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2008, 1st ed., Progress in brain research, ISBN 9780444532565, Volume 173., xvi, 622 p., [16] p. of plates
Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss... 
Glaucoma | Treatment
Book
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1433 - 1445
Oxidative stress contributes to the loss of neurons in many disease conditions as well as during normal aging; however, small-molecule agents that reduce... 
RETINAL DEGENERATION | MEDICINE, RESEARCH & EXPERIMENTAL | DIFFUSIBLE FACTOR | OXIDATIVE STRESS | OPTIC-NERVE | PLACEBO-CONTROLLED PHASE-3 | MOUSE MODEL | AXON REGENERATION | PARTIAL RECOVERY | RETINITIS-PIGMENTOSA | CONE CELL-DEATH | NF-E2-Related Factor 2 - physiology | Dependovirus - genetics | Genetic Therapy | Catalase - therapeutic use | NF-E2-Related Factor 2 - therapeutic use | Oxidative Stress - physiology | Genetic Vectors - therapeutic use | Mice, Mutant Strains | Superoxide Dismutase - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Neurons - physiology | NF-E2-Related Factor 2 - genetics | Optic Nerve Injuries - therapy | Transcription Factors - therapeutic use | Retinal Ganglion Cells - physiology | Transcription Factors - physiology | Catalase - physiology | Mice, Inbred C57BL | Optic Nerve Injuries - physiopathology | Nerve Crush | Retinal Cone Photoreceptor Cells - physiology | Genetic Vectors - genetics | Superoxide Dismutase - therapeutic use | Animals | Retinitis Pigmentosa - therapy | Mice | Nerve Degeneration | Apoptosis | Oxidative stress | Transcription factors | Nervous system | Development and progression | Degeneration | Genetic aspects | Health aspects | Antioxidants | Proteins | Enzymes | Statistical analysis | Optic nerve | Disease | Genes | Lipids | Photoreceptors | Physiology | Index Medicus | Abridged Index Medicus | Genetics | Neuroscience | Ophthalmology | Therapeutics
Journal Article
Current Alzheimer Research, ISSN 1567-2050, 01/2010, Volume 7, Issue 1, pp. 3 - 14
Journal Article
Investigative ophthalmology & visual science, ISSN 0146-0404, 2012, Volume 53, Issue 6, pp. 2715 - 2719
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2018, Volume 59, Issue 8, pp. 1414 - 1423
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2016, Volume 113, Issue 19, pp. E2655 - E2664
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 9, pp. e104416 - e104416
Glaucoma is a progressive optic nerve degenerative disease that often leads to blindness. Local inflammatory responses are implicated in the pathology of... 
Microglia - metabolism | Optic Disk - physiopathology | Intraocular Pressure - drug effects | Mouth - drug effects | Humans | Lipopolysaccharides - administration & dosage | Microbiota - drug effects | Nerve Degeneration - physiopathology | African Americans | Male | Complement System Proteins - metabolism | Brain - metabolism | Microglia - pathology | Complement System Proteins - genetics | Female | Mice, Inbred DBA | Glaucoma - physiopathology | Glaucoma - microbiology | Microglia - drug effects | Mice, Inbred C57BL | Nerve Degeneration - microbiology | Glaucoma - complications | Nerve Degeneration - complications | Toll-Like Receptor 4 - metabolism | Nerve Degeneration - pathology | Brain - drug effects | Up-Regulation - drug effects | Animals | Mouth - microbiology | Lipopolysaccharides - pharmacology | Mouth - pathology | Glaucoma - pathology | Optic Disk - drug effects | Optic Disk - pathology | Infection | Glaucoma | Analysis | Blindness | Inflammation | Gene expression | Health aspects | Pediatrics | Animal models | Central nervous system | Retina | Biology | Infections | Activation | Complement | Dosage | Lipopolysaccharides | Signal transduction | Neurodegeneration | Rodents | Toll-like receptors | Bacteria | Degeneration | Discriminant analysis | Optic nerve | Bacterial infections | Neurodegenerative diseases | Pharmacology | TLR4 protein | Preventive medicine | Dentistry | Patients | Microglia | Pathology | Signaling | Naloxone | Alzheimers disease | Dementia | Animal cognition | Index Medicus
Journal Article
Journal Article
American Journal of Pathology, ISSN 0002-9440, 10/2006, Volume 169, Issue 4, pp. 1353 - 1364
Journal Article
Diabetes, ISSN 0012-1797, 07/2013, Volume 62, Issue 7, pp. 2569 - 2578
Journal Article