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European Journal of Immunology, ISSN 0014-2980, 10/2011, Volume 41, Issue 10, pp. 2840 - 2851
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2015, Volume 14, Issue 10, pp. 1507 - 1516
We recently demonstrated that conditioned media (CM) from osteocytes enhances myogenic differentiation of myoblasts, suggesting that signaling from bone may be... 
EP4 | bone-muscle crosstalk | Prostaglandin E | proliferation | myogenesis | reactive oxygen species | Bone-muscle crosstalk | Reactive oxygen species | Proliferation | Myogenesis | Immunohistochemistry | Reactive Oxygen Species - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Alprostadil - analogs & derivatives | Myoblasts - drug effects | Muscle, Skeletal - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Alprostadil - pharmacology | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Thiophenes - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Triazoles - pharmacology | Animals | Signal Transduction - drug effects | Acetylcysteine - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - agonists | Cell Proliferation - drug effects | Mice | G1 Phase Cell Cycle Checkpoints - drug effects | Receptors, Prostaglandin E, EP2 Subtype - agonists | Receptors, Prostaglandin E, EP3 Subtype - agonists | Index Medicus
Journal Article
STEM CELLS, ISSN 1066-5099, 09/2016, Volume 34, Issue 9, pp. 2290 - 2305
Cancer stem‐like cells (SLC) resist conventional therapies, necessitating searches for SLC‐specific targets. We established that cyclo‐oxygenase(COX)‐2... 
EP4 | NOTCH/WNT | Breast cancer | Stem‐like cell | Cyclo‐oxygenase‐2 | Cyclo-oxygenase-2 | Stem-like cell | MIGRATION | TARGET | CYCLOOXYGENASE-2 | ANGIOGENESIS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | PROSTANOID RECEPTORS | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | LYMPHANGIOGENESIS | INHIBITORS | HEMATOLOGY | EXPRESSION | Signal Transduction | Neoplasm Invasiveness | Receptors, Notch - metabolism | Humans | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Phosphatidylinositol 3-Kinases - metabolism | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Breast Neoplasms - enzymology | Phenotype | Animals | Breast Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Breast Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Female | Mice | Proto-Oncogene Proteins c-akt - metabolism | Neoplasm Micrometastasis - pathology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | COX-2 inhibitors | Prostaglandins | DNA microarrays | Endothelial growth factors | RNA | Analysis | Stem cells | Development and progression | Transplantation | Metastasis | Intermediate filament proteins | Genes | Rodents | Regulations | Severe combined immunodeficiency | Leukocyte migration | Mesenchyme | Oct-4 protein | Lung | Gene regulation | AKT protein | E-cadherin | Prostaglandin endoperoxide synthase | Metastases | Allografts | CD44 antigen | Animal tissues | Down-regulation | Localization | Vascular endothelial growth factor | Interleukin 2 receptors | Markers | Gene expression | Spheroids | 1-Phosphatidylinositol 3-kinase | Oxygenase | Overexpression | Inhibitors | Cell lines | Breast | Cyclooxygenase-2 | Colonization | Cell migration | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2017, Volume 161, Issue 6, pp. 1570 - 1578
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2011, Volume 31, Issue 5, pp. 1049 - 1058
OBJECTIVE—One of the hallmarks of inflammation is lymphangiogesis that drains the interstitial fluids. During chronic inflammation, angiogenesis is induced by... 
