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1. Full Text Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
by Pearson, R.A and Gonzalez-Cordero, A and West, E.L and Ribeiro, J.R and Aghaizu, N and Goh, D and Sampson, R.D and Georgiadis, A and Waldron, P.V and Duran, Y and Naeem, A and Kloc, M and Cristante, E and Kruczek, K and Warre-Cornish, K and Sowden, J.C and Smith, A.J and Ali, R.R
Nature Communications, ISSN 2041-1723, 10/2016, Volume 7, Issue 1, pp. 13029 - 13029
Photoreceptor replacement by transplantation is proposed as a treatment for blindness. Transplantation of healthy photoreceptor precursor cells into diseased... 
PURKINJE NEURONS | HEMATOPOIETIC-CELLS | PROGENITOR CELLS | DEGENERATE RETINA | STEM-CELLS | VISUAL FUNCTION | MULTIDISCIPLINARY SCIENCES | RECIPIENT RETINAL ENVIRONMENT | GENE-THERAPY | LEBERS CONGENITAL AMAUROSIS | MAMMALIAN-CELLS | Green Fluorescent Proteins - metabolism | NIH 3T3 Cells | Retina - transplantation | Mice, Inbred C57BL | Retinal Diseases - therapy | Male | Retinal Rod Photoreceptor Cells - metabolism | Retinal Degeneration - metabolism | Stem Cell Transplantation | Microscopy, Confocal | Photoreceptor Cells, Vertebrate - transplantation | Animals | Female | Mice | Tissue Donors | RNA - metabolism | Index Medicus
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2. Full Text Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals
by Kim, Jung-Woong and Yang, Hyun-Jin and Oel, Adam Phillip and Brooks, Matthew John and Jia, Li and Plachetzki, David Charles and Li, Wei and Allison, William Ted and Swaroop, Anand
Developmental Cell, ISSN 1534-5807, 06/2016, Volume 37, Issue 6, pp. 520 - 532
Vertebrate ancestors had only cone-like photoreceptors. The duplex retina evolved in jawless vertebrates with the advent of highly photosensitive rod-like... 
TRANSCRIPTION FACTORS | COLOR-VISION | CELLS | TEMPORAL EXPRESSION | ZEBRAFISH | VISUAL PIGMENTS | VERTEBRATE PHOTORECEPTORS | NRL | DEVELOPMENTAL BIOLOGY | MOUSE RETINA | PRECURSORS | CELL BIOLOGY | Mammals - genetics | Retinal Cone Photoreceptor Cells - radiation effects | Chromatin - metabolism | Mammals - metabolism | Basic-Leucine Zipper Transcription Factors - metabolism | Retinal Rod Photoreceptor Cells - radiation effects | Epigenesis, Genetic - radiation effects | Retinal Rod Photoreceptor Cells - metabolism | Zebrafish - embryology | Regulatory Sequences, Nucleic Acid - genetics | Cell Lineage - radiation effects | Night Vision - radiation effects | Biological Evolution | Animals | Gene Expression Regulation, Developmental - radiation effects | Ultraviolet Rays | Eye Proteins - metabolism | Chickens | Light | Zebrafish - metabolism | Opsins - metabolism | Mice | Retinal Cone Photoreceptor Cells - metabolism | Cell Lineage - genetics | Genetic research | Epigenetic inheritance | Evolutionary biology | Developmental biology | Neurophysiology | Index Medicus
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3. Full Text Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina
by Lakowski, Jorn and Gonzalez‐Cordero, Anai and West, Emma L and Han, Ya‐Ting and Welby, Emily and Naeem, Arifa and Blackford, Samuel J. I and Bainbridge, James W. B and Pearson, Rachael A and Ali, Robin R and Sowden, Jane C
STEM CELLS, ISSN 1066-5099, 08/2015, Volume 33, Issue 8, pp. 2469 - 2482
Loss of photoreceptors due to retinal degeneration is a major cause of untreatable blindness. Cell replacement therapy, using pluripotent stem cell‐derived... 
