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Nature Structural & Molecular Biology, ISSN 1545-9993, 10/2010, Volume 17, Issue 10, pp. 1247 - 1254
Inherited mutations in human PALB2 are associated with a predisposition to breast and pancreatic cancers. PALB2's tumor-suppressing effect is thought to be... 
POLY(ADP-RIBOSE) POLYMERASE | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | HISTONE H2AX | FANCONI-ANEMIA | CELL BIOLOGY | RAD51 | BIOPHYSICS | IN-VIVO | SUSCEPTIBILITY GENE | D-LOOP FORMATION | DNA-REPAIR | Recombination, Genetic - physiology | DNA, Neoplasm - metabolism | Humans | Neoplasm Proteins - physiology | DNA Repair - physiology | Molecular Sequence Data | Structure-Activity Relationship | DNA Breaks, Double-Stranded | BRCA2 Protein - physiology | Breast Neoplasms - metabolism | Base Sequence | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Female | Protein Interaction Domains and Motifs | Nuclear Proteins - genetics | Nucleic Acid Conformation | Fanconi Anemia Complementation Group N Protein | Peptide Fragments - metabolism | Neoplasm Proteins - chemistry | Nuclear Proteins - chemistry | Poly(ADP-ribose) Polymerase Inhibitors | Protein Interaction Mapping | Tumor Suppressor Proteins - physiology | Peptide Fragments - chemistry | Apoptosis Regulatory Proteins | Models, Biological | Rad51 Recombinase - chemistry | Rad51 Recombinase - physiology | BRCA2 Protein - chemistry | Nuclear Proteins - physiology | Poly (ADP-Ribose) Polymerase-1 | Breast cancer | Genetic aspects | Research | BRCA mutations | Ovarian cancer | Proteins | Mutation | Molecular biology | Prostate cancer | homologous recombination | BRCA2 | PALB2
Journal Article
Chemistry & Biology, ISSN 1074-5521, 06/2015, Volume 22, Issue 6, pp. 712 - 723
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 12/2013, Volume 20, Issue 12, pp. 1425 - 1433
Chromatin ubiquitylation flanking DNA double-strand breaks (DSBs), mediated by RNF8 and RNF168 ubiquitin ligases, orchestrates a two-branch pathway, recruiting... 
53BP1 RECRUITMENT | RESECTION | UBIQUITIN E3 LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | BRCA1 | CELL BIOLOGY | DAMAGE RESPONSE | REPAIR | BIOPHYSICS | HOMOLOGOUS RECOMBINATION | RAP80 | BINDING | Humans | Jumonji Domain-Containing Histone Demethylases - physiology | Oxidoreductases, N-Demethylating - physiology | Trans-Activators - chemistry | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | DNA Methylation | Ubiquitination | BRCA1 Protein - metabolism | DNA Breaks | Jumonji Domain-Containing Histone Demethylases - chemistry | Carrier Proteins - chemistry | Female | Tumor Cells, Cultured | Oxidoreductases, N-Demethylating - metabolism | BRCA1 Protein - chemistry | Rad51 Recombinase - metabolism | DNA-Binding Proteins - physiology | BRCA1 Protein - physiology | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Poly(ADP-ribose) Polymerase Inhibitors | Oxidoreductases, N-Demethylating - chemistry | Breast Neoplasms - genetics | Carrier Proteins - metabolism | Rad51 Recombinase - chemistry | Rad51 Recombinase - physiology | Trans-Activators - metabolism | HeLa Cells | Jumonji Domain-Containing Histone Demethylases - metabolism | Genetic markers | Care and treatment | DNA damage | Genetic aspects | Research | Identification and classification | Cancer | Proteins | Signal transduction | Chromatin | DNA repair
Journal Article
The FEBS Journal, ISSN 1742-464X, 09/2011, Volume 278, Issue 18, pp. 3447 - 3462
The occurrence of DNA architectural proteins containing two functional domains derived from two different architectural proteins is an interesting emerging... 
DNA supercoiling | DNA strand exchange | HU protein | HupB protein | nucleoid | HISTONE-LIKE PROTEIN | SINGLE | FORM | IHF | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | ESCHERICHIA-COLI HU | NUCLEOID-ASSOCIATED PROTEINS | IN-VITRO | GENES | GROWTH | Polydeoxyribonucleotides - metabolism | Transcription Factors - chemistry | Bacterial Proteins - chemistry | Mutant Proteins - isolation & purification | DNA, Bacterial - chemistry | Recombination, Genetic | Dimerization | Peptide Fragments - genetics | Rec A Recombinases - metabolism | Recombinant Proteins - chemistry | DNA-Binding Proteins - chemistry | Histones - isolation & purification | Peptide Fragments - chemistry | Transcription Factors - isolation & purification | Histones - metabolism | Kinetics | DNA, Superhelical - metabolism | Escherichia coli Proteins - chemistry | DNA, Bacterial - metabolism | Histones - chemistry | Rec A Recombinases - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Recombinant Proteins - isolation & purification | DNA, Superhelical - chemistry | Escherichia coli - metabolism | Carrier Proteins - chemistry | Protein Interaction Domains and Motifs | Protein Stability | Mycobacterium tuberculosis - metabolism | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Cross-Linking Reagents - chemistry | Peptide Fragments - isolation & purification | Bacterial Proteins - genetics | Escherichia coli Proteins - metabolism | Mutant Proteins - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - isolation & purification | Escherichia coli Proteins - isolation & purification | Transcription Factors - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Histones - genetics | Polydeoxyribonucleotides - chemistry | Carrier Proteins - isolation & purification | Mutant Proteins - chemistry | Escherichia coli Proteins - genetics | Bacterial Proteins - metabolism | Bacterial Proteins - isolation & purification | Proteins | Tuberculosis | Analysis | Escherichia coli | DNA | Genetic research | Chemical properties
Journal Article
ChemBioChem, ISSN 1439-4227, 02/2013, Volume 14, Issue 3, pp. 332 - 342
Journal Article
Science, ISSN 0036-8075, 9/2012, Volume 337, Issue 6099, pp. 1222 - 1225
Journal Article
Journal Article