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Journal Article
Psychopharmacology, ISSN 0033-3158, 12/2008, Volume 201, Issue 3, pp. 435 - 442
Journal Article
Neuron, ISSN 0896-6273, 2004, Volume 42, Issue 6, pp. 939 - 946
Synchronous activation of dopamine neurons, for instance upon presentation of an unexpected rewarding stimulus, results in the release of dopamine from both... 
SYNAPTIC INPUTS | SUBSTANTIA-NIGRA NEURONS | DENDRO-DENDRITIC SYNAPSES | POTASSIUM CHANNELS | QUANTAL SIZE | FIRING PATTERN | MEMBRANE-PROPERTIES | DEFICIENT MICE | NEUROSCIENCES | MEDIATED VOLUME TRANSMISSION | VENTRAL TEGMENTAL AREA | Sulpiride - pharmacology | G Protein-Coupled Inwardly-Rectifying Potassium Channels | Mesencephalon - cytology | Calcium - metabolism | Male | Dose-Response Relationship, Drug | Dopamine Agents - pharmacology | Neurons - physiology | Organophosphorus Compounds - pharmacology | Reserpine - pharmacology | Female | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Action Potentials - drug effects | Dopamine - metabolism | Levodopa - pharmacology | Dopamine Uptake Inhibitors - pharmacology | Mice, Inbred C57BL | Potassium Channels, Inwardly Rectifying | Sodium Channel Blockers - pharmacology | Iontophoresis - methods | Calcium Channel Blockers - pharmacology | Receptors, Dopamine D2 - genetics | GABA Antagonists - pharmacology | Mice, Knockout | Potassium Channels - genetics | Cocaine - pharmacology | Animals | Analysis of Variance | Dopamine Antagonists - pharmacology | Receptors, Dopamine D3 | Adrenergic Uptake Inhibitors - pharmacology | Mice | In Vitro Techniques | Neurons - radiation effects | Dose-Response Relationship, Radiation | Neural Inhibition - drug effects | Dopamine | Neurons | Experiments | Variance analysis | Rodents | Parkinsons disease
Journal Article
Nature, ISSN 0028-0836, 02/2007, Volume 445, Issue 7128, pp. 643 - 647
The striatum is a major forebrain nucleus that integrates cortical and thalamic afferents and forms the input nucleus of the basal ganglia(1,2). Striatal... 
DOPAMINE D2 RECEPTORS | BASAL GANGLIA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | NEURONS | HYDROLYSIS | MICE | INTERNEURONS | MODULATION | TERM SYNAPTIC DEPRESSION | PLASTICITY | Cannabinoid Receptor Modulators - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Benzoxazines | Long-Term Synaptic Depression - drug effects | Receptors, Dopamine D2 - metabolism | Excitatory Postsynaptic Potentials - drug effects | Psychomotor Performance - physiology | Neostriatum - physiology | Excitatory Postsynaptic Potentials - physiology | Dopamine - deficiency | Neuronal Plasticity - physiology | Oxidopamine - pharmacology | Synapses - metabolism | Neostriatum - drug effects | Piperidines - pharmacology | Reserpine - pharmacology | Benzamides - pharmacology | Parkinson Disease - metabolism | Dopamine - metabolism | Endocannabinoids | Carbamates - pharmacology | Disease Models, Animal | Pyrazoles - pharmacology | Long-Term Synaptic Depression - physiology | Synapses - drug effects | Neostriatum - cytology | Receptors, Dopamine D2 - agonists | Morpholines - pharmacology | Mice, Transgenic | Naphthalenes - pharmacology | Receptor, Cannabinoid, CB1 - metabolism | Animals | Mice | In Vitro Techniques | Dopamine D2 Receptor Antagonists | Brain | Neurosciences | Neurotransmitters | Genetic disorders | Biomedical research | Neurons | Motor ability | Mental depression | Drug therapy
Journal Article
Life Sciences, ISSN 0024-3205, 2006, Volume 79, Issue 4, pp. 331 - 341
CYP1A2, a principal catalyst for metabolism of various therapeutic drugs and carcinogens, among others, is in part regulated by the stress response. This study... 
