X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3973) 3973
Book Review (862) 862
Publication (730) 730
Book Chapter (28) 28
Conference Proceeding (18) 18
Book / eBook (9) 9
Dissertation (6) 6
Magazine Article (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3591) 3591
animals (2813) 2813
humans (2010) 2010
mice (1199) 1199
atp (1014) 1014
neurosciences (997) 997
rats (889) 889
male (869) 869
adenosine triphosphate - metabolism (834) 834
adenosine triphosphate - pharmacology (777) 777
receptors, purinergic p2x7 - metabolism (760) 760
receptors, purinergic p2 - metabolism (739) 739
receptors, purinergic p2x7 (686) 686
cell biology (682) 682
cells, cultured (678) 678
p2x receptor (668) 668
inflammation (617) 617
activation (613) 613
extracellular atp (575) 575
biochemistry & molecular biology (532) 532
female (514) 514
signal transduction (512) 512
immunology (507) 507
calcium - metabolism (495) 495
expression (471) 471
mice, inbred c57bl (466) 466
adenosine triphosphate - analogs & derivatives (418) 418
physiological aspects (403) 403
apoptosis (394) 394
cell line (393) 393
p2x7 receptor (392) 392
p2x receptors (387) 387
rodents (384) 384
cells (376) 376
physiology (373) 373
article (365) 365
pharmacology & pharmacy (362) 362
receptors (362) 362
purinergic receptors (347) 347
receptors, purinergic p2x7 - genetics (347) 347
proteins (345) 345
rats, sprague-dawley (342) 342
receptor (339) 339
adenosine (338) 338
receptors, purinergic p2 - genetics (335) 335
mice, knockout (334) 334
neurons (328) 328
research (323) 323
p2x (319) 319
analysis (313) 313
biomedicine (313) 313
receptors, purinergic p2 - physiology (305) 305
disease models, animal (296) 296
gene expression (296) 296
release (293) 293
microglia (286) 286
adenosine triphosphate (271) 271
macrophages (271) 271
research article (268) 268
cytokines (260) 260
calcium (259) 259
multidisciplinary sciences (258) 258
purinergic p2x receptor antagonists - pharmacology (255) 255
brain (251) 251
dose-response relationship, drug (248) 248
neurons - metabolism (242) 242
immunohistochemistry (237) 237
signal transduction - physiology (235) 235
medicine (231) 231
health aspects (222) 222
microglia - metabolism (221) 221
nucleotides (218) 218
neuropathic pain (217) 217
signal transduction - drug effects (217) 217
rats, wistar (215) 215
atp release (213) 213
science (212) 212
review (210) 210
neurology (209) 209
purinergic p2 receptor antagonists (206) 206
human physiology (203) 203
cell death (202) 202
interleukin-1beta - metabolism (192) 192
pharmacology/toxicology (192) 192
macrophages - metabolism (186) 186
central-nervous-system (184) 184
rna, messenger - metabolism (184) 184
blotting, western (182) 182
p2x7 (181) 181
original (180) 180
biology (178) 178
patch-clamp techniques (177) 177
cell line, tumor (176) 176
in-vivo (176) 176
time factors (176) 176
cancer research (174) 174
astrocytes - metabolism (169) 169
astrocytes (167) 167
pain (166) 166
purinergic receptor (165) 165
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3966) 3966
Chinese (15) 15
Japanese (7) 7
Spanish (4) 4
Russian (3) 3
French (2) 2
German (2) 2
Czech (1) 1
Hungarian (1) 1
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Medicine, ISSN 1078-8956, 04/2012, Volume 18, Issue 4, pp. 600 - 604
Inflammatory bowel diseases (IBDs) are chronic relapsing and remitting conditions associated with long-term gut dysfunction resulting from alterations to the... 
