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PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68332
Previously, we screened a proteoglycan for anti-hyperglycemic, named FYGL, from Ganoderma Lucidum. For further research of the antidiabetic mechanisms of FYGL... 
INSULIN | CELLS | PROTEIN | MESSENGER-RNA | TYROSINE-PHOSPHATASE 1B | MULTIDISCIPLINARY SCIENCES | LIVER | RESISTANCE | GLUCOKINASE | EXTRACTS | GENE-TRANSCRIPTION | Islets of Langerhans - drug effects | Liver - enzymology | C-Peptide - blood | Antioxidants - metabolism | Glycated Hemoglobin A - metabolism | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Liver - drug effects | Islets of Langerhans - metabolism | Muscle, Skeletal - drug effects | C-Peptide - metabolism | Disease Models, Animal | Glucose Transporter Type 4 | Glucose Transporter Type 2 | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Glucokinase - metabolism | Hypolipidemic Agents - pharmacology | Reishi - metabolism | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Animals | Proteoglycans - pharmacology | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Glucose - metabolism | Mice | Oxidative Stress - drug effects | Diabetes Mellitus, Type 2 - drug therapy | Biological Factors - pharmacology | Antioxidants | Isoenzymes | Analysis | Anticholesteremic agents | Muscles | Glycosylated hemoglobin | Amino acids | Hypoglycemic agents | Glucose | Dextrose | Oxidative stress | Animal models | Laboratories | Homeostasis | Pyruvic acid | Phosphatase | Fruit bodies | Proteins | Engineering | Signal transduction | Reduction | Hyperglycemia | Chinese medicine | Rodents | Hemoglobin | Protein transport | Pancreas | Polymers | Drug dosages | Glucose transporter | Enzymes | Ganoderma lucidum | Secretion | Complications | Diabetes mellitus | Metabolism | Insulin | Skeletal muscle | Herbal medicine | Glucokinase | Diabetes | Transporter
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2004, Volume 173, Issue 10, pp. 5989 - 5999
We have demonstrated that an extract of Ganoderma lucidum (Reishi or Ling-Zhi) polysaccharides (EORP) exerts immunomodulating activities by stimulating the... 
FRUITING BODY | SCAVENGER RECEPTOR | PGG-GLUCAN | N-TERMINAL KINASE | TOLL-LIKE RECEPTORS | IMMUNOLOGY | GANODERMA-LUCIDUM | ACTIVE POLYSACCHARIDES | ANTITUMOR ACTIVITIES | ASPERGILLUS-FUMIGATUS CONIDIA | LECTIN SITE | Polymyxin B - pharmacology | Interleukin-1 - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Toll-Like Receptor 4 | Membrane Glycoproteins - metabolism | Humans | Reactive Oxygen Species - pharmacology | Caspase 1 - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Enzyme Activation - immunology | Interleukin-1 - biosynthesis | RNA, Messenger - biosynthesis | Signal Transduction - immunology | Toll-Like Receptors | Membrane Glycoproteins - physiology | Receptors, Cell Surface - physiology | p38 Mitogen-Activated Protein Kinases - metabolism | Chromones - pharmacology | Macrophages - immunology | Cell Line | Interleukin-1 - metabolism | Protein Precursors - genetics | Immunologic Factors - physiology | Cells, Cultured | Morpholines - pharmacology | Receptors, Cell Surface - metabolism | Enzyme Activation - drug effects | Reishi - metabolism | Mice, Inbred C3H | Polysaccharides - pharmacology | Macrophages - enzymology | Polysaccharides - metabolism | Macrophages - metabolism | Tyrosine - metabolism | Animals | Up-Regulation - immunology | Protein Precursors - biosynthesis | Lipopolysaccharides - analysis | Protein Kinases - physiology | Reishi - immunology | Phosphatidylinositol 3-Kinases - physiology | Mice | Immunologic Factors - metabolism | Cytokines - biosynthesis
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 10/2018, Volume 49, Issue 3, pp. 1204 - 1220
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e53616
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of... 
