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PLoS Pathogens, ISSN 1553-7366, 11/2012, Volume 8, Issue 11, p. e1003016
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 10008, pp. 2078 - 2088
Summary Background Despite preventive vaccines for oncogenic human papillomaviruses (HPVs), cervical intraepithelial neoplasia (CIN) is common, and current... 
Internal Medicine | REGRESSION | MEDICINE, GENERAL & INTERNAL | ELECTROPORATION | METHYLATION | INTEGRATION | IMMUNOTHERAPY | E2 BINDING-SITES | NATURAL-HISTORY | CANCER | BURDEN | EXPRESSION | Human papillomavirus 18 - immunology | Humans | Papillomavirus E7 Proteins - immunology | Vaccines, DNA - immunology | Cervical Intraepithelial Neoplasia - drug therapy | Human papillomavirus 16 - immunology | Papillomavirus E7 Proteins - genetics | Young Adult | Cancer Vaccines - therapeutic use | Adult | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Human papillomavirus 18 - genetics | DNA-Binding Proteins - immunology | Papillomavirus Vaccines - therapeutic use | Double-Blind Method | Repressor Proteins - genetics | Treatment Outcome | Uterine Cervical Neoplasms - drug therapy | Vaccines, DNA - therapeutic use | DNA-Binding Proteins - genetics | Cervical Intraepithelial Neoplasia - virology | Cancer Vaccines - immunology | Repressor Proteins - immunology | Papillomavirus Infections - drug therapy | Uterine Cervical Neoplasms - virology | Papillomavirus Vaccines - immunology | Oncogene Proteins, Viral - immunology | Human papillomavirus 16 - genetics | Proteins | Cervix dysplasia | DNA | Clinical trials | Product development | Vaccines | Health aspects | Papillomavirus infections | Medical research | Analysis | Medicine, Experimental | Human papillomavirus | Immunization | Womens health | Immunotherapy | Genomes | Cervical cancer | Deoxyribonucleic acid--DNA
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 12, pp. 2015 - 2025
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2015, Volume 21, Issue 19, pp. 4431 - 4439
Purpose: The E6 and E7 oncoproteins of HPV-associated epithelial cancers are in principle ideal immunotherapeutic targets, but evidence that T cells specific... 
REGRESSION | RESPONSES | THERAPY | EPITOPE | ONCOLOGY | VACCINATION | CERVICAL-CANCER | NAIVE RATHER | HUMAN-PAPILLOMAVIRUS | CARCINOMA | ANTIGEN | Recombinant Fusion Proteins - immunology | T-Lymphocyte Subsets - immunology | Dendritic Cells - immunology | Humans | Epitopes, T-Lymphocyte - genetics | Human papillomavirus 16 - immunology | Carcinoma - etiology | Neoplasm Metastasis | T-Cell Antigen Receptor Specificity - immunology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Oncogene Proteins, Viral - genetics | Epitopes, T-Lymphocyte - immunology | Genes, T-Cell Receptor | Dendritic Cells - metabolism | Repressor Proteins - metabolism | Oncogene Proteins, Viral - metabolism | Gene Expression | Transduction, Genetic | HLA-A2 Antigen - immunology | Repressor Proteins - genetics | Anus Neoplasms - pathology | Cross Reactions - immunology | Protein Binding - immunology | Lymphocytes, Tumor-Infiltrating - pathology | T-Lymphocyte Subsets - metabolism | Repressor Proteins - immunology | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Uterine Cervical Neoplasms - etiology | Carcinoma - therapy | Oncogene Proteins, Viral - immunology | Anus Neoplasms - etiology | Carcinoma - metabolism | HLA-A2 Antigen - metabolism | Human papillomavirus 16 - genetics | Lymphocytes, Tumor-Infiltrating - immunology | T-cell receptor | oropharyneal cancer | T cell | human papillomavirus | gene therapy | anal cancer | adoptive cell therapy | cervical cancer
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 708 - 717
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 05/2011, Volume 208, Issue 5, pp. 1001 - 1013
The T-box transcription factor T-bet is important for the differentiation of naive CD4(+) T helper cells (Th cells) into the Th1 phenotype. Much is known about... 
