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1. Full Text Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of interferon lambda against norovirus and reovirus
by Baldridge, Megan T and Lee, Sanghyun and Brown, Judy J and McAllister, Nicole and Urbanek, Kelly and Dermody, Terence S and Nice, Timothy J and Virgin, Herbert W
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 7
Lambda interferon (IFN-lambda) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and... 
Innate immunity | Mucosal immunity | Norovirus | Interferons | Reovirus | MURINE NOROVIRUS | PROTEIN | PERSISTENCE | RNA VIRUSES | PATHOGENESIS | interferons | REPLICATION | VIROLOGY | innate immunity | reovirus | norovirus | REVERSE GENETICS SYSTEM | IN-VIVO | INFECTION | MICE | mucosal immunity | Intestinal Mucosa - metabolism | Caliciviridae Infections - virology | Epithelial Cells - metabolism | Orthoreovirus, Mammalian - physiology | Virus Shedding | Reoviridae Infections - virology | Intestine, Large - metabolism | Intestinal Mucosa - immunology | Reoviridae Infections - metabolism | Caliciviridae Infections - immunology | Intestine, Small - immunology | Norovirus - physiology | Cell Line | Mice, Inbred C57BL | Reoviridae Infections - immunology | Intestine, Small - virology | Immunity, Innate | Organ Specificity | Intestine, Large - immunology | Mice, Knockout | Receptors, Interferon - metabolism | Animals | Intestine, Large - virology | Epithelial Cells - immunology | Epithelial Cells - virology | Caliciviridae Infections - metabolism | Mice | Intestine, Small - metabolism
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2. Full Text Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis
by Sharon K. Kuss and Gavin T. Best and Chris A. Etheredge and Andrea J. Pruijssers and Johnna M. Frierson and Lora V. Hooper and Terence S. Dermody and Julie K. Pfeiffer
Science, ISSN 0036-8075, 10/2011, Volume 334, Issue 6053, pp. 249 - 252
Intestinal bacteria aid host health and limit bacterial pathogen colonization. However, the influence of bacteria on enteric viruses is largely unknown. We... 
Microbiota | Microorganisms | Antibiotics | Pathogenesis | REPORTS | Viruses | Bacteria | Infections | Feces | Poliovirus | Reoviridae | MULTIDISCIPLINARY SCIENCES | HUMAN POLIOVIRUS RECEPTOR | TRANSGENIC MICE | Poliovirus - metabolism | Mammalian orthoreovirus 3 - physiology | Humans | Mice, Inbred C57BL | Cells, Cultured | Lipopolysaccharides - metabolism | Molecular Sequence Data | Bacterial Physiological Phenomena | Virus Shedding | Reoviridae Infections - virology | Feces - microbiology | Feces - virology | Animals | Intestines - microbiology | Virus Replication | Poliovirus - physiology | Intestines - virology | Poliomyelitis - virology | Anti-Bacterial Agents - pharmacology | Mice | HeLa Cells | Metagenome | Poliovirus - pathogenicity | Virus diseases | Disease transmission | Enterobacter | Microbiota (Symbiotic organisms) | Physiological aspects | Development and progression | Health aspects | Enterobacteriaceae | Small intestine | Rodents | Mucous membrane | Viral infections
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3. Full Text Infection experiments with novel Piscine orthoreovirus from rainbow trout (Oncorhynchus mykiss) in salmonids
by Hauge, Helena and Vendramin, Niccolo and Taksdal, Torunn and Olsen, Anne Berit and Wessel, Øystein and Mikkelsen, Susie Sommer and Alencar, Anna Luiza Farias and Olesen, Niels Jørgen and Dahle, Maria Krudtaa
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180293
A new disease in farmed rainbow trout (Onchorhyncus mykiss) was described in Norway in 2013. The disease mainly affected the heart and resembled heart and... 
