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Nature Neuroscience, ISSN 1097-6256, 09/2009, Volume 12, Issue 9, pp. 1159 - 1164
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 33, Issue 34, pp. 8771 - 8781
Abstract We previously reported that nanoceria can slow retinal degeneration in the tubby mouse for two weeks by multiple systemic injections. However, the... 
Advanced Basic Science | Dentistry | Retinal degeneration | Nanoceria | Longevity | Antioxidant | Gene expression | Tubby mouse | OXIDATIVE STRESS | MATERIALS SCIENCE, BIOMATERIALS | REDOX STATE | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | MACULAR DEGENERATION | ENDOPLASMIC-RETICULUM STRESS | OPSIN MISLOCALIZATION | CELL-DEATH | CERIUM OXIDE NANOPARTICLES | RETINITIS-PIGMENTOSA | Retina - drug effects | Retina - metabolism | Intravitreal Injections | Opsins - genetics | Photoreceptor Cells, Vertebrate - drug effects | Retinal Rod Photoreceptor Cells - metabolism | Retinal Degeneration - prevention & control | Cerium - therapeutic use | Retinal Cone Photoreceptor Cells - pathology | Retinal Rod Photoreceptor Cells - drug effects | Cerium - administration & dosage | Retinal Degeneration - genetics | Mice, Inbred C57BL | Retina - physiopathology | Retinal Degeneration - physiopathology | Opsins - analysis | Gene Expression Regulation - drug effects | Animals | Retinal Cone Photoreceptor Cells - drug effects | Mice | Oxidative Stress - drug effects | Photoreceptor Cells, Vertebrate - metabolism | Retinal Degeneration - pathology | Photoreceptor Cells, Vertebrate - pathology | Retina - pathology | Retinal Cone Photoreceptor Cells - metabolism | Retinal Rod Photoreceptor Cells - pathology | Antioxidants | Eye diseases | Biological products | Analysis | Genes | Index Medicus | longevity | antioxidant | retinal degeneration | tubby mouse | gene expression | nanoceria
Journal Article
Neuroscience, ISSN 0306-4522, 2015, Volume 316, pp. 109 - 121
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1976 - 18
Rhodopsin homeostasis is tightly coupled to rod photoreceptor cell survival and vision. Mutations resulting in the misfolding of rhodopsin can lead to... 
RESCUE | MUTANT RHODOPSIN | PHARMACOLOGICAL CHAPERONES | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DOMINANT | MUTATIONS | MONOCLONAL-ANTIBODIES | RETINITIS-PIGMENTOSA | STARGARDT-DISEASE | CELL-DEATH | Neuroprotective Agents - therapeutic use | NIH 3T3 Cells | Retinaldehyde - therapeutic use | Thiophenes - therapeutic use | Humans | Male | Retinal Degeneration - etiology | Protein Transport - drug effects | Retinal Rod Photoreceptor Cells - metabolism | Rhodopsin - metabolism | Alcohol Oxidoreductases - genetics | Neuroprotective Agents - pharmacology | Rhodopsin - agonists | ATP-Binding Cassette Transporters - genetics | Protein Folding - drug effects | HEK293 Cells | Female | Retinal Rod Photoreceptor Cells - drug effects | Disease Models, Animal | Retinal Rod Photoreceptor Cells - radiation effects | Retinal Degeneration - drug therapy | Light - adverse effects | Mice, Inbred C57BL | Thiophenes - pharmacology | Treatment Outcome | Protein Transport - genetics | Mice, Knockout | Animals | High-Throughput Screening Assays | Rhodopsin - genetics | Rhodopsin - antagonists & inhibitors | Retinaldehyde - pharmacology | Cell Line, Tumor | Mice | Mutation | Retinal Degeneration - pathology | Retinal Rod Photoreceptor Cells - pathology | Rhodopsin | Cell survival | Toxicity | Retinitis pigmentosa | Homeostasis | Cytotoxicity | Retina | Pharmacology | Light effects | Molecular chains | Mutants | Mammalian cells | Retinal degeneration | Photoreceptors | Retinitis | Degeneration | Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 2, pp. 372 - 385
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 2017, Volume 26, Issue 2, pp. 305 - 319
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121977 - e0121977
Purpose Inorganic catalytic nanoceria or cerium oxide nanoparticles (CeNPs) are bona fide antioxidants that possess regenerative radical scavenging activities... 
PROGRAMMED CELL-DEATH | INTRAVITREAL INJECTION | RETINAL DEGENERATION | APOPTOSIS | OXIDATIVE STRESS | CERIA NANOPARTICLES | MULTIDISCIPLINARY SCIENCES | TUBBY MICE | TRANSGENIC RAT | RETINITIS-PIGMENTOSA | IN-SITU | Intravitreal Injections | Apoptosis - drug effects | Photoreceptor Cells, Vertebrate - drug effects | Male | Photoreceptor Cells, Vertebrate - physiology | Nerve Degeneration - prevention & control | Rats, Mutant Strains | Retinal Cone Photoreceptor Cells - pathology | Lipid Peroxidation - drug effects | Female | Retinal Rod Photoreceptor Cells - drug effects | Retinitis Pigmentosa - physiopathology | Cerium - administration & dosage | Disease Models, Animal | Retinitis Pigmentosa - drug therapy | Retinal Cone Photoreceptor Cells - physiology | Rats | Nerve Degeneration - pathology | Animals | Metal Nanoparticles - administration & dosage | Retinal Rod Photoreceptor Cells - physiology | Antioxidants - administration & dosage | Retinal Cone Photoreceptor Cells - drug effects | Oxidative Stress - drug effects | Photoreceptor Cells, Vertebrate - pathology | Retinitis Pigmentosa - pathology | Retinal Rod Photoreceptor Cells - pathology | Proteins | Antioxidants | Physiological aspects | Cerium | Neovascularization | Health sciences | Oxidative stress | Neuroprotection | Diabetic retinopathy | Neurosciences | Animal models | Retinitis pigmentosa | Genes | Lipid peroxidation | Retina | Lipids | Biology | Catalytic activity | Vascularization | Nanoparticles | Angiogenesis | Cell cycle | Eye (anatomy) | Mathematical models | Degeneration | Oxidation | Catalysis | Cerium oxides | Peroxidation | Free radicals | Injection | Chemical compounds | Medicine | Isoprostanes | Cell death | Retinal degeneration | Photoreceptors | Retinitis | Mutation | Apoptosis | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, pp. e0182389 - e0182389
Journal Article