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Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e100392
The development of safe and effective vaccines against both bovine and human respiratory syncytial viruses (BRSV, HRSV) to be used in the presence of... 
GNOTOBIOTIC CALVES | SEQUENCE-ANALYSIS | PROTECTIVE IMMUNITY | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | DISEASE | COTTON RATS | FUSION GLYCOPROTEIN | MONOCLONAL-ANTIBODIES | VIRAL-INFECTION | CROSS-PRESENTATION | Respiratory Syncytial Virus, Human - metabolism | Respiratory Syncytial Virus Vaccines - immunology | Lymph Nodes - pathology | Species Specificity | Humans | Vaccination | Virulence | Molecular Sequence Data | Antibodies, Viral - blood | Respiratory Syncytial Virus Infections - immunology | Viral Proteins - metabolism | Viral Load | Epitopes - immunology | Respiratory Syncytial Virus Vaccines - adverse effects | Lung - virology | Lymphocytes - immunology | Cattle | Gene Deletion | Respiratory Syncytial Virus Infections - blood | Genes, Viral | Vaccines, Subunit - adverse effects | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus Infections - virology | Respiratory Syncytial Virus, Bovine - genetics | Amino Acid Sequence | Lung - pathology | Vaccines, Subunit - immunology | Animals | Respiratory Syncytial Virus, Human - immunology | Antibodies, Viral - immunology | Epitopes - chemistry | Lung - immunology | Respiratory Syncytial Virus, Bovine - pathogenicity | Disease | Mucosa | Genes | Antibodies | Viruses | Lymphocytes T | Infections | Vaccines | Gene deletion | Immunoglobulin A | Veterinary medicine | Proteins | Immunology | Clonal deletion | Deletion | Safety | Recombinant | Formulations | Pathogens | Antigens | Immunization | Parasitology | Immunoglobulins | Dendritic cells | Mortality | Immune response (cell-mediated) | Calves | Priming | Glycoproteins | Epitopes | Disease control | Virology | Respiratory syncytial virus | Respiratory diseases | Neutralizing | Genetic engineering | Mutation
Journal Article
Veterinary Immunology and Immunopathology, ISSN 0165-2427, 10/2016, Volume 178, pp. 88 - 98
Journal Article
Journal of General Virology, ISSN 0022-1317, 07/2017, Volume 98, Issue 7, pp. 1587 - 1599
Journal Article
Journal of General Virology, ISSN 0022-1317, 2014, Volume 95, Issue 6, pp. 1244 - 1254
Bovine respiratory syncytial virus (BRSV) causes inflammation and obstruction of the small airways, leading to severe respiratory disease in young calves. The... 
RESPONSES | INTERLEUKIN-1 | VIROLOGY | MEMBRANE-PERMEABILITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | VACCINE | DISEASE | CELL-CULTURE | INFECTION | INFLUENZA-VIRUS | MONOCLONAL-ANTIBODIES | SMALL HYDROPHOBIC PROTEIN | Respiratory Syncytial Virus Vaccines - immunology | Humans | Immunity, Mucosal | Retroviridae Proteins, Oncogenic - immunology | Vaccines, Synthetic - immunology | Respiratory Syncytial Virus Infections - immunology | Respiratory System - virology | Virulence - genetics | Cattle | Cattle Diseases - virology | Gene Deletion | Genes, Viral | Inflammation Mediators - metabolism | Respiratory Syncytial Virus Infections - prevention & control | Interleukin-1beta - biosynthesis | Respiratory Syncytial Virus Infections - veterinary | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus, Human - pathogenicity | Cattle Diseases - prevention & control | Respiratory Syncytial Virus, Bovine - genetics | Vaccines, Synthetic - genetics | Cattle Diseases - immunology | Vaccines, Attenuated - immunology | Animals | Respiratory Syncytial Virus, Human - immunology | Virulence - immunology | Retroviridae Proteins, Oncogenic - genetics | Respiratory Syncytial Virus Vaccines - genetics | Tumor Necrosis Factor-alpha - biosynthesis | Cytokines - biosynthesis | Apoptosis | Respiratory Syncytial Virus, Bovine - pathogenicity | Vaccines, Attenuated - genetics | Animal | Standard
Journal Article
Veterinary Research, ISSN 0928-4249, 03/2007, Volume 38, Issue 2, pp. 153 - 180
Journal Article
Comparative Immunology, Microbiology and Infectious Diseases, ISSN 0147-9571, 2012, Volume 35, Issue 3, pp. 253 - 257
Abstract Bovine respiratory syncytial virus (BRSV) is a respiratory pathogen of cattle that causes severe disease in calves alone and as one of several viruses... 
