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Annual Review of Nutrition, ISSN 0199-9885, 08/2011, Volume 31, Issue 1, pp. 321 - 351
Journal Article
Arteriosclerosis thrombosis and vascular biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 7, pp. 1328 - 1337
Objective-Plasma high-density lipoproteins have several putative antiatherogenic effects, including preservation of endothelial functions. This is thought to... 
atherosclerosis | ATP-binding cassette transporters | Hypercholesterolemia | Endothelium | endothelium | ACTIVATION | NITRIC-OXIDE SYNTHASE | LINEAGE ANALYSIS | ADHESION MOLECULES | KNOCKOUT MICE | hypercholesterolemia | HIGH-DENSITY-LIPOPROTEIN | HEART-DISEASE | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HDL CHOLESTEROL | HEMATOLOGY | CORONARY-ARTERY-DISEASE | Whole-Body Irradiation | ATP Binding Cassette Transporter, Subfamily G, Member 1 - deficiency | Atherosclerosis - genetics | Male | Monocytes - metabolism | Retinal Neovascularization - metabolism | Aortic Diseases - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Time Factors | Diet, High-Fat | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Retinal Neovascularization - genetics | Nitric Oxide Synthase Type III - metabolism | Aorta, Thoracic - pathology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Genetic Predisposition to Disease | Atherosclerosis - physiopathology | Endothelial Cells - metabolism | Tissue Culture Techniques | Aorta, Thoracic - metabolism | Aorta, Thoracic - physiopathology | Cholesterol - metabolism | Plaque, Atherosclerotic | Regional Blood Flow | Atherosclerosis - metabolism | Disease Progression | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Phenotype | Animals | ATP Binding Cassette Transporter 1 - deficiency | Endothelial Cells - pathology | Neovascularization, Physiologic | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
Journal Article
Journal Article
Brain, ISSN 0006-8950, 06/2010, Volume 133, Issue 6, pp. 1591 - 1601
There has been growing interest in the use of retinal imaging for tracking disease progression in multiple sclerosis. However, systematic and detailed... 
Eye | Ocular pathology | Retinal periphlebitis | Multiple sclerosis | Inflammation | NERVE | retinal periphlebitis | PERIPHLEBITIS | OPTICAL COHERENCE TOMOGRAPHY | ABNORMALITIES | multiple sclerosis | INJURY | NEUROSCIENCES | CLINICAL NEUROLOGY | DEGENERATION | eye | NEURITIS | AXONAL LOSS | DEMYELINATION | ocular pathology | inflammation | GLAUCOMA | Neuroimaging | Immunohistochemistry | Brain | retinal degeneration | Retina | Leukocytes | Cell density | Atrophy | Iris | Computed tomography | Autopsy | Nerves | Tomography | Neurofilaments | Injuries | Astrocytes | Myelin | Neurons | Glial fibrillary acidic protein | Microglia | Neurological diseases | Retinal ganglion cells | Axons | Algorithms | Gliosis | Hypertrophy | Multiple Sclerosis, Relapsing-Remitting - pathology | Retinitis - pathology | Acute Disease | Retina - metabolism | Humans | Middle Aged | Multiple Sclerosis, Chronic Progressive - pathology | Male | Multiple Sclerosis, Chronic Progressive - metabolism | Retinal Degeneration - metabolism | Time Factors | Multiple Sclerosis - pathology | Adult | Female | Nervous System Diseases - metabolism | Retinal Degeneration - pathology | Chronic Disease | Retina - pathology | Multiple Sclerosis, Relapsing-Remitting - metabolism | Multiple Sclerosis - metabolism | Nervous System Diseases - pathology | Retinitis - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 2/2014, Volume 57, Issue 2, pp. 413 - 423
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2017, Volume 127, Issue 1, pp. 199 - 214
Outer retinal and renal glomerular functions rely on specialized vasculature maintained by VEGF that is produced by neighboring epithelial cells, the retinal... 
INTRAVITREAL INJECTION | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | PIGMENT EPITHELIAL-CELLS | MEDIATED INJURY | MACULAR DEGENERATION | FACTOR-H | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | GEOGRAPHIC ATROPHY | ENDOTHELIAL GROWTH-FACTOR | MEMBRANE-ATTACK-COMPLEX | Protein kinase C | Deposits | Retina | Complement | Antagonists | Cyclic AMP response element-binding protein | Endothelial cells | Kidney | Macular degeneration | Eye | Signal transduction | Complement factor H | Antagonism | Cell activation | Complement activation | Microvasculature | vascularization | Degeneration | thrombotic microangiopathy | retinal pigment epithelium | Vascular endothelial growth factor | Age | Retinal Pigment Epithelium - metabolism | Protein Kinase C-alpha - metabolism | Humans | Protein Kinase C-alpha - genetics | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Kidney Diseases - genetics | Thrombotic Microangiopathies - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Retinal Pigment Epithelium - pathology | Female | Eye Proteins - antagonists & inhibitors | Eye Proteins - genetics | Kidney Diseases - metabolism | Podocytes - metabolism | Thrombotic Microangiopathies - pathology | Kidney Diseases - pathology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Podocytes - pathology | Mice, Knockout | Cyclic AMP Response Element-Binding Protein - genetics | Macular Degeneration - metabolism | Animals | Complement Factor H - metabolism | Eye Proteins - metabolism | Macular Degeneration - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Aged | Mice | Thrombotic Microangiopathies - metabolism | Complement Factor H - genetics | Macular Degeneration - pathology | Neovascularization | Analysis | Proteins | Medical research | Edema | Rodents | Colleges & universities | Photoreceptors | Experiments | Patients | Research centers | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2009, Volume 284, Issue 22, pp. 15173 - 15183
Exposure to bright light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental animals, but the mechanism(s) remain unclear.... 