lymphangiogenesis | endothelium | prostaglandins | vascular biology | angiogenesis | Membrane Glycoproteins - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Granulation Tissue - physiopathology | Glycoproteins - metabolism | Male | Lymphatic Vessels - drug effects | Granulation Tissue - drug effects | Lymphatic Vessels - metabolism | Time Factors | Receptors, Prostaglandin E, EP4 Subtype - deficiency | Injections, Subcutaneous | Intramolecular Oxidoreductases - metabolism | Fibroblasts - metabolism | Pyrazoles - pharmacology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - genetics | Celecoxib | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Fibroblast Growth Factor 2 - administration & dosage | Sulfonamides - pharmacology | Granulation Tissue - metabolism | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Mice, Knockout | Dinoprostone - metabolism | Lymphangiogenesis - drug effects | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Receptors, Prostaglandin E, EP3 Subtype - deficiency | Signal Transduction - drug effects | Vascular Endothelial Growth Factor C - metabolism | Fibroblasts - drug effects | Prostaglandin-E Synthases | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Mice | Lymphatic Vessels - physiopathology | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2014, Volume 20, Issue 5, pp. 1259 - 1273
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2015, Volume 309, Issue 10, pp. 639 - 649
Obesity, a known risk factor for pancreatic cancer, is associated with inflammation and insulin resistance. Proinflammatory prostaglandin E2 (PGE(2)) and... 
Prostaglandin E2 | Obesity | Mammalian target of rapamycin complex 1 | Pancreatic cancer | PHYSIOLOGY | HIGH-FAT DIET | COUPLED RECEPTOR | COLON CARCINOGENESIS | KRAS(G12D) MOUSE MODEL | CELL BIOLOGY | CANCER GROWTH | BREAST-CANCER | INSULIN | pancreatic cancer | CYCLIC-AMP | prostaglandin E2 | PROTEIN S6 PHOSPHORYLATION | mammalian target of rapamycin complex 1 | obesity | TUMOR MICROENVIRONMENT | Cyclic AMP-Dependent Protein Kinases - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP2 Subtype - metabolism | TOR Serine-Threonine Kinases - metabolism | Calcium - metabolism | Humans | Receptors, Prostaglandin E, EP2 Subtype - genetics | Gene Expression Regulation - physiology | Multiprotein Complexes - genetics | Receptors, Prostaglandin E, EP1 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Mechanistic Target of Rapamycin Complex 1 | Dinoprostone - metabolism | Interleukin-23 Subunit p19 - metabolism | Multiprotein Complexes - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | TOR Serine-Threonine Kinases - genetics | Interleukin-23 Subunit p19 - genetics | Cell Line, Tumor | Cyclic AMP - genetics | Cyclic AMP - metabolism | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Index Medicus | Call for Papers
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2016, Volume 173, Issue 6, pp. 992 - 1004
Journal Article
Cancer Science, ISSN 1347-9032, 09/2014, Volume 105, Issue 9, pp. 1142 - 1151
We previously established that COX ‐2 overexpression promotes breast cancer progression and metastasis. As long‐term use of COX ‐2 inhibitors ( COX ‐2i) can... 
macrophages | cyclooxygenase 2 | 00015986 | Cancer stem cells | 4 subtype | prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Macrophages | RQ-00015986 | Cyclooxygenase 2 | FACTOR VEGF | ANTAGONIST | prostaglandin E2 receptor EP4 subtype | HUMAN BREAST-CANCER | MURINE | PROSTANOID RECEPTORS | ONCOLOGY | GROWTH | TUMOR-ASSOCIATED MACROPHAGES | CYCLOOXYGENASE-2 EXPRESSION | UP-REGULATION | PROGRESSION | Lung Neoplasms - drug therapy | Neoplasm Transplantation | Pyrazoles - therapeutic use | Cell Proliferation | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Molecular Targeted Therapy | Benzamides - therapeutic use | Lung Neoplasms - secondary | Receptors, Prostaglandin E, EP4 Subtype - antagonists & inhibitors | Mammary Neoplasms, Experimental - pathology | Female | Mammary Neoplasms, Experimental - blood supply | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Lymphangiogenesis | Lung Neoplasms - blood supply | Mammary Neoplasms, Experimental - drug therapy | Pyrazoles - pharmacology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Lymphatic Metastasis | Neoplastic Stem Cells | Celecoxib | Tumor Burden | Sulfonamides - pharmacology | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Mice, Inbred C3H | Adenocarcinoma - blood supply | Macrophages - metabolism | Animals | Sulfonamides - therapeutic use | Neovascularization, Pathologic - drug therapy | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Mice | Apoptosis | Drug Screening Assays, Antitumor | Index Medicus | Original
Journal Article