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European Journal of Cancer, ISSN 0959-8049, 2017, Volume 79, pp. 214 - 225
Abstract Background High-grade serous ovarian cancer (HGSOC) causes 80% of all ovarian cancer (OC) deaths. In this setting, the role of cancer stem-like cells... 
Hematology, Oncology and Palliative Medicine | BRCA | Prognosis | ALDH1 | Cancer stem-like cell | Survival | Aldehyde dehydrogenase-1 | Ovarian cancer | CD133 | BRCA2 MUTATIONS | METAANALYSIS | MARKER | ALDEHYDE DEHYDROGENASE 1 | CHEMOTHERAPY | ONCOLOGY | POOR-PROGNOSIS | CLINICAL-TRIALS | ALDH1 EXPRESSION | CARCINOMA | Neoplasm, Residual - pathology | Humans | Middle Aged | Retinal Dehydrogenase - metabolism | Ovarian Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - enzymology | Neoplasm Recurrence, Local - pathology | Platinum Compounds - therapeutic use | Neoplasms, Glandular and Epithelial - mortality | Isoenzymes - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adult | Female | Neoplasm, Residual - mortality | Neoplasms, Glandular and Epithelial - pathology | Ubiquitin-Protein Ligases - metabolism | Neoplasm, Residual - enzymology | Ovarian Neoplasms - enzymology | Neoplasms, Glandular and Epithelial - enzymology | BRCA2 Protein - metabolism | AC133 Antigen - metabolism | Survival Analysis | Carcinoma, Ovarian Epithelial | Aged | Neoplastic Stem Cells - enzymology | Clonal Evolution | Antimitotic agents | Care and treatment | Relapse | Oncology, Experimental | Analysis | Research | Antineoplastic agents | Aldehydes | Health aspects | Cancer | Diseases
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 380, Issue 1, pp. 10 - 19
Highlights • Preclinical retinoblastoma models derived from heavily pretreated patients are scarce. • Novel patient-derived preclinical retinoblastoma models... 
Hematology, Oncology and Palliative Medicine | CRX | Xenograft | Metastasis | Retinoblastoma | Tumor model | INTRINSIC PONTINE GLIOMA | TUMOR | NEUROBLASTOMA | INTRAARTERIAL CHEMOTHERAPY | GD2 SYNTHASE | MESSENGER-RNA | MODELS | ONCOLOGY | EXPRESSION | CELL | Neoplasm Transplantation | Retinoblastoma - genetics | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Neoplasms, Experimental - enzymology | Retinal Neoplasms - pathology | Child, Preschool | Infant | RNA, Messenger - metabolism | Neoplasms, Experimental - pathology | Brain Neoplasms - secondary | Heterografts | Neoplasm Micrometastasis | N-Acetylgalactosaminyltransferases - genetics | Neoplasms, Experimental - genetics | Trans-Activators - genetics | Biomarkers, Tumor - metabolism | Female | N-Acetylgalactosaminyltransferases - metabolism | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Retinoblastoma - secondary | Brain Neoplasms - enzymology | Signal Transduction | RNA, Messenger - genetics | Brain Neoplasms - genetics | Homeodomain Proteins - genetics | Gene Expression Regulation, Enzymologic | Retinal Neoplasms - enzymology | Animals | Mice, Nude | Cell Line, Tumor | Trans-Activators - metabolism | Biomarkers, Tumor - genetics | Retinoblastoma - enzymology | Retinal Neoplasms - genetics | Cell Movement
Journal Article
Cell Stem Cell, ISSN 1934-5909, 11/2007, Volume 1, Issue 5, pp. 555 - 567
Journal Article
Journal Article
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7557, pp. 482 - 486
Disruption of epithelial polarity is a key event in the acquisition of neoplastic growth. JNK signalling is known to play an important part in driving the... 
RETINAL DEGENERATION | GENETIC SCREEN | ACTIVATION | ONCOGENIC RAS | MECHANISM | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR | CRUMBS COMPLEX | SUPERFAMILY | MELANOGASTER | EIGER | Neoplasms - metabolism | ras Proteins - genetics | Humans | Molecular Sequence Data | ras Proteins - metabolism | Apoptosis - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | MAP Kinase Signaling System | Drosophila melanogaster - metabolism | Membrane Proteins - deficiency | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Female | Membrane Proteins - metabolism | Disease Models, Animal | Receptors, Tumor Necrosis Factor - genetics | Cell Division - genetics | Receptors, Tumor Necrosis Factor - metabolism | Amino Acid Sequence | Receptors, Tumor Necrosis Factor - chemistry | Membrane Proteins - genetics | Drosophila melanogaster - cytology | Neoplasms - enzymology | Drosophila Proteins - chemistry | Cell Adhesion Molecules - metabolism | Cell Polarity - genetics | Animals | Membrane Proteins - chemistry | Drosophila Proteins - deficiency | Drosophila melanogaster - enzymology | Drosophila Proteins - genetics | Matrix Metalloproteinase 1 - metabolism | Neoplasm Invasiveness - genetics | Neoplasms - pathology | Proteins | Genotype & phenotype | Insects | Genes | Cloning | Apoptosis | Cell Polarity | Drosophila Proteins | ras Proteins | Neoplasm Invasiveness | Cell Adhesion Molecules | Matrix Metalloproteinase 1 | Neoplasms | Membrane Proteins | Life Sciences | Receptors, Tumor Necrosis Factor | Cell Transformation, Neoplastic | Cell Division | JNK Mitogen-Activated Protein Kinases | Development Biology | Drosophila melanogaster
Journal Article
Annals of Surgical Oncology, ISSN 1068-9265, 1/2016, Volume 23, Issue 1, pp. 163 - 170
Journal Article
Journal Article
STEM CELLS, ISSN 1066-5099, 03/2013, Volume 31, Issue 3, pp. 423 - 432
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65158
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are defined as a small population of cancer cells that have high tumorigenicity. Furthermore,... 
POPULATION | ALDEHYDE DEHYDROGENASE | MARKER | MULTIDISCIPLINARY SCIENCES | CARCINOMAS | CD133 EXPRESSION | DEFINES | DRUG-RESISTANCE | IDENTIFICATION | TUMORIGENESIS | TUMOR-INITIATING CELLS | Prognosis | Humans | Middle Aged | Retinal Dehydrogenase - metabolism | Ovarian Neoplasms - pathology | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - pathology | Ovarian Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Isoenzymes - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adult | Female | Gene Expression | Isoenzymes - genetics | Ovarian Neoplasms - diagnosis | Adenocarcinoma, Clear Cell - diagnosis | Retinal Dehydrogenase - genetics | Organ Specificity | Ovarian Neoplasms - enzymology | Cystadenocarcinoma, Serous - enzymology | Cell Line, Tumor | Adenocarcinoma, Clear Cell - pathology | Aged | Biomarkers, Tumor - genetics | Cystadenocarcinoma, Serous - diagnosis | Primary Cell Culture | Neoplasm Staging | Adenocarcinoma, Clear Cell - enzymology | Adenocarcinoma, Clear Cell - genetics | Adenocarcinoma | Immunohistochemistry | Medical colleges | Relapse | Oncology, Experimental | Development and progression | Research | Ovarian cancer | Diseases | Chemotherapy | Analysis | Cancer | Biotechnology | Ovarian carcinoma | Colorectal cancer | Metastasis | Aldehyde dehydrogenase | Metastases | Population | Invasiveness | Mortality | Gynecology | Tumorigenicity | Tumor cell lines | Gene expression | Obstetrics | Medicine | Studies | Pathology | Hospitals | Stem cells | Biomarkers
Journal Article