SIGNAL-TRANSDUCTION | CARCINOMA-CELLS | YEAST | PATHWAYS | OXIDATIVE STRESS | IN-VITRO | CANCER CELLS | NATURAL-PRODUCTS | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DIFFERENTIATION | Transcription, Genetic - drug effects | Intramolecular Transferases - genetics | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Farnesyl-Diphosphate Farnesyltransferase - genetics | RNA, Messenger - genetics | Biomass | RNA, Messenger - metabolism | Reishi - genetics | Cell Culture Techniques - methods | Reishi - metabolism | Farnesyl-Diphosphate Farnesyltransferase - metabolism | Intramolecular Transferases - metabolism | Gene Expression Regulation, Fungal - drug effects | Cell Nucleus - metabolism | Time Factors | Reishi - drug effects | Reishi - cytology | Aspirin - pharmacology | DNA Fragmentation - drug effects | Phosphorylation - drug effects | Cell Nucleus - drug effects | Triterpenes - metabolism | Mitogen-Activated Protein Kinases - metabolism | Aspirin | Metabolites | Functional foods | Natural gas | Apoptosis | Cell culture | Phosphorylation | Genes | Homology | Biosynthesis | Kinases | Fungi | Signal transduction | Lanosterol synthase | Pharmaceutical sciences | Lanosterol | Ganoderma lucidum | Cyclin-dependent kinases | Ganoderic acid | Squalene | MAP kinase | Acid production | Mammals | Gene expression | DNA nucleotidylexotransferase | Studies | Herbal medicine | Medicine | Signaling | Acids | Cancer
Journal Article
International Journal of Food Sciences and Nutrition, ISSN 0963-7486, 2/2014, Volume 65, Issue 1, pp. 42 - 47
Abstract A detailed comparative study on chemical and bioactive properties of wild and cultivated Ganoderma lucidum from Serbia (GS) and China (GCN) was... 
Antimicrobial activity | Ganoderma lucidum | antioxidant activity | chemical composition | cytotoxicity | Cytotoxicity | Chemical composition | Antioxidant activity | PORTUGAL | MEDICINAL MUSHROOMS | FOOD SCIENCE & TECHNOLOGY | CHROMATOGRAPHY | WILD MUSHROOMS | ANTIOXIDANT PROPERTIES | FR. KARST | MOLECULES | NUTRITION & DIETETICS | INHIBITION | NUTRIENTS | EXTRACTS | Anti-Infective Agents - metabolism | Nutritive Value | Humans | Crops, Agricultural - growth & development | Gram-Negative Bacteria - metabolism | Functional Food - analysis | Dietary Supplements - analysis | Breast Neoplasms - metabolism | Antineoplastic Agents - metabolism | Breast Neoplasms - diet therapy | Uterine Cervical Neoplasms - metabolism | Antineoplastic Agents - adverse effects | Anti-Infective Agents - chemistry | China | Female | Crops, Agricultural - chemistry | Reishi - chemistry | Dietary Supplements - adverse effects | Gram-Positive Bacteria - growth & development | Serbia | Anti-Infective Agents - adverse effects | Uterine Cervical Neoplasms - diet therapy | Liver - metabolism | Wilderness | Cells, Cultured | Complex Mixtures - chemistry | Mitosporic Fungi - metabolism | Complex Mixtures - metabolism | Antineoplastic Agents - chemistry | Reishi - growth & development | Reishi - metabolism | Complex Mixtures - adverse effects | Gram-Positive Bacteria - metabolism | Animals | Gram-Negative Bacteria - growth & development | Cell Line, Tumor | Mitosporic Fungi - growth & development | Liver - cytology | Sus scrofa | Crops, Agricultural - metabolism | Reishi | Cytokinins | Anti-infective agents | Chemical properties | Research | liquid-chromatography | fruiting body | polysaccharides | antioxidant properties | portugal | molecules | fr. karst | medicinal mushrooms | wild mushrooms | nutrients
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 06/2014, Volume 68, pp. 183 - 189
Journal Article
Environmental Microbiology, ISSN 1462-2912, 11/2017, Volume 19, Issue 11, pp. 4657 - 4669
Journal Article
Journal Article