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Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Index Medicus | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
Journal Article
2015, Transformations: studies in the history of science and technology, ISBN 9780262028660, xii, 336
In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping... 
HIV Infections | Patents | genetics | Genetic genealogy | Genes | Acquired Immunodeficiency Syndrome | Receptors, CCR5 | Continental Population Groups | HIV (Viruses) | Human population genetics | Patents as Topic | HIV infections | Clinical & internal medicine | Health Sciences | Genetics - Patents | Medical sciences | Pharmaceutical industry | Chemokines | Intellectual property
Book
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 420 - 428
Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans, but currently do not transmit efficiently among humans. The viral haemagglutinin... 
SINGLE AMINO-ACID | MEMBRANE-FUSION | IN-VITRO | AVIAN H5N1 | HEMAGGLUTININ | A VIRUSES | MULTIDISCIPLINARY SCIENCES | SIALIC-ACID | RECEPTOR-BINDING SPECIFICITY | MOLECULAR-BASIS | SWINE-ORIGIN H1N1 | Pandemics | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Receptors, Virus - metabolism | Humans | Influenza A Virus, H1N1 Subtype - physiology | Reassortant Viruses - genetics | Reassortant Viruses - physiology | Influenza A Virus, H5N1 Subtype - genetics | Body Fluids - virology | Molecular Epidemiology - methods | Ferrets - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zoonoses - virology | Respiratory System - virology | Adaptation, Physiological - genetics | HEK293 Cells | Female | Influenza, Human - virology | Protein Stability | Influenza A Virus, H1N1 Subtype - genetics | Population Surveillance - methods | Cell Line | Security Measures | Birds - virology | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza in Birds - transmission | Hot Temperature | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Reassortant Viruses - isolation & purification | Respiratory System - anatomy & histology | Zoonoses - transmission | Animals | Receptors, Virus - chemistry | Orthomyxoviridae Infections - transmission | Dogs | Influenza in Birds - virology | Bioterrorism - prevention & control | Influenza A Virus, H5N1 Subtype - pathogenicity | HeLa Cells | Influenza, Human - prevention & control | Orthomyxoviridae Infections - virology | Evolution, Molecular | Prevention | Epidemics | Disease transmission | United States | Japan | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Host-virus relationships | Ferrets | Cell culture | Task forces | Compliance | Laboratories | RNA polymerase | Academic libraries | Experiments | Avian flu | Proteins | Studies | Swine flu | Plasmids | Risk assessment | Occupational health | Mutation | Index Medicus
Journal Article
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1534 - 1541
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by... 
Receptors | Inoculation | Experimental infection | Disease transmission | Pandemics | REPORTS | Viruses | Orthomyxoviridae | Ferrets | Genetic mutation | Amino acid substitution | A VIRUS | TO-PERSON TRANSMISSION | MEDIATED SELECTION | H5N1 VIRUS | HEMAGGLUTININ | MULTIDISCIPLINARY SCIENCES | HOST | INFECTION | MODEL | RECEPTOR SPECIFICITY | PATHOGENIC AVIAN INFLUENZA | Immune Sera | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Poultry | Receptors, Virus - metabolism | Air Microbiology | Humans | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Female | Influenza, Human - virology | Oseltamivir - pharmacology | Disease Models, Animal | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Antiviral Agents - pharmacology | Mutagenesis, Site-Directed | RNA Replicase - genetics | Viral Proteins - chemistry | Sialic Acids - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Containment of Biohazards | Influenza A Virus, H5N1 Subtype - drug effects | Influenza in Birds - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | RNA Replicase - chemistry | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Mutation | Serial Passage | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Avian influenza | Diseases and pests | Physiological aspects | Development and progression | Research | Animal diseases | Amino acids | Avian flu | Small mammals | Index Medicus | Polymerase | Human | Proteins | Influenza | Droplets | Genetic modification
Journal Article
eLife, ISSN 2050-084X, 11/2012, Volume 2012, Issue 1, pp. e00049 - e00049
Human hepatitis B virus (HBV) infection and HBV-related diseases remain a major public health problem. Individuals coinfected with its satellite hepatitis D... 
viruses | receptor | Sodium taurocholate cotransporting polypeptide | hepatitis D virus | infectious disease | liver | hepatitis B virus | biochemistry | microbiology | virus infection | CLOSED CIRCULAR DNA | IN-VITRO | HEPATOCELLULAR-CARCINOMA | DELTA-VIRUS | TUPAIA HEPATOCYTES | RAT HEPATOCYTES | ADULT HUMAN HEPATOCYTES | BIOLOGY | PRE-S SEQUENCE | LARGE SURFACE PROTEIN | ENVELOPE PROTEINS | Liver - virology | Liver - pathology | Receptors, Virus - metabolism | Taurocholic Acid - metabolism | Humans | Hepatitis Delta Virus - metabolism | Molecular Sequence Data | Hepatocytes - pathology | Hepatocytes - metabolism | Receptors, Virus - genetics | Virus Internalization | Organic Anion Transporters, Sodium-Dependent - genetics | Photochemical Processes | Organic Anion Transporters, Sodium-Dependent - chemistry | Biological Transport | Hepatitis B virus - chemistry | Tupaia | Viral Envelope Proteins - metabolism | Hepatitis Delta Virus - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Gene Expression | Viral Envelope Proteins - genetics | Peptides - chemistry | Liver - metabolism | Symporters - chemistry | Symporters - metabolism | Animals | Hepatitis Delta Virus - chemistry | Receptors, Virus - chemistry | Symporters - genetics | Viral Envelope Proteins - chemistry | Hepatitis B virus - genetics | Hepatocytes - virology | Protein Binding | Hepatitis B virus - metabolism | Primary Cell Culture | Organic Anion Transporters, Sodium-Dependent - metabolism | Antigens | Polypeptides | Liver | Envelope protein | Amino acids | Viruses | Infections | Genomes | Proteins | Hepatitis | Sodium | Rodents | Public health | Viral infections | Hepatitis B | Index Medicus
Journal Article
Glycoconjugate Journal, ISSN 0282-0080, 2/2006, Volume 23, Issue 1, pp. 101 - 106
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 27, pp. 4469 - 4475
Abstract Current vaccine candidates against Rift Valley fever virus (RVFV) incorporate the viral structural glycoproteins as antigens, since triggering...