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Cell Cycle, ISSN 1538-4101, 05/2015, Volume 14, Issue 10, pp. 1507 - 1516
We recently demonstrated that conditioned media (CM) from osteocytes enhances myogenic differentiation of myoblasts, suggesting that signaling from bone may be... 
EP4 | bone-muscle crosstalk | Prostaglandin E | proliferation | myogenesis | reactive oxygen species | Bone-muscle crosstalk | Reactive oxygen species | Proliferation | Myogenesis | Immunohistochemistry | Reactive Oxygen Species - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Alprostadil - analogs & derivatives | Myoblasts - drug effects | Muscle, Skeletal - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Alprostadil - pharmacology | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Thiophenes - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Triazoles - pharmacology | Animals | Signal Transduction - drug effects | Acetylcysteine - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - agonists | Cell Proliferation - drug effects | Mice | G1 Phase Cell Cycle Checkpoints - drug effects | Receptors, Prostaglandin E, EP2 Subtype - agonists | Receptors, Prostaglandin E, EP3 Subtype - agonists | Index Medicus
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2015, Volume 309, Issue 10, pp. 639 - 649
Obesity, a known risk factor for pancreatic cancer, is associated with inflammation and insulin resistance. Proinflammatory prostaglandin E2 (PGE(2)) and... 
Prostaglandin E2 | Obesity | Mammalian target of rapamycin complex 1 | Pancreatic cancer | PHYSIOLOGY | HIGH-FAT DIET | COUPLED RECEPTOR | COLON CARCINOGENESIS | KRAS(G12D) MOUSE MODEL | CELL BIOLOGY | CANCER GROWTH | BREAST-CANCER | INSULIN | pancreatic cancer | CYCLIC-AMP | prostaglandin E2 | PROTEIN S6 PHOSPHORYLATION | mammalian target of rapamycin complex 1 | obesity | TUMOR MICROENVIRONMENT | Cyclic AMP-Dependent Protein Kinases - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP2 Subtype - metabolism | TOR Serine-Threonine Kinases - metabolism | Calcium - metabolism | Humans | Receptors, Prostaglandin E, EP2 Subtype - genetics | Gene Expression Regulation - physiology | Multiprotein Complexes - genetics | Receptors, Prostaglandin E, EP1 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Mechanistic Target of Rapamycin Complex 1 | Dinoprostone - metabolism | Interleukin-23 Subunit p19 - metabolism | Multiprotein Complexes - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | TOR Serine-Threonine Kinases - genetics | Interleukin-23 Subunit p19 - genetics | Cell Line, Tumor | Cyclic AMP - genetics | Cyclic AMP - metabolism | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Index Medicus | Call for Papers
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2011, Volume 31, Issue 5, pp. 1049 - 1058
OBJECTIVE—One of the hallmarks of inflammation is lymphangiogesis that drains the interstitial fluids. During chronic inflammation, angiogenesis is induced by... 
lymphangiogenesis | endothelium | prostaglandins | vascular biology | angiogenesis | Membrane Glycoproteins - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Granulation Tissue - physiopathology | Glycoproteins - metabolism | Male | Lymphatic Vessels - drug effects | Granulation Tissue - drug effects | Lymphatic Vessels - metabolism | Time Factors | Receptors, Prostaglandin E, EP4 Subtype - deficiency | Injections, Subcutaneous | Intramolecular Oxidoreductases - metabolism | Fibroblasts - metabolism | Pyrazoles - pharmacology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - genetics | Celecoxib | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Fibroblast Growth Factor 2 - administration & dosage | Sulfonamides - pharmacology | Granulation Tissue - metabolism | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Mice, Knockout | Dinoprostone - metabolism | Lymphangiogenesis - drug effects | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Receptors, Prostaglandin E, EP3 Subtype - deficiency | Signal Transduction - drug effects | Vascular Endothelial Growth Factor C - metabolism | Fibroblasts - drug effects | Prostaglandin-E Synthases | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Mice | Lymphatic Vessels - physiopathology | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 2015, Volume 11, Issue 10, pp. e1005542 - e1005542
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2016, Volume 173, Issue 6, pp. 992 - 1004
Journal Article
Circulation, ISSN 0009-7322, 01/2014, Volume 129, Issue 4, pp. 487 - 496
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 27, pp. 8397 - 8402
The antidiuretic hormone arginine vasopressin is a systemic effector in urinary concentration. However, increasing evidence suggests that other locally... 