Surface antigens | Retinal dystrophies | Blindness | Retina | Transplantation | Embryonic stem cells | Photoreceptor cells | PROGENITOR CELLS | ROD | PIGMENTOSA | CELL & TISSUE ENGINEERING | CELL BIOLOGY | DEGENERATE RETINA | REPAIR | INTEGRATION | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-THERAPY | GENERATION | MOUSE RETINA | CONE | HEMATOLOGY | Stem Cell Transplantation | Animals | Retinal Rod Photoreceptor Cells - transplantation | Humans | Retinal Degeneration - therapy | Antigens, Differentiation - metabolism | Mice | Retinal Rod Photoreceptor Cells - metabolism | Retinal Degeneration - metabolism | Mouse Embryonic Stem Cells - metabolism | Bone marrow | Transplants & implants | Stem cells | Index Medicus | Regenerative Medicine
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4. Full Text Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision
by Altimus, Cara M and Zhao, Haiqing and Badea, Tudor C and Yau, King-Wai and Ecker, Jennifer L and Barnard, Alun R and Lall, Gurprit S and Hankins, Mark W and Berson, David M and Haq, Shafiqul and Lucas, Robert J and Güler, Ali D and Hattar, Samer and Liao, Hsi-Wen and Cahill, Hugh
Nature, ISSN 0028-0836, 05/2008, Volume 453, Issue 7191, pp. 102 - 105
Rod and cone photoreceptors detect light and relay this information through a multisynaptic pathway to the brain by means of retinal ganglion cells (RGCs).... 
RETINAL GANGLION-CELLS | RESPONSES | SUPRACHIASMATIC NUCLEUS | MULTIDISCIPLINARY SCIENCES | LIGHT | MOUSE | KNOCKOUT MICE | PROJECTIONS | PHOTORECEPTORS | Motor Activity - physiology | Pupil - physiology | Reflex - physiology | Retinal Rod Photoreceptor Cells - metabolism | Retinal Ganglion Cells - metabolism | Vision, Ocular - radiation effects | Brain - metabolism | Retinal Ganglion Cells - cytology | Vision, Ocular - physiology | Rod Opsins - genetics | Light | Rod Opsins - metabolism | Circadian Rhythm - radiation effects | Rod Opsins - deficiency | Visual Acuity - physiology | Cues | Electroretinography | Brain - cytology | Mice, Inbred C57BL | Reflex - radiation effects | Circadian Rhythm - physiology | Mice, Knockout | Animals | Pupil - radiation effects | Mice | Retinal Cone Photoreceptor Cells - metabolism | Retina | Rodents | Cells | Index Medicus
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5. Full Text Rod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment
by Thomas Burgoyne and Ingrid P. Meschede and Jemima J. Burden and Maryse Bailly and Miguel C. Seabra and Clare E. Futter
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 52, pp. 15922 - 15927
The outer segments of vertebrate rod photoreceptors are renewed every 10 d. Outer segment components are transported from the site of synthesis in the inner... 
Disc renewal | Rod photoreceptors | Rhodopsin | Protocadherin | CONNECTING CILIUM | PROTEIN | disc renewal | rod photoreceptors | PHOTORECEPTOR OUTER SEGMENTS | MULTIDISCIPLINARY SCIENCES | PIGMENT-EPITHELIUM | rhodopsin | HAIR-CELLS | MORPHOGENESIS | TRANSPORT | ANKLE-LINK COMPLEX | protocadherin | LEADING-EDGE | CYTOCHALASIN-D | Eye - metabolism | Retinal Rod Photoreceptor Cells - ultrastructure | Cadherins - metabolism | Eye - ultrastructure | Rod Cell Outer Segment - metabolism | Electron Microscope Tomography | Mice, Inbred C57BL | Munc18 Proteins - metabolism | Retinal Photoreceptor Cell Inner Segment - metabolism | Retinal Photoreceptor Cell Inner Segment - ultrastructure | Cell Membrane - ultrastructure | Photoreceptor Cells - ultrastructure | Retinal Rod Photoreceptor Cells - metabolism | Rhodopsin - metabolism | Microscopy, Immunoelectron | Cryoelectron Microscopy | Nerve Tissue Proteins - metabolism | Animals | Eye Proteins - metabolism | Rod Cell Outer Segment - ultrastructure | Photoreceptor Cells - metabolism | Qa-SNARE Proteins - metabolism | Cell Membrane - metabolism | Photoreceptors | Cell membranes | Research | Proteins | Polymerization | Tomography | Plasma | Membranes | Electrons | Index Medicus | Biological Sciences
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6. Full Text Transcriptome Dynamics of Developing Photoreceptors in Three‐Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
by Kaewkhaw, Rossukon and Kaya, Koray Dogan and Brooks, Matthew and Homma, Kohei and Zou, Jizhong and Chaitankar, Vijender and Rao, Mahendra and Swaroop, Anand
STEM CELLS, ISSN 1066-5099, 12/2015, Volume 33, Issue 12, pp. 3504 - 3518
The derivation of three‐dimensional (3D) stratified neural retina from pluripotent stem cells has permitted investigations of human photoreceptors. We have... 
