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European urology, ISSN 0302-2838, 2016, Volume 71, Issue 3, pp. 417 - 425
Urology | BRCA | PARP | Personalized medicine | Prostate cancer | DNA repair | DNA damage | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Prognosis | Recombinational DNA Repair - genetics | Humans | Male | MutS Homolog 2 Protein - genetics | DNA Repair - genetics | Prostatic Neoplasms, Castration-Resistant - drug therapy | DNA Mismatch Repair - genetics | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | Prostatic Neoplasms, Castration-Resistant - genetics | BRCA1 Protein - genetics | Molecular Diagnostic Techniques | Prostatic Neoplasms - genetics | MutL Protein Homolog 1 - genetics | Ataxia Telangiectasia Mutated Proteins - genetics | BRCA2 Protein - genetics | Prostatic Neoplasms - drug therapy | Precision Medicine | DNA | Therapeutics | Genetic aspects | Research institutes | Homeopathy | Materia medica and therapeutics | Cancer | Medical research | Medicine, Experimental | Genetic research | Index Medicus
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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
Nature (London), ISSN 0028-0836, 05/2015, Volume 521, Issue 7553, pp. 537 - 540
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genomic Instability | Mad2 Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins - metabolism | DNA End-Joining Repair - genetics | Recombinational DNA Repair - genetics | Humans | Ubiquitin-Protein Ligases - metabolism | DNA Replication | Nuclear Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded - radiation effects | DNA-Binding Proteins - metabolism | Carrier Proteins - metabolism | DNA Repair Enzymes - metabolism | Exodeoxyribonucleases - metabolism | Cell Line, Tumor | Telomere - metabolism | Tumor Suppressor p53-Binding Protein 1 | Telomere-Binding Proteins - metabolism | Telomere - genetics | DNA polymerases | Telomeres | DNA repair | Analysis | Phosphorylation | Kinases | Telomerase | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
2014, ISBN 9780815344858, xvi, 399
Book
Nature cell biology, ISSN 1465-7392, 08/2018, Volume 20, Issue 8, pp. 954 - 965
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Osteosarcoma - drug therapy | Mad2 Proteins - metabolism | Humans | Multiprotein Complexes | Ovarian Neoplasms - pathology | Bone Neoplasms - pathology | DNA Breaks, Double-Stranded | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Ovarian Neoplasms - genetics | Telomere-Binding Proteins - genetics | DNA End-Joining Repair | HEK293 Cells | Female | Bone Neoplasms - genetics | Ovarian Neoplasms - metabolism | Bone Neoplasms - drug therapy | BRCA1 Protein - deficiency | Telomere-Binding Proteins - metabolism | Ovarian Neoplasms - drug therapy | Osteosarcoma - metabolism | DNA-Binding Proteins | Tumor Suppressor p53-Binding Protein 1 - metabolism | Recombinational DNA Repair | Tumor Suppressor p53-Binding Protein 1 - genetics | Cisplatin - pharmacology | Breast Neoplasms - drug therapy | Proteins - genetics | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Proteins - metabolism | Breast Neoplasms - pathology | Mad2 Proteins - genetics | Cell Line, Tumor | Mice | Osteosarcoma - genetics | Cell Cycle Proteins | Osteosarcoma - pathology | Care and treatment | DNA | Cancer cells | Breast cancer | Genetic aspects | Research | Gene expression | Single-stranded DNA | DNA damage | Homologous recombination | Poly(ADP-ribose) | Homology | Genomes | Inactivation | Proteins | Ribose | Null cells | Deoxyribonucleic acid--DNA | BRCA2 protein | CRISPR | Deactivation | BRCA1 protein | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Oligosaccharides | Double-strand break repair | Screens | Cisplatin | Inhibitors | Prostate | Viability | Tumors | Index Medicus | Telomere-Binding Proteins / metabolism | Osteosarcoma / genetics | Telomere-Binding Proteins / genetics | BRCA1 Protein / genetics | Cellular Biology | Genetics | Proteins / genetics | Osteosarcoma / drug therapy | Ovarian Neoplasms / genetics | Mad2 Proteins / genetics | Proteins / metabolism | Breast Neoplasms / drug therapy | Breast Neoplasms / metabolism | Tumor Suppressor p53-Binding Protein 1 / genetics | BRCA1 Protein / deficiency | Ovarian Neoplasms / metabolism | Mad2 Proteins / metabolism | Breast Neoplasms / pathology | Bone Neoplasms / genetics | Ovarian Neoplasms / pathology | Bone Neoplasms / pathology | Life Sciences | Bone Neoplasms / drug therapy | Ovarian Neoplasms / drug therapy | Osteosarcoma / metabolism | Biochemistry, Molecular Biology | Breast Neoplasms / genetics | Drug Resistance, Neoplasm / genetics | Osteosarcoma / pathology | Bone Neoplasms / metabolism | Poly(ADP-ribose) Polymerase Inhibitors / pharmacology | Cisplatin / pharmacology | Molecular biology | Tumor Suppressor p53-Binding Protein 1 / metabolism | Cancer
Journal Article
Chromosoma, ISSN 0009-5915, 6/2018, Volume 127, Issue 2, pp. 187 - 214
Biochemistry, general | Human Genetics | DNA double-strand break repair | Homologous recombination | Meiosis | DNA end resection | Cell Biology | Life Sciences | DNA strand exchange | Replication stress | End-joining | Developmental Biology | Animal Genetics and Genomics | Eukaryotic Microbiology | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Rad51 Recombinase - metabolism | Recombinational DNA Repair | Rad51 Recombinase - genetics | Humans | Gene Expression Regulation | DNA Replication | Eukaryotic Cells - metabolism | Nuclear Proteins - metabolism | DNA - metabolism | DNA Breaks, Double-Stranded | DNA - genetics | Animals | DNA End-Joining Repair | DNA, Cruciform | Eukaryotic Cells - cytology | MRE11 Homologue Protein - metabolism | Nuclear Proteins - genetics | MRE11 Homologue Protein - genetics | Proteins | Biotechnology | Chemotherapy | DNA replication | DNA | Cancer | Yeast | DNA damage | Radiation therapy | Double-strand break repair | DNA repair | DNA biosynthesis | Vegetative cells | Mutagenesis | Lymphocytes | Non-homologous end joining | Genetic recombination | Deoxyribonucleic acid--DNA | Immune system | Index Medicus
Journal Article
DNA repair, ISSN 1568-7864, 08/2016, Volume 44, pp. 22 - 32
Alternative end-joining | MMEJ | DNA synthesis | Synthetic lethality | DNA polymerase | DNA double strand breaks | Toxicology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Gamma Rays | Enzyme Inhibitors | DNA, Neoplasm - metabolism | Humans | Base Pair Mismatch | DNA-Directed DNA Polymerase - chemistry | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | Neoplasms - therapy | Neoplasms - genetics | DNA End-Joining Repair | DNA Mismatch Repair | Catalytic Domain | Recombinational DNA Repair | Antineoplastic Combined Chemotherapy Protocols | Models, Molecular | Neoplasms - enzymology | Treatment Outcome | DNA - metabolism | DNA - genetics | Animals | DNA, Neoplasm - antagonists & inhibitors | DNA, Neoplasm - genetics | DNA-Directed DNA Polymerase - metabolism | Neoplasms - pathology | Index Medicus | alternative end-joining | synthetic lethality
Journal Article