HEART | REOVIRUS PRV | PANCREATIC-NECROSIS-VIRUS | ERYTHROCYTES | SALAR L | MULTIDISCIPLINARY SCIENCES | JUNCTIONAL ADHESION MOLECULE | DISEASE | TRANSCRIPTION | ATLANTIC SALMON | SKELETAL-MUSCLE INFLAMMATION | Orthoreovirus - pathogenicity | Virulence | Reoviridae Infections - virology | Fish Proteins - genetics | Salmo salar - virology | Reoviridae Infections - transmission | RNA, Viral - genetics | Muscle, Skeletal - virology | Oncorhynchus mykiss - virology | Salmo salar - blood | Gene Expression | Heart - virology | Orthoreovirus - genetics | Oncorhynchus mykiss - genetics | Fish Diseases - transmission | Reverse Transcriptase Polymerase Chain Reaction | Fish Proteins - blood | Oncorhynchus mykiss - blood | Salmo salar - genetics | Host-Pathogen Interactions | Animals | Fish Diseases - virology | Norway | Denmark | Orthoreovirus - physiology | Reoviridae Infections - diagnosis | Fish Diseases - diagnosis | Hemoglobins - analysis | Virus diseases | RNA viruses | Diseases and pests | Rainbow trout | Physiological aspects | Development and progression | Research | Heart | Epidemics | Similarity | Disease | Pathogenesis | Viruses | Infections | Genomes | Experiments | Blood | Genetic relationship | Proteins | Risk assessment | Gangrene | Fish | Salmonids | Heart diseases | Spleen | Cardiac muscle | Salmon | Anemia | Trout | Inflammation | RNA polymerase | Gene expression | Coronary artery disease | Skeletal muscle | Virology | Studies | Myocarditis | Musculoskeletal system | Diagnostic systems
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4. Full Text A multiplex xTAG assay for the simultaneous detection of five chicken immunosuppressive viruses
by Cong, F and Zhu, YJ and Wang, J and Lian, YX and Liu, XN and Xiao, L and Huang, R and Zhang, Y and Chen, ML and Guo, PJ
BMC VETERINARY RESEARCH, ISSN 1746-6148, 11/2018, Volume 14, Issue 1, pp. 347 - 8
Background: Chicken anemia virus (CAV), avian reovirus (ARV), infectious bursal disease virus (IBDV), Marek's disease virus (MDV) and reticuloendotheliosis... 
TRANSFORMATION | Multiplex xTAG assay | Simultaneous detection | Chicken immunosuppressive viruses | ANEMIA VIRUS | MAREKS-DISEASE | Avian reovirus | RETICULOENDOTHELIOSIS VIRUS | AGENT | Chicken anemia virus | REPLICATION | GENE | INFECTIOUS BURSAL DISEASE | VETERINARY SCIENCES | PCR | Birnaviridae Infections - diagnosis | Circoviridae Infections - veterinary | Retroviridae Infections - virology | Tumor Virus Infections - virology | Marek Disease - diagnosis | Chickens - virology | Circoviridae Infections - diagnosis | Tumor Virus Infections - diagnosis | Reticuloendotheliosis Viruses, Avian | Mardivirus | Reoviridae Infections - virology | Marek Disease - virology | Microarray Analysis - veterinary | Infectious bursal disease virus | Sensitivity and Specificity | Coinfection - veterinary | Retroviridae Infections - veterinary | Microarray Analysis - methods | Multiplex Polymerase Chain Reaction - methods | Reproducibility of Results | Tumor Virus Infections - veterinary | Circoviridae Infections - virology | Orthoreovirus, Avian | Poultry Diseases - diagnosis | Retroviridae Infections - diagnosis | Reoviridae Infections - veterinary | Poultry Diseases - virology | Coinfection - virology | Birnaviridae Infections - veterinary | Birnaviridae Infections - virology | Animals | Coinfection - diagnosis | Multiplex Polymerase Chain Reaction - veterinary | Reoviridae Infections - diagnosis | Virus diseases | Chickens | Immunologic diseases | Diagnosis | Assaying | Methods | Veterinary immunology | Diseases | Multiplexing | Poultry | Fluorescence | Viruses | Infections | Epidemiology | Avian flu | Bronchitis | Public health | Deoxyribonucleic acid--DNA | Pathogens | Polystyrene resins | Infectious bursal disease | Anemia | Birds | Laryngotracheitis | Polystyrene | Virology | Polymerase chain reaction | Newcastle disease | Immunosuppression | Infectious diseases | Disease transmission | Influenza | Viral infections
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5. Full Text Efficient norovirus and reovirus replication in the mouse intestine requires microfold (M) cells
by Gonzalez-Hernandez, Mariam B and Liu, Thomas and Payne, Hilary C and Stencel-Baerenwald, Jennifer E and Ikizler, Mine and Yagita, Hideo and Dermody, Terence S and Williams, Ifor R and Wobus, Christiane E
Journal of Virology, ISSN 0022-538X, 2014, Volume 88, Issue 12, pp. 6934 - 6943
Microfold (M) cells are specialized intestinal epithelial cells that internalize particulate antigens and aid in the establishment of immune responses to... 
