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1. Full Text Vagal afferent innervation of the airways in health and disease
by Mazzone, Stuart B and Undem, Bradley J
Physiological Reviews, ISSN 0031-9333, 07/2016, Volume 96, Issue 3, pp. 975 - 1024
Vagal sensory neurons constitute the major afferent supply to the airways and lungs. Subsets of afferents are defined by their embryological origin, molecular... 
RAPIDLY ADAPTING RECEPTORS | BRONCHOPULMONARY C-FIBERS | RAT SPINAL-CORD | PHYSIOLOGY | NUCLEUS-TRACTUS-SOLITARIUS | GENE-RELATED PEPTIDE | ANESTHETIZED GUINEA-PIGS | PULMONARY STRETCH RECEPTORS | URGE-TO-COUGH | LUNG IRRITANT RECEPTORS | DORSAL-ROOT REFLEXES | Vagus Nerve - physiology | Animals | Sensory Receptor Cells - physiology | Respiratory System - innervation | Humans | Respiration Disorders - physiopathology | Respiratory System - physiopathology | Vagus nerve stimulation | Care and treatment | Research | Receptor-mediated endocytosis | Lung diseases | Neurobiology | Reviews
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2. Full Text A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle
by Radzikinas, Kelsi and Aven, Linh and Jiang, Zhihua and Tran, Thanh and Paez-Cortez, Jesus and Boppidi, Karthik and Lu, Jining and Fine, Alan and Ai, Xingbin
Journal of Neuroscience, ISSN 0270-6474, 10/2011, Volume 31, Issue 43, pp. 15407 - 15415
Dysfunctional neural control of airway smooth muscle (ASM) is involved in inflammatory diseases, such as asthma. However, neurogenesis in the lung is poorly... 
MORPHOGENESIS | GANGLIA | SONIC HEDGEHOG | NEUROTROPHIC FACTOR | ALLERGIC-ASTHMA | TISSUE | MICRORNAS | EXPRESSION | NEUROSCIENCES | MOUSE LUNG | NERVE GROWTH-FACTOR | Brain-Derived Neurotrophic Factor - genetics | Muscle, Smooth - innervation | Age Factors | Embryo, Mammalian | Gene Expression Regulation, Developmental - genetics | Hedgehog Proteins - metabolism | Mice, Transgenic | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | Signal Transduction - genetics | RNA, Messenger - metabolism | Respiratory System - anatomy & histology | Tubulin - metabolism | Animals | Hedgehog Proteins - genetics | Respiratory System - innervation | Muscle, Smooth - physiology | Brain-Derived Neurotrophic Factor - metabolism | Mice | MicroRNAs - genetics | Respiratory System - embryology
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3. Full Text Electrophysiological properties of rostral ventrolateral medulla presympathetic neurons modulated by the respiratory network in rats
by Moraes, Davi J. A and da Silva, Melina P and Bonagamba, Leni G. H and Mecawi, André S and Zoccal, Daniel B and Antunes-Rodrigues, José and Varanda, Wamberto A and Machado, Benedito H
Journal of Neuroscience, ISSN 0270-6474, 2013, Volume 33, Issue 49, pp. 19223 - 19237
The respiratory pattern generator modulates the sympathetic outflow, the strength of which is enhanced by challenges produced by hypoxia. This coupling is due... 
