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Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 06/2013, Volume 83, Issue 6, pp. 1029 - 1041
Oxidative stress and inflammation are mediators in the development and progression of chronic kidney disease (CKD) and its complications, and they are... 
ESRD | cardiovascular disease | CKD progression | inflammation | antioxidant therapy | oxidative stress | Oxidative stress | Cardiovascular disease | Antioxidant therapy | Inflammation | CYTOPROTECTIVE GENES | GLUTATHIONE SYNTHESIS | CARBON-MONOXIDE | AORTIC COARCTATION | REVERSE CHOLESTEROL TRANSPORT | BARDOXOLONE METHYL | CYCLOPENTENONE PROSTAGLANDINS | DENSITY-LIPOPROTEIN | UROLOGY & NEPHROLOGY | HEME OXYGENASE-1 | RENAL INJURY | Humans | Oleanolic Acid - analogs & derivatives | Kidney - immunology | NF-E2-Related Factor 2 - agonists | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - metabolism | Inflammation - metabolism | Kidney - metabolism | Time Factors | Inflammation - drug therapy | Renal Insufficiency, Chronic - diagnosis | Acute Kidney Injury - immunology | Inflammation - diagnosis | Oleanolic Acid - therapeutic use | Kidney Failure, Chronic - immunology | Kidney - drug effects | Renal Insufficiency, Chronic - immunology | Acute Kidney Injury - drug therapy | Kidney Failure, Chronic - drug therapy | Anti-Infective Agents - therapeutic use | Treatment Outcome | Inflammation - immunology | Disease Progression | Kidney Failure, Chronic - metabolism | Antioxidants - therapeutic use | Animals | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Acute Kidney Injury - metabolism | bardoxolone methyl
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2013, Volume 123, Issue 9, pp. 4023 - 4035
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2012, Volume 122, Issue 7, pp. 2543 - 2553
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with secondary hyperparathyroidism (HPT) and serum elevations in the phosphaturic... 
MEDICINE, RESEARCH & EXPERIMENTAL | FAMILIAL TUMORAL CALCINOSIS | VITAMIN-D METABOLISM | CARDIOVASCULAR EVENTS | VASCULAR CALCIFICATION | HEMODIALYSIS-PATIENTS | PARATHYROID-HORMONE | PHYSIOLOGICAL-ROLE | FIBROBLAST GROWTH FACTOR-23 | LEFT-VENTRICULAR HYPERTROPHY | STAGE RENAL-DISEASE | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Kidney - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Hyperparathyroidism, Secondary - physiopathology | Male | Chronic Kidney Disease-Mineral and Bone Disorder - metabolism | Parathyroid Hormone - blood | Tibia - pathology | Fibroblast Growth Factors - immunology | Luciferases - genetics | Renal Insufficiency, Chronic - metabolism | Calcium - blood | Fibroblast Growth Factors - metabolism | Phosphates - blood | Tibia - metabolism | Genes, Reporter | Kidney - physiopathology | CHO Cells | Biomarkers - metabolism | Cricetinae | Hyperparathyroidism, Secondary - metabolism | Glomerular Filtration Rate | Rats | Myocardium - pathology | Vascular Calcification - pathology | Calcitriol - blood | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - physiopathology | Aorta - pathology | Renal Insufficiency, Chronic - blood | Hyperparathyroidism, Secondary - blood | Animals | Mice | Mice, Inbred BALB C | Fibroblast Growth Factors - antagonists & inhibitors | Hemodynamics | Antibodies, Monoclonal, Murine-Derived - pharmacology | Luciferases - biosynthesis | Complications and side effects | United States | Mortality | Research | Kidney diseases | Hyperparathyroidism | Risk factors
Journal Article
Kidney International, ISSN 0085-2538, 03/2018, Volume 93, Issue 3, pp. 568 - 579
Renal tubules are the major component of the kidney and are vulnerable to a variety of injuries including hypoxia, proteinuria, toxins, metabolic disorders,... 
chronic kidney disease | acute kidney injury | renal fibrosis | renal tubule | renal inflammation | ACTIVATED PROTEIN-KINASE | CELL-CYCLE ARREST | GLOMERULAR EPITHELIAL-CELLS | ISCHEMIA-REPERFUSION INJURY | TO-MESENCHYMAL TRANSITION | TISSUE GROWTH-FACTOR | RENIN-ANGIOTENSIN SYSTEM | II-INDUCED HYPERTROPHY | UROLOGY & NEPHROLOGY | NF-KAPPA-B | PERICYTE-MYOFIBROBLAST TRANSITION | Cell Proliferation | Epithelial Cells - metabolism | Renal Insufficiency, Chronic - etiology | Humans | Renal Insufficiency, Chronic - metabolism | Acute Kidney Injury - complications | Epithelial-Mesenchymal Transition | Inflammation Mediators - metabolism | Acute Kidney Injury - immunology | Kidney Tubules - pathology | Kidney Tubules - metabolism | Cytokines - immunology | Inflammation Mediators - immunology | Kidney Tubules - immunology | Renal Insufficiency, Chronic - immunology | Cytokines - metabolism | Signal Transduction | Acute Kidney Injury - pathology | Cell Cycle Proteins - metabolism | Epithelial Cells - pathology | Immunity, Innate | Disease Progression | Renal Insufficiency, Chronic - pathology | Cell Cycle Checkpoints | Animals | Energy Metabolism | Epithelial Cells - immunology | Fibrosis | Acute Kidney Injury - metabolism | Senescence | Kidneys | Immune response | Mesenchyme | Epithelial cells | Inflammation | Epithelium | Drug development | Renal tubules | Cell death | Hypoxia | Metabolic disorders | Proteinuria
Journal Article
Kidney International, ISSN 0085-2538, 06/2013, Volume 83, Issue 6, pp. 1010 - 1016
Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are associated with systemic inflammation and acquired immunodeficiency, which promote... 
flora | malnutrition | cytokines | C-reactive protein | innate immunity | lipopo