Benzo( α)pyrene | Catecholamines | Adrenoceptors | Rat | CYP1A2 | Benzo(α)pyrene | benzo(alpha)pyrene | MEDICINE, RESEARCH & EXPERIMENTAL | catecholamines | rat | BIOACTIVATION | METABOLIC-ACTIVATION | CYTOCHROMES P-450 | ENZYMES | LIVER | PHARMACOLOGY & PHARMACY | HYDROCARBON RECEPTOR | adrenoceptors | RAT-BRAIN | STRESS | NORADRENALINE | Gene Expression Regulation, Enzymologic - drug effects | Up-Regulation | Catecholamines - metabolism | Rats, Wistar | Male | Adrenergic alpha-Antagonists - pharmacology | RNA, Messenger - metabolism | Prazosin - pharmacology | Cytochrome P-450 CYP1A2 - genetics | Sympatholytics - pharmacology | Reserpine - pharmacology | Dexmedetomidine - pharmacology | Benzo(a)pyrene - pharmacology | Oxidoreductases - biosynthesis | Levodopa - pharmacology | Signal Transduction | Oxidoreductases - genetics | Receptors, Adrenergic - metabolism | Rats | Animals | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Adrenergic Uptake Inhibitors - pharmacology | Adrenergic alpha-Agonists - pharmacology | Cytochromes | Guanethidine - pharmacology | Epinephrine - pharmacology | Comparative Study | Reserpine/pharmacology | Cytochrome P-450 Enzyme System/biosynthesis/genetics | Receptors; Adrenergic/metabolism | Dexmedetomidine/pharmacology | Oxidoreductases/biosynthesis/genetics | Research Support; Non-U.S. Gov't | Epinephrine/pharmacology | Guanethidine/pharmacology | Gene Expression Regulation; Enzymologic/drug effects | Cytochrome P-450 CYP1A2/genetics | Rats; Wistar | RNA; Messenger/metabolism | Adrenergic alpha-Agonists/pharmacology | Prazosin/pharmacology | Benzo(a)pyrene/pharmacology | Sympatholytics/pharmacology | Adrenergic Uptake Inhibitors/pharmacology | Catecholamines/metabolism | Adrenergic alpha-Antagonists/pharmacology | Levodopa/pharmacology
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2011, Volume 184, Issue 2, pp. 269 - 276
Journal Article
Journal Article
Synapse, ISSN 0887-4476, 05/2008, Volume 62, Issue 5, pp. 379 - 388
Cytochrome P450 2E1 (CYP2E1) has been detected in brain regions which are of relevance for the pathophysiology of Parkinson's disease, such as the substantia... 
substantia nigra | cytochrome P450 2E1 | phenylethyl isothiocyanate | microdialysis | Phenylethyl isothiocyanate | Microdialysis | Substantia nigra | Cytochrome P450 2E1 | PHENETHYL ISOTHIOCYANATE | OXIDATIVE STRESS | RAT-BRAIN SYNAPTOSOMES | HUMAN LIVER-MICROSOMES | NEUROSCIENCES | PERFORMANCE LIQUID-CHROMATOGRAPHY | STRIATAL DOPAMINE | ELECTROCHEMICAL DETECTION | DENDRO-DENDRITIC SYNAPSES | VOLATILE ANESTHETICS | DA | PARKINSONS-DISEASE | Synaptic Transmission - physiology | Anesthetics, Dissociative - pharmacology | Isoflurane - pharmacology | Extracellular Space - drug effects | Male | Cytochrome P-450 CYP2E1 - metabolism | Extracellular Space - metabolism | Parabens - metabolism | Dopamine - physiology | GABA Modulators - pharmacology | Xylazine - pharmacology | Free Radicals - metabolism | Reserpine - pharmacology | Tetrodotoxin - pharmacology | Dopamine - metabolism | Substantia Nigra - enzymology | Anesthetics, Inhalation - pharmacology | Cytochrome P-450 CYP2E1 Inhibitors | Dopamine Uptake Inhibitors - pharmacology | Hydroxybenzoates - metabolism | 4-Butyrolactone - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Piperazines - pharmacology | Rats, Sprague-Dawley | Animals | Dopamine Antagonists - pharmacology | Adrenergic alpha-Agonists - pharmacology | In Vitro Techniques | Ketamine - pharmacology | Index Medicus | Tetrodotoxin | Enzyme Inhibitors | GABA Modulators | Dissociative | Extracellular Space | Synaptic Transmission | Sprague-Dawley | Cytochrome P-450 CYP2E1 | pharmacology | 4-Butyrolactone | Physiology | Dopamine Antagonists | Reserpine | Dopamine Uptake Inhibitors | Adrenergic alpha-Agonists | Dopamine | Piperazines | Free Radicals | Substantia Nigra | Fysiologi | Xylazine | drug effects | Anesthetics | antagonists & inhibitors | Isoflurane | enzymology | Inhalation | Parabens | Hydroxybenzoic Acids | Ketamine | metabolism
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2008, Volume 28, Issue 35, pp. 8682 - 8690
The striatum plays a central role in sensorimotor learning and action selection. Tonically active cholinergic interneurons in the striatum give rise to dense... 
