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Biotechnology and Bioengineering, ISSN 0006-3592, 11/2014, Volume 111, Issue 11, pp. 2317 - 2325
ABSTRACT Mucopolysaccharidosis (MPS) Type II is caused by mutations in the gene encoding the lysosomal enzyme, iduronate 2‐sulfatase (IDS). The majority of... 
blood‐brain barrier | drug delivery | monoclonal antibody | lysosomal enzyme | Lysosomal enzyme | Drug delivery | Monoclonal antibody | Blood-brain barrier | blood-brain barrier | MONOCLONAL-ANTIBODY | II HUNTER-SYNDROME | IDURONATE-2-SULFATASE | IDURSULFASE | BLOOD-BRAIN-BARRIER | DELIVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | TRANSCYTOSIS | DISEASE | IDURONIDASE | ENZYME REPLACEMENT THERAPY | Glycoproteins - genetics | Antigens, CD - immunology | Recombinant Fusion Proteins - adverse effects | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - pharmacokinetics | Glycoproteins - adverse effects | Metabolic Clearance Rate | Macaca mulatta | Glycoproteins - administration & dosage | Drug-Related Side Effects and Adverse Reactions - epidemiology | Drug-Related Side Effects and Adverse Reactions - pathology | Antibodies, Monoclonal - genetics | Animals | Antibodies, Monoclonal - administration & dosage | Plasma - chemistry | Recombinant Fusion Proteins - pharmacokinetics | Recombinant Fusion Proteins - genetics | Glycoproteins - pharmacokinetics | Infusions, Intravenous | Receptor, Insulin - immunology | Recombinant Fusion Proteins - administration & dosage | Viral antibodies | Safety and security measures | Antibodies | Pharmacology | Insulin | Biopharmaceutics | Diabetes therapy | Proteins | Brain | Enzymes | Receptors | Monkeys | Transport
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 24, pp. 2313 - 2323
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 38, pp. 16432 - 16437
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Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 6, pp. 1237 - 1244.e2
Journal Article
Journal Article