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Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2012, Volume 366, Issue 7, pp. 610 - 618
Journal Article
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 2007, Volume 21, Issue 8, pp. 1658 - 1668
JAK2V617F and MPLW515L/K represent recently identified mutations in myeloproliferative disorders (MPD) that cause dysregulated JAK-STAT signaling, which is... 
MYELOFIBROSIS | JAK2(V617F) | POLYCYTHEMIA-VERA | ESSENTIAL THROMBOCYTHEMIA | JAK2V617F | myeloproliferative disorder | mutation | kinase inhibitor | MEGAKARYOBLASTIC LEUKEMIA | ACTIVATING MUTATION | ONCOLOGY | V617F | ACUTE LYMPHOBLASTIC-LEUKEMIA | JAK2 | HEMATOLOGY | MYELOID METAPLASIA | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Apoptosis - drug effects | Humans | STAT Transcription Factors - metabolism | Polycythemia Vera - genetics | Myeloproliferative Disorders - genetics | Janus Kinase 3 - antagonists & inhibitors | Polycythemia Vera - metabolism | fms-Like Tyrosine Kinase 3 - genetics | Janus Kinase 2 - metabolism | Myeloproliferative Disorders - metabolism | Colony-Forming Units Assay | Phosphorylation - drug effects | Janus Kinase 3 - metabolism | Janus Kinase 2 - antagonists & inhibitors | Primary Myelofibrosis - metabolism | Primary Myelofibrosis - drug therapy | Thrombopoietin - metabolism | Enzyme Inhibitors - pharmacology | Janus Kinase 2 - genetics | Myeloproliferative Disorders - drug therapy | Pyrimidines - pharmacology | Mice, SCID | Mutation - genetics | Sulfonamides - pharmacology | Receptors, Thrombopoietin - metabolism | Receptors, Thrombopoietin - antagonists & inhibitors | fms-Like Tyrosine Kinase 3 - metabolism | Receptors, Thrombopoietin - genetics | Primary Myelofibrosis - genetics | Animals | Janus Kinase 3 - genetics | Stem Cells - drug effects | Polycythemia Vera - drug therapy | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Antibody diversity | Chemical inhibitors | Genetic aspects | Research | Health aspects | Myeloproliferative disorders
Journal Article
Leukemia, ISSN 0887-6924, 03/2016, Volume 30, Issue 3, pp. 536 - 544
Thrombocytopenia is commonly seen in myelodysplastic syndrome (MDS) patients, and bleeding complications are a major cause of morbidity and mortality.... 
ONCOLOGY | PHASE-III | HEMATOPOIETIC SUPPRESSION | MYELOGENOUS LEUKEMIA | DOUBLE-BLIND | RISK MYELODYSPLASTIC SYNDROME | ACUTE MYELOID-LEUKEMIA | RANDOMIZED CONTROLLED-TRIAL | THROMBOPOIETIN | HEMATOLOGY | BONE-MARROW FAILURE | CELL-DEATH | Blood Platelets - pathology | Thrombocytopenia - epidemiology | Pyrazoles - therapeutic use | Benzoates - therapeutic use | Prognosis | Humans | Recombinant Fusion Proteins - therapeutic use | Gene Expression Regulation, Neoplastic | Thrombopoietin - therapeutic use | Antineoplastic Agents - therapeutic use | Thrombocytopenia - complications | Receptors, Fc - therapeutic use | Myelodysplastic Syndromes - therapy | Cell Differentiation | Thrombocytopenia - therapy | Blood Platelets - drug effects | Megakaryocytes - metabolism | Hydrazines - therapeutic use | Thrombopoietin - metabolism | Hemorrhage - epidemiology | Signal Transduction | Hemorrhage - therapy | Platelet Transfusion | Hemorrhage - complications | Myelodysplastic Syndromes - epidemiology | Myelodysplastic Syndromes - complications | Receptors, Thrombopoietin - metabolism | Receptors, Thrombopoietin - antagonists & inhibitors | Hemorrhage - diagnosis | Receptors, Thrombopoietin - genetics | Thrombopoietin - genetics | Megakaryocytes - pathology | Myelodysplastic Syndromes - diagnosis | Blood Platelets - metabolism | Thrombocytopenia - diagnosis | Megakaryocytes - drug effects | Thrombocytopenia | Complications and side effects | Care and treatment | Chemotherapy | Leukemia | Development and progression | Cellular signal transduction | Research | Health aspects | Risk factors | Cancer
Journal Article
American Journal of Hematology, ISSN 0361-8609, 07/2012, Volume 87, Issue 7, pp. 743 - 745
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0151088 - e0151088
Journal Article
Journal Article