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Immunotechnology, ISSN 1380-2933, 1995
Journal
Microbial biotechnology, ISSN 1751-7915, 2016, Volume 9, Issue 3, pp. 355 - 368
...) in the yeast Pichia pastoris; this membrane protein is responsible for the synthesis of rabies neutralizing antibodies... 
HETEROLOGOUS PROTEIN EXPRESSION | YEAST | SYSTEM | SECRETORY EXPRESSION | OVEREXPRESSION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE DOSAGE | PHYSIOLOGICAL-RESPONSE | MICROBIOLOGY | ENDOPLASMIC-RETICULUM | STRESS | INSULIN PRECURSOR | Metabolic Engineering | Glycoproteins - metabolism | Antigens, Viral - genetics | Neutralization Tests | Recombinant Proteins - biosynthesis | Antibodies, Neutralizing - immunology | Pichia - metabolism | Codon | Viral Envelope Proteins - metabolism | Antigens, Viral - biosynthesis | Glycoproteins - genetics | Recombinant Proteins - metabolism | Gene Expression | Viral Envelope Proteins - genetics | Viral Envelope Proteins - biosynthesis | Gene Dosage | Recombinant Proteins - genetics | Unfolded Protein Response | Protein Folding | Glycoproteins - biosynthesis | Antigens, Viral - immunology | Glycoproteins - immunology | Recombinant Proteins - immunology | Pichia - genetics | Viral Envelope Proteins - immunology | Pichia - growth & development | Yeasts | Baking yeast | Yeast | Copy number | Secretion | Antibodies | Viruses | Glycoproteins | Gene expression | Optimization | Membrane proteins | Proteins | Protein folding | Rabies | Neutralizing | Protein expression | Acid phosphatase | Folding | Viral Envelope Proteins/genetics | Viral Envelope Proteins/immunology | Glycoproteins/immunology | Antigens, Viral/biosynthesis | Recombinant Proteins/immunology | Pichia/growth & development | Antigens, Viral/genetics | Recombinant Proteins/metabolism | Life Sciences | Viral Envelope Proteins/metabolism | Viral Envelope Proteins/biosynthesis | Glycoproteins/biosynthesis | Antibodies, Neutralizing/immunology | Antigens, Viral/immunology | Glycoproteins/metabolism | Recombinant Proteins/biosynthesis | Recombinant Proteins/genetics | Pichia/genetics | Glycoproteins/genetics | Pichia/metabolism
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 1844 - 12
Lentiviruses have evolved to acquire an auxiliary protein Vpx to counteract the intrinsic host restriction factor SAMHD1... 
COMPLEX | REPLICATION | INTEGRATION | STRUCTURAL BASIS | PROTEIN-SYNTHESIS SYSTEM | MULTIDISCIPLINARY SCIENCES | INHIBITORS | HIV-1 INFECTION | CELL | EXPRESSION | IMMUNODEFICIENCY-VIRUS VPX | Humans | Proto-Oncogene Proteins c-pim-1 - metabolism | Pyridazines - pharmacology | Proto-Oncogene Proteins c-pim-1 - immunology | Host-Pathogen Interactions - immunology | Recombinant Proteins - isolation & purification | HIV Infections - immunology | Proteolysis - drug effects | Biphenyl Compounds - pharmacology | Protein Processing, Post-Translational - drug effects | SAM Domain and HD Domain-Containing Protein 1 - immunology | Proto-Oncogene Proteins c-pim-1 - antagonists & inhibitors | Protein Binding - drug effects | HEK293 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - immunology | Phosphorylation - immunology | Protein Processing, Post-Translational - immunology | Thiazolidines - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Viral Regulatory and Accessory Proteins - isolation & purification | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Virus Replication - drug effects | SAM Domain and HD Domain-Containing Protein 1 - metabolism | HIV Infections - virology | Immune Tolerance | Virus Replication - immunology | Imidazoles - pharmacology | Protein Binding - immunology | Serine - metabolism | Molecular Dynamics Simulation | Viral Regulatory and Accessory Proteins - metabolism | SAM Domain and HD Domain-Containing Protein 1 - chemistry | Monocytes | Protein Kinase Inhibitors - therapeutic use | HIV-2 - immunology | Proteomics | Cell Line, Tumor | HIV Infections - drug therapy | Protein-Serine-Threonine Kinases - immunology | Protein Kinase Inhibitors - pharmacology | Viral Regulatory and Accessory Proteins - chemistry | Ubiquitin | Phosphorylation | Threonine | Serine | Viruses | Functional analysis | Promotion | Kinases | Proteins | Protein X | Restoration | Proteolysis | Human immunodeficiency virus--HIV | Infectivity | Antiviral activity | Proteasomes
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2011, Volume 286, Issue 9, pp. 7214 - 7226
The Ca2+-binding protein of the EF-hand type, S100B, is abundantly expressed in and secreted by astrocytes, and release of S100B from damaged astrocytes occurs during the course of acute and chronic brain disorders... 
