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ChemMedChem, ISSN 1860-7179, 07/2017, Volume 12, Issue 13, pp. 1022 - 1032
Acute lung injury (ALI) has a high lethality rate, and interleukin‐6 (IL‐6) and tumor necrosis factor‐α (TNF‐α) contribute most to tissue deterioration in... 
anti-inflammatory | thiazolo[3,2-a]pyrimidines | cytokines | acute lung injury | interleukins | MORTALITY | PYRIMIDINE-DERIVATIVES | CHEMISTRY, MEDICINAL | MACROPHAGES | SEPSIS | DISCOVERY | RESPIRATORY-DISTRESS-SYNDROME | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | AGENTS | INHIBITORS | INFLAMMATORY RESPONSE | Tumor Necrosis Factor-alpha - metabolism | Interleukin-6 - antagonists & inhibitors | Pyrimidines - chemical synthesis | Tumor Necrosis Factor-alpha - genetics | Thiazoles - administration & dosage | Thiazoles - therapeutic use | RNA, Messenger - metabolism | Antigens, CD - metabolism | Sepsis - drug therapy | Sepsis - metabolism | Acute Lung Injury - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Interleukin-6 - metabolism | Macrophages, Peritoneal - drug effects | Quantitative Structure-Activity Relationship | Interleukin-6 - genetics | Pyrimidines - administration & dosage | Mice, Inbred C57BL | Mice, Inbred ICR | Animals | Pneumonia - drug therapy | Thiazoles - chemical synthesis | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Pyrimidines - therapeutic use | Antigens, Differentiation, Myelomonocytic - metabolism | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Lipopolysaccharides - pharmacology | Macrophages, Peritoneal - metabolism | Pneumonia - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Acute respiratory distress syndrome | Pyrimidines | Interleukins | Anti-inflammatory drugs | Mitogens | Analysis | Drugs | Ventilators | Antiinflammatory agents | Interleukin | Lethality | Inflammation | Derivatives | Macrophages | Drug development | Lipopolysaccharides | Interleukin 6 | Inhibitors | Synthesis | Lungs | Tumor necrosis factor | Rodents | Attenuation | Tumor necrosis factor-TNF | Peritoneum
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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 3, pp. 583 - 592.e6
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The New England Journal of Medicine, ISSN 0028-4793, 08/2014, Volume 371, Issue 8, pp. 711 - 722
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