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Current Biology, ISSN 0960-9822, 08/2018, Volume 28, Issue 15, pp. 2479 - 2486.e4
Organ development depends on the integration of coordinated long-range communication between cells. The cerebrospinal fluid composition and flow properties... 
Reissner fiber | development | central canal | cerebrospinal fluid | body axis morphogenesis | cilia | zebrafish | fluid dynamics | extracellular protein | ZEBRAFISH | PROTEIN | IDIOPATHIC SCOLIOSIS | FLOOR PLATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SCO-SPONDIN | SUBCOMMISSURAL ORGAN | NEUROGENESIS | CILIA MOTILITY | BRAIN | SUBSTANCE | CELL BIOLOGY | Fluid dynamics | Analysis
Journal Article
International Journal of Developmental Biology, ISSN 0214-6282, 2017, Volume 61, Issue 10-12, pp. 655 - 664
The vertebrate brain is arguably the most complex anatomical and functional structure in nature. During embryonic development, the central nervous system (CNS)... 
Bauplan | DiMes | Vertebrate CNS | Brain partition | Cephalochordate | MIDBRAIN DEVELOPMENT | cephalochordate | SENSORY PATHWAYS | FIELD TRANSCRIPTION FACTORS | DEVELOPMENTAL BIOLOGY | REISSNERS SUBSTANCE | brain partition | EXPRESSION PATTERNS | bauplan | FLOOR PLATE | BRANCHIOSTOMA-LANCEOLATUM | HOMEOBOX GENE | vertebrate CNS | DEVELOPMENTAL EXPRESSION | ISTHMIC ORGANIZER
Journal Article
Developmental Neurobiology, ISSN 1932-8451, 02/2008, Volume 68, Issue 2, pp. 209 - 222
Within the vestibular system of virtually all vertebrate species, gravity and linear acceleration are detected via coupling of calcified masses to the cilia of... 
Reissner's Substance | zebrafish | otoconin | matrix protein | Otoc1 | otolith | Zebrafish | Matrix protein | Reissner's substance | Otoconin | Otolith | MATRIX | INNER-EAR | SCO-SPONDIN | MAJOR PROTEIN | DEVELOPMENTAL BIOLOGY | REISSNERS SUBSTANCE | NEUROSCIENCES | FLOOR PLATE | GENE | BOVINE SUBCOMMISSURAL ORGAN | FIBER COMPLEX | SECRETORY GLYCOPROTEINS | Otolithic Membrane - metabolism | Brain - embryology | Gene Expression Regulation, Developmental - genetics | Molecular Sequence Data | RNA, Messenger - analysis | Phylogeny | RNA, Antisense - pharmacology | Vestibule, Labyrinth - metabolism | Calcium Carbonate - metabolism | RNA, Messenger - metabolism | Zebrafish - embryology | Semicircular Canals - cytology | Brain - metabolism | Vestibule, Labyrinth - cytology | Semicircular Canals - embryology | Otolithic Membrane - cytology | Otolithic Membrane - embryology | Base Sequence | Extracellular Matrix Proteins - isolation & purification | Vestibule, Labyrinth - embryology | Protein Biosynthesis - genetics | Minerals - metabolism | Extracellular Matrix Proteins - metabolism | Amino Acid Sequence | Brain - cytology | Zebrafish Proteins - metabolism | Extracellular Matrix Proteins - genetics | RNA, Messenger - genetics | Sequence Homology, Nucleic Acid | Down-Regulation - genetics | Zebrafish - genetics | Sequence Homology, Amino Acid | Animals | Zebrafish - metabolism | Zebrafish Proteins - isolation & purification | Zebrafish Proteins - genetics | Semicircular Canals - metabolism
Journal Article
Journal Article
Journal Article
ZOOLOGY-ANALYSIS OF COMPLEX SYSTEMS, ISSN 0944-2006, 1998, Volume 101, Issue 2, pp. 83 - 93
A number of specific molecular cues play important roles in guiding particular axons towards selected target locations in the nervous system. It is remarkable... 
GRASSHOPPER EMBRYOS | NERVOUS-SYSTEM | GENETIC-ANALYSIS | GROWTH CONE GUIDANCE | grasshopper | SUBCOMMISSURAL ORGAN | SPINAL-CORD | Reissner's substance | neuronal differentiation | ZOOLOGY | FLOOR PLATE | COMMISSURAL AXONS | NEURONAL AGGREGATION | C-ELEGANS | midline | extracellular matrix | Neuronal differentiation | Extracellular matrix | Midline | Grasshopper
Journal Article
Frontiers in Zoology, ISSN 1742-9994, 2009, Volume 6, Issue 1, pp. 11 - 11
Background: Echinoderms and chordates belong to the same monophyletic taxon, the Deuterostomia. In spite of significant differences in body plan organization,... 