Infectious Disease | Allergy and Immunology | Vaccine | Immunomodulation | Immunity | IgE | Bovine respiratory syncytial virus | LYMPH | MICROBIOLOGY | PULMONARY-FUNCTION | IMMUNOLOGY | BRSV | CHALLENGE | T-CELL RESPONSES | DISEASE | VETERINARY SCIENCES | CALVES | EXPRESSION | Cattle - virology | Respiratory Syncytial Virus Vaccines - immunology | Dendritic Cells - immunology | Cattle Diseases - pathology | Vaccination - veterinary | Th1 Cells - immunology | Respiratory Syncytial Virus Infections - immunology | Cattle Diseases - immunology | Cattle - immunology | Animals | Immunoglobulin E - immunology | Cattle Diseases - virology | Interferon-gamma - immunology | Respiratory Syncytial Virus Vaccines - administration & dosage | Respiratory Syncytial Virus Infections - veterinary | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus Infections - pathology | Respiratory Syncytial Virus Infections - virology | Immunity, Cellular | Respiratory Syncytial Virus, Bovine - pathogenicity | Virus diseases | Immunoglobulins | Cattle | Analysis | Vaccination | Immunoglobulin E | Beef cattle | Biological response modifiers | Health aspects | Pathogens | Immune response | Dendritic cells | CD8 antigen | Lung | Helper cells | Adjuvants | Cytotoxicity | Lymphocytes T | Experimental infection | Reviews | Immunopathogenesis | gamma -Interferon
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 47, pp. 8719 - 8730
Highlights ► BRSV-ISCOMs induce strong clinical and virological protection in young conventional calves with BRSV-specific maternal antibodies. ► Protection is... 
Allergy and Immunology | Vaccine | Respiratory syncytial virus | ISCOM | Bovine respiratory disease | Bronchiolitis | MEDICINE, RESEARCH & EXPERIMENTAL | EFFICACY | CALF | IMMUNOLOGY | BRSV | INACTIVATED VACCINE | RESPONSES | RT-PCR | DISEASE | MATERNAL ANTIBODIES | EXPERIMENTAL-INFECTION | SERONEGATIVE CALVES | Respiratory System - pathology | Bronchiolitis - veterinary | Immunoglobulin G - blood | Drug Carriers - administration & dosage | Viral Vaccines - adverse effects | Antibodies, Viral - blood | Bronchiolitis - prevention & control | Respiratory System - virology | Vaccination - methods | Cattle | Injections, Subcutaneous | Leukocytes, Mononuclear - immunology | Respiratory Syncytial Virus Infections - prevention & control | Respiratory Syncytial Virus Infections - veterinary | Respiratory Syncytial Virus, Bovine - immunology | Respiratory System - immunology | Cattle Diseases - prevention & control | Severity of Illness Index | ISCOMs - administration & dosage | Bronchiolitis - pathology | Europe | Pneumonia, Viral - pathology | Immunization, Secondary - methods | Cattle Diseases - pathology | Viral Vaccines - administration & dosage | Animals | Pneumonia, Viral - prevention & control | Pneumonia, Viral - veterinary | Respiratory Syncytial Virus Infections - pathology | Viral Vaccines - immunology | Immunoglobulin A - analysis | Virus diseases | Safety and security measures | Immunoglobulin A | T cells | Animal vaccines | Infections | Antigen presentation | Cell culture | Excretion | Pneumonia | Immune response | Bronchopneumonia | Lung | Helper cells | Adjuvants | Lymphocytes T | Vaccines | Morbidity | Infection | Polymerase chain reaction | Respiratory tract | Temperature effects | Aerosols | Replication | Age | ISCOMS | Veterinary Science | Veterinärmedicin | Animal and Dairy Science | Husdjursvetenskap
Journal Article
Immunology, ISSN 0019-2805, 06/2013, Volume 139, Issue 2, pp. 227 - 244
Summary γδ T cells respond to stimulation via toll‐like receptors (TLR). Bovine γδ T cells express TLR3 and TLR7, receptors that are key for the recognition of... 
