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Gut, ISSN 0017-5749, 06/2012, Volume 61, Issue 6, pp. 847 - 854
ObjectiveColorectal cancer is typically classified into proximal colon, distal colon and rectal cancer. Tumour genetic and epigenetic features differ by tumour... 
ISLAND METHYLATOR PHENOTYPE | COLON-CANCER | POPULATION-BASED SAMPLE | DNA METHYLATION | LINE-1 HYPOMETHYLATION | BRAF MUTATION | MICROSATELLITE INSTABILITY | BODY-MASS INDEX | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | P-GLYCOPROTEIN | ras Proteins - genetics | Colonic Neoplasms - genetics | Microsatellite Instability | Proto-Oncogene Proteins p21(ras) | Cecal Neoplasms - pathology | Colorectal Neoplasms - genetics | Humans | Long Interspersed Nucleotide Elements - genetics | Male | Colonic Neoplasms - metabolism | Sigmoid Neoplasms - genetics | Rectal Neoplasms - genetics | Female | Rectal Neoplasms - pathology | Colorectal Neoplasms - metabolism | Cecal Neoplasms - genetics | Mutation Rate | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Mutation - genetics | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | CpG Islands - genetics | Aged | Rectal Neoplasms - metabolism | DNA, Neoplasm - genetics | Colorectal Neoplasms - pathology | Sigmoid Neoplasms - pathology | Development and progression | Genetic aspects | Colon (Anatomy) | Research | Gene mutations | Colorectal cancer | Medical personnel | Studies | Hypotheses | Hospitals | Biopsy | Rodents | Epigenetics | Mutation | Data bases | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
by Zhang, Bing and Zhang, Bing and Wang, Jing and Wang, Jing and Wang, Xiaojing and Wang, Xiaojing and Zhu, Jing and Zhu, Jing and Liu, Q and Liu, Qi and Shi, Zhiao and Shi, Zhiao and Chambers, Matthew C and Chambers, Matthew C and Zimmerman, Lisa J and Zimmerman, Lisa J and Shaddox, Kent F and Shaddox, Kent F and Kim, Sangtae and Kim, Sangtae and Davies, Sherri R and Davies, Sherri R and Wang, Sean and Wang, Sean and Wang, Pei and Wang, Pei and Kinsinger, Christopher R and Kinsinger, Christopher R and Rivers, Robert C and Rivers, Robert C and Rodriguez, Henry and Rodriguez, Henry and Townsend, R. Reid and Townsend, R Reid and Ellis, Matthew J. C and Ellis, Matthew J C and Carr, Steven A and Carr, Steven A and Tabb, David L and Tabb, David L and Coffey, Robert J and Coffey, Robert J and Slebos, Robbert J C and Slebos, Robbert J. C and Liebler, Daniel C and Liebler, Daniel C and NCI CPTAC, CPTAC and Gillette, Michael A and Klauser, Karl R and Kuhn, Eric and Mani, D.R and Mertins, Philipp and Ketchum, Karen A and Paulovich, Amanda G and Whiteaker, Jeffrey R and Edwards, Nathan J and McGarvey, Peter B and Madhavan, Subha and Chan, Daniel and Pandey, Akhilesh and Shih, Ie-Ming and Zhang, Hui and Zhang, Zhen and Zhu, Heng and Whiteley, Gordon A and Skates, Steven J and White, Forest M and Levine, Douglas A and Boja, Emily S and Hiltke, Tara and Mesri, Mehdi and Shaw, Kenna M and Stein, Stephen E and Fenyo, David and Liu, Tao and McDermott, Jason E and Payne, Samuel H and Rodland, Karin D and Smith, Richard D and Rudnick, Paul and Snyder, Michael and Zhao, Yingming and Chen, Xian and Ransohoff, David F and Hoofnagle, Andrew N and Sanders, Melinda E and Wang, Yue and Ding, Li and NCI CPTAC and the NCI CPTAC
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7518, pp. 382 - 387
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 6, pp. 738 - 746
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2013, Volume 230, Issue 3, pp. 261 - 269
Journal Article
Journal Article
Nature medicine, ISSN 1078-8956, 2015, Volume 21, Issue 11, pp. 1350 - 1356
Journal Article
Gut, ISSN 0017-5749, 04/2017, Volume 66, Issue 4, pp. 633 - 643
Journal Article
Cancer, ISSN 0008-543X, 05/2014, Volume 120, Issue 10, pp. 1482 - 1490
In this study, NRAS mutations were observed almost exclusively in rectal cancers compared with colon cancers. This result suggests that there may be a biologic... 