Intrinsic electrophysiological properties | Bulbospinal RVLM presympathetic neurons | Respiratory-sympathetic coupling | Chronic intermittent hypoxia | POTASSIUM CURRENTS | BAROSENSITIVE NEURONS | VASOMOTOR NEURONS | bulbospinal RVLM presympathetic neurons | MAGNOCELLULAR NEURONS | MORPHOLOGICAL PROPERTIES | NEUROSCIENCES | HYPOTHALAMIC PARAVENTRICULAR NUCLEUS | BULBOSPINAL NEURONS | IN-VITRO | respiratory-sympathetic coupling | intrinsic electrophysiological properties | SYMPATHETIC-NERVE ACTIVITY | chronic intermittent hypoxia | Voltage-Dependent Anion Channels - physiology | Calcium Channels, T-Type - physiology | Rats, Wistar | Respiratory Muscles - physiology | Respiratory Muscles - innervation | Heart - physiology | Sympathetic Nervous System - cytology | Electrophysiological Phenomena - physiology | Rats | Male | Sodium Channels - physiology | Hemodynamics - physiology | Brain Stem - physiology | Respiratory Physiological Phenomena | Medulla Oblongata - cytology | Patch-Clamp Techniques | Animals | Sympathetic Nervous System - physiology | Respiratory System - innervation | Neurons - physiology | Hypoxia - physiopathology | Electromyography | Medulla Oblongata - physiology | Heart - innervation
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4. Full Text Cystic Fibrosis and the Nervous System
by Reznikov, Leah R., PhD
Chest, ISSN 0012-3692, 2016, Volume 151, Issue 5, pp. 1147 - 1155
Cystic fibrosis (CF) is a life-shortening autosomal recessive disorder caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance... 
Pulmonary/Respiratory | mucus secretion | nervous system | cough | glucose regulation | cystic fibrosis | CFTR | CFTR-DEFICIENT PIGS | DEVELOPMENTAL REGULATION | KNOCKOUT MICE | TRANSMEMBRANE CONDUCTANCE REGULATOR | PULMONARY NEUROENDOCRINE CELLS | SMOOTH-MUSCLE | RESPIRATORY SYSTEM | TRACHEAL SUBMUCOSAL GLANDS | PROTEIN EXPRESSION | LUNG-DISEASE | ATP RELEASE | CRITICAL CARE MEDICINE | Intestinal Obstruction - physiopathology | Exocrine Pancreatic Insufficiency - metabolism | Central Nervous System - metabolism | Cystic Fibrosis - physiopathology | Humans | Malabsorption Syndromes - metabolism | Autonomic Nervous System - physiopathology | Gastrointestinal Motility | Exocrine Pancreatic Insufficiency - physiopathology | Pancreas - innervation | Malabsorption Syndromes - physiopathology | Autonomic Nervous System - metabolism | Gastrointestinal Tract - innervation | Disease Models, Animal | Heart - innervation | Intestinal Obstruction - etiology | Muscle, Smooth - innervation | Sweating | Peripheral Nervous System - physiopathology | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Cystic Fibrosis - complications | Cough | Animals | Malabsorption Syndromes - etiology | Muscle Contraction | Exocrine Pancreatic Insufficiency - etiology | Respiratory System - innervation | Cystic Fibrosis - genetics | Peripheral Nervous System - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Central Nervous System - physiopathology | Intestinal Obstruction - metabolism | cAMP, cyclic adenosine monophosphate | CF, cystic fibrosis | CFRD, cystic-fibrosis-related diabetes | ATP, adenosine triphosphate | CFTR, cystic fibrosis transmembrane conductance regulator
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5. Full Text Understanding the rhythm of breathing: So near, yet so far
by Feldman, Jack L and Del Negro, Christopher A and Gray, Paul A
Annual Review of Physiology, ISSN 0066-4278, 02/2013, Volume 75, Issue 1, pp. 423 - 452
Breathing is an essential behavior that presents a unique opportunity to understand how the nervous system functions normally, how it balances inherent... 
