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American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 2016, Volume 311, Issue 3, pp. H738 - H749
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 7, pp. 5059 - 5069
Compromised clearance of all-trans-retinal (atRAL), a component of the retinoid cycle, increases the susceptibility of mouse retina to acute light-induced... 
VISUAL CYCLE | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | 5-HT1A RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE-C | IN-VIVO | RECESSIVE RETINITIS-PIGMENTOSA | GENE ABCR | BINDING-PROPERTIES | NEUTROPHIL NADPH-OXIDASE | Reactive Oxygen Species - metabolism | Receptor, Serotonin, 5-HT2A - genetics | Calcium - metabolism | Humans | NADPH Oxidases - metabolism | Corneal Dystrophies, Hereditary - genetics | Type C Phospholipases - metabolism | Retinaldehyde - metabolism | Alcohol Oxidoreductases - genetics | ATP-Binding Cassette Transporters - genetics | Corneal Dystrophies, Hereditary - pathology | ATP-Binding Cassette Transporters - metabolism | NADPH Oxidases - genetics | Signal Transduction | Light - adverse effects | Receptor, Muscarinic M3 - metabolism | Alcohol Oxidoreductases - metabolism | Corneal Dystrophies, Hereditary - metabolism | Receptor, Muscarinic M3 - genetics | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Mice, Knockout | Macular Degeneration - metabolism | Animals | Macular Degeneration - genetics | Type C Phospholipases - genetics | Mice | Inositol 1,4,5-Trisphosphate - genetics | Photoreceptor Cells, Vertebrate - metabolism | Receptor, Serotonin, 5-HT2A - metabolism | Inositol 1,4,5-Trisphosphate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Macular Degeneration - pathology | Molecular Bases of Disease | Vitamin A | Retinal metabolism | Vision | Reactive oxygen species (ROS) | Retinoid
Journal Article
Nature medicine, ISSN 1546-170X, 2016, Volume 22, Issue 4, pp. 439 - 445
Journal Article
Progress in retinal and eye research, ISSN 1350-9462, 2015, Volume 49, pp. 67 - 81
...) and subretinal or choroidal NV. Retinal NV occurs in a group of diseases referred to as ischemic retinopathies in which damage to retinal vessels results in retinal ischemia... 
Angiogenesis | Diabetic retinopathy | Platelet-derived growth factor | Age-related macular degeneration | TIE2 | Angiopoietins | Vascular endothelial-protein tyrosine phosphatase | Hypoxia-inducible factor-1 | Vascular endothelial growth factor | OCCLUSION 12-MONTH OUTCOMES | PROLIFERATIVE RETINOPATHY | FACTOR VEGF | SUBRETINAL NEOVASCULARIZATION | OCULAR NEOVASCULARIZATION | EPITHELIUM-DERIVED FACTOR | IN-VIVO | OPHTHALMOLOGY | DIABETIC MACULAR EDEMA | SIGNAL-TRANSDUCTION PATHWAY | ENDOTHELIAL GROWTH-FACTOR | Choroid Diseases - metabolism | Humans | Retinal Diseases - metabolism | Choroid Diseases - etiology | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-2 - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Neovascularization, Pathologic - etiology | Intercellular Signaling Peptides and Proteins - metabolism | Animals | Choroid Diseases - drug therapy | Retinal Diseases - etiology | Angiogenesis Inhibitors - therapeutic use | Mice | Neovascularization, Pathologic - metabolism | Retinal Diseases - drug therapy | Disease Models, Animal | Macular degeneration | Medical colleges | Analysis | Development and progression | Neovascularization | Ophthalmology | vascular endothelial growth factor | angiopoietins | hypoxia-inducible factor-1 | vascular endothelial-protein tyrosine phosphatase | platelet-derived growth factor | diabetic retinopathy | age-related macular degeneration
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2018, Volume 38, Issue 11, pp. 2691 - 2705
OBJECTIVE—Blood-CNS barrier defects are implicated in retinopathies, neurodegenerative diseases, stroke, and epilepsy, yet, the pathological mechanisms downstream of barrier defects remain incompletely understood... 