Retina | Three‐dimensional organoid culture | Global gene profiling | Next generation sequencing | Human rod and cone photoreceptors | Stem cells | Three-dimensional organoid culture | MOUSE | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | PLURIPOTENT STEM-CELLS | EXPRESSION PATTERNS | LEUCINE-ZIPPER NRL | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NEURAL RETINA | HEMATOLOGY | HOMEOBOX GENE | HORMONE-RECEPTOR | PRECURSOR CELLS | EYE DEVELOPMENT | Cell Line | Human Embryonic Stem Cells - metabolism | Antigens, Differentiation - biosynthesis | Human Embryonic Stem Cells - cytology | Humans | Retinal Cone Photoreceptor Cells - cytology | Retinal Rod Photoreceptor Cells - cytology | Transcriptome | Cell Differentiation | Retinal Rod Photoreceptor Cells - metabolism | Retinal Cone Photoreceptor Cells - metabolism | Eye Proteins - biosynthesis | Immunohistochemistry | Rhodopsin | RNA | Genes | Photographic industry | Gene expression | Cell differentiation | Embryonic stem cells | Photoreceptors | Index Medicus | Translational and Clinical Research
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7. Full Text The Proteome of the Mouse Photoreceptor Sensory Cilium Complex
by Qin Liu and Glenn Tan and Natasha Levenkova and Tiansen Li and Edward N. Pugh, Jr and John J. Rux and David W. Speicher and Eric A. Pierce
Molecular & Cellular Proteomics, ISSN 1535-9476, 08/2007, Volume 6, Issue 8, pp. 1299 - 1317
Primary cilia play critical roles in many aspects of biology. Specialized versions of primary cilia are involved in many aspects of sensation. The single... 
RETINAL DEGENERATION | LEBER CONGENITAL AMAUROSIS | ROD OUTER SEGMENTS | CILIARY-DISEASE GENES | USHER-SYNDROME TYPE-1 | BIOCHEMICAL RESEARCH METHODS | BARDET-BIEDL-SYNDROME | BASAL BODY DYSFUNCTION | CGMP-GATED CHANNEL | INTRAFLAGELLAR TRANSPORT | RETINITIS-PIGMENTOSA | Animals | Rod Cell Outer Segment - metabolism | Cytoskeletal Proteins - genetics | Mice, Inbred C57BL | Cytoskeletal Proteins - metabolism | Mice | Retinal Rod Photoreceptor Cells - metabolism | Proteome - metabolism | Retinal Cone Photoreceptor Cells - metabolism | Cilia - metabolism | Index Medicus
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8. Full Text Developing Rods Transplanted into the Degenerating Retina of Crx‐Knockout Mice Exhibit Neural Activity Similar to Native Photoreceptors
by Homma, Kohei and Okamoto, Satoshi and Mandai, Michiko and Gotoh, Norimoto and Rajasimha, Harsha K and Chang, Yi‐Sheng and Chen, Shan and Li, Wei and Cogliati, Tiziana and Swaroop, Anand and Takahashi, Masayo
STEM CELLS, ISSN 1066-5099, 06/2013, Volume 31, Issue 6, pp. 1149 - 1159
Replacement of dysfunctional or dying photoreceptors offers a promising approach for retinal neurodegenerative diseases, including age‐related macular... 