Central pattern generation | Parafacial respiratory group | Brain stem | PreBötzinger Complex | Retrotrapezoid nucleus | CENTRAL HYPOVENTILATION SYNDROME | RECEPTOR-IMMUNOREACTIVE NEURONS | PHYSIOLOGY | CENTRAL PATTERN GENERATOR | VENTRAL RESPIRATORY GROUP | INFANT-DEATH-SYNDROME | parafacial respiratory group | PERSISTENT SODIUM CURRENT | retrotrapezoid nucleus | NONSPECIFIC CATION CURRENT | RAPID-ONSET OBESITY | central pattern generation | brain stem | PRE-BOTZINGER COMPLEX | preBotzinger Complex | DEPENDENT POTASSIUM CHANNELS | Respiratory Physiological Phenomena | Inhalation - physiology | Animals | Exhalation - physiology | Respiratory System - innervation | Humans | Periodicity | Respiration | Medulla Oblongata - physiology | Respiratory Mechanics - physiology | Physiological aspects | Neural circuitry | Health aspects | Central nervous system
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6. Full Text Central mechanisms regulating coordinated cardiovascular and respiratory function during stress and arousal
by Dampney, Roger A. L
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 09/2015, Volume 309, Issue 5, pp. R429 - R443
Actual or potentially threatening stimuli in the external environment (i.e., psychological stressors) trigger highly coordinated defensive behavioral responses... 
Midbrain | Sympathetic activity | Sympathetic premotor nuclei | Hypothalamus | Respiratory activity | Defensive behavior | PHYSIOLOGY | mid-brain | respiratory activity | defensive behavior | sympathetic activity | PARAVENTRICULAR HYPOTHALAMIC NUCLEUS | MENTAL STRESS | OREXIN KNOCKOUT MICE | DORSOLATERAL PERIAQUEDUCTAL GRAY | ROSTRAL VENTROLATERAL MEDULLA | sympathetic premotor nuclei | SYMPATHETIC-NERVE ACTIVITY | MEDIAL PREFRONTAL CORTEX | DORSOMEDIAL HYPOTHALAMUS | ADIPOSE-TISSUE THERMOGENESIS | hypothalamus | C-FOS EXPRESSION | Adaptation, Physiological | Lung - innervation | Brain - physiopathology | Humans | Stress, Physiological | Cardiovascular System - innervation | Sympathetic Nervous System - physiopathology | Animals | Arousal | Hemodynamics | Neural Pathways - physiopathology | Respiration | Adaptation, Psychological | Stress, Psychological - physiopathology | Physiological aspects | Evaluation | Brain | Nervous system, Sympathetic | Stress (Psychology) | Arousal (Physiology)
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7. Full Text Mechanisms of respiratory innervation during embryonic development
by Aven, Linh and Ai, Xingbin
Organogenesis, ISSN 1547-6278, 07/2013, Volume 9, Issue 3, pp. 194 - 198
During embryogenesis, the development of the respiratory tract is closely associated with the formation of an extensive neuronal network. While the topic of... 
intrinsic neuron | respiratory tract | glial cell-derived neurotrophic factor | extrinsic neuron | brain-derived neurotrophic factor | neurotrophin | lung development | Neurotrophin | Respiratory tract | Brain-derived neurotrophic factor | Glial cell-derived neurotrophic factor | Extrinsic neuron | Lung development | Intrinsic neuron | NEUROEPITHELIAL BODIES | ENTERIC NERVOUS-SYSTEM | ENGINEERING, BIOMEDICAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRINSIC INNERVATION | DEVELOPMENTAL BIOLOGY | NEURAL CREST CELLS | AFFERENT-PROJECTIONS | MICE LACKING GDNF | FETAL LUNG | NEURONS | AIRWAY SMOOTH-MUSCLE | Animals | Signal Transduction | Nerve Growth Factors | Neurons | Respiratory System - innervation | Humans | Brain-Derived Neurotrophic Factor | Rats | Mice | Embryonic Development | Respiratory System - anatomy & histology | Respiratory System - embryology | Special Focus Review
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8. Autonomic control of the respiratory system
by Barnes, Peter J., 1946
1997, Autonomic nervous system, ISBN 9783718651405, Volume 7, xvi, 349
Regulation | Biological control systems | Respiration | Autonomic nervous system
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9. Full Text Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways
by Dimitri Tränkner and Nadeau Hahne and Ken Sugino and Mark A. Hoon and Charles Zuker
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 31, pp. 11515 - 11520
Asthma is a common debilitating inflammatory lung disease affecting over 200 million people worldwide. Here, we investigated neurogenic components involved in... 
