Retina, ISSN 0275-004X, 09/2013, Volume 33, Issue 8, pp. 1659 - 1672
Purpose: To report nine cases of pachychoroid pigment epitheliopathy. Methods: An observational case series of nine patients who underwent comprehensive...
forme | fruste | chorioretinopathy | central | choroidal | thickening | serous | INDOCYANINE GREEN VIDEOANGIOGRAPHY | PHOTODYNAMIC THERAPY | OPTICAL COHERENCE TOMOGRAPHY | FUNDUS AUTOFLUORESCENCE | MACULAR DEGENERATION | FOLLOW-UP | CENTRAL SEROUS CHORIORETINOPATHY | ANGIOGRAPHIC FINDINGS | VASCULAR HYPERPERMEABILITY | OPHTHALMOLOGY | POLYPOIDAL CHOROIDAL VASCULOPATHY | Polyps - diagnosis | Tomography, Optical Coherence | Humans | Middle Aged | Choroid - blood supply | Male | Visual Acuity | Retinal Pigment Epithelium - pathology | Central Serous Chorioretinopathy - diagnosis | Aged, 80 and over | Adult | Female | Aged | Choroid - pathology | Fluorescein Angiography
forme | fruste | chorioretinopathy | central | choroidal | thickening | serous | INDOCYANINE GREEN VIDEOANGIOGRAPHY | PHOTODYNAMIC THERAPY | OPTICAL COHERENCE TOMOGRAPHY | FUNDUS AUTOFLUORESCENCE | MACULAR DEGENERATION | FOLLOW-UP | CENTRAL SEROUS CHORIORETINOPATHY | ANGIOGRAPHIC FINDINGS | VASCULAR HYPERPERMEABILITY | OPHTHALMOLOGY | POLYPOIDAL CHOROIDAL VASCULOPATHY | Polyps - diagnosis | Tomography, Optical Coherence | Humans | Middle Aged | Choroid - blood supply | Male | Visual Acuity | Retinal Pigment Epithelium - pathology | Central Serous Chorioretinopathy - diagnosis | Aged, 80 and over | Adult | Female | Aged | Choroid - pathology | Fluorescein Angiography
Journal Article
Vision Research, ISSN 0042-6989, 2008, Volume 48, Issue 20, pp. 2022 - 2041
The visual pigments of vertebrates evolved about 500 million years ago, before the major evolutionary step of the development of jaws. Four spectrally distinct...
Evolution | Opsin | Visual pigment | Cone | Rod | LUNGFISH NEOCERATODUS-FORSTERI | visual pigment | rod | opsin | TRICHROMATIC COLOR-VISION | evolution | TUNING SPECTRAL SENSITIVITY | cone | MANATEE TRICHECHUS-MANATUS | NEUROSCIENCES | BEARING AMINO-ACIDS | PSYCHOLOGY | AFRICAN CICHLID FISHES | LAKE MALAWI CICHLIDS | OPSIN GENE DUPLICATION | OPHTHALMOLOGY | COELACANTH LATIMERIA-CHALUMNAE | NEW-WORLD MONKEYS | Biological Evolution | Animals | Opsins - genetics | Vertebrates - genetics | Retinal Pigments - genetics | Retinal Rod Photoreceptor Cells - physiology | Retinal Cone Photoreceptor Cells - physiology | Vertebrates - physiology | Color Perception - genetics | Evolutionary biology | Visual pigments | Dyes and dyeing
Evolution | Opsin | Visual pigment | Cone | Rod | LUNGFISH NEOCERATODUS-FORSTERI | visual pigment | rod | opsin | TRICHROMATIC COLOR-VISION | evolution | TUNING SPECTRAL SENSITIVITY | cone | MANATEE TRICHECHUS-MANATUS | NEUROSCIENCES | BEARING AMINO-ACIDS | PSYCHOLOGY | AFRICAN CICHLID FISHES | LAKE MALAWI CICHLIDS | OPSIN GENE DUPLICATION | OPHTHALMOLOGY | COELACANTH LATIMERIA-CHALUMNAE | NEW-WORLD MONKEYS | Biological Evolution | Animals | Opsins - genetics | Vertebrates - genetics | Retinal Pigments - genetics | Retinal Rod Photoreceptor Cells - physiology | Retinal Cone Photoreceptor Cells - physiology | Vertebrates - physiology | Color Perception - genetics | Evolutionary biology | Visual pigments | Dyes and dyeing
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 05/2014, Volume 1837, Issue 5, pp. 664 - 673
Cone visual pigments are visual opsins that are present in vertebrate cone photoreceptor cells and act as photoreceptor molecules responsible for photopic...
