Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1313) 1313
science & technology (1145) 1145
life sciences & biomedicine (1051) 1051
humans (1027) 1027
mice (624) 624
male (589) 589
female (491) 491
dinoprostone - metabolism (488) 488
receptors, prostaglandin e - metabolism (477) 477
dinoprostone - pharmacology (463) 463
biological and medical sciences (461) 461
receptors, prostaglandin e, ep4 subtype (444) 444
cells, cultured (369) 369
rats (364) 364
receptors, prostaglandin e, ep4 subtype - metabolism (351) 351
lipids (341) 341
signal transduction (318) 318
receptors, prostaglandin e - genetics (307) 307
medical sciences (303) 303
prostaglandin e2 (296) 296
receptors, prostaglandin e, ep2 subtype (271) 271
cell biology (248) 248
mice, inbred c57bl (237) 237
fundamental and applied biological sciences. psychology (220) 220
cyclic amp - metabolism (216) 216
biochemistry & molecular biology (214) 214
cyclooxygenase 2 - metabolism (211) 211
mice, knockout (208) 208
rna, messenger - metabolism (205) 205
inflammation (204) 204
prostaglandin e (199) 199
prostaglandins (199) 199
receptors, prostaglandin e - agonists (198) 198
rats, sprague-dawley (197) 197
receptors, prostaglandin e - physiology (193) 193
gene expression (188) 188
signal transduction - drug effects (179) 179
pharmacology & pharmacy (175) 175
prostaglandins e (175) 175
dose-response relationship, drug (174) 174
receptors, prostaglandin e, ep2 subtype - metabolism (171) 171
cell line (169) 169
reverse transcriptase polymerase chain reaction (157) 157
abridged index medicus (155) 155
proteins (151) 151
receptors, prostaglandin e, ep3 subtype (151) 151
cell line, tumor (148) 148
oncology (145) 145
receptors, prostaglandin e, ep4 subtype - genetics (144) 144
rodents (142) 142
receptors (141) 141
receptors, prostaglandin e - antagonists & inhibitors (140) 140
disease models, animal (132) 132
immunology (132) 132
dinoprostone - physiology (127) 127
receptors, prostaglandin e, ep1 subtype (126) 126
immunohistochemistry (125) 125
physiological aspects (122) 122
neurosciences (120) 120
research article (120) 120
alprostadil - pharmacology (119) 119
research (119) 119
middle aged (116) 116
physiology (116) 116
rna, messenger - genetics (116) 116
endocrinology & metabolism (113) 113
alprostadil - analogs & derivatives (111) 111
blotting, western (111) 111
prostaglandin (110) 110
cyclooxygenase 2 - genetics (109) 109
neurosciences & neurology (106) 106
kinases (102) 102
pge2 (101) 101
receptors, prostaglandin e, ep4 subtype - antagonists & inhibitors (100) 100
signal transduction - physiology (99) 99
cyclic amp-dependent protein kinases - metabolism (98) 98
receptors, prostaglandin - metabolism (96) 96
adult (94) 94
tumors (94) 94
cyclooxygenase-2 (93) 93
medicine (93) 93
cyclooxygenase 2 (92) 92
multidisciplinary sciences (92) 92
science & technology - other topics (92) 92
dinoprostone - analogs & derivatives (91) 91
analysis (90) 90
gene expression regulation - drug effects (90) 90
prostaglandin-endoperoxide synthases - metabolism (90) 90
time factors (90) 90
cytokines (88) 88
phosphorylation (88) 88
calcium - metabolism (87) 87
receptors, prostaglandin e, ep4 subtype - agonists (86) 86
cell proliferation (85) 85
aged (84) 84
cancer (83) 83
pge (82) 82
pharmacology. drug treatments (82) 82
receptors, prostaglandin - genetics (81) 81
neurology (80) 80
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation
by Mo, Chenglin and Zhao, Ruonan and Vallejo, Julian and Igwe, Orisa and Bonewald, Lynda and Wetmore, Lori and Brotto, Marco
Cell cycle (Georgetown, Tex.), ISSN 1538-4101, 05/2015, Volume 14, Issue 10, pp. 1507 - 1516
