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Journal Article
Nature Medicine, ISSN 1078-8956, 04/2016, Volume 22, Issue 4, pp. 439 - 445
Journal Article
Genes and Development, ISSN 0890-9369, 08/2003, Volume 17, Issue 15, pp. 1835 - 1840
Several platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) family members display C-terminal protein motifs that confer... 
Pericyte | Cell retention | Retina | Mesangial cell | PDGF | Heparan sulphate proteoglycan | DIABETIC-RETINOPATHY | VEGF ISOFORMS | pericyte | ANGIOGENESIS | A-CHAIN | DEVELOPMENTAL BIOLOGY | mesangial cell | CELL BIOLOGY | cell retention | retina | IN-VIVO | GENETICS & HEREDITY | MICE | heparan sulphate proteoglycan | HEPARAN-SULFATE PROTEOGLYCANS | GROWTH-FACTOR | BINDING | SMOOTH-MUSCLE CELLS | Kidney - physiology | Vascular Endothelial Growth Factor A | Endothelial Growth Factors - metabolism | Microcirculation - metabolism | Retina - metabolism | Vascular Endothelial Growth Factors | Glomerulosclerosis, Focal Segmental - genetics | Molecular Sequence Data | Intercellular Signaling Peptides and Proteins - metabolism | Lymphokines - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Proto-Oncogene Proteins c-sis - genetics | Proto-Oncogene Proteins c-sis - metabolism | Retinal Degeneration - genetics | Pericytes - metabolism | Proteinuria - genetics | Amino Acid Motifs | Retina - physiology | Phenotype | Platelet-Derived Growth Factor - metabolism | Animals | Endothelium, Vascular - metabolism | Alleles | Mice | Models, Genetic | Mutation | Microscopy, Fluorescence | Cell Movement | Proteins | Blood platelets | Secretion | Analysis | Genetic research | Genetic aspects | Growth factors | Endothelium | Index Medicus | Research Communications | Glomerulosclerosis; Focal Segmental/genetics | Intercellular Signaling Peptides and Proteins/metabolism | Platelet-Derived Growth Factor/metabolism | Proto-Oncogene Proteins c-sis/genetics/metabolism | Proteinuria/genetics | Models; Genetic | Microcirculation/metabolism | Lymphokines/metabolism | Microscopy; Fluorescence | Pericytes/metabolism | Kidney/physiology | Protein Structure; Tertiary | Retinal Degeneration/genetics | Endothelial Growth Factors/metabolism | Endothelium; Vascular/metabolism | Retina/metabolism/physiology
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 128, Issue 5, pp. 961 - 975
Anaplastic lymphoma kinase (Alk) has been proposed to regulate neuronal development based on its expression pattern in vertebrates and invertebrates; however,... 
ANAPLASTIC LYMPHOMA KINASE | SYNAPTIC SPECIFICITY | NERVOUS-SYSTEM | NEURONAL DEVELOPMENT | PHOTORECEPTOR AXONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NON-HODGKINS-LYMPHOMA | VISUAL-SYSTEM | GLIAL-CELLS | ROLLING PEBBLES | LAYER-SELECTION | CELL BIOLOGY | Retina - metabolism | Retina - growth & development | Cadherins - metabolism | Protein-Tyrosine Kinases - metabolism | Male | Optic Lobe, Nonmammalian - growth & development | Drosophila Proteins - metabolism | Drosophila melanogaster - metabolism | Protein-Tyrosine Kinases - genetics | Anaplastic Lymphoma Kinase | Retina - cytology | Larva - growth & development | Muscle Proteins - metabolism | Eye - innervation | Female | Cell Adhesion Molecules, Neuronal - metabolism | Membrane Proteins - metabolism | Photoreceptor Cells, Invertebrate - cytology | Pupa - growth & development | Signal Transduction | Animals, Genetically Modified | Axons - metabolism | Eye - growth & development | Receptor Protein-Tyrosine Kinases | Animals | Eye Proteins - metabolism | Drosophila melanogaster - growth & development | Photoreceptor Cells, Invertebrate - metabolism | Drosophila | Index Medicus | Muscle Proteins/metabolism | Photoreceptors; Invertebrate/cytology/metabolism | Axons/metabolism | Larva/growth & development | Drosophila Proteins/metabolism | Animals; Genetically Modified | Optic Lobe/growth & development | Protein-Tyrosine Kinases/genetics/metabolism | Pupa/growth & development | Cell Adhesion Molecules; Neuronal/metabolism | Membrane Proteins/metabolism | Cadherins/metabolism | Drosophila melanogaster/growth & development/metabolism | Eye Proteins/metabolism | Eye/growth & development/innervation | Retina/cytology/growth & development/metabolism
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2017, Volume 58, Issue 12, pp. 5043 - 5055
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15579 - 15584
Journal Article
Circulation Research, ISSN 0009-7330, 10/2009, Volume 105, Issue 9, pp. 897 - 905
RATIONALE:Insulin-like growth factor binding protein (IGFBP)-3 modulates vascular development by regulating endothelial progenitor cell (EPC) behavior,... 