CYTOPLASMIC DOMAIN | IN-VITRO | ACTIVATION | NEURITE OUTGROWTH | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NITRIC-OXIDE | RECEPTOR | GROWTH-FACTOR | RHO-GTPASES | GLYCATION END-PRODUCTS | Microglia - metabolism | Chemokine CCL3 - immunology | Nerve Growth Factors - metabolism | S100 Proteins - immunology | Cell Movement - immunology | S100 Proteins - genetics | Chemokine CXCL12 - genetics | Microglia - immunology | Chemokine CCL3 - genetics | Calcium-Binding Proteins - immunology | Cattle | Encephalitis - metabolism | Chemokine CCL3 - metabolism | Chemokine CCL5 - metabolism | Receptors, Immunologic - immunology | Receptor for Advanced Glycation End Products | Chemokine CXCL12 - immunology | Chemokines - immunology | Calcium-Binding Proteins - metabolism | Microglia - cytology | Recombinant Proteins - metabolism | Cell Line | S100 Calcium Binding Protein beta Subunit | Mice, Inbred C57BL | Rats | Encephalitis - immunology | S100 Proteins - metabolism | Nerve Growth Factors - immunology | Recombinant Proteins - genetics | Chemokines - genetics | Animals | Carrier Proteins - metabolism | Chemokine CXCL12 - metabolism | Recombinant Proteins - immunology | Up-Regulation - immunology | Nerve Growth Factors - genetics | Chemokine CCL5 - genetics | Cytoskeleton - metabolism | Chemokines - metabolism | Mice | Receptors, Immunologic - genetics | Chemokine CCL5 - immunology | Receptors, Immunologic - metabolism | Calcium-Binding Proteins - genetics | Index Medicus | Immunology | Defensins | Signal Transduction | Neurodegeneration | Migration | Calcium-binding Proteins | Innate Immunity | RAGE | S100B | Chemokines | Microglia
Journal Article
Infection and immunity, ISSN 1098-5522, 2016, Volume 84, Issue 6, pp. 1796 - 1805
.... How tick proteins regulate immune signaling, however, is incompletely understood. Here, we describe that loop 2 of sialostatin L2, an anti-inflammatory tick protein... 
SYSTEM | INFECTIOUS DISEASES | NAIP/NLRC4 INFLAMMASOMES | RECOGNITION | BORNE PATHOGENS | DOCKING | SERVER | HUMAN GRANULOCYTIC ANAPLASMOSIS | BACTERIAL LIGANDS | NEEDLE PROTEIN | ANAPLASMA-PHAGOCYTOPHILUM INFECTION | IMMUNOLOGY | Interleukin-18 - immunology | Caspases - immunology | Humans | Ixodes - chemistry | Arachnid Vectors - genetics | Interleukin-1beta - genetics | Ixodes - genetics | Calcium-Binding Proteins - immunology | Protein Isoforms - chemistry | Macrophages - microbiology | Calcium-Binding Proteins - chemistry | Amino Acid Sequence | Apoptosis Regulatory Proteins - immunology | Signal Transduction | Apoptosis Regulatory Proteins - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Arachnid Vectors - immunology | Cystatins - immunology | Annexin A2 - genetics | Immune Evasion | Cystatins - genetics | Escherichia coli - genetics | Cystatins - chemistry | Mice | Interleukin-18 - genetics | Ixodes - immunology | Calcium-Binding Proteins - genetics | Ehrlichiosis - pathology | Caspase 1 - immunology | Anaplasma phagocytophilum - genetics | Annexin A2 - chemistry | Escherichia coli - metabolism | Apoptosis Regulatory Proteins - genetics | Annexin A2 - immunology | Macrophages - immunology | Arachnid Vectors - chemistry | Ehrlichiosis - microbiology | Caspases - genetics | Gene Expression Regulation | Ehrlichiosis - immunology | Interleukin-1beta - immunology | Recombinant Proteins - genetics | Inflammasomes - genetics | Anaplasma phagocytophilum - immunology | Animals | Recombinant Proteins - immunology | Caspase 1 - genetics | Inflammasomes - immunology | Protein Binding | Protein Isoforms - immunology | Protein Isoforms - genetics
Journal Article
Nature medicine, ISSN 1546-170X, 2019, Volume 25, Issue 5, pp. 767 - 775