EP4 | bone-muscle crosstalk | Prostaglandin E | proliferation | myogenesis | reactive oxygen species | Bone-muscle crosstalk | Reactive oxygen species | Proliferation | Myogenesis | Immunohistochemistry | Reactive Oxygen Species - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Alprostadil - analogs & derivatives | Myoblasts - drug effects | Muscle, Skeletal - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - genetics | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Alprostadil - pharmacology | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Thiophenes - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Triazoles - pharmacology | Animals | Signal Transduction - drug effects | Acetylcysteine - pharmacology | Receptors, Prostaglandin E, EP1 Subtype - agonists | Cell Proliferation - drug effects | Mice | G1 Phase Cell Cycle Checkpoints - drug effects | Receptors, Prostaglandin E, EP2 Subtype - agonists | Receptors, Prostaglandin E, EP3 Subtype - agonists | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Roles of Prostaglandin E2–EP3/EP4 Receptor Signaling in the Enhancement of Lymphangiogenesis During Fibroblast Growth Factor-2–Induced Granulation Formation
by Hosono, Kanako and Suzuki, Tatsunori and Tamaki, Hideaki and Sakagami, Hiroyuki and Hayashi, Izumi and Narumiya, Shuh and Alitalo, Kari and Majima, Masataka
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 05/2011, Volume 31, Issue 5, pp. 1049 - 1058
lymphangiogenesis | endothelium | prostaglandins | vascular biology | angiogenesis | Fundamental and applied biological sciences. Psychology | Cardiology. Vascular system | Blood vessels and receptors | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Medical sciences | Vertebrates: cardiovascular system | Blood and lymphatic vessels | Membrane Glycoproteins - metabolism | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Granulation Tissue - physiopathology | Glycoproteins - metabolism | Male | Lymphatic Vessels - drug effects | Granulation Tissue - drug effects | Lymphatic Vessels - metabolism | Time Factors | Receptors, Prostaglandin E, EP4 Subtype - deficiency | Injections, Subcutaneous | Intramolecular Oxidoreductases - metabolism | Fibroblasts - metabolism | Pyrazoles - pharmacology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Cells, Cultured | Receptors, Prostaglandin E, EP3 Subtype - genetics | Receptors, Prostaglandin E, EP1 Subtype - genetics | Celecoxib | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Fibroblast Growth Factor 2 - administration & dosage | Sulfonamides - pharmacology | Granulation Tissue - metabolism | Receptors, Prostaglandin E, EP1 Subtype - metabolism | Mice, Knockout | Dinoprostone - metabolism | Lymphangiogenesis - drug effects | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Receptors, Prostaglandin E, EP3 Subtype - deficiency | Signal Transduction - drug effects | Vascular Endothelial Growth Factor C - metabolism | Fibroblasts - drug effects | Prostaglandin-E Synthases | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Mice | Lymphatic Vessels - physiopathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Mesenchymal stem cell inhibition of T‐helper 17 cell‐ differentiation is triggered by cell–cell contact and mediated by prostaglandin E2 via the EP4 receptor
by Duffy, Michelle M and Pindjakova, Jana and Hanley, Shirley A and McCarthy, Cathal and Weidhofer, Gudrun A and Sweeney, Eva M and English, Karen and Shaw, Georgina and Murphy, J. Mary and Barry, Frank P and Mahon, Bernard P and Belton, Orina and Ceredig, Rhodri and Griffin, Matthew D
European journal of immunology, ISSN 0014-2980, 10/2011, Volume 41, Issue 10, pp. 2840 - 2851