SHIGELLA-FLEXNERI | MURINE NOROVIRUS | MICROBIAL PATHOGENESIS | VIROLOGY | PEYERS-PATCHES | EPITHELIAL M-CELLS | ATTACHMENT RECEPTORS | SALMONELLA-TYPHIMURIUM | SIALIC-ACID | PATCH DENDRITIC CELLS | REVERSE GENETICS | Norovirus - physiology | Cell Line | Caliciviridae Infections - virology | Humans | Reoviridae Infections - virology | Animals | Reoviridae - physiology | Virus Replication | Epithelial Cells - virology | Intestines - virology | Mice | Mice, Inbred BALB C | Intestines - cytology | Pathogenesis and Immunity
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6. Full Text Piscine orthoreovirus from western North America is transmissible to atlantic salmon and sockeye salmon but fails to cause heart and skeletal muscle inflammation
by Garver, Kyle A and Johnson, Stewart C and Polinski, Mark P and Bradshaw, Julia C and Marty, Gary D and Snyman, Heindrich N and Morrison, Diane B and Richard, Jon
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0146229
Heart and skeletal muscle inflammation (HSMI) is a significant and often fatal disease of cultured Atlantic salmon in Norway. The consistent presence of... 
REOVIRUS PRV | VIRUS | OUTBREAK | SALAR L | BRITISH-COLUMBIA | MULTIDISCIPLINARY SCIENCES | Prevalence | Molecular Sequence Data | RNA, Viral - blood | Phylogeny | Reoviridae Infections - virology | Orthoreovirus - classification | Endemic Diseases | Salmo salar - virology | Reoviridae Infections - transmission | RNA, Viral - genetics | Reoviridae Infections - epidemiology | Time Factors | Muscle, Skeletal - virology | RNA, Viral - metabolism | Salmo salar - blood | Amino Acid Sequence | Orthoreovirus - genetics | Fish Diseases - epidemiology | Fish Diseases - transmission | Host-Pathogen Interactions | Sequence Homology, Amino Acid | Animals | Cardiomyopathies - virology | Fish Diseases - virology | Myositis - virology | Orthoreovirus - physiology | Muscle, Skeletal - pathology | North America - epidemiology | Antiviral agents | Salmon | Analysis | Muscles | Physiological aspects | Inflammation | Research | Health aspects | Heart | Cohabitation | Epidemics | Disease | Transcription | Laboratories | Cardiomyopathy | Viruses | Blood | Etiology | Infectivity | Peripheral blood | Fish | Lesions | Kidneys | Cardiac muscle | Anemia | Causation | Fisheries | Ribonucleic acid--RNA | Skeletal muscle | Virology | Studies | Musculoskeletal system | Fish diseases | Comparative analysis | Aquaculture | Farming | RNA | Ribonucleic acid
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7. Full Text Isolation and identification of bat viruses closely related to human, porcine and mink orthoreoviruses
by Yang, Xing-Lou and Tan, Bing and Wang, Bo and Li, Wen and Wang, Ning and Luo, Chu-Ming and Wang, Mei-Niang and Zhang, Wei and Li, Bei and Peng, Cheng and Ge, Xing-Yi and Zhang, Li-Biao and Shi, Zheng-Li
Journal of General Virology, ISSN 0022-1317, 12/2015, Volume 96, Issue 12, pp. 3525 - 3531
Bats have been identified as natural reservoirs of many viruses, including reoviruses. Recent studies have demonstrated the interspecies transmission of bat... 