Anti-tumor immunity is driven by self versus non-self discrimination. Many immunotherapeutic approaches to cancer have taken advantage of tumor neoantigens... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN | TUMOR-ANTIGENS | LANDSCAPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BCR-ABL | INDUCTION | CANCER | SOMATIC MUTATIONS | CELL BIOLOGY | PEPTIDES | IMMUNOTHERAPY | BLOCKADE | Recombinant Fusion Proteins - immunology | Oncogene Proteins - genetics | Immunotherapy - methods | Humans | Proto-Oncogene Proteins c-myb - genetics | Programmed Cell Death 1 Receptor - antagonists & inhibitors | NFI Transcription Factors - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Neoplasms - therapy | Neoplasms - genetics | Nuclear Proteins - genetics | Oncogene Proteins - immunology | T-Lymphocytes, Cytotoxic - immunology | Antigens, Neoplasm - genetics | Head and Neck Neoplasms - therapy | Poly-ADP-Ribose Binding Proteins - genetics | Gene Fusion | Proto-Oncogene Proteins c-myb - immunology | Nuclear Proteins - immunology | Chromosomal Proteins, Non-Histone - genetics | Whole Genome Sequencing | Chromosomal Proteins, Non-Histone - immunology | Head and Neck Neoplasms - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Neoplasms - immunology | Recombinant Fusion Proteins - genetics | Head and Neck Neoplasms - genetics | Poly-ADP-Ribose Binding Proteins - immunology | Squamous Cell Carcinoma of Head and Neck - therapy | NFI Transcription Factors - immunology | Care and treatment | Immune response | Patient outcomes | Immunotherapy | Tumor antigens | Head and neck cancer | Genetic aspects | T cells | Identification and classification | Health aspects | Gene fusion | Antigens | Cytotoxicity | Immunosurveillance | Genomes | Lymphocytes T | Ribonucleic acid--RNA | Immunity | Metastases | Gene sequencing | Inhibitors | Immune checkpoint | Immunogenicity | Lymphocytes | Antigen (tumor-associated) | Infiltration | Mutation | Pretreatment | Tumors | Cancer | tumor-antigens | somatic mutations | bcr-abl | induction | blockade | immunotherapy | protein | peptides | cancer | Cancer and Oncology | landscape | Cancer och onkologi
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 17, pp. 5533 - 5538
...). A gene encoding a fungal PG was fused with a gene encoding a plant polygalacturonase-inhibiting protein (PGIP... 
PGIP | Polygalacturonase | Oligogalacturonides | Plant immunity | DAMPs | POLYGALACTURONASE-INHIBITING PROTEIN | ARABIDOPSIS-THALIANA | DEFENSE RESPONSES | BOTRYTIS-CINEREA | MULTIDISCIPLINARY SCIENCES | TRANSLATIONAL INHIBITION | oligogalacturonides | SALICYLIC-ACID | SIGNALING PATHWAY | ELICITORS | polygalacturonase | RESISTANCE | HOST-PATHOGEN INTERACTIONS | plant immunity | Recombinant Fusion Proteins - immunology | Plant Immunity | Fungal Proteins - biosynthesis | Pseudomonas syringae - growth & development | Plant Diseases - immunology | Polygalacturonase - immunology | Arabidopsis - immunology | Plant Diseases - microbiology | Fungal Proteins - immunology | Arabidopsis Proteins - biosynthesis | Hexuronic Acids - immunology | Plant Diseases - genetics | Polygalacturonase - genetics | Pectobacterium carotovorum - growth & development | Botrytis - immunology | Botrytis - growth & development | Pectobacterium carotovorum - immunology | Recombinant Fusion Proteins - biosynthesis | Arabidopsis Proteins - genetics | Pseudomonas syringae - immunology | Mice, Transgenic | Plant Proteins - immunology | Fungal Proteins - genetics | Arabidopsis Proteins - immunology | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis - microbiology | Plant Proteins - genetics | Polygalacturonase - biosynthesis | Animals | Recombinant Fusion Proteins - genetics | Plant Proteins - biosynthesis | Hexuronic Acids - metabolism | Enzymes | Botanical research | Pectin | Disease susceptibility | Regulation | Research | Properties | Gene expression | Observations | Biological Sciences
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2009, Volume 183, Issue 10, pp. 6469 - 6477
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice deficient in ST2, a receptor for the latest member of the IL-1 family,... 
