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Nature Cell Biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36949 - e36949
Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1 beta-driven neuroinflammation in the pathogenesis of diabetic... 
ADHESION MOLECULE-1 | PROTEIN-KINASE-C | MICROGLIAL ACTIVATION | ENDOTHELIAL-CELLS | BIOLOGY | GENE-EXPRESSION | RETINOPATHY | INDUCTION | INTERLEUKIN-1 INDUCES INTERLEUKIN-1 | MULLER CELLS | BRAIN | Microglia - metabolism | Up-Regulation | Retina - metabolism | Rats, Wistar | Diabetes Mellitus, Experimental - genetics | Male | Interleukin-1beta - genetics | Glial Fibrillary Acidic Protein - metabolism | Hyperglycemia - genetics | Glucose - administration & dosage | Interleukin-1beta - metabolism | Protein Kinase C - metabolism | Diabetes Mellitus, Experimental - metabolism | Interleukin-1beta - antagonists & inhibitors | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rats | Protein Kinase C - antagonists & inhibitors | Random Allocation | Rats, Sprague-Dawley | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Hyperglycemia - metabolism | alpha-Macroglobulins - metabolism | Animals | Endothelium - metabolism | Ceruloplasmin - metabolism | Glucose - metabolism | Neuroglia - metabolism | Astrocytes - metabolism | Ceruloplasmin | Diabetic retinopathy | Protein kinase C | Retinopathy | Pathogenesis | Streptozocin | Retina | Immunoblotting | Glucose | Hyperglycemia | Ischemia | Rodents | Enzyme-linked immunosorbent assay | Enzymes | Cytokines | Astrocytes | Abnormalities | Diabetes mellitus | Blood vessels | Inflammation | IL-1β | Endothelial cells | Endothelium | Microglia | Polymerase chain reaction | Brain research | Diabetes | Glia | Laboratory animals | Subcultures | Apoptosis | Index Medicus
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2011, Volume 20, Issue 1, pp. 33 - 46
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2007, Volume 104, Issue 9, pp. 3225 - 3230
Delta-like 4 (Dll4) is a transmembrane ligand for Notch receptors that is expressed in arterial blood vessels and sprouting endothelial cells. Here we show... 
Sprouting | Sprouts | Blood vessels | Plexus | Lectins | Retina | Pseudopodia | Hindbrain | Embryos | Endothelial cells | Guidance | Angiogenesis | Vascular development | VEGF | angiogenesis | MULTIDISCIPLINARY SCIENCES | MOUSE | MICE LACKING | sprouting | vascular development | LETHALITY | guidance | PATHWAY | NETWORK FORMATION | EMBRYONIC VASCULAR DEVELOPMENT | GROWTH-FACTOR | ARTERIAL-VENOUS DIFFERENTIATION | EXPRESSION | Immunohistochemistry | Retinal Vessels - metabolism | gamma-Aminobutyric Acid - pharmacology | Endothelium, Vascular - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | Retinal Vessels - drug effects | Vascular Endothelial Growth Factor A - metabolism | Animals | In Situ Hybridization | Receptors, Vascular Endothelial Growth Factor - metabolism | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Mice, Mutant Strains | Signal Transduction - physiology | Membrane Proteins - metabolism | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Triglycerides - pharmacology | gamma-Aminobutyric Acid - analogs & derivatives | Retinal Vessels - embryology | Endothelium, Vascular - embryology | Research | Neovascularization | Structure | Vascular endothelial growth factor | Ligands (Biochemistry) | Proteins | Molecules | Cells | Index Medicus | Biological Sciences
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2015, Volume 35, Issue 2, pp. 409 - 420
OBJECTIVE—Vascular smooth muscle cells (VSMC) are important for contraction, blood flow distribution, and regulation of blood vessel diameter, but to what... 
blood-brain barrier | smooth muscle | aneurysm | fibrin | Notch3 | SUBCORTICAL INFARCTS | BRAIN-BARRIER | LEUKOENCEPHALOPATHY | CADASIL | VASCULAR INTEGRITY | DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | AUTOSOMAL-DOMINANT ARTERIOPATHY | HEMATOLOGY | ISCHEMIC-STROKE | EXPRESSION | Capillary Permeability | Muscle, Smooth, Vascular - metabolism | Receptors, Notch - metabolism | Blood Vessels - metabolism | Actins - metabolism | Microvessels - metabolism | Myocytes, Smooth Muscle - pathology | Microvessels - pathology | Male | Receptors, Notch - genetics | Gene Expression Profiling | Actins - genetics | Retinal Vessels - pathology | Gene Expression Regulation, Developmental | Female | Transcription, Genetic | Receptors, Notch - deficiency | Myocytes, Smooth Muscle - metabolism | Biomarkers - metabolism | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Pericytes - metabolism | Genotype | Blood-Brain Barrier - metabolism | Mice, Knockout | Blood-Brain Barrier - pathology | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Receptor, Notch3 | Apoptosis | Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Hematology | Hematologi | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 19, pp. 4025 - 4033
Sprouting of developing blood vessels is mediated by specialized motile endothelial cells localized at the tips of growing capillaries. Following behind the... 
VASCULAR DEVELOPMENT | ANGIOGENIC FACTOR | FACTOR-BETA | BASEMENT-MEMBRANE FORMATION | IN-VIVO | NETWORK FORMATION | UROKINASE RECEPTOR | APELIN | DEFICIENT MICE | HEMATOLOGY | INHIBITS TUMOR-GROWTH | Multigene Family | Oligonucleotide Array Sequence Analysis | Receptors, G-Protein-Coupled - metabolism | TOR Serine-Threonine Kinases - metabolism | Extracellular Matrix - metabolism | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Membrane Proteins - deficiency | Retinal Vessels - cytology | Membrane Proteins - metabolism | Capillaries - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Vascular Endothelial Growth Factor A - pharmacology | Apelin | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Intercellular Signaling Peptides and Proteins | Mice, Inbred C57BL | Zebrafish | Adipokines | Capillaries - growth & development | Haploinsufficiency | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Receptors, G-Protein-Coupled - deficiency | Capillaries - cytology | Endothelial Cells - cytology | Retinal Vessels - growth & development | Apelin Receptors | Mice | Receptors, G-Protein-Coupled - genetics | Endothelial Cells - drug effects | Index Medicus | Abridged Index Medicus | Vascular Biology
Journal Article
Journal Article
Development (Cambridge), ISSN 0950-1991, 2017, Volume 144, Issue 13, pp. 2504 - 2516
Journal Article
Blood, ISSN 0006-4971, 06/2012, Volume 119, Issue 25, pp. 6162 - 6171
Journal Article