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American journal of human genetics, ISSN 0002-9297, 10/2017, Volume 101, Issue 4, pp. 552 - 563
The Sonic Hedgehog (SHH) pathway is a key signaling pathway orchestrating embryonic development, mainly of the CNS and limbs. In vertebrates, SHH signaling is... 
polymicrogyria | developmental defects | hypomorphic variants | congenital ataxia | ciliopathies | SUFU | Joubert syndrome | Sonic Hedgehog | molar tooth sign | GLI3 | Congenital ataxia | Hypomorphic variants | Developmental defects | Ciliopathies | Polymicrogyria | Molar tooth sign | SHH | SIGNALING PATHWAY | GENETICS & HEREDITY | PLANAR CELL POLARITY | CEREBELLAR DEVELOPMENT | GLI PROTEINS | MUTATIONS | KIF7 | MEDULLOBLASTOMA | PHENOTYPIC SPECTRUM | PRIMARY CILIA | Abnormalities, Multiple - pathology | Skin - metabolism | Humans | Zinc Finger Protein Gli3 | Hedgehog Proteins - metabolism | Male | Bone Diseases, Developmental - genetics | Mutation, Missense | Cerebellum - abnormalities | Bone Diseases, Developmental - pathology | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Kidney Diseases, Cystic - genetics | Craniofacial Abnormalities - pathology | Female | Child | Abnormalities, Multiple - genetics | Craniofacial Abnormalities - genetics | Repressor Proteins - metabolism | Skin - pathology | Fibroblasts - metabolism | Repressor Proteins - chemistry | Signal Transduction | Cells, Cultured | Repressor Proteins - genetics | Eye Abnormalities - genetics | Fibroblasts - pathology | Genes, Recessive | Sequence Analysis, DNA | Cerebellum - pathology | Kidney Diseases, Cystic - pathology | Nerve Tissue Proteins - metabolism | Eye Abnormalities - pathology | Retina - abnormalities | Retina - pathology | Cohort Studies | Embryonic development | Usage | Gene mutations | Analysis | Nucleotide sequencing | Research | Diagnosis | Children | Health aspects | DNA sequencing
Journal Article
2010, ISBN 9780849375569, xviii, 359
Book
Clinical & Experimental Ophthalmology, ISSN 1442-6404, 03/2009, Volume 37, Issue 2, pp. 223 - 231
Purpose:  The aim of this study is to investigate markers of inflammation and oxidative stress in an early model of diabetic retinopathy, correlate retinal and... 
pericyte | diabetic retinopathy | inflammation | microglia | oxidative stress | Diabetic retinopathy | Oxidative stress | Pericyte | Inflammation | Microglia | CELLS | ANGIOGENESIS | ANTIOXIDANTS | DEATH | DAMAGE | PATHWAY | DISEASE | OPHTHALMOLOGY | RETINOPATHY | Retina - drug effects | Diabetic Retinopathy - drug therapy | Inflammation - pathology | Microglia - metabolism | Diabetes Mellitus, Experimental - drug therapy | Retina - metabolism | Oxidative Stress | Rats, Wistar | Tumor Necrosis Factor-alpha - blood | Superoxide Dismutase - blood | Male | Diabetic Retinopathy - pathology | Immunoenzyme Techniques | Inflammation - metabolism | Pericytes - pathology | Microglia - pathology | Free Radical Scavengers - therapeutic use | Acetylcysteine - therapeutic use | Diabetes Mellitus, Experimental - metabolism | Fluorescent Antibody Technique, Indirect | Enzyme-Linked Immunosorbent Assay | Macrophages - pathology | Pericytes - metabolism | Rats | Biomarkers - blood | Diabetic Retinopathy - metabolism | Macrophages - metabolism | Animals | Endothelium, Vascular - metabolism | Diabetes Mellitus, Experimental - pathology | Endothelium, Vascular - pathology | Isoprostanes - blood | Pericytes, metabolism | Endothelium, Vascular, metabolism | Microglia, metabolism | Superoxide Dismutase, blood | Diabetic Retinopathy, pathology | Isoprostanes, blood | Tumor Necrosis Factor-alpha, blood | Acetylcysteine, therapeutic use | Endothelium, Vascular, pathology | Inflammation, metabolism | Inflammation, pathology | Diabetic Retinopathy, metabolism | Diabetes Mellitus, Experimental, drug therapy | Macrophages, pathology | Retina, drug effects | Retina, metabolism | Diabetes Mellitus, Experimental, pathology | Pericytes, pathology | Diabetic Retinopathy, drug therapy | Diabetes Mellitus, Experimental, metabolism | Biological Markers, blood | Macrophages, metabolism | Microglia, pathology | Free Radical Scavengers, therapeutic use | Streptozocin | Heme | Acetylcysteine | Superoxide dismutase | Superoxide | Ophthalmology | Universities and colleges | Macrophages | Vascular endothelial growth factor | Endothelium
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2018, Volume 67, Issue 9, pp. 1867 - 1879
Intermittent fasting (IF) protects against the development of metabolic diseases and cancer, but whether it can prevent diabetic microvascular complications is... 
DIABETIC-RETINOPATHY | BILE-ACID | CELLS | ACTIVATION | BACTERIA | OBESITY | METABOLISM | FARNESOID X RECEPTOR | C57BL/6 MICE | ENDOCRINOLOGY & METABOLISM | TAUROURSODEOXYCHOLIC ACID | Retina - drug effects | Leukocytes - pathology | Receptors, G-Protein-Coupled - metabolism | Colon - drug effects | Microvessels - metabolism | Microvessels - pathology | Colon - immunology | Male | Ganglia, Sensory - metabolism | Retina - immunology | Intestinal Mucosa - drug effects | Diabetic Retinopathy - complications | Retinal Vessels - pathology | Feces - microbiology | Intestinal Mucosa - immunology | Bacteroidetes - isolation & purification | Firmicutes - growth & development | Diabetic Retinopathy - immunology | Firmicutes - isolation & purification | Retinal Vessels - metabolism | Colon - pathology | Retinal Vessels - drug effects | Dysbiosis - therapy | Goblet Cells - metabolism | Colon - metabolism | Ganglia, Sensory - pathology | Diabetic Retinopathy - prevention & control | Gastrointestinal Microbiome - drug effects | Bile Acids and Salts - therapeutic use | Survival Analysis | Leukocytes - drug effects | Diabetes Mellitus, Type 2 - pathology | Dysbiosis - pathology | Retina - pathology | Intestinal Mucosa - pathology | Intestinal Mucosa - metabolism | Retina - metabolism | Diabetes Mellitus, Type 2 - microbiology | Ganglia, Sensory - drug effects | Goblet Cells - drug effects | Diabetic Retinopathy - pathology | Receptors, G-Protein-Coupled - agonists | Dysbiosis - microbiology | Microvessels - immunology | Ganglia, Sensory - immunology | Goblet Cells - immunology | Leukocytes - immunology | Retinal Vessels - immunology | Mice, Mutant Strains | Diabetes Mellitus, Type 2 - therapy | Bacteroidetes - immunology | Mice, Inbred DBA | Verrucomicrobia - growth & development | Verrucomicrobia - immunology | Diabetes Mellitus, Type 2 - complications | Fasting | Microvessels - drug effects | Firmicutes - immunology | Verrucomicrobia - isolation & purification | Dysbiosis - complications | Animals | Bacteroidetes - growth & development | Gastrointestinal Microbiome - immunology | Goblet Cells - pathology | Prevention | Diabetic retinopathy | Usage | Diet therapy | Low-calorie diet | Rattus | Rats | Health aspects | Complications | 0107
Journal Article
The American journal of pathology, ISSN 0002-9440, 2008, Volume 172, Issue 5, pp. 1411 - 1418
Journal Article
PloS one, ISSN 1932-6203, 01/2009, Volume 4, Issue 1, p. e4317
Journal Article