REISSNERS FIBER | EVOLUTION | ZOOLOGY | FLOOR PLATE | HYDROCEPHALUS | SCO-SPONDIN | ULTRASTRUCTURE | SUBCOMMISSURAL ORGAN | ASTERIAS-RUBENS | NEURONAL AGGREGATION | DOGFISH SCYLIORHINUS-CANICULA | Physiological aspects | Evolution | Research | Natural history | Central nervous system | Deuterostomia
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 2001, Volume 107, Issue 1, pp. 47 - 61
The subcommissural organ (SCO) is an enigmatic secretory gland of the brain, which is believed to be derived from ependymal (glial) precursor cells. We here... 
Rat (wistar) | Cell culture | Explant culture | Bovine | Subcommissural organ | Organ culture | RAT PINEALOCYTES | explant culture | HYDROCEPHALUS | SCO-SPONDIN | TISSUE | BIOCHEMICAL RESEARCH METHODS | NEUROSCIENCES | subcommissural organ | SUB-COMMISSURAL ORGAN | RF | cell culture | BROMODEOXYURIDINE | organ culture | bovine | CHOROID-PLEXUS | rat (wistar) | MONOCLONAL-ANTIBODIES | REISSNERS FIBER COMPLEX | Immunohistochemistry | Calcium - metabolism | Cells, Cultured - cytology | Subcommissural Organ - metabolism | Cyclic AMP Response Element-Binding Protein - drug effects | Adenosine Triphosphate - pharmacology | Neuroglia - cytology | Cattle | Bodily Secretions - physiology | Cell Adhesion Molecules, Neuronal - metabolism | Subcommissural Organ - drug effects | Cell Culture Techniques | Phosphorylation - drug effects | Cell Differentiation - physiology | Cell Survival - physiology | Cell Survival - drug effects | Cells, Cultured - drug effects | Subcommissural Organ - cytology | Colforsin - pharmacology | Cell Size - physiology | Cell Division - drug effects | Cell Division - physiology | Animals | Cyclic AMP - biosynthesis | Cell Differentiation - drug effects | Bromodeoxyuridine - pharmacokinetics | Cyclic AMP Response Element-Binding Protein - metabolism | Neuroglia - metabolism | Cells, Cultured - metabolism | Cell Adhesion Molecules, Neuronal - immunology
Journal Article
Cilia, ISSN 2046-2530, 09/2013, Volume 2, Issue 1, p. 12
Circulation of cerebrospinal fluid (CSF) through the ventricular system is driven by motile cilia on ependymal cells of the brain. Disturbed ciliary motility... 
Choroid plexus | Xenopus | Brain | Cerebrospinal fluid flow | Hydrocephalus | Foxj1 | Reissner's fiber | Subcommissural organ | Cilia | Zona limitans intrathalamica | Motility | Cilia and ciliary motion | Analysis | Cerebrospinal fluid | Gene expression | Biological markers | Cells
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e93179
In mammals, the limited regenerating potential of the central nervous system (CNS) in adults contrasts with the plasticity of the embryonic and perinatal... 
REISSNERS FIBER | POTENT ACTIVITY | NEURONAL DEVELOPMENT | NEURITE OUTGROWTH | MULTIDISCIPLINARY SCIENCES | TIRILAZAD MESYLATE | CONTUSION MODEL | SUBCOMMISSURAL ORGAN | PLACING REACTIONS | TYPE-1 REPEAT TSR | RANDOMIZED CONTROLLED-TRIAL | Neuroprotective Agents - therapeutic use | Neurons - pathology | Cell Adhesion Molecules, Neuronal - chemistry | Neuroprotective Agents - chemistry | Spinal Cord Injuries - drug therapy | Recovery of Function - drug effects | Hydrogen Peroxide - pharmacology | Rats | Peptide Fragments - pharmacology | Spinal Cord Injuries - pathology | Neurites - pathology | Peptide Fragments - chemistry | Animals | Neuroprotective Agents - pharmacology | Cell Line, Tumor | Female | Neurogenesis - drug effects | Peptide Fragments - therapeutic use | Spinal Cord Injuries - physiopathology | Neurons - drug effects | Neurites - drug effects | Peptides | Analysis | Spinal cord injuries | Neuroprotection | Oxidative stress | Neurosciences | Animal models | Spinal cord | Hydrogen peroxide | Laboratories | Central nervous system | Recovery of function | Nervous system | Neuroblastoma | Spinal cord injury | Recovery | Neuroblastoma cells | Oxidation resistance | Blood-brain barrier | Rodents | Thrombospondin | Regrowth | Substantia alba | Embryos | Plasticity (axonal) | Studies | Regeneration | Injury prevention | Lymphocytes B | Collagen | In vivo methods and tests | Adults | Subcommissural organ | Viability | Apoptosis | Life Sciences | Neurons and Cognition | Neurobiology
Journal Article