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Nature Genetics, ISSN 1061-4036, 09/2009, Volume 41, Issue 9, pp. 1027 - 1031
The primary cilium is an antenna-like structure that protrudes from the cell surface of quiescent/differentiated cells and participates in extracellular signal... 
NETWORK | INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE | POLYCYSTIC KIDNEY-DISEASE | BIOLOGY | GENETICS & HEREDITY | DISORDERS | PROTEINS | FIBROBLASTS | Humans | Fluorescent Dyes - metabolism | Culture Media, Serum-Free | Male | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblasts - ultrastructure | Obesity - genetics | Embryo, Mammalian - metabolism | Intellectual Disability - genetics | Indoles - metabolism | Tubulin - metabolism | Cell Nucleus - metabolism | Transfection | Mice, Mutant Strains | Cilia - ultrastructure | Bardet-Biedl Syndrome - genetics | Chromones - pharmacology | Microsatellite Repeats | Fibroblasts - metabolism | Genetic Linkage | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Cilia - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Fluorescent Antibody Technique, Direct | Retinal Degeneration - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Mice, Transgenic | Genetic Markers | Cilia - metabolism | Cilia - genetics | Pigment Epithelium of Eye - metabolism | Animals | Embryo, Mammalian - cytology | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Polymorphism, Single Nucleotide | Mutation | Pigment Epithelium of Eye - cytology | Penis - abnormalities | Gene mutations | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Brain diseases | Proteins | Tissue | Scanning electron microscopy | Transmission electron microscopy | Cysts | Rodents | Cell division | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2016, Volume 22, Issue 4, pp. 439 - 445
Journal Article
Circulation Research, ISSN 0009-7330, 10/2009, Volume 105, Issue 9, pp. 897 - 905
RATIONALE:Insulin-like growth factor binding protein (IGFBP)-3 modulates vascular development by regulating endothelial progenitor cell (EPC) behavior,... 
Insulin-like growth factor binding protein-3 | Vascular repair | Nitric oxide | Hematopoietic stem cells | nitric oxide | STEM-CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | RAT RETINA | LOW-DENSITY-LIPOPROTEIN | RECEPTOR | ENDOTHELIAL-CELL APOPTOSIS | FACTOR-I | CHOROIDAL NEOVASCULARIZATION | vascular repair | SPHINGOSINE 1-PHOSPHATE | RETINOPATHY | PERIPHERAL VASCULAR DISEASE | hematopoietic stem cells | HEMATOLOGY | insulin-like growth factor binding protein-3 | Cell Proliferation | Mesenteric Arteries - physiopathology | Humans | Male | Green Fluorescent Proteins - genetics | Retinal Neovascularization - metabolism | Retinopathy of Prematurity - physiopathology | Vasodilation | Retinal Vessels - pathology | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Infant, Newborn | Cytoprotection | Disease Models, Animal | Animals, Newborn | Gene Transfer Techniques | Sphingomyelins - metabolism | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Rats | Mice, Transgenic | Mesenteric Arteries - metabolism | Cell Adhesion Molecules - metabolism | Rats, Sprague-Dawley | Cerebral Arteries - metabolism | Stem Cells - pathology | Mice | Retinopathy of Prematurity - metabolism | Endothelial Cells - pathology | Retinal Neovascularization - physiopathology | Retinal Neovascularization - pathology | Astrocytes - metabolism | Cell Movement | Insulin-Like Growth Factor Binding Protein 3 - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphoproteins - metabolism | Stem Cells - metabolism | Cell Death | Female | Microfilament Proteins - metabolism | Nitric Oxide Synthase Type III - metabolism | Ceramides - metabolism | Mice, Inbred C57BL | Cells, Cultured | Cerebral Arteries - physiopathology | Pregnancy | Animals | Retinal Vessels - physiopathology | Scavenger Receptors, Class B - metabolism | Nitric Oxide - metabolism | Retinopathy of Prematurity - pathology | Index Medicus | Vascular Repair | Hematopoietic Stem Cells
Journal Article
Genes and Development, ISSN 0890-9369, 08/2003, Volume 17, Issue 15, pp. 1835 - 1840
Several platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) family members display C-terminal protein motifs that confer... 