Cholinergic neuron | Striatum | ACh | Patch clamp | Acetylcholine | Microcircuit | Nicotinic receptor | RAT NEOSTRIATUM | cholinergic neuron | patch clamp | DOPAMINE RELEASE | TONICALLY ACTIVE NEURONS | MECHANISMS | NICOTINIC ACETYLCHOLINE-RECEPTORS | SYNAPTIC PLASTICITY | NEUROSCIENCES | MEDIATED MODULATION | striatum | GIANT ASPINY INTERNEURONS | nicotinic receptor | CHANNELS | microcircuit | acetylcholine | PRIMATES STRIATUM | Interneurons - physiology | Cholinergic Fibers - physiology | Acetylcholine - metabolism | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Corpus Striatum - cytology | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Neural Inhibition - physiology | Neural Inhibition - radiation effects | Drug Interactions | Excitatory Amino Acid Agents - pharmacology | Reserpine - pharmacology | alpha-Methyltyrosine - pharmacology | Cholinergic Fibers - drug effects | Nicotinic Agonists - pharmacology | Animals, Newborn | Enzyme Inhibitors - pharmacology | Inhibitory Postsynaptic Potentials - physiology | Rats | Rats, Sprague-Dawley | Inhibitory Postsynaptic Potentials - radiation effects | GABA Antagonists - pharmacology | Animals | Adrenergic Uptake Inhibitors - pharmacology | In Vitro Techniques | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2005, Volume 25, Issue 8, pp. 2157 - 2165
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of G GTPase accelerating proteins, is expressed specifically in the striatum, which... 
DEP domain | Striatum | Antipsychotic | RGS9 | dopamine receptor | Dyskinesia | Antipsychotic Agents - toxicity | RGS Proteins - genetics | Reserpine - toxicity | Sulpiride - pharmacology | Antiparkinson Agents - pharmacology | Dyskinesia, Drug-Induced - physiopathology | Humans | Recombinant Fusion Proteins - physiology | Antiparkinson Agents - toxicity | RGS Proteins - physiology | Dopamine Agents - therapeutic use | Receptors, Dopamine D2 - metabolism | Antiparkinson Agents - therapeutic use | Transfection | Apomorphine - pharmacology | Dopamine - physiology | Dopamine Agents - pharmacology | RGS Proteins - deficiency | Dopamine Antagonists - toxicity | Reserpine - pharmacology | Female | Haloperidol - pharmacology | Receptors, G-Protein-Coupled - physiology | Protein Structure, Tertiary | Corpus Striatum - physiopathology | Parkinson Disease - physiopathology | Receptors, Dopamine D2 - genetics | Mice, Knockout | Protein Interaction Mapping | Patch-Clamp Techniques | Animals | Movement Disorders - physiopathology | Dopamine Antagonists - pharmacology | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Corpus Striatum - drug effects | Mice | Quinpirole - pharmacology | Antipsychotic Agents - pharmacology | Movement Disorders - genetics | Haloperidol - toxicity | Subcellular Fractions - chemistry | Receptors, Dopamine D1 - genetics | striatum | Neurobiology of Disease | antipsychotic | dyskinesia | D2 dopamine receptor
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2012, Volume 56, Issue 1, pp. 324 - 331
Journal Article