MEDICINE, RESEARCH & EXPERIMENTAL | SUPPRESSOR | TARGET GENES | COMMITMENT | INTERFERON-GAMMA | CYTOKINE SIGNALING-1 | SOCS-3 | IMMUNOLOGY | TRANSCRIPTION FACTOR GATA-3 | CELL-DIFFERENTIATION | FATE | PLASTICITY | Genetic Loci - genetics | Suppressor of Cytokine Signaling 1 Protein | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Genetic Loci - immunology | Th1 Cells - metabolism | Cell Differentiation - genetics | Proto-Oncogene Proteins c-bcl-6 - metabolism | Response Elements - genetics | T Cell Transcription Factor 1 - metabolism | Repressor Proteins - metabolism | Cell Line | Suppressor of Cytokine Signaling Proteins - immunology | Hepatocyte Nuclear Factor 1-alpha | Repressor Proteins - genetics | Suppressor of Cytokine Signaling Proteins - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Response Elements - immunology | T-Box Domain Proteins - metabolism | Mice, Knockout | T Cell Transcription Factor 1 - genetics | Proto-Oncogene Proteins c-bcl-6 - genetics | Autoimmunity - physiology | Cell Differentiation - immunology | Suppressor of Cytokine Signaling 3 Protein | Animals | Down-Regulation - immunology | Repressor Proteins - immunology | T Cell Transcription Factor 1 - immunology | Transcription, Genetic - immunology | Mice | Th1 Cells - cytology | Suppressor of Cytokine Signaling Proteins - metabolism | Transcription, Genetic - genetics | Proto-Oncogene Proteins c-bcl-6 - immunology
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2006, Volume 7, Issue 2, pp. 148 - 155
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 12, pp. 2041 - 2056
The transcription factor T-bet is critical for cytotoxic T lymphocyte (CTL) differentiation, but it is unclear how it operates in a graded manner in the... 
EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | PROTECTIVE IMMUNITY | STEM-CELLS | SELECTIVE EXPRESSION | MEMORY | GENE | IN-VIVO | SUBSETS | GENERATION | IMMUNOLOGY | CUTTING EDGE | Lymphocytic choriomeningitis virus - immunology | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - immunology | T-Box Domain Proteins - immunology | Transcriptome - immunology | Lymphocytic Choriomeningitis - immunology | Zinc Finger E-box Binding Homeobox 2 | Host-Pathogen Interactions - immunology | Cell Differentiation - genetics | Flow Cytometry | Repressor Proteins - deficiency | CD8-Positive T-Lymphocytes - metabolism | Lymphocytic choriomeningitis virus - physiology | Receptors, Immunologic - immunology | Lymphocytic Choriomeningitis - genetics | T-Lymphocytes, Cytotoxic - immunology | Lymphocytic Choriomeningitis - virology | Mice, Inbred C57BL | Repressor Proteins - genetics | Mice, Transgenic | Transcriptome - genetics | Protein Binding - immunology | Reverse Transcriptase Polymerase Chain Reaction | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | Cell Differentiation - immunology | Animals | T-Lymphocytes, Cytotoxic - metabolism | Repressor Proteins - immunology | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - metabolism | Cluster Analysis
Journal Article
Science, ISSN 0036-8075, 04/2017, Volume 356, Issue 6334, pp. 200 - 205
Immunotherapy has clinical activity in certain virally associated cancers. However, the tumor antigens targeted in successful treatments remain poorly defined.... 
TRIAL | CELLS | THERAPY | KK-LC-1 | RECURRENT | MULTIDISCIPLINARY SCIENCES | CERVICAL-CANCER | IDENTIFICATION | BLOCKADE | CARCINOMA | LYMPHOCYTES | Human papillomavirus 18 - immunology | Carcinoma, Squamous Cell - virology | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Human papillomavirus 16 - immunology | T-Lymphocytes - transplantation | Papillomavirus Infections - therapy | Female | Oncogene Proteins, Viral - genetics | Uterine Cervical Neoplasms - therapy | Antigens, Neoplasm - genetics | Immunotherapy, Adoptive - methods | Papillomavirus Infections - complications | DNA-Binding Proteins - immunology | Antigens, Neoplasm - immunology | Carcinoma, Squamous Cell - therapy | Lymphocytes, Tumor-Infiltrating - transplantation | Programmed Cell Death 1 Receptor - metabolism | Repressor Proteins - genetics | DNA-Binding Proteins - genetics | Repressor Proteins - immunology | Uterine Cervical Neoplasms - virology | T-Lymphocytes - immunology | Oncogene Proteins, Viral - immunology | Programmed Cell Death 1 Receptor - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Antigens | Care and treatment | Health aspects | Immunotherapy | Methods | Cancer | Human papillomavirus | Immune response | Lymphocytes | Cell death | T cell receptors | Lymphocytes T | Immune system | Tumors | Harnesses | Landscapes | Regression | Strategy | Human behavior
Journal Article