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Cell, ISSN 0092-8674, 09/2017, Volume 170, Issue 6, pp. 1247 - 1257.e12
The respiratory megacomplex represents the highest-order assembly of respiratory chain complexes, and it allows mitochondria to respond to energy-requiring... 
electron transfer pathway | megacomplex | cryo-EM | mitochondria | oxidative phosphorylation | human respiratory chain | CHAIN | CYTOCHROME-C-OXIDASE | COMPLEX-III | PROTEIN | SUPERCOMPLEX | RESPIRASOME | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BEAM-INDUCED MOTION | STABILIZES | ELECTRON-TRANSPORT | CELL BIOLOGY
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 04/2014, Volume 1837, Issue 4, pp. 444 - 450
Mitochondria are important organelles not only as efficient ATP generators but also in controlling and regulating many cellular processes. Mitochondria are... 
OXPHOS | Respirasome | Metabolism | Mitochondrial supercomplex | OXIDATIVE-PHOSPHORYLATION | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART | CYTOCHROME-C-OXIDASE | CHAIN SUPERCOMPLEXES | BIOPHYSICS | ATP SYNTHASE | COMPLEX-I | CARDIAC-HYPERTROPHY | PROTEIN COMPLEXES | MITOCHONDRIAL SUPERCOMPLEXES | Mitochondrial DNA
Journal Article
Nature, ISSN 0028-0836, 11/2016, Volume 539, Issue 7630, pp. 579 - 582
Respiratory chain complexes can super-assemble into quaternary structures called supercomplexes that optimize cellular metabolism(1). The interaction between... 
CHAIN | ORGANIZATION | CYTOCHROME-C-OXIDASE | COX7A2L | SUPERCOMPLEX | RESPIRASOME | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | Animals | Protein Isoforms - metabolism | Electron Transport Complex IV - chemistry | Mitochondrial Membranes - metabolism | Physiological aspects | Mitochondria | Cell research | Genetic aspects | Heart | Respiration | Molecular biology | Index Medicus
Journal Article
Science, ISSN 0036-8075, 6/2013, Volume 340, Issue 6140, pp. 1567 - 1570
Journal Article
ANTIOXIDANTS & REDOX SIGNALING, ISSN 1523-0864, 01/2017, Volume 26, Issue 2, pp. 84 - 103
Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we... 
CELLS | METFORMIN | APOPTOSIS | SUPEROXIDE-PRODUCTION | PHOSPHORYLATION | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC-CANCER | breast cancer | respirasome | COMPLEX-I ACTIVITY | ELECTRON-TRANSPORT CHAIN | ALPHA-TOCOPHERYL SUCCINATE | MITOCHONDRIAL RESPIRATION | mitochondrially targeted tamoxifen | ENDOCRINOLOGY & METABOLISM | HER2
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 10/2014, Volume 1837, Issue 10, pp. 1717 - 1729
In plants, channeling of cytochrome molecules between complexes III and IV has been purported to shuttle electrons within the supercomplexes instead of... 
Arabidopsis thaliana | Cytochrome c | Supercomplex | NMR | Respirasome | Cytochrome bc1 complex
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2012, Volume 53, Issue 6, pp. 1252 - 1263
Cytochrome oxidase (CcO) is the terminal oxidase of the mitochondrial electron transport chain. This bigenomic enzyme in mammals contains 13 subunits of which... 
Cytochrome c oxidase | Protein kinse A | Oxidative stress | Phosphorylation | Mitochondrial dysfunction | Drug effects | Myocardial ischemia | mtDNA mutations | Regulation of enzyme activity | Alcohol toxicity | cAMP | Respirasome assembly | LON PROTEASE | CHRONIC ALCOHOL-CONSUMPTION | RESPIRATORY-CHAIN | TYROSINE PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL ELECTRON-TRANSPORT | ALLOSTERIC ATP-INHIBITION | SUBUNIT-I | MYOCARDIAL-ISCHEMIA | COMPLEX-I | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | Mitochondria - enzymology | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Enzyme Stability | Mitochondria - metabolism | Electron Transport Complex IV - genetics | Protein Subunits - metabolism | Electron Transport Complex IV - metabolism | Animals | Protein Isoforms - metabolism | Membrane Potential, Mitochondrial | Electron Transport Complex IV - physiology | Mitochondria - physiology | Apoptosis | Protein Isoforms - genetics | Protein Subunits - genetics | Cytochrome c | Nervous system diseases | RNA | Genes | Heme | Physiological aspects | Cytochrome oxidase | Mitochondrial DNA | Adenylic acid | Cells | Index Medicus | respirasome assembly | regulation of enzyme activity | alcohol toxicity | drug effects | Cytochrome C Oxidase | mitochondrial dysfunction | myocardial ischemia | phosphorylation | oxidative stress
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2017, Volume 25, Issue 1, pp. 4 - 5
Understanding the mammalian respiratory complex I assembly has been an arduous task due to the lack of appropriate techniques and the complexity of the... 
assembly | supercomplexes | complex I | OXPHOS | respiratory complexes | mitochondria | SUBUNITS | MITOCHONDRIAL | RESPIRASOME | ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Mitochondria | Animals | Electron Transport Complex I | Humans | Oxidative Phosphorylation
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 06/2010, Volume 1797, Issue 6-7, pp. 664 - 670
The five complexes (complexes I–V) of the oxidative phosphorylation (OXPHOS) system of mitochondria can be extracted in the form of active supercomplexes.... 
Supercomplex | Mitochondria | ATP synthase | Oxidative phosphorylation | Respirasome | Electron microscopy | RESPIRATORY COMPLEX-I | CARDIOLIPIN | DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIMERIC ATP SYNTHASE | IDENTIFICATION | 3-DIMENSIONAL STRUCTURE | ORGANIZATION | YEAST | CYTOCHROME-C-OXIDASE | CHAIN SUPERCOMPLEXES | BIOPHYSICS | Oligomers | Mitochondrial DNA | Plant genetics
Journal Article