MEDICINE, RESEARCH & EXPERIMENTAL | STIMULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNERVATION | RELEASE | CELL BIOLOGY | RECOVERY | INHIBITION | P2X RECEPTORS | MYENTERIC NEURONS | GLIA | ATP | MOTILITY | Myenteric Plexus - pathology | Calcium - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Gastrointestinal Motility - drug effects | Colitis - pathology | Male | Glial Fibrillary Acidic Protein - metabolism | Cytoskeletal Proteins - deficiency | Adenosine Triphosphate - pharmacology | Dose-Response Relationship, Drug | Caspases - metabolism | Time Factors | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Cytoskeletal Proteins - metabolism | Neurons - metabolism | Cell Death - drug effects | Dinitrofluorobenzene - analogs & derivatives | Neurons - drug effects | Disease Models, Animal | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Gastrointestinal Motility - genetics | Phosphodiesterase Inhibitors - pharmacology | Purinergic P2X Receptor Agonists - pharmacology | Adenosine Triphosphate - analogs & derivatives | Connexins - metabolism | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Apoptosis Regulatory Proteins | Dinitrofluorobenzene - pharmacology | Analysis of Variance | Cell Death - physiology | Signal Transduction - drug effects | CARD Signaling Adaptor Proteins | Nitric Oxide Synthase Type I - metabolism | Receptors, Purinergic P2X7 - metabolism | Mice | Neural receptors | Neurons | Physiological aspects | Development and progression | Genetic aspects | Research | Colitis | Inflammatory bowel disease | Nervous system | Gene expression | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 8, pp. 3557 - 3566
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2015, Volume 29, Issue 6, pp. 2450 - 2461
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1616 - 1628
Prolonged seizures [status epilepticus (SE)] constitute a neurological emergency that can permanently damage the brain. SE results from a failure of the normal... 
Pharmacoresistance | Temporal lobe epilepsy | Anticonvulsant | ATP | EXTRACELLULAR ATP | temporal lobe epilepsy | MICROGLIAL ACTIVATION | TEMPORAL-LOBE EPILEPSY | GLUTAMATE RELEASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFICIENT MICE | CELL BIOLOGY | pharmacoresistance | P2X RECEPTOR | BIOLOGY | CENTRAL-NERVOUS-SYSTEM | RAT HIPPOCAMPUS | SYNAPTIC TERMINALS | C-FOS EXPRESSION | Lorazepam - pharmacology | Neuroprotective Agents - therapeutic use | Microglia - metabolism | Seizures - prevention & control | Seizures - drug therapy | Status Epilepticus - chemically induced | Status Epilepticus - drug therapy | Male | Neurons - cytology | Purinergic P2X Receptor Antagonists - pharmacology | Anticonvulsants - pharmacology | Receptors, Purinergic P2X7 - genetics | Seizures - chemically induced | Lorazepam - therapeutic use | Seizures - physiopathology | Neuroprotective Agents - pharmacology | Seizures - pathology | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Neurons - metabolism | Neurons - drug effects | Microglia - cytology | Glutamic Acid - pharmacology | Kainic Acid - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Status Epilepticus - pathology | Anticonvulsants - therapeutic use | Excitatory Amino Acid Agonists - pharmacology | Hippocampus - pathology | Hippocampus - cytology | Purinergic P2X Receptor Agonists - pharmacology | Mice, Knockout | Animals | Receptors, Purinergic P2X7 - metabolism | Status Epilepticus - physiopathology | Mice | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2013, Volume 170, Issue 3, pp. 624 - 640
Background and PurposeAn increasing body of evidence suggests that the purinergic receptor P2X, ligand-gated ion channel, 7 (P2X7) in the CNS may play a key... 
interleukin 1β | | neuropathic pain | purinergic | P2X7 | autoradiography | microdialysis | depression | mania | interleukin 1β (IL-1β) | NERVOUS-SYSTEM | interleukin 1 (IL-1) | BIPOLAR DISORDER | KNOCKOUT MICE | ARRIVE GUIDELINES | P2RX7 GENE | P2X RECEPTOR | ANIMAL-MODELS | ION-CHANNEL | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | Niacinamide - analogs & derivatives | Analgesics - pharmacology | Bipolar Disorder - metabolism | Capillary Permeability | Receptors, Purinergic P2X7 - drug effects | Humans | Neuralgia - metabolism | Analgesics - metabolism | Male | Piperazines - metabolism | Purinergic P2X Receptor Antagonists - pharmacology | Adenosine Triphosphate - pharmacology | Brain - metabolism | Dose-Response Relationship, Drug | Depression - metabolism | Transfection | Neuralgia - prevention & control | Time Factors | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Behavior, Animal - drug effects | Neuralgia - psychology | Antidepressive Agents - pharmacology | Macaca | Disease Models, Animal | Binding, Competitive | Cell Line | Antimanic Agents - pharmacology | Niacinamide - metabolism | Mice, Inbred C57BL | Rats | Piperazines - pharmacology | Rats, Sprague-Dawley | Adenosine Triphosphate - analogs & derivatives | Bipolar Disorder - psychology | Blood-Brain Barrier - metabolism | Brain - drug effects | Animals | Depression - prevention & control | Calcium Signaling - drug effects | Dogs | Depression - psychology | Protein Binding | Purinergic P2X Receptor Antagonists - metabolism | Receptors, Purinergic P2X7 - metabolism | Mice | Niacinamide - pharmacology | Bipolar Disorder - prevention & control | Chemical properties | Depression, Mental | Analysis | Chronic pain | Index Medicus | Research Papers
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2017, Volume 138, pp. 130 - 139
Diabetic retinopathy (DR) is the most frequent complication of diabetes and one of leading causes of blindness worldwide. Early phases of DR are characterized... 