IL-1-LIKE CYTOKINE IL-33 | IMMUNE-RESPONSE | ST2 RECEPTOR | EFFECTOR FUNCTION | MAST-CELLS | IN-VIVO | INDUCED ARTHRITIS | ALVEOLAR MACROPHAGES | INTERLEUKIN-1 RECEPTOR | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Asthma - metabolism | Epithelial Cells - metabolism | Ovalbumin - immunology | Humans | Middle Aged | Chemokine CCL24 - metabolism | Interleukin-13 - immunology | Male | Interleukins - metabolism | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Interleukins - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Interleukin-4 - genetics | Macrophages, Alveolar - immunology | Recombinant Proteins - metabolism | Cell Polarity - immunology | Lung - pathology | Receptors, Interleukin - immunology | Interleukin-33 | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Inflammation - immunology | Receptors, Interleukin-4 - immunology | Interleukin-13 - metabolism | Chemokine CCL24 - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Interleukin-4 - immunology | Animals | Eosinophilia - immunology | Recombinant Proteins - immunology | Epithelial Cells - immunology | Receptors, Interleukin-4 - genetics | Mice | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Chemokine CCL17 - metabolism | Lung - immunology
Journal Article
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 4713
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 2012, Volume 167, Issue 1, pp. 137 - 148
...‐translational modifications and the use of immunoassays that do not always discriminate between the different forms of the same protein... 
hepatitis C virus | chemokines/monokines | bladder cancer | BCG | Hepatitis C virus | Bladder cancer | Chemokines/monokines | BACILLUS-CALMETTE-GUERIN | DIPEPTIDYL-PEPTIDASE-IV | LIGANDS CXCL9 | IFN-GAMMA | CHEMOKINE RECEPTOR CXCR3 | HEPATITIS-C-VIRUS | monokines | IMMUNOLOGY | chemokines | INTERFERON-INDUCIBLE PROTEIN-10 | LEVELS CORRELATE | ADAPTIVE IMMUNE-RESPONSES | CEREBRAL MALARIA | Enzyme-Linked Immunosorbent Assay - methods | Dipeptidyl Peptidase 4 - metabolism | Carcinoma, Transitional Cell - urine | Humans | Middle Aged | Culture Media, Conditioned - chemistry | Recombinant Fusion Proteins - analysis | Male | Neoplasm Proteins - urine | Chemokine CXCL10 - analysis | Peptide Fragments - immunology | Chemokine CXCL10 - immunology | Aged, 80 and over | Adult | Female | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Urinary Bladder Neoplasms - urine | Body Fluids - chemistry | Protein Isoforms - analysis | Inflammation | Hepatitis C, Chronic - blood | Peptide Fragments - analysis | Immunoenzyme Techniques - methods | Biomarkers | Aged | Protein Processing, Post-Translational | Protein Isoforms - immunology | Universities and colleges | Dendritic cells | Hepatitis C | Atopic dermatitis | Hepatitis | Pathogenesis | Discrimination | Urine | CD26 antigen | biomarkers | Abundance | Inflammatory diseases | Asthma | Tuberculosis | CXCL10 protein | Post-translation | Immunoassays | Injuries | Cancer | Kidney transplantation | Recombinant Fusion Proteins/analysis | Chemokine CXCL10/analysis | Hepatitis C, Chronic/blood | Culture Media, Conditioned/chemistry | Carcinoma, Transitional Cell/urine | Life Sciences | Chemokine CXCL10/immunology | Antibodies, Monoclonal/immunology | Immunology | Neoplasm Proteins/urine | Protein Isoforms/immunology | Urinary Bladder Neoplasms/urine | Body Fluids/chemistry | Peptide Fragments/immunology | Protein Isoforms/analysis | Enzyme-Linked Immunosorbent Assay/methods | Dipeptidyl Peptidase 4/metabolism | Immunoenzyme Techniques/methods | Peptide Fragments/analysis | Translational Studies
Journal Article