Water homeostasis | Cyclooxygenase | Antidiuretic hormone | Gene targeting | Arachidonic acid | arachidonic acid | CELLS | RAT-KIDNEY | MULTIDISCIPLINARY SCIENCES | gene targeting | cyclooxygenase | antidiuretic hormone | MICE LACKING | ESCAPE | INACTIVATION | GENE | water homeostasis | WATER CHANNEL | VASOPRESSIN-INDUCED ANTIDIURESIS | EXPRESSION | CAMP PRODUCTION | Dinoprostone - biosynthesis | Kidney Tubules, Collecting - cytology | MAP Kinase Signaling System | RNA Interference | Pyrrolidinones - pharmacology | Cell Membrane - metabolism | Cyclic AMP - metabolism | Cell Membrane - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Cell Line | Dinoprostone - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Water - metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Aquaporin 2 - metabolism | Kidney Tubules, Collecting - metabolism | Animals | Cyclic AMP Response Element-Binding Protein - metabolism | Dinoprostone - analogs & derivatives | Kidney Concentrating Ability - genetics | Primary Cell Culture | Aquaporin 2 - genetics | Microscopy, Fluorescence | Prostaglandins | Aquaporins | Physiological aspects | Urination disorders | Genetic aspects | Research | Diagnosis | Risk factors | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 31, pp. 12949 - 12954
In the kidney, the actions of vasopressin on its type-2 receptor (V2R) induce increased water reabsorption alongside polyphosphorylation and membrane targeting... 
Urine | Receptors | Phosphorylation | Prostaglandins | Kidneys | Nondestructive testing | Nephrogenic diabetes insipidus | Agonists | Cell membranes | Kidney cells | Drug development/discovery | Water balance | Autocoid | Lipid mediators | Cell signaling | RENAL EPITHELIAL-CELLS | LOCALIZATION | drug development/discovery | PHOSPHORYLATION | SUBTYPES | MULTIDISCIPLINARY SCIENCES | MEMBRANE INSERTION | RATS | water balance | PLASMA-MEMBRANE | lipid mediators | COLLECTING DUCT | EP4 RECEPTOR | cell signaling | autocoid | WATER | Rats, Wistar | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Receptors, Vasopressin - metabolism | Immunoblotting | Male | Vasopressins - metabolism | Protein Transport - drug effects | Alprostadil - analogs & derivatives | Dose-Response Relationship, Drug | Kidney - metabolism | Diabetes Insipidus, Nephrogenic - genetics | Pyrrolidinones - pharmacology | Cell Membrane - metabolism | Diabetes Insipidus, Nephrogenic - prevention & control | Phosphorylation - drug effects | Cyclic AMP - metabolism | Cell Membrane - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Cell Line | Dinoprostone - pharmacology | Kidney - drug effects | Receptors, Prostaglandin E, EP2 Subtype - genetics | Alprostadil - pharmacology | Rats | Vasopressins - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Aquaporin 2 - metabolism | Microscopy, Confocal | Animals | Dogs | Receptors, Vasopressin - genetics | Dinoprostone - analogs & derivatives | Antidiuretic Hormone Receptor Antagonists | Aquaporin 2 - genetics | Receptors, Prostaglandin E, EP2 Subtype - agonists | Diabetes Insipidus, Nephrogenic - metabolism | Aquaporins | Diabetes insipidus | Physiological aspects | Development and progression | Health aspects | Vasopressin | Agonists (Biochemistry) | T cell receptors | Diabetes | Rodents | Index Medicus | Biological Sciences | discovery | drug development
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 121, Issue 11, pp. 1995 - 2007
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0162532 - e0162532
Lymphangiogenesis plays an important role in homeostasis, metabolism, and immunity, and also occurs during wound-healing. Here, we examined the roles of... 
SUBTYPE | LYMPHATIC VESSELS | INFLAMMATORY-BOWEL-DISEASE | ANGIOGENESIS | CLONING | MULTIDISCIPLINARY SCIENCES | MOUSE | C-TERMINAL TAIL | TUMOR-GROWTH | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Ear - physiology | Male | Receptors, Prostaglandin E, EP4 Subtype - deficiency | Wound Healing - drug effects | Macrophages - immunology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Prostaglandin-E Synthases - metabolism | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP3 Subtype - genetics | Macrophages - cytology | Gene Knockout Techniques | Vascular Endothelial Growth Factor D - biosynthesis | Lymphangiogenesis - drug effects | Up-Regulation - drug effects | Macrophages - metabolism | Animals | Receptors, Prostaglandin E, EP3 Subtype - deficiency | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Mice | CD11b Antigen - metabolism | Vascular Endothelial Growth Factor C - biosynthesis | COX-2 inhibitors | Care and treatment | Wound healing | Analysis | Synthetic prostaglandins E | Hyaluronic acid | Macrophages | Vascular endothelial growth factor | Wounds and injuries | Cell proliferation | Homeostasis | Prostaglandin E2 | Biochemistry | Immunity | Experiments | Recruitment | Hyaluronan | Angiogenesis | Receptors | Prostaglandin E receptors | Rodents | Animal tissues | Tumor necrosis factor-TNF | Physiology | Prostaglandin E | Medical research | CD11b antigen | Granulation | Cytokines | Cloning | Inflammation | Pharmacology | Celecoxib | Metabolism | Prostaglandin-E synthase | Endothelial cells | Medicine | Pathology | Signaling | Inhibitors | Ear | Healing | Cyclooxygenase-2 | Index Medicus
Journal Article
Science, ISSN 0036-8075, 03/2016, Volume 351, Issue 6279, pp. 1333 - 1338
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 1/2014, Volume 143, Issue 1, pp. 19 - 31
Journal Article