Receptors | Lungs | Neurons | Body weight | Sensory neurons | Mice | Ova | Ganglia | Allergies | Asthma | Airway inflammation | Bronchospasms | airway inflammation | LUNG | TRPA1 | bronchospasms | MULTIDISCIPLINARY SCIENCES | TRACHEA | RECEPTOR | FIBERS | INFLAMMATION | REFLEX | ABLATION | EXPRESSION | VAGAL | Respiratory System - pathology | Pneumonia - physiopathology | Sensory Receptor Cells - pathology | Vagus Nerve - metabolism | Asthma - physiopathology | Mice, Inbred C57BL | Gene Silencing | Pneumonia - pathology | Bronchial Hyperreactivity - complications | Vagus Nerve - pathology | TRPV Cation Channels - metabolism | Bronchial Hyperreactivity - pathology | Animals | Asthma - complications | Respiratory System - innervation | Bronchial Hyperreactivity - physiopathology | Gene Deletion | Pneumonia - complications | Respiratory System - physiopathology | Sensory Receptor Cells - metabolism | Receptors, Lysosphingolipid - metabolism | Asthma - pathology | Development and progression | Physiological research | Immune response | Research | Biological Sciences
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10. Full Text Central pathways of pulmonary and lower airway vagal afferents
by Leszek Kubin and George F. Alheid and Edward J. Zuperku and Donald R. McCrimmon
Journal of Applied Physiology, ISSN 8750-7587, 08/2006, Volume 101, Issue 2, pp. 618 - 627
Lung sensory receptors with afferent fibers coursing in the vagus nerves are broadly divided into three groups: slowly (SAR) and rapidly (RAR) adapting stretch... 
Rapidly adapting receptor | Lung reflexes | C-fiber afferents | Respiratory control | Central pathways | Slowly adapting pulmonary stretch receptor | respiratory control | RAPIDLY ADAPTING RECEPTORS | central pathways | SPORT SCIENCES | PHYSIOLOGY | MEDULLARY RESPIRATORY NEURONS | INSPIRATORY-MODULATED NEURONS | LARYNGEAL NERVE-STIMULATION | NUCLEUS-TRACTUS-SOLITARII | RECEPTOR RELAY NEURONS | HERING-BREUER REFLEX | EXPIRATORY BULBOSPINAL NEURONS | lung reflexes | AXONAL HORSERADISH-PEROXIDASE | rapidly adapting receptor | slowly adapting pulmonary stretch receptor | BRAIN-STEM PROJECTIONS | Lung - innervation | Motor Neurons - physiology | Nerve Fibers, Unmyelinated - physiology | Reflex - physiology | Humans | Lung - physiology | Respiratory Physiological Phenomena | Solitary Nucleus - physiology | Vagus Nerve - physiology | Animals | Respiratory System - innervation | Afferent Pathways - physiology | Spinal Cord - physiology | Pulmonary Stretch Receptors - physiology | Sleep - physiology | Respiration | Medulla Oblongata - physiology | Respiratory Mechanics - physiology
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11. Full Text Neurogenic hypertension and the secrets of respiration
by Machado, Benedito H and Zoccal, Daniel B and Moraes, Davi J. A
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 06/2017, Volume 312, Issue 6, pp. R864 - R872
Despite recent advances in the knowledge of the neural control of cardiovascular function, the cause of sympathetic overactivity in neurogenic hypertension... 