Pericyte | Cell retention | Retina | Mesangial cell | PDGF | Heparan sulphate proteoglycan | DIABETIC-RETINOPATHY | VEGF ISOFORMS | pericyte | ANGIOGENESIS | A-CHAIN | DEVELOPMENTAL BIOLOGY | mesangial cell | CELL BIOLOGY | cell retention | retina | IN-VIVO | GENETICS & HEREDITY | MICE | heparan sulphate proteoglycan | HEPARAN-SULFATE PROTEOGLYCANS | GROWTH-FACTOR | BINDING | SMOOTH-MUSCLE CELLS | Kidney - physiology | Vascular Endothelial Growth Factor A | Endothelial Growth Factors - metabolism | Microcirculation - metabolism | Retina - metabolism | Vascular Endothelial Growth Factors | Glomerulosclerosis, Focal Segmental - genetics | Molecular Sequence Data | Intercellular Signaling Peptides and Proteins - metabolism | Lymphokines - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Proto-Oncogene Proteins c-sis - genetics | Proto-Oncogene Proteins c-sis - metabolism | Retinal Degeneration - genetics | Pericytes - metabolism | Proteinuria - genetics | Amino Acid Motifs | Retina - physiology | Phenotype | Platelet-Derived Growth Factor - metabolism | Animals | Endothelium, Vascular - metabolism | Alleles | Mice | Models, Genetic | Mutation | Microscopy, Fluorescence | Cell Movement | Proteins | Blood platelets | Secretion | Analysis | Genetic research | Genetic aspects | Growth factors | Endothelium | Index Medicus | Research Communications | Glomerulosclerosis; Focal Segmental/genetics | Intercellular Signaling Peptides and Proteins/metabolism | Platelet-Derived Growth Factor/metabolism | Proto-Oncogene Proteins c-sis/genetics/metabolism | Proteinuria/genetics | Models; Genetic | Microcirculation/metabolism | Lymphokines/metabolism | Microscopy; Fluorescence | Pericytes/metabolism | Kidney/physiology | Protein Structure; Tertiary | Retinal Degeneration/genetics | Endothelial Growth Factors/metabolism | Endothelium; Vascular/metabolism | Retina/metabolism/physiology
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0132977 - e0132977
Cancer stem cells are cancer cells characterized by stem cell properties and represent a small population of tumor cells that drives tumor development,... 
TESTIS ANTIGEN BORIS | HEPATOCELLULAR-CARCINOMA | SIDE POPULATION | IN-VITRO | INDUCED APOPTOSIS | TELOMERASE | MULTIDISCIPLINARY SCIENCES | IMPRINTED SITES | CTCF | IDENTIFICATION | TUMOR-INITIATING CELLS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | RNA, Small Interfering - genetics | Cell Proliferation | Epithelial Cells - metabolism | Polycomb Repressive Complex 1 - metabolism | Homeodomain Proteins - metabolism | Humans | Retinal Dehydrogenase - metabolism | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Epithelial-Mesenchymal Transition - genetics | Neoplasm Proteins - metabolism | SOXB1 Transcription Factors - metabolism | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | Polycomb Repressive Complex 1 - genetics | Telomerase - genetics | ATP-Binding Cassette Transporters - genetics | Neoplastic Stem Cells - metabolism | SOXB1 Transcription Factors - genetics | Isoenzymes - metabolism | Hyaluronan Receptors - metabolism | ATP-Binding Cassette Transporters - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Telomerase - metabolism | Neoplasm Proteins - genetics | DNA-Binding Proteins - antagonists & inhibitors | Nanog Homeobox Protein | Signal Transduction | Isoenzymes - genetics | Spheroids, Cellular - metabolism | Epithelial Cells - pathology | Retinal Dehydrogenase - genetics | DNA-Binding Proteins - genetics | Organ Specificity | Hyaluronan Receptors - genetics | Homeodomain Proteins - genetics | Phenotype | Octamer Transcription Factor-3 - metabolism | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cell Movement | RNA, Small Interfering - metabolism | RNA | Genes | Colorectal cancer | Stem cells | Genetic aspects | Gene expression | Cancer | Protein binding | Neurosciences | Germ cells | Telomerase reverse transcriptase | Populations | Dyes | Mesenchyme | Oct-4 protein | Gene regulation | Oncology | Spheres | Drug resistance | Tissues | Metastases | DNA-binding protein | CD44 antigen | Cell cycle | Life sciences | Colon | Telomerase | Growth factors | Deoxyribonucleic acid--DNA | Medical research | Antigens | Cell survival | Tumor cells | Invasiveness | Cervix | Survival | Brain research | Molecular modelling | Medical prognosis | Epigenetics | Breast | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2017, Volume 58, Issue 12, pp. 5043 - 5055
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15579 - 15584
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 08/2007, Volume 293, Issue 2, pp. 641 - 649
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 02/2013, Volume 131, Issue 2, pp. 160 - 165
OBJECTIVE To evaluate the association between vitreous fluid levels of inflammatory factors and macular edema in patients with branch retinal vein occlusion... 
C-REACTIVE PROTEIN | EPITHELIUM-DERIVED FACTOR | SIGNALING PATHWAYS | ACUTE MYOCARDIAL-INFARCTION | OPHTHALMOLOGY | SMOOTH-MUSCLE-CELLS | NF-KAPPA-B | ADHESION MOLECULE-1 ICAM-1 | TRANSCRIPTION FACTOR | ENDOTHELIAL GROWTH-FACTOR | LONG PENTRAXIN PTX3 | Capillary Permeability | Humans | Male | Nerve Growth Factors - metabolism | Vascular Endothelial Growth Factor A - metabolism | Case-Control Studies | C-Reactive Protein - metabolism | Vitreous Body - metabolism | Inflammation Mediators - metabolism | Retinal Vein Occlusion - surgery | Female | Vitrectomy | Chemokine CCL2 - metabolism | Retrospective Studies | Interleukin-6 - metabolism | Fluorescein Angiography | Biomarkers - metabolism | Enzyme-Linked Immunosorbent Assay | Serpins - metabolism | Tomography, Optical Coherence | Retinal Vein - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Macular Edema - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Eye Proteins - metabolism | Macular Edema - surgery | Aged | Serum Amyloid P-Component - metabolism | Retinal Vein Occlusion - metabolism | Complications and side effects | Usage | Eye diseases | Research | Diagnosis | Retinal diseases | Vascular endothelial growth factor | Coherence (Optics) | Risk factors | Enzyme-linked immunosorbent assay | Index Medicus | Abridged Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 04/2018, Volume 67, Issue 4, pp. 769 - 781
Tight junctions (TJs) involve close apposition of transmembrane proteins between cells. Although TJ proteins have been studied in detail, the role of lipids is... 
