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Science, ISSN 0036-8075, 3/2006, Volume 311, Issue 5767, pp. 1600 - 1603
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 273 - 277
The peroxisomal protein import machinery differs fundamentally from known translocons (endoplasmic reticulum, mitochondria, chloroplasts, bacteria) as it... 
RAT-LIVER | TRANSLOCATION | COMPLEX | INSERTION | CHANNEL | PROTEIN IMPORT | MITOCHONDRIAL INNER MEMBRANE | SACCHAROMYCES-CEREVISIAE | RECEPTOR PEX5P | PREPROTEINS | CELL BIOLOGY | Acyl-CoA Oxidase - metabolism | Protein Transport - physiology | Unilamellar Liposomes - chemistry | Ion Channels - physiology | Porins - analysis | Ubiquitin-Protein Ligases - physiology | Repressor Proteins - analysis | Membrane Proteins - analysis | Membrane Transport Proteins - physiology | Repressor Proteins - physiology | Ion Channel Gating - physiology | Membrane Proteins - physiology | Gene Deletion | Ubiquitin-Protein Ligases - analysis | Peroxins | Saccharomyces cerevisiae - physiology | Peroxisomes - physiology | Electrophysiological Phenomena - physiology | Membrane Transport Proteins - analysis | Membranes, Artificial | Receptors, Cytoplasmic and Nuclear - physiology | Saccharomyces cerevisiae Proteins - genetics | Membrane Potentials - physiology | Saccharomyces cerevisiae - chemistry | Multiprotein Complexes - physiology | Carrier Proteins - genetics | Multiprotein Complexes - chemistry | Models, Biological | Peroxisome-Targeting Signal 1 Receptor | Receptors, Cytoplasmic and Nuclear - analysis | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae Proteins - physiology | Saccharomyces cerevisiae Proteins - analysis | Porins - physiology | Multiprotein Complexes - isolation & purification | Physiological aspects | Cell receptors | Peroxisomes | Cell membranes | Genetic aspects | Research
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7399, pp. 507 - 511
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including Alzheimer's, Parkinson's and... 
UNFOLDED PROTEIN RESPONSE | TOXICITY IN-VIVO | ALZHEIMERS-DISEASE | ER STRESS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MICE | ENDOPLASMIC-RETICULUM STRESS | DYSFUNCTION | PRP | PROTEOSTASIS | Neurons - pathology | Neuroprotective Agents | Phosphorylation | Prions - genetics | Eukaryotic Initiation Factor-2 - chemistry | Neurodegenerative Diseases - etiology | PrPSc Proteins - analysis | Synapses - pathology | Thiourea - pharmacology | Phosphoproteins - metabolism | Repressor Proteins - analysis | PrPSc Proteins - metabolism | Synapses - metabolism | Phosphoproteins - analysis | Protein Folding - drug effects | Protein Phosphatase 1 - genetics | Eukaryotic Initiation Factor-2 - metabolism | Synaptic Transmission - drug effects | Cell Death - drug effects | PrPSc Proteins - toxicity | Neurons - drug effects | Repressor Proteins - metabolism | Prions - metabolism | Synapses - drug effects | Repressor Proteins - chemistry | Neurodegenerative Diseases - pathology | Mice, Inbred C57BL | Kaplan-Meier Estimate | Hippocampus - pathology | Prion Diseases - pathology | Neurodegenerative Diseases - metabolism | Hippocampus - cytology | Cinnamates - pharmacology | Eukaryotic Initiation Factor-2 - analysis | Hippocampus - metabolism | Protein Phosphatase 1 - metabolism | Animals | Prions - biosynthesis | Protein Biosynthesis - drug effects | Mice | Unfolded Protein Response - physiology | Thiourea - analogs & derivatives
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2006, Volume 12, Issue 7, pp. 2109 - 2116
Purpose: Aberrant promoter hypermethylation of Wnt-antagonist genes contributes to the pathogenesis of several cancers. We hypothesized that combined... 