Autonomic and respiratory networks | Presympathetic neurons | Neurogenic hypertension | Respiratory neurons | Sympathetic overactivity | OBSTRUCTIVE SLEEP-APNEA | PHYSIOLOGY | EXPIRATORY ACTIVITY | neurogenic hypertension | presympathetic neurons | JUVENILE RATS | NUCLEUS-TRACTUS-SOLITARII | PERIPHERAL CHEMOREFLEX | CHRONIC INTERMITTENT HYPOXIA | ACTIVE EXPIRATION | autonomic and respiratory networks | sympathetic overactivity | ROSTRAL VENTROLATERAL MEDULLA | respiratory neurons | HEART-RATE | Respiratory Center - physiopathology | Lung - innervation | Models, Cardiovascular | Humans | Cardiovascular System - innervation | Hypoxia - complications | Sympathetic Nervous System - physiopathology | Hypertension - physiopathology | Hypertension - etiology | Animals | Arterial Pressure | Hypoxia - physiopathology | Neural Pathways - physiopathology | Respiration | Disease Models, Animal | Hypertension | Physiological aspects | Review
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12. Relationship between sympathetic activity and pain intensity in fibromyalgia
by Zamunér, Antonio R.oberto and Zamunér, Antonio Roberto and Barbic, Franca and Barbic, Franca and Dipaola, Franca and Dipaola, Franca and Bulgheroni, Mara and Bulgheroni, Mara and Diana, Alessandro and Diana, Alessandro and Atzeni, Fabiola and Atzeni, Fabiola and Marchi, Andrea and Marchi, Andrea and Sarzi-Puttini, Piercarlo and Sarzi-Puttini, Piercarlo and Porta, Alberto and Porta, Alberto and Furlan, Raffaello and Furlan, Raffaello
Clinical and experimental rheumatology, ISSN 0392-856X, 2015, Volume 33, Issue 1, pp. S53 - S57
Objective. Fibromyalgia (FM) is a syndrome characterised by chronic musculoskeletal pain, hyperalgesia on specific areas of tenderness (tender points) and by... 
Fibromyalgia | Sympathetic activity | Pain intensity | STIMULATION | sympathetic activity | pain intensity | RHEUMATOLOGY | POWER SPECTRAL-ANALYSIS | FREQUENCY-DOMAIN | BLOOD-PRESSURE | NERVE ACTIVITY | PATHOPHYSIOLOGY | RESPONSES | fibromyalgia | HEART-RATE-VARIABILITY | AUTONOMIC CARDIOVASCULAR CONTROL | HYPERTENSION | Blood Pressure | Predictive Value of Tests | Chronic Pain - diagnosis | Lung - innervation | Humans | Middle Aged | Cardiovascular System - innervation | Male | Muscle, Skeletal - innervation | Sympathetic Nervous System - physiopathology | Fibromyalgia - psychology | Pain Perception | Electrocardiography | Adult | Female | Electromyography | Chronic Pain - etiology | Blood Pressure Determination | Severity of Illness Index | Fibromyalgia - complications | Heart Rate | Respiratory Rate | Linear Models | Chronic Pain - psychology | Sympathetic Fibers, Postganglionic - physiopathology | Fibromyalgia - diagnosis | Baroreflex | Pain Threshold | Chronic Pain - physiopathology | Fibromyalgia - physiopathology | Pain Measurement
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13. Full Text Quantifying nerve architecture in murine and human airways using three-dimensional computational mapping
by Scott, Gregory D and Fryer, Allison D and Jacoby, David B
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 01/2013, Volume 48, Issue 1, pp. 10 - 16
The quantitative histological analysis of airway innervation using tissue sections is challenging because of the sparse and patchy distribution of nerves. Here... 
Nerve | Neuroplasticity | Three-dimensional | Modeling | Computational | SYSTEM | modeling | BIOCHEMISTRY & MOLECULAR BIOLOGY | WALLERIAN DEGENERATION | MECHANISMS | CELL BIOLOGY | FIBERS | three-dimensional | PAIN | NEUROPATHY | RESPIRATORY SYSTEM | nerve | ASTHMA | HYPERINNERVATION | computational | neuroplasticity | COUGH | Guinea Pigs | Humans | Intestines - innervation | Mice, Inbred C57BL | Nervous System - metabolism | Nervous System - anatomy & histology | Animals | Neuronal Plasticity | Respiratory System - innervation | Computer Simulation | Dogs | Skin - innervation | Female | Substance P - metabolism | Mice | Respiratory Mucosa - innervation | Models, Neurological | Esophagus - innervation | Imaging, Three-Dimensional | Models, Anatomic | Major Technical Advances
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