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Journal Article
Diabetes, ISSN 0012-1797, 03/2013, Volume 62, Issue 3, pp. 864 - 874
Journal Article
Molecular Plant Pathology, ISSN 1464-6722, 2017, Volume 18, Issue 1, pp. 75 - 89
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 16, pp. 6492 - 6496
Interstrand cross-links (ICLs) block replication and transcription and thus are highly cytotoxic. In higher eukaryotes, ICLs processing involves the Fanconi... 
Enzymes | Cell growth | Fanconi anemia | Genetic vectors | DNA damage | DNA | Homologous recombination | Cell cycle | DNA repair | Chromosome aberrations | Mitomycin C | Endonuclease | Cisplatin | STRUCTURE-SPECIFIC ENDONUCLEASE | mitomycin C | MONOUBIQUITINATED FANCD2 | KIAA1018/FAN1 | MULTIDISCIPLINARY SCIENCES | STRUCTURE-SPECIFIC NUCLEASES | IDENTIFICATION | endonuclease | HOLLIDAY JUNCTION RESOLVASE | GENE | ERCC1/XPF ENDONUCLEASE | HOMOLOGOUS RECOMBINATION | cisplatin | Endonucleases - genetics | Recombination, Genetic - physiology | Fanconi Anemia Complementation Group D2 Protein - genetics | Recombinases - genetics | Chromatids - genetics | Cross-Linking Reagents - pharmacology | DNA Repair - physiology | Multiprotein Complexes - genetics | Endonucleases - metabolism | Chromatids - metabolism | Multiprotein Complexes - metabolism | Ubiquitination - drug effects | Cell Death - genetics | Chromosome Aberrations - drug effects | DNA Damage - physiology | Cell Death - drug effects | Ubiquitination - physiology | DNA Damage - drug effects | Cell Line | DNA Repair - drug effects | Recombinases - metabolism | Zinc Fingers | Animals | Fanconi Anemia Complementation Group D2 Protein - metabolism | Chickens | Cell Proliferation - drug effects | Recombination, Genetic - drug effects | Nucleases | Crosslinked polymers | Physiological aspects | Development and progression | Genetic aspects | Research | Health aspects | Protein binding | Fanconi's anemia | Biological Sciences
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 04/2017, Volume 24, Issue 4, pp. 353 - 361
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2013, Volume 288, Issue 33, pp. 24173 - 24188
The oil from flax (Linum usitatissimum L.) has high amounts of alpha-linolenic acid (ALA; 18:3(cis Delta 9,12,15)) and is one of the richest sources of omega-3... 
ARABIDOPSIS-THALIANA | TRIACYLGLYCEROL BIOSYNTHESIS | LIPID-SYNTHESIS | FUNCTIONAL EXPRESSION | BRASSICA-NAPUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYUNSATURATED FATTY-ACIDS | TRANSGENIC PLANTS | ENDOPLASMIC-RETICULUM | SACCHAROMYCES-CEREVISIAE | ALPHA-LINOLENIC ACID | Organ Specificity - drug effects | Flax - genetics | Gas Chromatography-Mass Spectrometry | Triglycerides - biosynthesis | Saccharomyces cerevisiae - genetics | Seeds - enzymology | Esters - metabolism | Saccharomyces cerevisiae - drug effects | Gene Expression Profiling | Acyltransferases - metabolism | Acyltransferases - genetics | Genetic Complementation Test | alpha-Linolenic Acid - pharmacology | Organ Specificity - genetics | Biocatalysis - drug effects | Plants, Genetically Modified | Recombination, Genetic - genetics | Real-Time Polymerase Chain Reaction | Arabidopsis - drug effects | Seeds - drug effects | Seeds - genetics | Flax - enzymology | Mutation - genetics | Flax - drug effects | Arabidopsis - genetics | Gene Expression Regulation, Plant - drug effects | Phenotype | Substrate Specificity - drug effects | Genes, Plant - genetics | Plant Oils - metabolism | Diacylglycerol O-Acyltransferase - metabolism | Recombination, Genetic - drug effects | Saccharomyces cerevisiae - growth & development | Metabolic Engineering | Molecular Genetics | Phospholipid:diacylglycerol Acyltransferases | Triacylglycerol | Lipids | Lipid Metabolism | Plant Molecular Biology | Flax | α-Linolenic Acid
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9851 - 9856
Defective homologous recombination (HR) DNA repair imposed by BRCA1 or BRCA2 deficiency sensitizes cells to poly (ADP-ribose) polymerase (PARP)-1 inhibition... 
B lymphocytes | Homologous recombination | Cell lines | HeLa cells | Small interfering RNA | Immunoblotting | CHO cells | Hyperthermia | Cells | Tumors | Double-strand break | Anti-cancer treatment | RAD51 | PATHWAYS | NUDE-MICE | MUTANT | MECHANISM | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | COMBINATION | REPAIR | double-strand break | anti-cancer treatment | PHASE-I | SISTER-CHROMATID EXCHANGES | THERMAL RADIOSENSITIZATION | Embryonic Stem Cells - metabolism | Humans | Transplantation, Heterologous | DNA-Binding Proteins - metabolism | Neoplasms, Experimental - pathology | RNA Interference | Embryonic Stem Cells - radiation effects | Neoplasms, Experimental - genetics | Recombination, Genetic - genetics | Female | Cell Line | Cells, Cultured | Rats | Hot Temperature | DNA-Binding Proteins - genetics | Lactams, Macrocyclic - pharmacology | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | Benzoquinones - pharmacology | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Animals | BRCA2 Protein - metabolism | Poly(ADP-ribose) Polymerases - genetics | Embryonic Stem Cells - drug effects | Tumor Burden - drug effects | Mice, Nude | DNA Repair | Cell Line, Tumor | Mice | Recombination, Genetic - radiation effects | HeLa Cells | Neoplasms, Experimental - metabolism | Quinazolines - pharmacology | BRCA2 Protein - genetics | Recombination, Genetic - drug effects | BRCA mutations | Proteolysis | Cancer cells | Genetic aspects | Research | Genetic recombination | Health aspects | Fever | Cancer | Biological Sciences
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, pp. 14432 - 14432
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 483 - 493
Activation-induced cytidine deaminase (AID) is a B-cell-specific enzyme that targets immunoglobulin genes to initiate class switch recombination and somatic... 
SUPER-ENHANCERS | INDUCED CYTIDINE DEAMINASE | DNA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | IBRUTINIB | CLASS-SWITCH RECOMBINATION | MECHANISMS | TARGETING BTK | AID | SEQUENCING REVEALS | Isoquinolines - adverse effects | Class I Phosphatidylinositol 3-Kinases - metabolism | Humans | Lymphoma, Mantle-Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Translocation, Genetic - drug effects | Isoquinolines - pharmacology | Antineoplastic Agents - adverse effects | Genomic Instability - drug effects | Female | Antineoplastic Agents - pharmacology | Purines - adverse effects | B-Lymphocytes - pathology | Immunoglobulin Class Switching - drug effects | Somatic Hypermutation, Immunoglobulin - drug effects | Lymphoma, Mantle-Cell - genetics | B-Lymphocytes - metabolism | Quinazolinones - pharmacology | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Enzyme Inhibitors - adverse effects | B-Lymphocytes - enzymology | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Pyrimidines - pharmacology | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | B-Lymphocytes - drug effects | Animals | Agammaglobulinaemia Tyrosine Kinase | Cytidine Deaminase - metabolism | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Immunoglobulin Heavy Chains - genetics | Quinazolinones - adverse effects | Recombination, Genetic - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article