Insulin-like growth factor binding protein-3 | Vascular repair | Nitric oxide | Hematopoietic stem cells | nitric oxide | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | RAT RETINA | LOW-DENSITY-LIPOPROTEIN | RECEPTOR | ENDOTHELIAL-CELL APOPTOSIS | FACTOR-I | CHOROIDAL NEOVASCULARIZATION | vascular repair | SPHINGOSINE 1-PHOSPHATE | RETINOPATHY | PERIPHERAL VASCULAR DISEASE | hematopoietic stem cells | HEMATOLOGY | insulin-like growth factor binding protein-3 | Cell Proliferation | Mesenteric Arteries - physiopathology | Humans | Male | Green Fluorescent Proteins - genetics | Retinal Neovascularization - metabolism | Retinopathy of Prematurity - physiopathology | Vasodilation | Retinal Vessels - pathology | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Infant, Newborn | Cytoprotection | Disease Models, Animal | Animals, Newborn | Gene Transfer Techniques | Sphingomyelins - metabolism | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Rats | Mice, Transgenic | Mesenteric Arteries - metabolism | Cell Adhesion Molecules - metabolism | Rats, Sprague-Dawley | Cerebral Arteries - metabolism | Stem Cells - pathology | Mice | Retinopathy of Prematurity - metabolism | Endothelial Cells - pathology | Retinal Neovascularization - physiopathology | Retinal Neovascularization - pathology | Astrocytes - metabolism | Cell Movement | Insulin-Like Growth Factor Binding Protein 3 - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphoproteins - metabolism | Stem Cells - metabolism | Cell Death | Female | Microfilament Proteins - metabolism | Nitric Oxide Synthase Type III - metabolism | Ceramides - metabolism | Mice, Inbred C57BL | Cells, Cultured | Cerebral Arteries - physiopathology | Pregnancy | Animals | Retinal Vessels - physiopathology | Scavenger Receptors, Class B - metabolism | Nitric Oxide - metabolism | Retinopathy of Prematurity - pathology | Index Medicus | Vascular Repair | Hematopoietic Stem Cells
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36949 - e36949
Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1 beta-driven neuroinflammation in the pathogenesis of diabetic... 
ADHESION MOLECULE-1 | PROTEIN-KINASE-C | MICROGLIAL ACTIVATION | ENDOTHELIAL-CELLS | BIOLOGY | GENE-EXPRESSION | RETINOPATHY | INDUCTION | INTERLEUKIN-1 INDUCES INTERLEUKIN-1 | MULLER CELLS | BRAIN | Microglia - metabolism | Up-Regulation | Retina - metabolism | Rats, Wistar | Diabetes Mellitus, Experimental - genetics | Male | Interleukin-1beta - genetics | Glial Fibrillary Acidic Protein - metabolism | Hyperglycemia - genetics | Glucose - administration & dosage | Interleukin-1beta - metabolism | Protein Kinase C - metabolism | Diabetes Mellitus, Experimental - metabolism | Interleukin-1beta - antagonists & inhibitors | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rats | Protein Kinase C - antagonists & inhibitors | Random Allocation | Rats, Sprague-Dawley | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hyperglycemia - metabolism | alpha-Macroglobulins - metabolism | Animals | Endothelium - metabolism | Ceruloplasmin - metabolism | Glucose - metabolism | Neuroglia - metabolism | Astrocytes - metabolism | Ceruloplasmin | Diabetic retinopathy | Protein kinase C | Retinopathy | Pathogenesis | Streptozocin | Retina | Immunoblotting | Glucose | Hyperglycemia | Ischemia | Rodents | Enzyme-linked immunosorbent assay | Enzymes | Cytokines | Astrocytes | Abnormalities | Diabetes mellitus | Blood vessels | Inflammation | IL-1β | Endothelial cells | Endothelium | Microglia | Polymerase chain reaction | Brain research | Diabetes | Glia | Laboratory animals | Subcultures | Apoptosis | Index Medicus
Journal Article
Investigative ophthalmology & visual science, ISSN 0146-0404, 2012, Volume 53, Issue 6, pp. 2968 - 2977
PURPOSE. Retinopathy of prematurity (ROP) is a leading cause of blindness in children and is, in its most severe form, characterized by uncontrolled growth of... 
RETINAL NEOVASCULARIZATION | BLOCKERS | MOUSE MODEL | RAT RETINA | OPHTHALMOLOGY | INFANTILE HEMANGIOMAS | FACTOR EXPRESSION | PREMATURITY | INFANCY | ENDOTHELIAL GROWTH-FACTOR | Up-Regulation | Cell Proliferation | Angiopoietin-2 - genetics | Humans | Gene Expression Profiling | Retinal Neovascularization - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiopoietin-2 - metabolism | Dose-Response Relationship, Drug | Receptors, Vascular Endothelial Growth Factor - metabolism | Retina - cytology | Propranolol - administration & dosage | Injections, Subcutaneous | Retinal Neovascularization - prevention & control | Erythropoietin - metabolism | Receptors, Vascular Endothelial Growth Factor - genetics | Drug Evaluation, Preclinical | Receptors, Adrenergic, beta - metabolism | Adrenergic beta-Antagonists - administration & dosage | Infant, Newborn | Disease Models, Animal | RNA - metabolism | Animals, Newborn | Oxygen - toxicity | Enzyme-Linked Immunosorbent Assay | Administration, Oral | Injections, Intraperitoneal | Reverse Transcriptase Polymerase Chain Reaction | Angiopoietin-1 - genetics | Erythropoietin - genetics | Animals | Retinopathy of Prematurity - prevention & control | Mice | Retinopathy of Prematurity - metabolism | In Vitro Techniques | Endothelial Cells - drug effects | Index Medicus | Disease Models | Other Medical Sciences | Endothelial Cells/drug effects | Oxygen/toxicity | Drug Evaluation | Vascular Endothelial Growth Factor A/genetics/metabolism | Infant | Propranolol/administration & dosage | Adrenergic | Oral | Intraperitoneal | RNA/metabolism | Receptors | Retinopathy of Prematurity/metabolism/prevention & control | beta/metabolism | Preclinical | Adrenergic beta-Antagonists/administration & dosage | Drug | Administration | Retinal Neovascularization/metabolism/prevention & control | Subcutaneous | Angiopoietin-2/genetics/metabolism | Erythropoietin/genetics/metabolism | Retina/cytology | Angiopoietin-1/genetics/metabolism | Injections | Newborn | Annan medicin och hälsovetenskap | Animal | Dose-Response Relationship | Vascular Endothelial Growth Factor/genetics/metabolism
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2011, Volume 108, Issue 31, pp. E392 - E401
Journal Article
Diabetes, ISSN 0012-1797, 04/2018, Volume 67, Issue 4, pp. 769 - 781
Tight junctions (TJs) involve close apposition of transmembrane proteins between cells. Although TJ proteins have been studied in detail, the role of lipids is... 
STARGARDT-3 MACULAR DYSTROPHY | NEONATAL LETHALITY | ELOVL4 PROTEIN | ENDOCRINOLOGY & METABOLISM | BARRIER FUNCTION | RETINOPATHY | FATTY-ACIDS | ENDOTHELIAL-CELL PERMEABILITY | TANDEM MASS-SPECTROMETRY | OCCLUDIN PHOSPHORYLATION | EXPRESSION | Retina - metabolism | Humans | Claudin-5 - metabolism | Retinal Vessels - ultrastructure | Vascular Endothelial Growth Factor A - metabolism | Capillary Permeability - genetics | Occludin - metabolism | Endothelial Cells - ultrastructure | Cattle | Interleukin-1beta - metabolism | Diabetes Mellitus, Experimental - complications | Membrane Proteins - metabolism | Diabetic Retinopathy - etiology | Eye Proteins - genetics | Zonula Occludens-1 Protein - metabolism | Diabetes Mellitus, Experimental - metabolism | Tight Junctions - metabolism | Ceramides - metabolism | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Membrane Proteins - genetics | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Blood-Retinal Barrier - metabolism | Tight Junctions - ultrastructure | Animals | Eye Proteins - metabolism | Mice | Complications and side effects | Diabetic retinopathy | Diabetes | Research | Gene expression | Vascular endothelial growth factor | Risk factors | Retinopathy | Cytokines | Tight junctions | Diabetes mellitus | Lipids | Retina | Permeability | Fatty acids | Zonula occludens-1 protein | Membrane proteins | Proteins | Apposition | Ultrastructure | Index Medicus | Abridged Index Medicus | Complications | 0107
Journal Article