Pericytes | Diabetic retinopathy | Inflammation | IL-1β | P2X7 receptor | Molecular modeling | MOLECULAR-DYNAMICS | ACTIVATION | MECHANISM | IL-1 beta | RELEASE | ASTROCYTES | ATP-BINDING | NETWORK ANALYSIS | IN-VITRO | PHARMACOLOGY & PHARMACY | BINDING-SITES | P2X-INDUCED PORE FORMATION | Niacinamide - analogs & derivatives | Diabetic Retinopathy - drug therapy | Pericytes - drug effects | Purinergic P2X Receptor Antagonists - pharmacokinetics | Apoptosis - drug effects | Expert Systems | Humans | Molecular Conformation | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Piperazines - metabolism | Purinergic P2X Receptor Antagonists - pharmacology | Piperazines - chemistry | Diabetic Retinopathy - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Niacinamide - chemistry | Pericytes - pathology | Databases, Protein | Niacinamide - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Piperazines - pharmacokinetics | Biomarkers - metabolism | Diabetic Retinopathy - immunology | Niacinamide - metabolism | Allosteric Site - drug effects | Pericytes - metabolism | Cells, Cultured | Computational Biology | Models, Molecular | Piperazines - pharmacology | Diabetic Retinopathy - metabolism | Pericytes - immunology | Animals | Databases, Chemical | Purinergic P2X Receptor Antagonists - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Purinergic P2X Receptor Antagonists - metabolism | Receptors, Purinergic P2X7 - metabolism | Ligands | ROC Curve | Molecular Docking Simulation | Structural Homology, Protein | Niacinamide - pharmacology | Receptors, Purinergic P2X7 - chemistry | Medical colleges | Analysis | Blindness | Physiological aspects | Glucose | Dextrose | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2011, Volume 286, Issue 4, pp. 2596 - 2606
The amyloid precursor protein (APP) is cleaved by beta- and gamma-secretases to generate the beta-amyloid (A beta) peptides, which are present in large amounts... 
EXTRACELLULAR ATP | ALZHEIMER-DISEASE | TUMOR-NECROSIS-FACTOR | L-SELECTIN | P2X RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPID RAFTS | MOUSE MODEL | RELEASE | MICE LACKING | CELL-DEATH | Amyloid Precursor Protein Secretases - genetics | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Stem Cells - metabolism | Receptors, Purinergic P2X7 - genetics | Gene Knockdown Techniques | Protease Inhibitors - pharmacology | MAP Kinase Kinase 4 - metabolism | Mice, Mutant Strains | Amyloid beta-Protein Precursor - metabolism | MAP Kinase Kinase 4 - antagonists & inhibitors | Neurons - metabolism | Hydroxamic Acids - pharmacology | Protein Structure, Tertiary | ADAM Proteins - antagonists & inhibitors | Mitogen-Activated Protein Kinase 3 - genetics | Dipeptides - pharmacology | Alzheimer Disease - drug therapy | Hippocampus - metabolism | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Alzheimer Disease - metabolism | Cell Line, Tumor | MAP Kinase Kinase 4 - genetics | Receptors, Purinergic P2X7 - metabolism | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | ADAM Proteins - genetics | Alzheimer Disease - genetics | Astrocytes - metabolism | Index Medicus | MAP Kinases (MAPKs) | Purinergic Receptor | Secretases | Alzheimer Disease | ATP | Cell Biology
Journal Article
Journal Article