X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (137447) 137447
Publication (18560) 18560
Book Review (1229) 1229
Book Chapter (184) 184
Book / eBook (164) 164
Dissertation (74) 74
Conference Proceeding (72) 72
Newsletter (19) 19
Reference (19) 19
Data Set (13) 13
Magazine Article (8) 8
Paper (4) 4
Web Resource (2) 2
Government Document (1) 1
Newspaper Article (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (116747) 116747
animals (91517) 91517
male (51182) 51182
rats (45221) 45221
humans (37239) 37239
neurosciences (34875) 34875
mice (34556) 34556
female (24346) 24346
pharmacology & pharmacy (23950) 23950
rats, sprague-dawley (17562) 17562
receptors (15818) 15818
dose-response relationship, drug (15750) 15750
biochemistry & molecular biology (15736) 15736
expression (15456) 15456
cells, cultured (15218) 15218
cell biology (14837) 14837
activation (14094) 14094
physiology (13017) 13017
rodents (12914) 12914
receptor (12349) 12349
rats, wistar (11956) 11956
proteins (11575) 11575
article (11382) 11382
analysis (11105) 11105
mice, inbred c57bl (10948) 10948
brain (10864) 10864
signal transduction (10864) 10864
neurons (10618) 10618
gene expression (10120) 10120
physiological aspects (10013) 10013
in vitro techniques (9694) 9694
endocrinology & metabolism (9527) 9527
inflammation (9441) 9441
research (9388) 9388
immunology (8986) 8986
cells (8805) 8805
rat (8555) 8555
multidisciplinary sciences (8506) 8506
cell line (8341) 8341
research article (8057) 8057
disease models, animal (7957) 7957
phosphorylation (7760) 7760
ligands (7630) 7630
apoptosis (7465) 7465
medicine (7251) 7251
time factors (6992) 6992
in-vitro (6793) 6793
inhibition (6622) 6622
calcium - metabolism (6546) 6546
mice, knockout (6440) 6440
neurons - drug effects (6381) 6381
gene-expression (6364) 6364
neurology (6306) 6306
signal transduction - drug effects (6277) 6277
cell line, tumor (6124) 6124
science (6030) 6030
immunohistochemistry (5764) 5764
in-vivo (5704) 5704
kinases (5545) 5545
dopamine (5520) 5520
rna, messenger - metabolism (5327) 5327
neurons - metabolism (5211) 5211
biomedicine (5190) 5190
biology (5121) 5121
glutamate (5107) 5107
health aspects (5100) 5100
cytokines (4981) 4981
psychiatry (4952) 4952
calcium (4820) 4820
abridged index medicus (4796) 4796
pharmacology (4781) 4781
binding (4772) 4772
oncology (4739) 4739
nervous system (4722) 4722
cancer (4545) 4545
adult (4458) 4458
kinetics (4379) 4379
biochemistry (4366) 4366
medicine, research & experimental (4359) 4359
hippocampus (4240) 4240
blotting, western (4166) 4166
metabolism (4135) 4135
gaba (4098) 4098
brain - metabolism (4072) 4072
serotonin (4066) 4066
toxicology (4064) 4064
rat-brain (3996) 3996
genetic aspects (3958) 3958
biophysics (3908) 3908
protein binding (3851) 3851
enzyme inhibitors - pharmacology (3847) 3847
peptides (3847) 3847
mechanisms (3834) 3834
messenger-rna (3789) 3789
oxidative stress (3741) 3741
middle aged (3723) 3723
reverse transcriptase polymerase chain reaction (3669) 3669
patch-clamp techniques (3662) 3662
release (3655) 3655
behavior, animal - drug effects (3563) 3563
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (129) 129
Online Resources - Online (7) 7
Collection Dvlpm't (Acquisitions) - Closed Orders (6) 6
UofT at Mississauga - Stacks (4) 4
UofT at Scarborough - Stacks (4) 4
Collection Dvlpm't (Acquisitions) - Vendor file (2) 2
UTL at Downsview - May be requested (2) 2
Chemistry (A D Allen) - Stacks (1) 1
Dentistry (Harry R Abbott) - Stacks (1) 1
Gerstein Science - Periodical Stacks (1) 1
Providence Healthcare - Reference (1) 1
Providence Healthcare - Stacks (1) 1
St. Michael's Hospital - Stacks (1) 1
Toronto East General Hospital - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (137656) 137656
Russian (27) 27
German (25) 25
Japanese (23) 23
French (18) 18
Spanish (11) 11
Chinese (7) 7
Polish (3) 3
Arabic (2) 2
Afrikaans (1) 1
Czech (1) 1
Hebrew (1) 1
Italian (1) 1
Korean (1) 1
Portuguese (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 01/2017, Volume 125, pp. 603 - 610
cis-N-Substituted N-normetazocine enantiomers possess peculiar pharmacological profiles. Indeed, dextro enantiomers bind with high affinity cri receptor while... 
CHEMISTRY, MEDICINAL | MORPHINE | Mechanical antinociception | Opioid | (-)-Phenazocine | SIGMA RECEPTOR | Sigma-1 receptor | GUINEA-PIG BRAIN | (+)-Phenazocine | PAIN | LIGANDS | AFFINITY | Bifunctional ligand | BINDING | MODULATION | ANALGESIA | AGONIST
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 10/2013, Volume 347, Issue 1, pp. 20 - 29
A previous study showed that cocaine self-administration induced dopamine-independent reinforcing effects of sigma agonists mediated by their selective actions... 
ACTIVATION | RHESUS-MONKEYS | CONDITIONED PLACE PREFERENCE | RECEPTOR AGONISTS | DISCRIMINATING COCAINE | PROTEIN EXPRESSION | REINFORCEMENT | PHARMACOLOGY & PHARMACY | BRAIN | NUCLEUS-ACCUMBENS | UPTAKE INHIBITORS
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2011, Volume 69, Issue 3, pp. 208 - 217
Journal Article
Synapse, ISSN 0887-4476, 04/2015, Volume 69, Issue 4, pp. 213 - 225
Journal Article
Journal Article
British Journal of Ophthalmology, ISSN 0007-1161, 10/2007, Volume 91, Issue 10, pp. 1382 - 1384
Journal Article
Biochemistry, ISSN 0006-2960, 05/2014, Volume 53, Issue 18, pp. 2993 - 3003
The σ1 receptor is an integral membrane protein that shares no homology with other receptor systems, has no unequivocally identified natural ligands, but... 
Mutagenesis, Site-Directed | Computer Simulation | Models, Molecular | Ligands | Receptors, sigma - agonists | Receptors, sigma - metabolism | Binding Sites | Molecular Dynamics Simulation | Pentazocine - metabolism | Index Medicus
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 07/2016, Volume 24, Issue 14, pp. 3149 - 3156
We previously reported bifunctional sigma-1 (sigma(1)) ligands endowed with antioxidant activity (1 and 2). In the present paper, pure enantiomers (R)-1 and... 
Oxidative stress | Neuroprotection | Lipoic acid | CHEMISTRY, MEDICINAL | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | RATS | CHEMISTRY, ORGANIC | KAPPA-B | SUPPRESSION | SELECTIVE CHOLINERGIC LESION | sigma receptors | Antioxidants | Chemical and enzymatic stabilities | SIGMA-1 RECEPTOR | BINDING | MODULATION
Journal Article