T helper cells | Immunosuppression | Stem cells | Mesenchymal stem cells | Th17 cells | Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Proliferation | Dinoprostone - biosynthesis | Coculture Techniques | Interleukin-2 Receptor alpha Subunit - biosynthesis | Mesenchymal Stromal Cells - immunology | Th17 Cells - drug effects | Flow Cytometry | Th17 Cells - metabolism | Polymerase Chain Reaction | Female | Cell Differentiation | Mesenchymal Stromal Cells - physiology | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Mesenchymal Stromal Cells - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Lymphocyte Activation | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Cell Communication | Interleukin-17 - biosynthesis | Blotting, Western | Indomethacin - pharmacology | Dinoprostone - metabolism | Animals | Interleukin-17 - antagonists & inhibitors | Th17 Cells - immunology | Mice | Mice, Inbred BALB C | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Prostaglandin E-2 suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection
by Wan, Min and Tang, Xiao and Rekha, Rokeya Sultana and Muvva, S. S. V. Jagadeeswara Rao and Brighenti, Susanna and Agerberth, Birgitta and Haeggstrom, Jesper Z
The FASEB journal, ISSN 0892-6638, 05/2018, Volume 32, Issue 5, pp. 2827 - 2840
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cyclic AMP-Dependent Protein Kinases - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Cell Line | Dinoprostone - pharmacology | Macrophages - pathology | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Humans | Antimicrobial Cationic Peptides - biosynthesis | Autophagy - drug effects | Receptors, Calcitriol - biosynthesis | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Macrophages - metabolism | Tuberculosis - therapy | Signal Transduction - drug effects | Calcitriol - pharmacology | Mycobacterium tuberculosis - metabolism | Tuberculosis - metabolism | Macrophages - microbiology | Receptors, Prostaglandin E, EP2 Subtype - agonists | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Tuberculosis - pathology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text T cell–intrinsic prostaglandin E 2 -EP2/EP4 signaling is critical in pathogenic T H 17 cell–driven inflammation
by Lee, Jinju and Aoki, Tomohiro and Thumkeo, Dean and Siriwach, Ratklao and Yao, Chengcan and Narumiya, Shuh
Journal of allergy and clinical immunology, ISSN 0091-6749, 02/2019, Volume 143, Issue 2, pp. 631 - 643
Psoriasis | pathogenic T | IL-23 receptor | nuclear factor κ light chain enhancer of activated B cells | prostaglandin E | cAMP-responsive element binding protein 1 | 17 cells | prostaglandin E receptor EP4 | signal transducer and activator of transcription 3 | prostaglandin E receptor EP2 | Psoriasis - immunology | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Signal Transduction | Imiquimod | Humans | Mice, Inbred C57BL | Receptors, Prostaglandin E, EP2 Subtype - genetics | Cells, Cultured | Gene Expression Profiling | Inflammation - immunology | Mice, Knockout | Dinoprostone - metabolism | Animals | Interleukin-23 - metabolism | Th17 Cells - immunology | Mice | Cyclic AMP - metabolism | Disease Models, Animal | Receptors, Prostaglandin E, EP4 Subtype - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Prostaglandin E-2 receptor EP4 regulates cell migration through Orai1
by Osawa, Kohei and Umemura, Masanari and Nakakaji, Rina and Tanaka, Ryo and Islam, Rafikul Md and Nagasako, Akane and Fujita, Takayuki and Yokoyama, Utako and Koizumi, Toshiyuki and Mitsudo, Kenji and Ishikawa, Yoshihiro
Cancer science, ISSN 1347-9032, 01/2020, Volume 111, Issue 1, pp. 160 - 174
