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Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64138
Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) is being evaluated in multiple clinical trials. Our current approach to... 
THERAPY | SPECIFICITY | PERSISTENCE | MULTIDISCIPLINARY SCIENCES | MALIGNANCIES | ADOPTIVE IMMUNOTHERAPY | TRANSPOSITION | Cell Proliferation | Antigen-Presenting Cells - cytology | Coculture Techniques | Humans | Mutant Chimeric Proteins - genetics | DNA Transposable Elements - immunology | Antigens, CD19 - genetics | Leukemia, B-Cell - therapy | T-Lymphocytes - transplantation | CD3 Complex - genetics | Interleukin-2 - immunology | CD28 Antigens - genetics | T-Lymphocytes - metabolism | Transposases - genetics | DNA Transposable Elements - genetics | Antigens, CD19 - immunology | Gene Transfer Techniques | Antigen-Presenting Cells - metabolism | Gene Expression | Immunotherapy, Adoptive - methods | Lymphocyte Activation | Hematopoietic Stem Cell Transplantation | Leukemia, B-Cell - pathology | Electroporation | Transposases - immunology | CD28 Antigens - immunology | Clinical Trials as Topic | Antigen-Presenting Cells - immunology | Interleukin-2 - genetics | T-Lymphocytes - cytology | CD3 Complex - immunology | K562 Cells | Mutant Chimeric Proteins - immunology | T-Lymphocytes - immunology | Leukemia, B-Cell - immunology | Genetic Therapy - methods | Antigens | Immunotherapy | Genetically modified organisms | Transplantation | T cells | Gene therapy | Hematopoietic stem cells | Cell culture | Pediatrics | Propagation | Interleukin | Adoptive immunotherapy | Clinical trials | Stem cell transplantation | Lymphocytes T | CD28 antigen | Adoptive transfer | Infusion | Transposition | Lymphocytes | Manufacturing | Genetic modification | Deoxyribonucleic acid--DNA | Autografts | Medical research | Cytomegalovirus | CD19 antigen | Risk groups | Cloning | Zebrafish | CD3 antigen | T cell receptors | Gene expression | Transposase | Hemopoiesis | Children & youth | Plasmids | Biopsy | Antigen-presenting cells | Quality control | Stem cells | Umbilical cord | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 30, pp. 25049 - 25059
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 05/2011, Volume 208, Issue 5, pp. 1001 - 1013
The T-box transcription factor T-bet is important for the differentiation of naive CD4(+) T helper cells (Th cells) into the Th1 phenotype. Much is known about... 
MEDICINE, RESEARCH & EXPERIMENTAL | SUPPRESSOR | TARGET GENES | COMMITMENT | INTERFERON-GAMMA | CYTOKINE SIGNALING-1 | SOCS-3 | IMMUNOLOGY | TRANSCRIPTION FACTOR GATA-3 | CELL-DIFFERENTIATION | FATE | PLASTICITY | Genetic Loci - genetics | Suppressor of Cytokine Signaling 1 Protein | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Genetic Loci - immunology | Th1 Cells - metabolism | Cell Differentiation - genetics | Proto-Oncogene Proteins c-bcl-6 - metabolism | Response Elements - genetics | T Cell Transcription Factor 1 - metabolism | Repressor Proteins - metabolism | Cell Line | Suppressor of Cytokine Signaling Proteins - immunology | Hepatocyte Nuclear Factor 1-alpha | Repressor Proteins - genetics | Suppressor of Cytokine Signaling Proteins - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Response Elements - immunology | T-Box Domain Proteins - metabolism | Mice, Knockout | T Cell Transcription Factor 1 - genetics | Proto-Oncogene Proteins c-bcl-6 - genetics | Autoimmunity - physiology | Cell Differentiation - immunology | Suppressor of Cytokine Signaling 3 Protein | Animals | Down-Regulation - immunology | Repressor Proteins - immunology | T Cell Transcription Factor 1 - immunology | Transcription, Genetic - immunology | Mice | Th1 Cells - cytology | Suppressor of Cytokine Signaling Proteins - metabolism | Transcription, Genetic - genetics | Proto-Oncogene Proteins c-bcl-6 - immunology
Journal Article
Cancer Research, ISSN 0008-5472, 08/2012, Volume 72, Issue 16, pp. 3949 - 3957
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 5, pp. 2471 - 2479
The interaction of integrin alpha(E)(CD103)beta(7), often expressed on tumor-infiltrating T lymphocytes, with its cognate ligand, the epithelial cell marker... 
GROWTH-FACTOR-BETA | LYTIC GRANULE POLARIZATION | TGF-BETA | PERIPHERAL LYMPHOCYTES | E-CADHERIN | IMMUNOLOGY | ALPHA(E)BETA INTEGRIN | INTRAEPITHELIAL LYMPHOCYTES | INTEGRIN GENE PROMOTER | MEDIATED REGULATION | RENAL-ALLOGRAFTS | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Antigens, CD - biosynthesis | Humans | Lung Neoplasms - metabolism | Transforming Growth Factor beta1 - metabolism | Smad3 Protein - immunology | Smad3 Protein - metabolism | Antigens, CD - genetics | Signal Transduction - immunology | Smad3 Protein - genetics | Transforming Growth Factor beta1 - immunology | NFATC Transcription Factors - immunology | Integrin alpha Chains - immunology | Smad2 Protein - genetics | HEK293 Cells | Antigens, Neoplasm - metabolism | CD8-Positive T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell - immunology | Response Elements - genetics | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Receptors, Antigen, T-Cell - metabolism | Antigens, Neoplasm - immunology | Jurkat Cells | NFATC Transcription Factors - metabolism | Smad2 Protein - metabolism | Signal Transduction - genetics | Transforming Growth Factor beta1 - genetics | Response Elements - immunology | Lung Neoplasms - immunology | Smad2 Protein - immunology | Integrin alpha Chains - biosynthesis | Receptors, Antigen, T-Cell - genetics | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | NFATC Transcription Factors - genetics
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2012, Volume 189, Issue 3, pp. 1467 - 1479
Journal Article