LIPOFUSCIN FLUOROPHORE | VISUAL CYCLE | OXIDATIVE STRESS | A2E | PHOTORECEPTOR OUTER SEGMENTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PIGMENTED EPITHELIAL-CELLS | MACULAR DEGENERATION | GENE ABCR | KNOCKOUT MICE | INDUCED DAMAGE | Enzymes | retinal degeneration | Retinopathy | Cross-breeding | Toxicity | Membrane permeability | Caspase | Retina | Chromophores | Retinoids | Acyltransferase | Light effects | Eye | Retinol dehydrogenase | Mitochondria | Cell activation | Cell death | Vision | Condensation products | Plasma membranes | Photoreceptors | ATP-binding protein | Genetic crosses | Poisoning | Retinal Diseases | Abca4 protein, mouse | Humans | Chromatography, High Pressure Liquid | Vitamin A | Rdh8 protein, mouse | Retinal Degeneration | Light | Mass Spectrometry | Aging | Chromatography, Liquid | Alcohol Oxidoreductases | retinol acetate | Cell Line | Ethanolamine | Acute Disease | Rhodopsin | Oxidation-Reduction | Cell Survival | Rats | Retinaldehyde | isorhodopsin | bcl-2-Associated X Protein | Index Medicus | ATP-Binding Cassette Transporters | Animals | Mice | Caspases | Apoptosis | Vitamin A - analogs & derivatives | Retinal Diseases - metabolism | Retinaldehyde - metabolism | Rhodopsin - metabolism | Retinal Degeneration - metabolism | Vitamin A - metabolism | Caspases - metabolism | Retina - enzymology | Retinal Diseases - etiology | ATP-Binding Cassette Transporters - metabolism | Retinal Diseases - pathology | Ethanolamine - metabolism | bcl-2-Associated X Protein - metabolism | Aging - pathology | Retinal Degeneration - pathology | Retina - pathology | Alcohol Oxidoreductases - deficiency
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2011, Volume 164, Issue 1, pp. 170 - 180
BACKGROUND AND PURPOSE Up‐regulation of thioredoxin interacting protein (TXNIP), an endogenous inhibitor of thioredoxin (Trx), compromises cellular antioxidant... 
peroxynitrite | retina | neuroprotection | verapamil | NMDA | neurodegeneration | TXNIP | apoptosis | retinal ganglion cells | Thioredoxin | DIABETIC-RETINOPATHY | OXIDATIVE STRESS | RAT RETINA | FACTOR-KAPPA-B | CALCIUM-CHANNEL BLOCKERS | NERVE GROWTH-FACTOR | OPEN-ANGLE GLAUCOMA | IN-VIVO | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | UP-REGULATED PROTEIN-1 | Neuroprotective Agents | Up-Regulation | Poly(ADP-ribose) Polymerases | Oxidative Stress | Neuroglia | TXNIP protein, rat | Male | Retina | Retinal Ganglion Cells | MAP Kinase Kinase 4 | NF-kappa B | Caspase 3 | 3-nitrotyrosine | p38 Mitogen-Activated Protein Kinases | Carrier Proteins | Tyrosine | Rats | Inflammation | Interleukin-1beta | Caspase Inhibitors | Poly(ADP-ribose) Polymerase Inhibitors | Rats, Sprague-Dawley | Tumor Necrosis Factor-alpha | Index Medicus | Animals | Verapamil | MAP Kinase Kinase Kinase 5 | Eye Diseases | Thioredoxins | Apoptosis | Retina - drug effects | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Retina - metabolism | Apoptosis - drug effects | Caspase 3 - metabolism | NF-kappa B - metabolism | Retinal Ganglion Cells - metabolism | Tyrosine - analogs & derivatives | Inflammation - metabolism | MAP Kinase Kinase 4 - metabolism | Neuroprotective Agents - pharmacology | Interleukin-1beta - metabolism | MAP Kinase Kinase 4 - antagonists & inhibitors | Thioredoxins - metabolism | Thioredoxins - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | MAP Kinase Kinase Kinase 5 - antagonists & inhibitors | Eye Diseases - pathology | Interleukin-1beta - antagonists & inhibitors | NF-kappa B - antagonists & inhibitors | Carrier Proteins - biosynthesis | Carrier Proteins - antagonists & inhibitors | Eye Diseases - metabolism | Up-Regulation - genetics | Verapamil - pharmacology | Carrier Proteins - genetics | Poly(ADP-ribose) Polymerases - metabolism | Tyrosine - metabolism | Carrier Proteins - metabolism | Eye Diseases - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Inflammation - genetics | Neuroglia - metabolism | Oxidative Stress - drug effects | Retinal Ganglion Cells - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article