Retinal photoreceptors | Induced pluripotent stem cells | Calcium flux | Cell transplantation | AGE-RELATED MACULOPATHY | MACULAR DEGENERATION | DEFICIENT MICE | INFRARED FLUORESCENT PROTEINS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | CONE PHOTORECEPTORS | ONCOLOGY | PHASE-I TRIAL | VISUAL FUNCTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EMBRYONIC STEM-CELLS | HEMATOLOGY | LEBERS CONGENITAL AMAUROSIS | NA+ ACTION-POTENTIALS | Membrane Potentials - genetics | Retina - metabolism | Basic-Leucine Zipper Transcription Factors - metabolism | Calcium - metabolism | Homeodomain Proteins - metabolism | Green Fluorescent Proteins - genetics | Retinal Rod Photoreceptor Cells - metabolism | Photoreceptor Cells, Vertebrate - physiology | Retinal Degeneration - metabolism | Stem Cell Transplantation | Cell Differentiation - genetics | Trans-Activators - genetics | Eye Proteins - genetics | Induced Pluripotent Stem Cells - metabolism | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Induced Pluripotent Stem Cells - physiology | Retinal Degeneration - genetics | Mice, Inbred C57BL | Cells, Cultured | Basic-Leucine Zipper Transcription Factors - genetics | Retinal Degeneration - physiopathology | Homeodomain Proteins - genetics | Mice, Knockout | Retina - physiology | Animals | Retinal Rod Photoreceptor Cells - transplantation | Eye Proteins - metabolism | Retinal Degeneration - therapy | Retinal Rod Photoreceptor Cells - physiology | Trans-Activators - metabolism | Mice | Photoreceptor Cells, Vertebrate - metabolism | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - genetics | Macular degeneration | Nervous system diseases | Rhodopsin | Neurosciences | Developmental biology | Analysis | Stem cells | Physiological aspects | Fluorescence | Exhibitions | Photographic industry | Cyanides | Retina | Index Medicus
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9. Full Text Otx2 and Onecut1 Promote the Fates of Cone Photoreceptors and Horizontal Cells and Repress Rod Photoreceptors
by Emerson, Mark M and Surzenko, Natalia and Goetz, Jillian J and Trimarchi, Jeffrey and Cepko, Constance L
Developmental Cell, ISSN 1534-5807, 07/2013, Volume 26, Issue 1, pp. 59 - 72
Cone photoreceptors carry out phototransduction in daylight conditions and provide the critical first step in color vision. Despite their importance, little is... 
PROGENITOR CELLS | TEMPORAL EXPRESSION | CHICKEN RETINA | MOUSE RETINAL DEVELOPMENT | IN-VIVO | GENE-EXPRESSION | DEVELOPMENTAL BIOLOGY | DIFFERENTIATION | TRANSCRIPTION FACTOR NRL | MAMMALIAN RETINA | PRECURSORS | CELL BIOLOGY | Retina - metabolism | Otx Transcription Factors - metabolism | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Thyroid Hormone Receptors beta - genetics | Chickens - metabolism | Retina - cytology | Gene Expression Regulation, Developmental | Otx Transcription Factors - genetics | Transcription, Genetic | Thyroid Hormone Receptors beta - metabolism | Hepatocyte Nuclear Factor 6 - metabolism | RNA, Messenger - genetics | Electroporation - methods | Chick Embryo | Mice, Knockout | Cell Lineage | Animals | Hepatocyte Nuclear Factor 6 - genetics | Regulatory Elements, Transcriptional | Retinal Cone Photoreceptor Cells - cytology | Retinal Rod Photoreceptor Cells - cytology | Mice | Retinal Cone Photoreceptor Cells - metabolism | Index Medicus
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10. Full Text Differentiation of Induced Pluripotent Stem Cells of Swine into Rod Photoreceptors and Their Integration into the Retina
by Zhou, Liang and Wang, Wei and Liu, Yongqing and de Castro, Juan Fernandez and Ezashi, Toshihiko and Telugu, Bhanu Prakash V.L and Roberts, R. Michael and Kaplan, Henry J and Dean, Douglas C
STEM CELLS, ISSN 1066-5099, 06/2011, Volume 29, Issue 6, pp. 972 - 980
Absence of a regenerative pathway for damaged retina following injury or disease has led to experiments using stem cell transplantation for retinal repair, and... 
Photoreceptor differentiation | Swine retina | Induced pluripotent stem cells | Retinal transplantation | PROGENITOR CELLS | RABBIT RETINA | MOUSE | MECHANISMS | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | REPAIR | DISEASES | ONCOLOGY | ALLORECIPIENTS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENERATION | HEMATOLOGY | IODOACETIC ACID | Retina - drug effects | Coculture Techniques | Induced Pluripotent Stem Cells - transplantation | Cells, Cultured | Proteoglycans - metabolism | Retinal Rod Photoreceptor Cells - metabolism | Rhodopsin - metabolism | Embryoid Bodies - metabolism | Collagen - metabolism | Tubulin - metabolism | Animals | Embryoid Bodies - cytology | Retinol-Binding Proteins - metabolism | Swine | Retinal Rod Photoreceptor Cells - cytology | Antigens, Differentiation - metabolism | Cell Differentiation | Cell Culture Techniques | Laminin - metabolism | Induced Pluripotent Stem Cells - cytology | Retina - pathology | Drug Combinations | Induced Pluripotent Stem Cells - metabolism | Recoverin - metabolism | Index Medicus
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