TYPE-3 | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SEQUENCE | REOVIRUS | CHILD | FRUIT BATS | MEMBER | Chiroptera - virology | Disease Reservoirs - virology | Humans | Orthoreovirus, Mammalian - genetics | Serogroup | Reoviridae Infections - veterinary | China - epidemiology | Phylogeny | Reoviridae Infections - virology | Reoviridae Infections - transmission | Animals | Reoviridae Infections - epidemiology | Orthoreovirus, Mammalian - isolation & purification | Orthoreovirus, Mammalian - classification | Swine - virology | Mink - virology
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8. Full Text Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in heart of Atlantic salmon (Salmo salar L)
by Johansen, Lill-Heidi and Thim, Hanna L and Jørgensen, Sven Martin and Jørgensen, Jorunn B and Afanasyev, Sergey and Strandskog, Guro and Taksdal, Torunn and Fremmerlid, Kjersti and McLoughlin, Marion and Krasnov, Aleksei
Fish and Shellfish Immunology, ISSN 1050-4648, 10/2015, Volume 46, Issue 2, pp. 612 - 623
Pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) are viral diseases associated with SAV (salmonid alphavirus) and PRV (piscine... 
Heart | Transcriptomic responses | Immune genes | Pancreas disease | Atlantic salmon | Heart and skeletal muscle inflammation | ANEMIA-VIRUS | NECROSIS VIRUS | PISCINE REOVIRUS PRV | ONCORHYNCHUS-MYKISS | IMMUNOLOGY | HOST RESPONSE | POST-SMOLTS | FISHERIES | IMMUNE-RESPONSES | ALPHAVIRUS SAV | MARINE & FRESHWATER BIOLOGY | GENE-EXPRESSION | NATURAL OUTBREAK | VETERINARY SCIENCES | Pancreatic Diseases - veterinary | Myocardium - immunology | Heart Diseases - veterinary | Down-Regulation | Reoviridae Infections - immunology | Salmo salar | Inflammation - virology | Inflammation - immunology | Reoviridae Infections - veterinary | Alphavirus Infections - immunology | Reoviridae Infections - virology | Heart Diseases - virology | Inflammation - veterinary | Pancreatic Diseases - immunology | Alphavirus Infections - virology | Animals | Fish Diseases - virology | Reoviridae - physiology | Myocardium - metabolism | Alphavirus Infections - veterinary | Fish Diseases - immunology | Alphavirus - physiology | Pancreatic Diseases - virology | Heart Diseases - immunology
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9. Full Text Heart and skeletal muscle inflammation (HSMI) disease diagnosed on a British Columbia salmon farm through a longitudinal farm study
by Di Cicco, Emiliano and Ferguson, Hugh W and Schulze, Angela D and Kaukinen, Karia H and Li, Shaorong and Vanderstichel, Raphaël and Wessel, Øystein and Rimstad, Espen and Gardner, Ian A and Hammell, K. Larry and Miller, Kristina M
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0171471
Heart and skeletal muscle inflammation (HSMI) is an emerging disease of marine-farmed Atlantic Salmon (Salmo salar), first recognized in 1999 in Norway, and... 
REOVIRUS PRV | WILD | PISCINE-ORTHOREOVIRUS PRV | SALAR L | MULTIDISCIPLINARY SCIENCES | CARDIOMYOPATHY | MYOCARDITIS | PANCREAS DISEASE | ATLANTIC SALMON | Reoviridae Infections - pathology | Inflammation - pathology | Inflammation - virology | Cardiomyopathies - pathology | Fisheries | British Columbia | Reoviridae Infections - veterinary | Reoviridae Infections - virology | Fish Diseases - pathology | Salmo salar - virology | Inflammation - veterinary | Animals | Cardiomyopathies - virology | Fish Diseases - virology | Cardiomyopathies - veterinary | Longitudinal Studies | Immunohistochemistry | Salmon | Muscles | Physiological aspects | Inflammation | Diagnosis | Research | Health aspects | Heart | Epidemics | Veterinary colleges | Disease | Pathogenesis | Erythrocytes | Staining | Viruses | Population studies | Statistical methods | Parasites | Veterinary medicine | Fishing | Red blood cells | Farms | Animal tissues | Gangrene | Fish | Life sciences | Lesions | Heart diseases | Evaluation | Statistical analysis | Cardiac muscle | Mortality | Blood cells | Cardiomyocytes | Skeletal muscle | Musculoskeletal system | Correlation analysis | Food safety
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10. Full Text Quantitative in vivo and in vitro characterization of co-infection by two genetically distant grass carp reoviruses
by Wang, Tu and Li, Jiale and Lu, Liqun
Journal of General Virology, ISSN 0022-1317, 06/2013, Volume 94, Issue 6, pp. 1301 - 1309
Grass carp reovirus (GCRV) is one of the most serious pathogens threatening grass carp (Ctenopharyngodon idella) production in China. Through sequence... 
