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Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 201 - 206
The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly,... 
PATHOGENESIS | LOCALIZES | COMPLEX | PROTEIN | BECLIN-1 | PATHWAY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | BINDING | Apoptosis Regulatory Proteins - pharmacology | Recombinant Fusion Proteins - pharmacology | Humans | Cell Membrane Permeability | Molecular Sequence Data | Peptide Fragments - pharmacology | Membrane Proteins - pharmacology | Membrane Proteins - therapeutic use | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | HIV-1 - physiology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Beclin-1 | Amino Acid Sequence | HIV-1 - metabolism | Virus Replication - drug effects | Peptide Fragments - metabolism | HIV-1 - drug effects | tat Gene Products, Human Immunodeficiency Virus - genetics | Apoptosis Regulatory Proteins - chemistry | Cells, Cultured | West Nile virus - drug effects | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Chikungunya virus - drug effects | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Mice | HeLa Cells | Apoptosis Regulatory Proteins - therapeutic use | tat Gene Products, Human Immunodeficiency Virus - metabolism | Proteins | Peptides | Microscopy | Rodents | Mortality | Amino acids | Infections | Autophagy | Index Medicus
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 521 - n/a
Synthetic biology aims to systematically design and construct novel biological systems that address energy, environment, and health issues. Herein, we describe... 
synthetic biology | Pseudomonas aeruginosa | pyocin | quorum sensing | genetic circuits | CELLS | BACTERIA | PROTEIN | SENSITIVE METHOD | SPECIFICITY | EFFICACY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMID | OTITIS | PERACETIC-ACID | BINDING | Recombinant Fusion Proteins - pharmacology | Humans | Pseudomonas aeruginosa - growth & development | Biofilms - growth & development | Escherichia coli - pathogenicity | Escherichia coli - metabolism | Homoserine - pharmacology | Homoserine - analogs & derivatives | Organisms, Genetically Modified - genetics | Genes, Reporter | Biofilms - drug effects | Recombinant Fusion Proteins - biosynthesis | Green Fluorescent Proteins - analysis | Quorum Sensing - drug effects | Pseudomonas Infections - drug therapy | 4-Butyrolactone - pharmacology | Pyocins - biosynthesis | Pseudomonas aeruginosa - drug effects | Escherichia coli - chemistry | Pseudomonas Infections - microbiology | Gene Expression Regulation, Bacterial - drug effects | Bacterial Proteins - pharmacology | Pyocins - pharmacology | Escherichia coli - genetics | Green Fluorescent Proteins - biosynthesis | Plasmids | Synthetic Biology - methods | Biosensing Techniques - methods | Anti-Bacterial Agents - biosynthesis | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | 4-Butyrolactone - analogs & derivatives | Antibiosis - genetics | Chassis | Water-borne diseases | Cell culture | Mixed culture | Escherichia coli | Fluorescence | Confocal microscopy | Infections | Biology | E7 protein | Devices | Matrix methods | Antiinfectives and antibacterials | Proteins | Engineering | Microorganisms | Microbiota | Biological weapons | E coli | Helicobacter pylori | Mathematical analysis | Bacteria | Synthetic biology | Inhibition | Public health | Killing | Pathogens | Escherichia | Damage assessment | Empirical equations | Transfer functions | Data processing | Membrane proteins | Biofilms | Infectious diseases | Antibiotics | Microscopy | Lysis | Green fluorescent protein | Strategy | Cholera | Detection | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2575 - 2575
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 02/2011, Volume 18, Issue 2, pp. 222 - 234
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2010, Volume 29, Issue 1, pp. 41 - 54
Journal Article
Science, ISSN 0036-8075, 1/2003, Volume 299, Issue 5604, pp. 223 - 226
A small molecule, α-(trichloromethyl)-4-pyridineethanol (PETCM), was identified by high-throughput screening as an activator of caspase-3 in extracts of a... 
Molecules | Gels | Cell death | HeLa cells | Small interfering RNA | Cytochromes | Biochemistry | Cell extracts | Research Article | Apoptosis | Tumors | CYTOCHROME-C | APOPTOSIS | ACTIVATION | GENE | MULTIDISCIPLINARY SCIENCES | HL-60 CELLS | DIFFERENTIATION | ACIDIC NUCLEAR-PROTEIN | EXPRESSION | CELL-DEATH | FAMILY | Deoxyadenine Nucleotides - metabolism | Caspase 9 | Protein Precursors - isolation & purification | Nuclear Proteins - isolation & purification | Protein Precursors - chemistry | Pyridines - chemistry | Humans | Molecular Sequence Data | Nuclear Proteins - pharmacology | Neuropeptides | Thymosin - analogs & derivatives | Thymosin - chemistry | Proteins - isolation & purification | Caspases - metabolism | RNA Interference | Tumor Suppressor Proteins - chemistry | Caspase 3 | Thymosin - metabolism | Recombinant Proteins - metabolism | Thymosin - isolation & purification | Amino Acid Sequence | Apoptotic Protease-Activating Factor 1 | Deoxyadenine Nucleotides - pharmacology | Tumor Suppressor Proteins - metabolism | Signal Transduction | Thymosin - pharmacology | Intracellular Signaling Peptides and Proteins | Nuclear Proteins - metabolism | Mitochondria - metabolism | Recombinant Proteins - pharmacology | Nuclear Proteins - chemistry | Cytochrome c Group - metabolism | Protein Precursors - metabolism | Protein Precursors - pharmacology | Proteins - metabolism | Tumor Suppressor Proteins - isolation & purification | Cell Extracts | Proteins - pharmacology | Pyridines - pharmacology | Enzyme Activation | HeLa Cells | Proteins - chemistry | Molecular biology | Cells | Cancer | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2012, Volume 122, Issue 6, pp. 2104 - 2113
Journal Article
Immunity, ISSN 1074-7613, 2006, Volume 25, Issue 4, pp. 607 - 617
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2014, Volume 10, Issue 4, pp. 305 - 312
Journal Article