mutation | NRAS | BRAF | colorectal cancer | clinicopathologic | ASSOCIATIONS | CODON 12 | COLON-CANCER | RECTAL-CANCER | CIGARETTE-SMOKING | POLYMORPHISMS | ONCOLOGY | TUMOR SITE | CARCINOMAS | KRAS | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Rectal Neoplasms - chemistry | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Proto-Oncogene Proteins B-raf - analysis | Rectal Neoplasms - genetics | DNA Mutational Analysis | Aged, 80 and over | Adult | Colonic Neoplasms - chemistry | Female | Adenocarcinoma - genetics | Rectal Neoplasms - pathology | Retrospective Studies | Adenocarcinoma - chemistry | Adenomatous Polyposis Coli Protein - genetics | Colonic Neoplasms - mortality | Biomarkers, Tumor - analysis | Membrane Proteins - genetics | Risk Factors | Kaplan-Meier Estimate | Genotype | Proto-Oncogene Proteins - genetics | Adenocarcinoma - secondary | Rectal Neoplasms - mortality | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | GTP Phosphohydrolases - genetics | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Mutation | Neoplasm Staging | Adenocarcinoma - mortality | Care and treatment | Usage | Colorectal cancer | Genetic aspects | Metastasis | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e94376 - e94376
Purpose: Tumor-infiltrating FoxP3(+) T cells have been reported in various human tumors, which impaired cell-mediated immunity and promoted disease... 
SURVIVAL | HEPATOCELLULAR-CARCINOMA | GASTRIC-CANCER | CLINICAL IMPACT | COLORECTAL-CANCER | POOR-PROGNOSIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | RECURRENCE | ADVERSE PROGNOSIS | EXPRESSION | Carcinoma, Hepatocellular - mortality | Prognosis | Colorectal Neoplasms - genetics | Humans | Male | Stomach Neoplasms - pathology | Liver Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Colorectal Neoplasms - diagnosis | Neoplasm Recurrence, Local - pathology | Forkhead Transcription Factors - metabolism | Carcinoma, Hepatocellular - genetics | Female | Liver Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - metabolism | Odds Ratio | Colorectal Neoplasms - mortality | Stomach Neoplasms - genetics | Gene Expression | Stomach Neoplasms - diagnosis | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - diagnosis | Neoplasm Recurrence, Local - diagnosis | Forkhead Transcription Factors - genetics | Liver Neoplasms - diagnosis | Lymphocytes, Tumor-Infiltrating - pathology | Carcinoma, Hepatocellular - pathology | Survival Analysis | Neoplasm Recurrence, Local - genetics | Colorectal Neoplasms - pathology | Stomach Neoplasms - mortality | Laboratories | Colorectal carcinoma | Colorectal cancer | Clinical trials | Hepatocellular carcinoma | Systematic review | Lymphocytes T | Immunity | Stomach cancer | Immunity (cell-mediated) | Metastases | Confidence intervals | Liver cancer | Lymphocytes | Hepatology | Surgery | Foxp3 protein | Gastric cancer | Cell survival | Patients | Survival | Studies | Hospitals | Medical prognosis | Infiltration | Tumors | Cancer | Index Medicus
Journal Article