Life Sciences & Biomedicine | Oncology | Science & Technology | ORAI1 Protein - metabolism | Phosphorylation - physiology | Calcium - metabolism | Carcinoma, Squamous Cell - metabolism | Humans | Receptors, Prostaglandin E, EP2 Subtype - genetics | RNA, Messenger - metabolism | Cell Movement - physiology | Animals | MCF-7 Cells | Cell Line, Tumor | Signal Transduction - physiology | Tongue Neoplasms - metabolism | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Phosphorylation | Immunoprecipitation | Leukocyte migration | Oral cancer | Laboratories | Lung cancer | Colorectal cancer | STIM1 protein | Prostaglandin E2 | Intracellular signalling | mRNA | Prostaglandin receptors | Metastasis | Kinases | Cancer therapies | Calcium influx | Metastases | Cell adhesion & migration | Proteins | Signal transduction | Cell growth | Surgery | Prostaglandin E | Calcium channels | Squamous cell carcinoma | Immunoglobulins | Calcium (intracellular) | Extracellular signal-regulated kinase | Breast cancer | Tumor cell lines | Gene expression | Orai1 protein | Variance analysis | 1-Phosphatidylinositol 3-kinase | Medical prognosis | Kidney cancer | Protein expression | Agonists | Prostate cancer | Calcium (extracellular) | Cell migration | Cervical cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Protective role of mPGES-1 (microsomal prostaglandin E synthase-1)-derived PGE 2 (prostaglandin E 2 ) and the endothelial EP4 (prostaglandin E receptor) in vascular responses to injury
by Hao, Huifeng and Hu, Sheng and Wan, Qing and Xu, Chuansheng and Chen, Hong and Zhu, Liyuan and Xu, Zhenyu and Meng, Jian and Breyer, Richard M and Li, Nailin and Liu, De-Pei and FitzGerald, Garret A and Wang, Miao
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2018, Volume 38, Issue 5, pp. 1115 - 1124
Vascular remodeling | Prostaglandin receptor | Prostaglandin E synthases | Prostanoid | Endothelium | Femoral Artery - pathology | Leukocytes - pathology | Cell Proliferation | Vascular System Injuries - genetics | Humans | Vascular System Injuries - enzymology | Male | Femoral Artery - enzymology | Vascular System Injuries - pathology | Femoral Artery - injuries | Neointima | Receptors, Prostaglandin E, EP4 Subtype - deficiency | Prostaglandin-E Synthases - genetics | Female | Disease Models, Animal | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Re-Epithelialization | Receptors, Prostaglandin E, EP4 Subtype - genetics | Receptors, Epoprostenol - metabolism | Prostaglandin-E Synthases - metabolism | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Receptors, Epoprostenol - deficiency | Cell Adhesion | Prostaglandin-E Synthases - deficiency | Mice, Knockout | Dinoprostone - metabolism | Receptors, Epoprostenol - genetics | Animals | Endothelial Cells - pathology | Endothelial Cells - enzymology | Leukocytes - metabolism | Muscle, Smooth - pathology | Muscle, Smooth - enzymology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Direct growth-inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA-mediated mechanism
by Schmidt, Andrea, MD and Sinnett-Smith, James, BSc and Young, Steven, PhD and Chang, Hui-Hua, PhD and Hines, O. Joe, MD and Dawson, David W., MD and Rozengurt, Enrique, PhD and Eibl, Guido, MD
Surgery, ISSN 0039-6060, 2017, Volume 161, Issue 6, pp. 1570 - 1578
Surgery | Life Sciences & Biomedicine | Science & Technology | Intracellular Signaling Peptides and Proteins - pharmacology | Dinoprostone - pharmacology | Receptors, Prostaglandin E, EP2 Subtype - metabolism | Humans | Middle Aged | Pancreas - cytology | Pancreatic Neoplasms - pathology | Gene Expression Regulation | Male | Receptors, Prostaglandin E, EP1 Subtype - genetics | Cell Line, Tumor - drug effects | Cyclooxygenase 2 - drug effects | Carcinoma, Pancreatic Ductal - pathology | Blotting, Western | Receptors, Prostaglandin E, EP2 Subtype - drug effects | Phosphorylation - genetics | Sensitivity and Specificity | Cyclooxygenase 2 - metabolism | Female | Aged | Cell Proliferation - drug effects | Phosphorylation - drug effects | Receptors, Prostaglandin E, EP4 Subtype - drug effects | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Medical research | COX-2 inhibitors | Medical colleges | Growth | Pancreatic cancer | Analysis | Prostaglandins E | Medicine, Experimental | DNA synthesis | Rankings | Gene expression | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