STARGARDT-3 MACULAR DYSTROPHY | NEONATAL LETHALITY | ELOVL4 PROTEIN | ENDOCRINOLOGY & METABOLISM | BARRIER FUNCTION | RETINOPATHY | FATTY-ACIDS | ENDOTHELIAL-CELL PERMEABILITY | TANDEM MASS-SPECTROMETRY | OCCLUDIN PHOSPHORYLATION | EXPRESSION | Retina - metabolism | Humans | Claudin-5 - metabolism | Retinal Vessels - ultrastructure | Vascular Endothelial Growth Factor A - metabolism | Capillary Permeability - genetics | Occludin - metabolism | Endothelial Cells - ultrastructure | Cattle | Interleukin-1beta - metabolism | Diabetes Mellitus, Experimental - complications | Membrane Proteins - metabolism | Diabetic Retinopathy - etiology | Eye Proteins - genetics | Zonula Occludens-1 Protein - metabolism | Diabetes Mellitus, Experimental - metabolism | Tight Junctions - metabolism | Ceramides - metabolism | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Membrane Proteins - genetics | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Blood-Retinal Barrier - metabolism | Tight Junctions - ultrastructure | Animals | Eye Proteins - metabolism | Mice | Complications and side effects | Diabetic retinopathy | Diabetes | Research | Gene expression | Vascular endothelial growth factor | Risk factors | Retinopathy | Cytokines | Tight junctions | Diabetes mellitus | Lipids | Retina | Permeability | Fatty acids | Zonula occludens-1 protein | Membrane proteins | Proteins | Apposition | Ultrastructure | Index Medicus | Abridged Index Medicus | Complications | 0107
Journal Article
Investigative ophthalmology & visual science, ISSN 0146-0404, 2012, Volume 53, Issue 6, pp. 2968 - 2977
PURPOSE. Retinopathy of prematurity (ROP) is a leading cause of blindness in children and is, in its most severe form, characterized by uncontrolled growth of... 
RETINAL NEOVASCULARIZATION | BLOCKERS | MOUSE MODEL | RAT RETINA | OPHTHALMOLOGY | INFANTILE HEMANGIOMAS | FACTOR EXPRESSION | PREMATURITY | INFANCY | ENDOTHELIAL GROWTH-FACTOR | Up-Regulation | Cell Proliferation | Angiopoietin-2 - genetics | Humans | Gene Expression Profiling | Retinal Neovascularization - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiopoietin-2 - metabolism | Dose-Response Relationship, Drug | Receptors, Vascular Endothelial Growth Factor - metabolism | Retina - cytology | Propranolol - administration & dosage | Injections, Subcutaneous | Retinal Neovascularization - prevention & control | Erythropoietin - metabolism | Receptors, Vascular Endothelial Growth Factor - genetics | Drug Evaluation, Preclinical | Receptors, Adrenergic, beta - metabolism | Adrenergic beta-Antagonists - administration & dosage | Infant, Newborn | Disease Models, Animal | RNA - metabolism | Animals, Newborn | Oxygen - toxicity | Enzyme-Linked Immunosorbent Assay | Administration, Oral | Injections, Intraperitoneal | Reverse Transcriptase Polymerase Chain Reaction | Angiopoietin-1 - genetics | Erythropoietin - genetics | Animals | Retinopathy of Prematurity - prevention & control | Mice | Retinopathy of Prematurity - metabolism | In Vitro Techniques | Endothelial Cells - drug effects | Index Medicus | Disease Models | Other Medical Sciences | Endothelial Cells/drug effects | Oxygen/toxicity | Drug Evaluation | Vascular Endothelial Growth Factor A/genetics/metabolism | Infant | Propranolol/administration & dosage | Adrenergic | Oral | Intraperitoneal | RNA/metabolism | Receptors | Retinopathy of Prematurity/metabolism/prevention & control | beta/metabolism | Preclinical | Adrenergic beta-Antagonists/administration & dosage | Drug | Administration | Retinal Neovascularization/metabolism/prevention & control | Subcutaneous | Angiopoietin-2/genetics/metabolism | Erythropoietin/genetics/metabolism | Retina/cytology | Angiopoietin-1/genetics/metabolism | Injections | Newborn | Annan medicin och hälsovetenskap | Animal | Dose-Response Relationship | Vascular Endothelial Growth Factor/genetics/metabolism
Journal Article