toll‐like receptors | respiratory syncytial virus | vitamin D | bovine γδ T cells | Toll-like receptors | Bovine γδ T cells | Respiratory syncytial virus | Vitamin D | T-Lymphocyte Subsets - immunology | Aminoquinolines - immunology | Membrane Glycoproteins - metabolism | Gene Expression Profiling | Respiratory Syncytial Virus Infections - immunology | Host-Pathogen Interactions - immunology | Flow Cytometry | Time Factors | Cattle | T-Lymphocyte Subsets - drug effects | Toll-Like Receptor 7 - immunology | Poly I-C - immunology | Respiratory Syncytial Virus, Bovine - immunology | Membrane Glycoproteins - immunology | Toll-Like Receptors - metabolism | Respiratory Syncytial Virus Infections - virology | Aminoquinolines - pharmacology | Cytokines - genetics | Chemokines - immunology | Cytokines - immunology | Animals, Newborn | Toll-Like Receptor 7 - agonists | Poly I-C - pharmacology | Toll-Like Receptor 7 - metabolism | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Toll-Like Receptors - immunology | Cells, Cultured | Receptors, Antigen, T-Cell, gamma-delta - immunology | Toll-Like Receptor 3 - immunology | Toll-Like Receptor 3 - agonists | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 3 - metabolism | Chemokines - genetics | T-Lymphocyte Subsets - virology | Toll-Like Receptors - agonists | Animals | Respiratory Syncytial Virus, Bovine - physiology | Chemokines - metabolism | toll-like receptors | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0151083
Human respiratory syncytial virus (HRSV) is a leading cause of severe lower respiratory tract infection in children under five years of age. IL-17 and Th17... 
WILD-TYPE | CYTOKINE PRODUCTION | MULTIDISCIPLINARY SCIENCES | DISEASE | INFANTS | ANIMAL-MODELS | CALVES | MYCOBACTERIUM-BOVIS | EXPRESSION | RESPIRATORY SYNCYTIAL VIRUS | VIRAL-INFECTION | Pasteurellaceae Infections - microbiology | Vaccination | Respiratory Syncytial Virus Infections - immunology | CD4-Positive T-Lymphocytes - immunology | Lung - virology | Cattle | Respiratory Syncytial Virus Infections - blood | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus Infections - virology | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Lung - pathology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Coinfection - immunology | Cells, Cultured | Mannheimia haemolytica - immunology | Pasteurellaceae Infections - immunology | Interleukin-17 - biosynthesis | Coinfection - virology | Coinfection - microbiology | Pasteurellaceae Infections - blood | Vaccines, Attenuated - immunology | Animals | Th17 Cells - immunology | Lung - immunology | Respiratory syncytial virus | Immune response | Interleukins | Physiological aspects | Genetic aspects | Research | T cells | Veterinary colleges | Pathogenesis | Helper cells | Animal diseases | Interleukin 22 | Viruses | Lymphocytes T | Infections | Cattle industry | Veterinary medicine | Streptococcus infections | Respiratory tract | Immunology | Lymphocytes | Interleukin 21 | Peripheral blood mononuclear cells | Respiratory tract diseases | Bacteria | Children | Antigens | Cytokines | Mortality | Calves | T cell receptors | Morbidity | Interleukin 17 | CD4 antigen | Lungs | Respiratory diseases | Viral infections
Journal Article