorphism, Single Nucleotide | Receptors, Vascular Endothelial Growth Factor - genetics | Bone and Bones - embryology | Nervous System - embryology | Platelet-Derived Growth Factor - physiology | Vascular Endothelial Growth Factor A - physiology | Cardiovascular System - embryology | development | platelet-derived growth factor | DEVELOPMENTAL BIOLOGY | FACTOR-B-CHAIN | FACTOR-RECEPTOR-BETA | CELL BIOLOGY | SIMIAN SARCOMA-VIRUS | GENETICS & HEREDITY | PDGF-ALPHA-RECEPTOR | FACTOR-A-CHAIN | TYROSINE KINASE INHIBITOR | cancer | fibrosis | SMOOTH-MUSCLE-CELLS | IDIOPATHIC HYPEREOSINOPHILIC SYNDROME | HEPARAN-SULFATE PROTEOGLYCANS | GASTROINTESTINAL STROMAL TUMORS | Tyrosine | Hematopoiesis | Pharmacology | Research | Chemical properties | Phosphotransferases | Health aspects | Review
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2007, Volume 117, Issue 10, pp. 2766 - 2777
Tumors produce multiple growth factors, but little is known about the interplay between various angiogenic factors in promoting tumor angiogenesis, growth, and... 
MEDICINE, RESEARCH & EXPERIMENTAL | INHIBITION | THERAPY | ALPHA-RECEPTOR | LYMPHANGIOGENESIS | FIBROBLAST-GROWTH-FACTOR | EMERGING MECHANISMS | CELL-GROWTH | CANCER | LYMPHATIC METASTASIS | BETA-RECEPTOR | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Humans | Fibroblast Growth Factor 2 - pharmacology | Endothelium, Vascular - drug effects | Fibrosarcoma - metabolism | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Platelet-Derived Growth Factor - genetics | Fibrosarcoma - pathology | Lung Neoplasms - secondary | Pericytes - pathology | Fibroblast Growth Factor 2 - metabolism | Capillaries | Fibrosarcoma - blood | Muscle, Smooth, Vascular - drug effects | Promoter Regions, Genetic | Signal Transduction | Proto-Oncogene Proteins c-sis | Pericytes - metabolism | Rats | Platelet-Derived Growth Factor - pharmacology | Mice, SCID | Muscle, Smooth, Vascular - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Fibroblast Growth Factor 2 - genetics | Endothelium, Vascular - metabolism | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Cell Movement | Complications and side effects | Causes of | Development and progression | Metastasis | Research | Neovascularization | Growth factors | MEDICIN OCH HÄLSOVETENSKAP | MEDICAL AND HEALTH SCIENCES
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2018, Volume 142, Issue 7, pp. 1322 - 1331
The platelet-derived growth factor (PDGF) signaling pathway plays important roles in development and progression of human cancers. In our study, we aimed to... 
platelet-derived growth factor | pathway analysis | pancreatic cancer susceptibility | single nucleotide polymorphism | genome-wide association study | ADENOCARCINOMA | SUSCEPTIBILITY LOCI | RECEPTOR | POLYMORPHISMS | STELLATE CELL | ONCOLOGY | PDGF | FUNCTIONAL VARIATION | EXPRESSION | EPIDEMIOLOGY | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Proto-Oncogene Proteins c-sis - genetics | Humans | Middle Aged | Genotype | Male | Pancreatic Neoplasms - genetics | Case-Control Studies | Crk-Associated Substrate Protein - genetics | Genetic Variation | Female | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Platelet-derived growth factor | RNA | Oncology, Experimental | Genes | Genomics | Development and progression | Disease susceptibility | Research | Risk factors | Quantitative genetics | Pancreatic cancer | Genetic research | Genetic aspects | Single nucleotide polymorphisms | Health aspects | Cancer | Haplotypes | Genomes | Males | Tissues | Confidence intervals | Genotype & phenotype | Signal transduction | Regression models | Growth factors | Genotypes | Statistical analysis | Lymphoblastoid cell lines | Health risks | Tumor cell lines | Regression analysis | Risk analysis | Gene expression | Loci | Carriers | Quantitative trait loci | Genetic variance | Signaling | Data sets | Alleles | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 01/2009, Volume 69, Issue 1, pp. 369 - 378
Journal Article
Journal of Internal Medicine, ISSN 0954-6820, 01/2018, Volume 283, Issue 1, pp. 16 - 44
Platelet‐derived growth factor ( PDGF ) isoforms and their receptors have important roles during embryogenesis, particularly in the development of various... 
kinase | receptor | inhibitor | malignancy | signal transduction | PDGF | CANCER-ASSOCIATED FIBROBLASTS | MULTICENTER PHASE-II | TEL-PDGFR-BETA | FACTOR-B-CHAIN | BLOOD-BRAIN-BARRIER | MEDICINE, GENERAL & INTERNAL | FACTOR-BETA-RECEPTOR | TYROSINE KINASE INHIBITOR | SMOOTH-MUSCLE-CELLS | COMPARATIVE GENOMIC HYBRIDIZATION | GASTROINTESTINAL STROMAL TUMORS | Neoplasms - metabolism | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Signal Transduction | Humans | Carcinogenesis - genetics | Receptors, Platelet-Derived Growth Factor - genetics | Carcinogenesis - metabolism | Platelet-Derived Growth Factor - genetics | Neoplasms - drug therapy | Platelet-Derived Growth Factor - metabolism | Animals | Neoplasms - genetics | Receptors, Platelet-Derived Growth Factor - metabolism | Ligands | Antineoplastic Agents - pharmacology | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Platelet-Derived Growth Factor - antagonists & inhibitors | Cellular signal transduction | Platelet-derived growth factor | Tumors | Cell proliferation | Mesenchyme | Leukemia | Homeostasis | Proteins | Angiogenesis | Receptors | Embryogenesis | Cell growth | Atherosclerosis | Fibroblasts | Tumorigenesis | Autocrine signalling | Growth factors | Translocation | Cell survival | Wound healing | Organs | Stroma | Embryonic growth stage | Arteriosclerosis | Isoforms | Fibrosis | Skin | Mutation | Cancer | Basic Medicine | Biological Sciences | Medical and Health Sciences | Medicin och hälsovetenskap | Cell and Molecular Biology | Cell Biology | Naturvetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences | Cellbiologi | Cell- och molekylärbiologi
Journal Article
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 08/2013, Volume 5, Issue 8, pp. a009100 - a009100
Journal Article
The Oncologist, ISSN 1083-7159, 06/2015, Volume 20, Issue 6, pp. 660 - 673
Journal Article