blood-brain barrier | endothelial cells | edema | diabetic retinopathy | inflammation | DIABETIC-RETINOPATHY | NORRIE-DISEASE | BLOOD-BRAIN-BARRIER | PROTEIN-COUPLED RECEPTOR | GENE-EXPRESSION | RETINAL BARRIER | VE-CADHERIN | PERIPHERAL VASCULAR DISEASE | SPROUTING ANGIOGENESIS | HEMATOLOGY | FAMILIAL EXUDATIVE VITREORETINOPATHY | CNS ANGIOGENESIS | Retinal Diseases - genetics | Cell Proliferation | Age Factors | Cadherins - metabolism | Immunoglobulins - immunology | Macular Edema - pathology | Complement System Proteins - immunology | Male | Retinal Diseases - metabolism | Diabetic Retinopathy - pathology | Antigens, CD - genetics | Basement Membrane - pathology | Antigens, CD - metabolism | Complement System Proteins - metabolism | Immunoglobulins - metabolism | Retinal Vessels - immunology | Retinal Vessels - pathology | Cellular Senescence | Tetraspanins - deficiency | Retinal Diseases - pathology | Female | Cadherins - genetics | Macular Edema - genetics | Tetraspanins - genetics | Blood-Retinal Barrier - immunology | Eye Diseases, Hereditary - pathology | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Genotype | Blood-Retinal Barrier - pathology | Macular Edema - metabolism | Basement Membrane - metabolism | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Eye Diseases, Hereditary - genetics | Mice, Knockout | Blood-Retinal Barrier - metabolism | Endothelial Cells - immunology | Phenotype | Animals | Familial Exudative Vitreoretinopathies | Endothelial Cells - pathology | Eye Diseases, Hereditary - metabolism | Retinal Neovascularization | 10195 | Basic Sciences
Journal Article
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2016, Volume 36, Issue 7, pp. 1328 - 1337
Objective-Plasma high-density lipoproteins have several putative antiatherogenic effects, including preservation of endothelial functions. This is thought to... 
atherosclerosis | endothelium | ATP-binding cassette transporters | ACTIVATION | NITRIC-OXIDE SYNTHASE | LINEAGE ANALYSIS | ADHESION MOLECULES | KNOCKOUT MICE | hypercholesterolemia | HIGH-DENSITY-LIPOPROTEIN | HEART-DISEASE | GENE-EXPRESSION | HDL CHOLESTEROL | CORONARY-ARTERY-DISEASE | Hypercholesterolemia | Endothelium | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Whole-Body Irradiation | ATP Binding Cassette Transporter, Subfamily G, Member 1 - deficiency | Atherosclerosis - genetics | Male | Monocytes - metabolism | Retinal Neovascularization - metabolism | Aortic Diseases - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Time Factors | Diet, High-Fat | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Retinal Neovascularization - genetics | Nitric Oxide Synthase Type III - metabolism | Aorta, Thoracic - pathology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Genetic Predisposition to Disease | Atherosclerosis - physiopathology | Endothelial Cells - metabolism | Tissue Culture Techniques | Aorta, Thoracic - metabolism | Aorta, Thoracic - physiopathology | Cholesterol - metabolism | Plaque, Atherosclerotic | Regional Blood Flow | Atherosclerosis - metabolism | Disease Progression | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Phenotype | Animals | ATP Binding Cassette Transporter 1 - deficiency | Endothelial Cells - pathology | Neovascularization, Physiologic | ATP Binding Cassette Transporter 1 - genetics | HDL | ABC transporters | angiogenesis
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 01/2017, Volume 13, Issue 2, pp. 72 - 74
Although regular physical activity can prevent or reduce the risk of many age-related diseases, the molecular mechanisms underpinning the protective effects of exercise are largely unknown... 
INTERLEUKIN-6 | SKELETAL-MUSCLE | ENDOCRINOLOGY & METABOLISM | Neoplasms - metabolism | Killer Cells, Natural | Colonic Neoplasms - prevention & control | Cardiovascular Diseases - prevention & control | Humans | Memory Disorders - metabolism | Male | Neoplasms - prevention & control | Diabetes Mellitus, Type 2 - metabolism | Retinal Degeneration - metabolism | Colonic Neoplasms - metabolism | Exercise Therapy | Retinal Degeneration - prevention & control | Breast Neoplasms - metabolism | Osteoporosis - metabolism | Female | Brain-Derived Neurotrophic Factor - metabolism | Polycystic Ovary Syndrome - prevention & control | Interleukin-6 - metabolism | Physical Conditioning, Animal | Cardiorespiratory Fitness | Polycystic Ovary Syndrome - metabolism | Cardiovascular Diseases - metabolism | Osteoporosis - prevention & control | Erectile Dysfunction - prevention & control | Osteoarthritis - prevention & control | Osteocalcin - metabolism | Diabetes Mellitus, Type 2 - prevention & control | Metabolic Diseases | Oxygen Consumption | Osteoarthritis - metabolism | Cathepsin B - metabolism | Breast Neoplasms - prevention & control | Erectile Dysfunction - metabolism | Memory Disorders - prevention & control | Animals | Exercise - physiology | Mice | Cell metabolism | Cellular proteins | Genetic aspects | Exercise | Health aspects | Muscle contraction
Journal Article