secreted frizzled-related protein-1, 2, 4 and 5 | Wnt inhibitory factor-1 | Dickkopf family proteins-3 | bladder cancer | methylation | INACTIVATION | HUMAN PROSTATE-CANCER | PROMOTER HYPERMETHYLATION | SFRP GENES | METHYLATION | INHIBITORY FACTOR-I | ONCOLOGY | SIGNALING PATHWAY | COLORECTAL-CANCER | TUMOR-SUPPRESSOR GENES | URINE | Intercellular Signaling Peptides and Proteins - analysis | Multivariate Analysis | Carrier Proteins - urine | Urinary Bladder Neoplasms - diagnosis | Carcinoma, Transitional Cell - urine | Humans | Proto-Oncogene Proteins - urine | Membrane Proteins - urine | Repressor Proteins - analysis | Membrane Proteins - analysis | DNA Methylation | Urinary Bladder Neoplasms - genetics | Biomarkers, Tumor - urine | Proto-Oncogene Proteins - analysis | Sensitivity and Specificity | Eye Proteins - genetics | Carrier Proteins - analysis | Carcinoma, Transitional Cell - genetics | Repressor Proteins - urine | Urinary Bladder Neoplasms - urine | Biomarkers, Tumor - analysis | Membrane Proteins - genetics | Carcinoma, Transitional Cell - diagnosis | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Intercellular Signaling Peptides and Proteins - urine | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Eye Proteins - analysis | Reverse Transcriptase Polymerase Chain Reaction | Sequence Analysis, DNA | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Biomarkers, Tumor - genetics | Eye Proteins - urine | Urinary Bladder - physiology
Journal Article
Critical Care, ISSN 1364-8535, 06/2016, Volume 20, Issue 1, p. 170
Background: Whole body ischemia-reperfusion injury (IRI) after cardiopulmonary resuscitation (CPR) induces a generalized inflammatory response which... 
Post-cardiac arrest syndrome | Endotoxin tolerance | Inflammasome | Monocyte | Cardiopulmonary resuscitation | Toll-like receptor | IRAK-M | IMMUNE-RESPONSE | DOWN-REGULATION | NEUTROPHIL ELASTASE | CARDIAC-ARREST PATIENTS | AMERICAN-HEART-ASSOCIATION | CIRCULATING MONOCYTES | ENDOTHELIAL INJURY | EMERGENCY CARDIOVASCULAR CARE | CRITICAL CARE MEDICINE | Reperfusion Injury - etiology | Nuclear Proteins - analysis | Prospective Studies | Adaptor Proteins, Signal Transducing - blood | Humans | Middle Aged | Apoptosis Regulatory Proteins - analysis | Homeodomain Proteins - blood | DNA-Binding Proteins - analysis | Male | Monocytes - metabolism | Repressor Proteins - analysis | Interleukin-1beta - blood | Cytoskeletal Proteins - blood | Monocytes - pathology | Systemic Inflammatory Response Syndrome - prevention & control | Female | Reperfusion Injury - complications | Toll-Like Receptors - metabolism | Toll-Like Receptor 4 - analysis | Cytoskeletal Proteins - analysis | Interleukin-1beta - analysis | Nuclear Proteins - blood | Repressor Proteins - blood | NLR Family, Pyrin Domain-Containing 3 Protein - blood | Interleukin-1 Receptor-Associated Kinases - analysis | Inflammasomes - pharmacokinetics | Monocytes - chemistry | Adaptor Proteins, Signal Transducing - analysis | Toll-Like Receptor 4 - blood | Homeodomain Proteins - analysis | NLR Family, Pyrin Domain-Containing 3 Protein - analysis | CARD Signaling Adaptor Proteins | Toll-Like Receptor 2 - analysis | Toll-Like Receptor 2 - blood | Signal Transduction - physiology | Aged | Interleukin-1 Receptor-Associated Kinases - blood | DNA-Binding Proteins - blood | Cardiopulmonary Resuscitation - mortality | Germany | Apoptosis Regulatory Proteins - blood | Care and treatment | Interleukins | Influence | CPR (First aid) | Research | Coronary heart disease | Health aspects
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 6/2007, Volume 316, Issue 5831, pp. 1619 - 1622
Journal Article
Cell, ISSN 0092-8674, 06/2013, Volume 153, Issue 6, pp. 1281 - 1295
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 49, pp. 19226 - 19231
Journal Article
Analytical Chemistry, ISSN 0003-2700, 04/2003, Volume 75, Issue 7, pp. 1584 - 1589
In this study we developed an inducible synthetic renilla luciferase protein-fragment-assisted complementation-based bioluminescence assay to quantitatively... 
RENIFORMIS LUCIFERASE | LIVING SUBJECTS | CHEMISTRY, ANALYTICAL | BETA-GALACTOSIDASE COMPLEMENTATION | GREEN FLUORESCENT PROTEIN | MAMMALIAN-CELLS | EXPRESSION | RECONSTITUTION | RECRUITMENT SYSTEM | INTEIN | STRATEGIES | Proteins | Bioluminescence | Chemistry, Analytic | Tumor necrosis factor | Analysis | Causes of | Research | Cells | Organic compounds
Journal Article