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1. Full Text Quantitative Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration
by Jia, Yali, PhD and Bailey, Steven T., MD and Wilson, David J., MD and Tan, Ou, PhD and Klein, Michael L., MD and Flaxel, Christina J., MD and Potsaid, Benjamin, PhD and Liu, Jonathan J., MS and Lu, Chen D., MS and Kraus, Martin F., MS and Fujimoto, James G., PhD and Huang, David, MD, PhD
Ophthalmology, ISSN 0161-6420, 2014, Volume 121, Issue 7, pp. 1435 - 1444
Purpose To detect and quantify choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD) using optical coherence tomography... 
Ophthalmology | AMPLITUDE-DECORRELATION ANGIOGRAPHY | MOTION-CORRECTION | DISEASES | MICROVASCULATURE | LASER-DOPPLER FLOWMETRY | DOMAIN OCT | OPHTHALMOLOGY | MICROCIRCULATION | RETINAL BLOOD-FLOW | INDOCYANINE GREEN ANGIOGRAPHY | SWEPT-SOURCE | Choroidal Neovascularization - diagnosis | Cross-Sectional Studies | Tomography, Optical Coherence | Humans | Male | Wet Macular Degeneration - physiopathology | Healthy Volunteers | Choroidal Neovascularization - physiopathology | Wet Macular Degeneration - diagnosis | Pilot Projects | Algorithms | Blood Flow Velocity | Aged, 80 and over | Female | Aged | Imaging, Three-Dimensional | Fluorescein Angiography | Macular degeneration | Electrical engineering | Computer science | Tomography | Neovascularization | Angiography | Index Medicus
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2. Full Text Embryonic stem cell trials for macular degeneration: a preliminary report
by Schwartz, Steven D, Prof and Hubschman, Jean-Pierre, MD and Heilwell, Gad, MD and Franco-Cardenas, Valentina, MD and Pan, Carolyn K, MD and Ostrick, Rosaleen M, MPH and Mickunas, Edmund, MS and Gay, Roger, PhD and Klimanskaya, Irina, PhD and Lanza, Robert, Dr
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9817, pp. 713 - 720
Summary Background It has been 13 years since the discovery of human embryonic stem cells (hESCs). Our report provides the first description of hESC-derived... 
Internal Medicine | TRANSLOCATION | MEDICINE, GENERAL & INTERNAL | RPE | MORPHOLOGY | RETINAL-PIGMENT EPITHELIUM | TRANSPLANTATION | Animals | Macular Degeneration - physiopathology | Macular Degeneration - therapy | Mice, Nude | Embryonic Stem Cells - transplantation | Humans | Immunosuppressive Agents - therapeutic use | Rats | Cell Differentiation | Mice | Visual Acuity | Retinal Pigment Epithelium - cytology | Macular degeneration | Care and treatment | Embryonic stem cells | Health aspects | Studies | Transplants & implants | Good Manufacturing Practice | Stem cells | Data collection | Family medical history | Medical screening | Index Medicus | Abridged Index Medicus
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3. Full Text Pigment Epithelial Detachment Followed by Retinal Cystoid Degeneration Leads to Vision Loss in Treatment of Neovascular Age-Related Macular Degeneration
by Schmidt-Erfurth, Ursula, MD and Waldstein, Sebastian M., MD and Deak, Gabor-Gyoergy, MD and Kundi, Michael, MD, PhD and Simader, Christian, MD
Ophthalmology, ISSN 0161-6420, 2015, Volume 122, Issue 4, pp. 822 - 832
Purpose Intravitreal antiangiogenic therapy is the major therapeutic breakthrough in neovascular age-related macular degeneration (AMD). Optical coherence... 
Ophthalmology | VISUAL-ACUITY | IMPACT | INTRAVITREAL RANIBIZUMAB | DISEASES | THERAPY | OPTICAL COHERENCE TOMOGRAPHY | VEGF | OPHTHALMOLOGY | DOSING REGIMEN | CHOROIDAL NEOVASCULARIZATION | Prospective Studies | Receptors, Vascular Endothelial Growth Factor - therapeutic use | Intravitreal Injections | Humans | Middle Aged | Recombinant Fusion Proteins - therapeutic use | Male | Wet Macular Degeneration - physiopathology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Retinal Pigment Epithelium - pathology | Retinal Detachment - diagnosis | Ranibizumab | Aged, 80 and over | Angiogenesis Inhibitors - therapeutic use | Female | Visual Acuity - physiology | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Tomography, Optical Coherence | Wet Macular Degeneration - diagnosis | Wet Macular Degeneration - drug therapy | Macular Edema - physiopathology | Macular Edema - diagnosis | Retinal Detachment - physiopathology | Subretinal Fluid | Aged | Blindness - etiology | Macular degeneration | Care and treatment | Drug approval | Analysis | Index Medicus
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4. Full Text Ultrahigh-Speed, Swept-Source Optical Coherence Tomography Angiography in Nonexudative Age-Related Macular Degeneration with Geographic Atrophy
by Choi, WooJhon, PhD and Moult, Eric M., BS and Waheed, Nadia K., MD and Adhi, Mehreen, MD and Lee, ByungKun, MS and Lu, Chen D., MS and de Carlo, Talisa E., BS and Jayaraman, Vijaysekhar, PhD and Rosenfeld, Philip J., MD, PhD and Duker, Jay S., MD and Fujimoto, James G., PhD
Ophthalmology, ISSN 0161-6420, 2015, Volume 122, Issue 12, pp. 2532 - 2544
Purpose To investigate ultrahigh-speed, swept-source optical coherence tomography (SSOCT) angiography for visualizing vascular changes in eyes with... 