by Boniface, Katia and Bak-Jensen, Kristian S and Li, Ying and Blumenschein, Wendy M and McGeachy, Mandy J and McClanahan, Terrill K and McKenzie, Brent S and Kastelein, Robert A and Cua, Daniel J and De Malefyt, René Waal
The Journal of experimental medicine, ISSN 0022-1007, 03/2009, Volume 206, Issue 3, pp. 535 - 548
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Interleukin-1beta - pharmacology | Coculture Techniques | Humans | Receptors, Interleukin-1 - genetics | Immunologic Memory - drug effects | Receptors, Prostaglandin E - genetics | Interleukin-23 - genetics | Receptors, Prostaglandin E, EP4 Subtype | T-Lymphocytes, Helper-Inducer - drug effects | Receptors, CCR6 - metabolism | T-Lymphocytes, Helper-Inducer - cytology | Cyclic AMP - metabolism | Dinoprostone - pharmacology | Interleukin-17 - biosynthesis | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Models, Immunological | Animals | Interleukin-23 - pharmacology | Signal Transduction - drug effects | Cell Differentiation - drug effects | Receptors, Prostaglandin E, EP2 Subtype | Interleukin-10 - biosynthesis | Mice | Interferon-gamma - biosynthesis | Receptors, Prostaglandin E - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text E-type prostanoid receptor 4 (EP4) in disease and therapy
by Konya, Viktoria and Marsche, Gunther and Schuligoi, Rufina and Heinemann, Akos
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 06/2013, Volume 138, Issue 3, pp. 485 - 502
Vascular disease | Osteoporosis | Prostaglandins | Inflammation | Renal function | Cancerogenesis | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Osteoporosis. Osteomalacia. Paget disease | Biological and medical sciences | Medical sciences | Diseases of the osteoarticular system | Neoplasms - metabolism | Receptors, Prostaglandin E, EP4 Subtype - agonists | Lung Diseases - metabolism | Cardiovascular Diseases - metabolism | Humans | Bone Diseases - metabolism | Dinoprostone - metabolism | Animals | Gastrointestinal Diseases - metabolism | Receptors, Prostaglandin E, EP4 Subtype - antagonists & inhibitors | Immunologic Factors - metabolism | Kidney Diseases - metabolism | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Index Medicus | CREB, cAMP-response element-binding protein | Associate editor | TX, thromboxane receptor | EPRAP, EP4 receptor-associated protein | PK, protein kinase | COX, cyclooxygenase | AMPK, AMP-activated protein kinase | ICAM-1, intercellular adhesion molecule-1 | PI3K, phosphatidyl insositol 3-kinase | CFTR, cystic fibrosis transmembrane conductance regulator | IP, I-type prostanoid receptor | Epac, exchange protein activated by cAMP | NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells | NSAID, non-steroidal anti-inflammatory drug | IFN, interferon | MEK, MAP kinase kinase | PG, prostaglandin | DSS, dextran sodium sulfate | eNOS, endothelial nitric oxide synthase | Ig, immunoglobulin | P. Holzer | ICER, inducible cAMP early repressor | EGFR, epidermal growth factor receptor | FEM1a, feminization 1 homolog a | ERK, extracellular signal-regulated kinase | MCP, monocyte chemoattractant protein | 5-HETE, 5-hydroxyeicosatetraenoic acid | IL, interleukin | GRK, G protein-coupled receptor kinase | MAP, mitogen-activated protein kinase | LPS, lipopolysaccharide | ClC, chloride channel | DP, D-type prostanoid receptor | FP, F-type prostanoid receptor | TP, T-type prostanoid receptor | cAMP, cyclic adenylyl monophosphate | EP, E-type prostanoid receptor
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights