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1. Full Text The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
by Truyen Nguyen and Paul Nioi and Cecil B. Pickett
Journal of Biological Chemistry, ISSN 0021-9258, 05/2009, Volume 284, Issue 20, pp. 13291 - 13295
A major mechanism in the cellular defense against oxidative or electrophilic stress is activation of the Nrf2-antioxidant response element signaling pathway,... 
HUMAN NEUROBLASTOMA-CELLS | PROTEIN-KINASE-C | TRANSCRIPTION FACTOR NRF2 | PLANAR AROMATIC-COMPOUNDS | CUL3-BASED E3 LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | YA-SUBUNIT GENE | CREB-BINDING-PROTEIN | ANTIOXIDANT RESPONSE | SUBSTRATE ADAPTER PROTEIN | CONTROLLING INDUCIBLE EXPRESSION | Reactive Oxygen Species - metabolism | Cytoskeletal Proteins - genetics | Humans | Oxidative Stress - physiology | Gene Expression Regulation - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Antioxidants | Transcription, Genetic - physiology | Animals | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cytoskeletal Proteins - metabolism | NF-E2-Related Factor 2 - genetics | Signal Transduction - physiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | NF-E2-Related Factor 2 - biosynthesis | Response Elements - physiology | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Minireviews
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2. Full Text Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues
by De Cecco, Marco and Criscione, Steven W and Peterson, Abigail L and Neretti, Nicola and Sedivy, John M and Kreiling, Jill A
Aging, ISSN 1945-4589, 2013, Volume 5, Issue 12, pp. 867 - 883
Transposable elements (TEs) were discovered by Barbara McClintock in maize and have since been found to be ubiquitous in all living organisms. Transposition is... 
Aging | Epigenetics | Chromatin | Transposable elements | RHESUS-MONKEYS | DNA-DAMAGE RESPONSE | DOUBLE-STRAND BREAKS | L1 RETROTRANSPOSITION | LINE-1 RETROTRANSPOSITION | chromatin | CELLULAR SENESCENCE | epigenetics | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | RNA-SEQ | CALORIC RESTRICTION | GENE-EXPRESSION | transposable elements | DIFFERENTIAL EXPRESSION ANALYSIS | Caloric Restriction | Liver | RNA, Messenger - genetics | Gene Expression Regulation - physiology | RNA, Messenger - metabolism | Deoxyribonucleases - metabolism | Animals | DNA Transposable Elements - physiology | Aging - physiology | DNA Transposable Elements - genetics | Mice | Genome | Microsatellite Repeats
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3. Full Text Contribution of transposable elements in the plant's genome
by Sahebi, Mahbod and Hanafi, Mohamed M and van Wijnen, Andre J and Rice, David and Rafii, M.Y and Azizi, Parisa and Osman, Mohamad and Taheri, Sima and Bakar, Mohd Faizal Abu and Isa, Mohd Noor Mat and Noor, Yusuf Muhammad
Gene, ISSN 0378-1119, 07/2018, Volume 665, pp. 155 - 166
Plants maintain extensive growth flexibility under different environmental conditions, allowing them to continuously and rapidly adapt to alterations in their... 
Stress conditions | Plant development | TEs silencing | Gene expression | Transposable elements | TERMINAL-REPEAT RETROTRANSPOSONS | ARABIDOPSIS-THALIANA | INSERTION | DNA METHYLATION | EPIGENETIC CONTROL | GENE DUPLICATION | HISTONE METHYLATION | EVOLUTION | WIDE ANALYSIS | GENETICS & HEREDITY | MAIZE | Plants - metabolism | Transcription, Genetic - physiology | DNA Transposable Elements - physiology | Plants - genetics | Gene Expression Regulation, Plant - physiology | Genome, Plant - physiology | Response Elements - physiology | Anopheles | Chromatin | Transposons | Islamic law | Genes | Genomics | Plant genetics | Genetic research | Genomes | Plants | Genetic transcription | Index Medicus
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4. Full Text Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
by Muckenthaler, Martina U and Galy, Bruno and Hentze, Matthias W
Annual Review of Nutrition, ISSN 0199-9885, 2008, Volume 28, Issue 1, pp. 197 - 213
The regulation and maintenance of systemic iron homeostasis is critical to human health. Iron overload and deficiency diseases belong to the most common... 
Iron overload | mRNA | Posttranscriptional regulation | Iron deficiency | Hepcidin | iron overload | hepcidin | HEREDITARY HEMOCHROMATOSIS PROTEIN | DIETARY IRON | DIVALENT METAL TRANSPORTER-1 | GENETIC HEMOCHROMATOSIS | posttranscriptional regulation | NUTRITION & DIETETICS | MESSENGER-RNA | TRANSFERRIN RECEPTOR | MICROCYTIC ANEMIA | iron deficiency | TARGETED DELETION | HYPOXIA-INDUCIBLE FACTOR-1 | FERRITIN SYNTHESIS | Animals | Humans | Iron - deficiency | Homeostasis | Iron-Regulatory Proteins - physiology | Response Elements - physiology | Iron - blood
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5. Full Text Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor α to estrogen-responsive elements
by Hewitt, Sylvia C and Li, Yin and Li, Leping and Korach, Kenneth S
Journal of Biological Chemistry, ISSN 0021-9258, 01/2010, Volume 285, Issue 4, pp. 2676 - 2685
Estrogen enables uterine proliferation, which depends on synthesis of the IGF1 growth factor. This proliferation and IGF1 synthesis requires the estrogen... 
CROSS-TALK | BREAST-CANCER | STAT5B | CELLS | I GENE-TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | SIGNAL TRANSDUCERS | MOUSE UTERUS | EXPRESSION | TRANSGENIC MICE | Insulin-Like Growth Factor I - pharmacology | Humans | Gene Expression Regulation - physiology | Male | Insulin-Like Growth Factor I - genetics | Cell Division - drug effects | Mice, Knockout | Cell Division - physiology | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Transcription, Genetic - physiology | Animals | Estrogen Receptor alpha - genetics | Promoter Regions, Genetic - physiology | Uterus - physiology | Uterus - growth & development | Introns - physiology | Uterus - cytology | Estrogen Receptor alpha - metabolism | Female | Mice | Epithelial Cells - cytology | Estrogens - metabolism | Response Elements - physiology | Steroid | Transcription, Chromatin, and Epigenetics | Estrogen Receptor α | Growth Factors | Transcription | Hormones | DNA-binding Protein | Igf1 | DNA-binding Mutant | Insulin-like Growth Factor | ERE Sequences | Receptors | Uterus | Thyroid
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6. Full Text Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes
by Makiko Ohtsuji and Fumiki Katsuoka and Akira Kobayashi and Hiroyuki Aburatani and John D. Hayes and Masayuki Yamamoto
Journal of Biological Chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 48, pp. 33554 - 33562
Nrf1 is a member of the vertebrate Cap`n'Collar (CNC) transcription factor family that commonly contains a unique basic-leucine zipper domain. Among CNC family... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | METALLOTHIONEIN-I PROMOTER | EMBRYONIC LETHALITY | ENDOPLASMIC-RETICULUM | MICE | INDUCTION | CELL-SURVIVAL | TRANSCRIPTION FACTOR | EXPRESSION | OXIDATIVE STRESS-RESPONSE | SMALL MAF PROTEINS | Fatty Liver - genetics | Fatty Liver - metabolism | Antioxidants - metabolism | Metallothionein - biosynthesis | Gene Expression Regulation - physiology | Hepatocytes - metabolism | Nuclear Respiratory Factor 1 - genetics | Gene Knockdown Techniques | Mice, Knockout | Animals | Metallothionein - genetics | Leucine Zippers - physiology | Hepatitis - genetics | NF-E2-Related Factor 2 - metabolism | Hepatitis - metabolism | Nuclear Respiratory Factor 1 - metabolism | NF-E2-Related Factor 2 - genetics | Mice | Response Elements - physiology | Protein Structure, Tertiary - physiology
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7. Full Text p53 responsive elements in human retrotransposons
by Harris, C.R and Dewan, A and Zupnick, A and Normart, R and Gabriel, A and Prives, C and Levine, A.J and Hoh, J
Oncogene, ISSN 0950-9232, 11/2009, Volume 28, Issue 44, pp. 3857 - 3865
Long interspersed nuclear elements-1 (L1s) are highly repetitive DNA elements that are capable of altering the human genome through retrotransposition. To... 
LINE-1 | Genome stability | P53 | genome stability | CELLS | APOPTOSIS | DNA-BINDING | ACTIVATION | METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | L1 RETROTRANSPOSITION | IDENTIFICATION | p53 | CELL BIOLOGY | ONCOLOGY | SUPPRESSOR PROTEIN P53 | GENETICS & HEREDITY | GENE-EXPRESSION | Long Interspersed Nucleotide Elements - physiology | Ribonuclease III - genetics | Ribonuclease III - metabolism | Humans | RNA, Messenger - genetics | Tumor Suppressor Protein p53 - metabolism | Gene Expression Regulation - physiology | Genomic Instability - physiology | Genome, Human - physiology | Tumor Suppressor Protein p53 - genetics | RNA, Messenger - biosynthesis | Cell Line, Tumor | Models, Genetic | DNA Methylation - physiology | Response Elements - physiology | Evolution, Molecular | Physiological aspects | Retrotransposons | Tumor suppressor genes | Research | Tumor proteins | Proteins | Oncology | Genetics | Deoxyribonucleic acid--DNA | Binding sites
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8. Full Text Peroxisome proliferator activated receptor α (PPARα) and PPAR gamma coactivator (PGC-1α) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements
by Song, Shulan and Attia, Ramy R and Connaughton, Sara and Niesen, Melissa I and Ness, Gene C and Elam, Marshall B and Hori, Roderick T and Cook, George A and Park, Edwards A
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2010, Volume 325, Issue 1, pp. 54 - 63
Long chain fatty acids and pharmacologic ligands for the peroxisome proliferator activated receptor alpha (PPARα) activate expression of genes involved in... 
PGC-1α | PPARα | Carnitine palmitoyltransferase-1A (CPT-1A) | Pyruvate dehydrogenase kinase (PDK) | MESSENGER-RNA ABUNDANCE | PGC-1 alpha | FASTING RESPONSE | THYROID-HORMONE | NUCLEAR RECEPTORS | HMG-COA REDUCTASE | PPAR alpha | FATTY-ACIDS | TRANSCRIPTIONAL COACTIVATOR | DIFFERENTIAL REGULATION | PYRUVATE-DEHYDROGENASE KINASE-4 | CELL BIOLOGY | ENDOCRINOLOGY & METABOLISM | ENERGY-METABOLISM | Up-Regulation | Carnitine O-Palmitoyltransferase - genetics | Transcription Factors - physiology | RNA-Binding Proteins - physiology | Humans | Transcriptional Activation | Cells, Cultured | Molecular Sequence Data | Rats | Male | Rats, Sprague-Dawley | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Animals | Base Sequence | Carnitine O-Palmitoyltransferase - metabolism | PPAR alpha - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | PPAR alpha - metabolism | Response Elements - physiology | RNA-Binding Proteins - metabolism | Activated | Receptors | Genes | Chains | Oxidation | Fatty acids | Binding sites | Carnitine | pyruvate dehydrogenase kinase (PDK)
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9. Full Text Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: Direct cross-talk between phase I and II drug-metabolizing enzymes
by Miao, Weimin and Hu, Lianggao and Scrivens, P. James and Batist, Gerald
Journal of Biological Chemistry, ISSN 0021-9258, 05/2005, Volume 280, Issue 21, pp. 20340 - 20348
The aryl hydrocarbon receptor (AHR) and NF-E2 p45-related factor (NRF2) are two distinct transcription factors involved in the regulation of drug-metabolizing... 
OXIDATIVE STRESS | PLANAR AROMATIC-COMPOUNDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | AH RECEPTOR | SUBUNIT GENE | IDENTIFICATION | NAD(P)H-QUINONE OXIDOREDUCTASE | CANCER | CHEMOPREVENTIVE AGENTS | INDUCIBLE EXPRESSION | Molecular Sequence Data | Promoter Regions, Genetic - genetics | Immunosorbent Techniques | Polychlorinated Dibenzodioxins - pharmacology | Base Sequence | Gene Deletion | Cloning, Molecular | Trans-Activators - genetics | Transcription, Genetic | Electrophoretic Mobility Shift Assay | Response Elements - genetics | Xenobiotics - metabolism | Tumor Cells, Cultured | Response Elements - physiology | Liver Neoplasms, Experimental | Chromatin - chemistry | Inactivation, Metabolic - physiology | Mutagenesis, Site-Directed | Signal Transduction | Gene Expression Regulation | Receptors, Aryl Hydrocarbon - drug effects | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Aryl Hydrocarbon - physiology | Animals | NF-E2-Related Factor 2 | Mice
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10. Full Text Laminar flow induction of antioxidant response element-mediated genes in endothelial cells: A novel anti-inflammatory mechanism
by Chen, Xi-Lin and Varner, Signe E and Rao, Anjali S and Grey, Janice Y and Thomas, Suzanne and Cook, Christopher K and Wasserman, Martin A and Medford, Russell M and Jaiswal, Anil K and Kunsch, Charles
Journal of Biological Chemistry, ISSN 0021-9258, 01/2003, Volume 278, Issue 2, pp. 703 - 711
Atherosclerotic lesions preferentially develop in areas of the vasculature exposed to nonlaminar blood flow and low fluid shear stress, whereas laminar flow... 
ATHEROSCLEROTIC LESIONS | OXIDATIVE STRESS | CHAIN PROMOTER | FLUID SHEAR-STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEME OXYGENASE-1 | KNOCKOUT MICE | NF-KAPPA-B | TRANSCRIPTION FACTOR | SMOOTH-MUSCLE CELLS | ADHESION MOLECULE-1 EXPRESSION | Carrier Proteins - physiology | Endothelium, Vascular - cytology | DNA-Binding Proteins - physiology | Antioxidants - metabolism | Humans | Cells, Cultured | Gene Expression Regulation | Stress, Mechanical | NAD(P)H Dehydrogenase (Quinone) - genetics | Hemorheology | Trans-Activators - physiology | Membrane Proteins | Arteriosclerosis - prevention & control | Endothelium, Vascular - metabolism | Tumor Necrosis Factor-alpha - physiology | Heme Oxygenase-1 | NF-E2-Related Factor 2 | Transcription, Genetic | Vascular Cell Adhesion Molecule-1 - genetics | Inflammation - prevention & control | Response Elements - physiology | Heme Oxygenase (Decyclizing) - genetics | Blood Circulation
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11. Full Text An emerging player in the adaptive immune response: MicroRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes
by Curtale, Graziella and Citarella, Franca and Carissimi, Claudia and Goldoni, Marina and Carucci, Nicoletta and Fulci, Valerio and Franceschini, Debora and Meloni, Francesca and Barnaba, Vincenzo and Macino, Giuseppe
Blood, ISSN 0006-4971, 01/2010, Volume 115, Issue 2, pp. 265 - 273
Activation of the T cell-mediated immune response has been associated with changes in the expression of specific microRNAs (miRNAs). However, the role of... 
RHEUMATOID-ARTHRITIS | APOPTOSIS | GENE | COSTIMULATORY SIGNALS | SYNOVIAL TISSUE | FAS-LIGAND | CALCINEURIN | SENSITIVITY | LEUKEMIA | HEMATOLOGY | TRANSCRIPTIONAL REGULATION | Adaptive Immunity - physiology | Receptors, Antigen, T-Cell - metabolism | Jurkat Cells | Humans | Fas-Associated Death Domain Protein - metabolism | Gene Expression Regulation - physiology | Transcription Factor AP-1 - immunology | MicroRNAs - metabolism | Proto-Oncogene Proteins c-ets - immunology | MicroRNAs - immunology | Transcription Factor AP-1 - metabolism | Fas-Associated Death Domain Protein - immunology | Transcription, Genetic - physiology | Interleukin-2 - immunology | Cell Death - physiology | T-Lymphocytes - cytology | T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell - immunology | Signal Transduction - physiology | T-Lymphocytes - immunology | Proto-Oncogene Proteins c-ets - metabolism | Interleukin-2 - biosynthesis | Response Elements - physiology | Lymphocyte Activation - physiology
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