Ophthalmology | EYES | CHORIOCAPILLARIS | VASCULATURE | RPE | OPHTHALMOLOGY | SOURCE OCT | BLOOD-FLOW | CHOROIDAL NEOVASCULARIZATION | HUMAN RETINA | Prospective Studies | Cross-Sectional Studies | Macular Degeneration - physiopathology | Geographic Atrophy - diagnosis | Tomography, Optical Coherence | Humans | Middle Aged | Choroid - blood supply | Geographic Atrophy - physiopathology | Male | Regional Blood Flow | Macular Degeneration - diagnosis | Retinal Vessels - pathology | Blood Flow Velocity | Aged, 80 and over | Adult | Female | Aged | Fluorescein Angiography | Macular degeneration | Electrical engineering | Computer science | Tomography | Angiography | Index Medicus
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5. Full Text Subretinal Visual Implant Alpha IMS – Clinical trial interim report
by Stingl, Katarina and Bartz-Schmidt, Karl Ulrich and Besch, Dorothea and Chee, Caroline K and Cottriall, Charles L and Gekeler, Florian and Groppe, Markus and Jackson, Timothy L and MacLaren, Robert E and Koitschev, Assen and Kusnyerik, Akos and Neffendorf, James and Nemeth, Janos and Naeem, Mohamed Adheem Naser and Peters, Tobias and Ramsden, James D and Sachs, Helmut and Simpson, Andrew and Singh, Mandeep S and Wilhelm, Barbara and Wong, David and Zrenner, Eberhart
Vision Research, ISSN 0042-6989, 06/2015, Volume 111, Issue Pt B, pp. 149 - 160
A subretinal visual implant (Alpha IMS, Retina Implant AG, Reutlingen, Germany) was implanted in 29 blind participants with outer retinal degeneration in an... 
Neuroprosthetics | Subretinal Implant Alpha IMS | Retinitis pigmentosa | Hereditary retinal diseases | Photoreceptor degeneration | Artificial vision | RETINAL DEGENERATION | SURVIVAL | FEASIBILITY | VISION | FOLLOW-UP | NEUROSCIENCES | PSYCHOLOGY | BLIND PATIENTS | THERAPY | TRANSCORNEAL ELECTRICAL-STIMULATION | OPHTHALMOLOGY | RETINITIS-PIGMENTOSA | PROSTHESIS | Visual Perception - physiology | Blindness - physiopathology | Humans | Middle Aged | Male | Electrodes, Implanted | Retinal Degeneration - physiopathology | Activities of Daily Living | Form Perception - physiology | Blindness - rehabilitation | Adult | Female | Aged | Blindness - etiology | Motion Perception - physiology | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Retinal Degeneration - complications | Clinical trials | Index Medicus
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6. Full Text Intravitreal Bevacizumab (Avastin) for Neovascular Age-Related Macular Degeneration
by Avery, Robert L and Pieramici, Dante J and Rabena, Melvin D and Castellarin, Alessandro A and Nasir, Ma’an A and Giust, Matthew J
Ophthalmology, ISSN 0161-6420, 2006, Volume 113, Issue 3, pp. 363 - 372.e5
To report the short-term safety, biologic effect, and a possible mechanism of action of intravitreal bevacizumab in patients with neovascular age-related... 
VERTEPORFIN | TISSUE-PLASMINOGEN ACTIVATOR | PHOTODYNAMIC THERAPY | PHARMACOKINETICS | FACTOR ANTIBODY FRAGMENT | INJECTION | COHERENCE TOMOGRAPHY FINDINGS | DISEASE | OPHTHALMOLOGY | ENDOTHELIAL GROWTH-FACTOR | SUBFOVEAL CHOROIDAL NEOVASCULARIZATION | Retina - drug effects | Choroidal Neovascularization - diagnosis | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Choroidal Neovascularization - etiology | Male | Retinal Detachment - drug therapy | Macular Degeneration - diagnosis | Macular Degeneration - drug therapy | Bevacizumab | Antibodies, Monoclonal, Humanized | Choroidal Neovascularization - drug therapy | Retinal Detachment - diagnosis | Aged, 80 and over | Vitreous Body | Female | Retrospective Studies | Antibodies, Monoclonal - immunology | Fluorescein Angiography | Macular Degeneration - physiopathology | Tomography, Optical Coherence | Fovea Centralis | Macular Degeneration - complications | Vascular Endothelial Growth Factor A - immunology | Visual Acuity | Choroidal Neovascularization - physiopathology | Pigment Epithelium of Eye | Injections | Antibodies, Monoclonal - administration & dosage | Papilledema - diagnosis | Aged | Retina - pathology | Papilledema - drug therapy | Macular degeneration | Physiological aspects | Eye diseases | Angiogenesis inhibitors | Index Medicus
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7. Full Text Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus
by Elliott H. Sohn and Hille W. van Dijk and Chunhua Jiao and Pauline H. B. Kok and Woojin Jeong and Nazli Demirkaya and Allison Garmager and Ferdinand Wit and Murat Kucukevcilioglu and Mirjam E. J. van Velthoven and J. Hans DeVries and Robert F. Mullins and Markus H. Kuehn and Reinier Otto Schlingemann and Milan Sonka and Frank D. Verbraak and Michael David Abràmoff
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2016, Volume 113, Issue 19, pp. E2655 - E2664
Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal diabetic neuropathy (RDN), characterized by inner retinal... 
Diabetic retinopathy | Retina | Diabetes | Optical coherence tomography | Neurodegeneration | optical coherence tomography | MULTIDISCIPLINARY SCIENCES | neurodegeneration | VASCULAR DAMAGE | DEATH | diabetic retinopathy | retina | MACULAR EDEMA | VISUAL FUNCTION | MOUSE MODEL | DISEASE | TYPE-1 | diabetes | LAYER THICKNESS | ENDOTHELIAL GROWTH-FACTOR | Microvessels - physiopathology | Neurodegenerative Diseases - pathology | Retinal Degeneration - diagnosis | Species Specificity | Humans | Mice, Inbred C57BL | Microvessels - pathology | Neurodegenerative Diseases - diagnosis | Male | Diabetic Retinopathy - pathology | Retinal Degeneration - physiopathology | Disease Progression | Diabetic Retinopathy - physiopathology | Diabetic Retinopathy - diagnosis | Animals | Neurodegenerative Diseases - physiopathology | Adult | Female | Mice | Retinal Degeneration - pathology | Longitudinal Studies | Blood vessels | Index Medicus | Biological Sciences | PNAS Plus
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8. Full Text The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD
by Datta, Sayantan and Cano, Marisol and Ebrahimi, Katayoon and Wang, Lei and Handa, James T
Progress in Retinal and Eye Research, ISSN 1350-9462, 09/2017, Volume 60, pp. 201 - 218
The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that interacts with photoreceptors on its apical side and with Bruch's... 
Oxidative stress | Age-related macular degeneration | Nrf2 | Mitochondrial dynamics | Complement | Inflammation | Retinal pigment epithelium | OUTER SEGMENT PHAGOCYTOSIS | C-REACTIVE PROTEIN | AGE-RELATED MACULOPATHY | REQUIRES MITOCHONDRIAL ROS | SENILE MACULAR DEGENERATION | COMPLEMENT FACTOR-H | HEPARIN-BINDING DOMAIN | MEMBRANE ATTACK COMPLEX | OPHTHALMOLOGY | SUBRETINAL DRUSENOID DEPOSITS | RETINAL-PIGMENT EPITHELIUM | Macular Degeneration - etiology | Macular Degeneration - physiopathology | Immunity, Innate - physiology | Humans | Oxidative Stress - physiology | Risk Factors | Phagocytosis - physiology | Retinal Pigment Epithelium - physiopathology | Mitochondria - physiology | Macular degeneration | Medical colleges | Blindness | Physiological aspects | Smoking | inflammation | retinal pigment epithelium | complement | oxidative stress | mitochondrial dynamics
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9. Full Text Retinal Degeneration in Choroideremia follows an Exponential Decay Function
by Aylward, James W and Xue, Kanmin and Patrício, Maria I and Jolly, Jasleen K and Wood, Jonathan C and Brett, Jonathan and Jasani, Kirti M and MacLaren, Robert E
Ophthalmology, ISSN 0161-6420, 07/2018, Volume 125, Issue 7, pp. 1122 - 1124
GENE | OPHTHALMOLOGY | Choroideremia - physiopathology | Optical Imaging | Choroideremia - diagnostic imaging | Tomography, Optical Coherence | Humans | Retina - physiopathology | Ophthalmoscopy | Male | Retinal Degeneration - physiopathology | Young Adult | Adolescent | Adult | Female | Retrospective Studies | Child | Longitudinal Studies | Retinal Degeneration - diagnostic imaging | Index Medicus
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