FAMILY REOVIRIDAE | VIRION | VIRUS | ASSAY | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENUS AQUAREOVIRUS | SEQUENCE | GENOME | Reoviridae - genetics | Molecular Sequence Data | Reoviridae Infections - veterinary | Phylogeny | Coinfection - virology | Reoviridae Infections - virology | Carps - virology | Animals | Fish Diseases - virology | Reoviridae - physiology | China | Reoviridae - isolation & purification | Coinfection - veterinary | Reoviridae - classification
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11. Full Text The Nogo Receptor NgR1 Mediates Infection by Mammalian Reovirus
by Konopka-Anstadt, Jennifer L and Mainou, Bernardo A and Sutherland, Danica M and Sekine, Yuichi and Strittmatter, Stephen M and Dermody, Terence S
Cell Host & Microbe, ISSN 1931-3128, 06/2014, Volume 15, Issue 6, pp. 681 - 691
Neurotropic viruses, including mammalian reovirus, must disseminate from an initial site of replication to the central nervous system (CNS), often binding... 
HOST FACTORS | AXONAL REGENERATION | MICROBIOLOGY | MYELIN-ASSOCIATED GLYCOPROTEIN | PATHOGENESIS | PERSISTENT INFECTIONS | INHIBITION | VIROLOGY | NEURITE OUTGROWTH | JUNCTIONAL ADHESION MOLECULE | CENTRAL-NERVOUS-SYSTEM | SPINAL-CORD-INJURY | PARASITOLOGY | Cell Adhesion Molecules - genetics | Reoviridae - metabolism | Cricetulus | Humans | Reoviridae Infections - virology | Mice, Mutant Strains | Neuraminidase - chemistry | CHO Cells - virology | Cell Membrane - metabolism | Nogo Receptor 1 | Reoviridae Infections - metabolism | Neurons - virology | Capsid Proteins - metabolism | Receptors, Cell Surface - metabolism | Virion - metabolism | Cell Adhesion Molecules - metabolism | Myelin Proteins - genetics | GPI-Linked Proteins - metabolism | Host-Pathogen Interactions | Animals | Reoviridae - pathogenicity | Cell Membrane - virology | Myelin Proteins - metabolism | GPI-Linked Proteins - genetics | Receptors, Cell Surface - genetics | Health aspects | Neurosciences
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12. Full Text Rice dwarf virus infection alters green rice leafhopper host preference and feeding behavior
by Wang, Qianjin and Li, Jingjing and Dang, Cong and Chang, Xuefei and Fang, Qi and Stanley, David and Ye, Gongyin
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0203364
Host plants, pathogens and their herbivore vectors systems have complex relationships via direct and indirect interactions. Although there are substantial gaps... 
RESPONSES | MANIPULATION | PROTEIN | MYZUS-PERSICAE HOMOPTERA | MULTIDISCIPLINARY SCIENCES | DISEASE | PLANTS | MOSAIC-VIRUS | APHID | EPIDEMIOLOGY | INSECT VECTORS | Reoviridae - genetics | Hemiptera - physiology | Feeding Behavior | Host Specificity | Herbivory | Hemiptera - virology | Insect Vectors - virology | Reoviridae Infections - virology | Odorants | Hemiptera - pathogenicity | Oryza - virology | Reoviridae Infections - transmission | Animals | Host Microbial Interactions - physiology | Insect Vectors - physiology | Plant Diseases - virology | Insect Vectors - pathogenicity | Reoviridae - pathogenicity | Reoviridae Infections - parasitology | Electrophysiological Phenomena | Oryza - parasitology | Prevention | Epidemics | Plant diseases | Plant physiology | Analysis | Physiological aspects | Health aspects | Rice | Xylem | Laboratories | Viruses | Infections | Epidemiology | Odors | Arthropods | Behavior | Flowers & plants | Tomatoes | Plant viruses | Plants (botany) | Feeding behavior | Bioassay | Bioassays | Vectors | Feeding | Hypotheses | Penetration | Disease transmission | Insects | Host plants | Influence | Crop diseases | Molecular biology | Odor | Viral infections
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