Molecular evolution | Retina | Rhodopsin | Color vision | G-protein coupled receptors | Opsin family | RHODOPSIN ACTIVATION | GREEN COLOR-VISION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESONANCE RAMAN MICROPROBE | RETINAL SCHIFF-BASE | LOW-TEMPERATURE | ROD PHOTORECEPTOR CELLS | BIOPHYSICS | PROTEIN-COUPLED RECEPTOR | WAVELENGTH REGULATION | MOLECULAR-PROPERTIES | METARHODOPSIN-II | Opsins - classification | Humans | Molecular Conformation | Retinal Cone Photoreceptor Cells - physiology | Models, Molecular | Retinaldehyde - chemistry | Phylogeny | Retinaldehyde - metabolism | Rhodopsin - metabolism | Retinal Cone Photoreceptor Cells - ultrastructure | Animals | Opsins - chemistry | Color Vision - physiology | Retinal Cone Photoreceptor Cells - chemistry | Opsins - metabolism | Evolution, Molecular | Rhodopsin - chemistry | Proteins | G proteins | Isomerization | Analysis
Molecular evolution | Retina | Rhodopsin | Color vision | G-protein coupled receptors | Opsin family | RHODOPSIN ACTIVATION | GREEN COLOR-VISION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESONANCE RAMAN MICROPROBE | RETINAL SCHIFF-BASE | LOW-TEMPERATURE | ROD PHOTORECEPTOR CELLS | BIOPHYSICS | PROTEIN-COUPLED RECEPTOR | WAVELENGTH REGULATION | MOLECULAR-PROPERTIES | METARHODOPSIN-II | Opsins - classification | Humans | Molecular Conformation | Retinal Cone Photoreceptor Cells - physiology | Models, Molecular | Retinaldehyde - chemistry | Phylogeny | Retinaldehyde - metabolism | Rhodopsin - metabolism | Retinal Cone Photoreceptor Cells - ultrastructure | Animals | Opsins - chemistry | Color Vision - physiology | Retinal Cone Photoreceptor Cells - chemistry | Opsins - metabolism | Evolution, Molecular | Rhodopsin - chemistry | Proteins | G proteins | Isomerization | Analysis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2009, Volume 284, Issue 44, pp. 30177 - 30186
Wet age-related macular degeneration (AMD) attacks the integrity of the retinal pigment epithelium (RPE) barrier system. The pathogenic process was...
DIABETIC-RETINOPATHY | CELLS | OXIDATIVE STRESS | FACTOR PEDF | AMYLOID-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | A-BETA | FAMILIAL ALZHEIMERS-DISEASE | MACULAR DEGENERATION | CHOROIDAL NEOVASCULARIZATION | FACTOR VEGF EXPRESSION | Macular Degeneration - etiology | Retinal Pigment Epithelium - metabolism | Vascular Endothelial Growth Factor A | Signal Transduction | Vascular Endothelial Growth Factor Receptor-2 - analysis | Humans | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Permeability | Serpins - physiology | Amyloid Precursor Protein Secretases - metabolism | Animals | Swine | Retinal Pigment Epithelium - physiology | Eye Proteins - physiology | Nerve Growth Factors - physiology | Macular Degeneration - pathology | Molecular Basis of Cell and Developmental Biology
DIABETIC-RETINOPATHY | CELLS | OXIDATIVE STRESS | FACTOR PEDF | AMYLOID-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | A-BETA | FAMILIAL ALZHEIMERS-DISEASE | MACULAR DEGENERATION | CHOROIDAL NEOVASCULARIZATION | FACTOR VEGF EXPRESSION | Macular Degeneration - etiology | Retinal Pigment Epithelium - metabolism | Vascular Endothelial Growth Factor A | Signal Transduction | Vascular Endothelial Growth Factor Receptor-2 - analysis | Humans | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Permeability | Serpins - physiology | Amyloid Precursor Protein Secretases - metabolism | Animals | Swine | Retinal Pigment Epithelium - physiology | Eye Proteins - physiology | Nerve Growth Factors - physiology | Macular Degeneration - pathology | Molecular Basis of Cell and Developmental Biology
Journal Article
Retina, ISSN 0275-004X, 2014, Volume 34, Issue 6, pp. 1156 - 1162
Purpose: To evaluate the prevalence of retinal pigment epithelium (RPE) tears associated with anti-VEGF therapy and its relation with retinal pigment...
Macular degeneration | Retinal pigment epithelium tears | Retinal pigment epithelial detachment | Vascular endothelial growth factor | Ranibizumab | Bevacizumab | RANIBIZUMAB THERAPY | OPTICAL COHERENCE TOMOGRAPHY | SECONDARY | INTRAVITREAL BEVACIZUMAB INJECTION | RISK | RPE TEARS | CHOROIDAL NEOVASCULARIZATION | ranibizumab | macular degeneration | vascular endothelial growth factor | retinal pigment epithelium tears | bevacizumab | AMD | OPHTHALMOLOGY | retinal pigment epithelial detachment | Antibodies, Monoclonal, Humanized - adverse effects | Retinal Perforations - chemically induced | Retinal Perforations - epidemiology | Macular Degeneration - physiopathology | Humans | Male | Retinal Detachment - drug therapy | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Visual Acuity | Macular Degeneration - drug therapy | Incidence | Retinal Pigment Epithelium | Analysis of Variance | Turkey - epidemiology | Aged, 80 and over | Female | Aged | Retrospective Studies | Angiogenesis Inhibitors - adverse effects
Macular degeneration | Retinal pigment epithelium tears | Retinal pigment epithelial detachment | Vascular endothelial growth factor | Ranibizumab | Bevacizumab | RANIBIZUMAB THERAPY | OPTICAL COHERENCE TOMOGRAPHY | SECONDARY | INTRAVITREAL BEVACIZUMAB INJECTION | RISK | RPE TEARS | CHOROIDAL NEOVASCULARIZATION | ranibizumab | macular degeneration | vascular endothelial growth factor | retinal pigment epithelium tears | bevacizumab | AMD | OPHTHALMOLOGY | retinal pigment epithelial detachment | Antibodies, Monoclonal, Humanized - adverse effects | Retinal Perforations - chemically induced | Retinal Perforations - epidemiology | Macular Degeneration - physiopathology | Humans | Male | Retinal Detachment - drug therapy | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Visual Acuity | Macular Degeneration - drug therapy | Incidence | Retinal Pigment Epithelium | Analysis of Variance | Turkey - epidemiology | Aged, 80 and over | Female | Aged | Retrospective Studies | Angiogenesis Inhibitors - adverse effects
Journal Article
1979, ISBN 9780674766846, x, 521
Book
1995, Medical intelligence unit (Unnumbered), ISBN 1570592551, 141
Book
Retina, ISSN 0275-004X, 2016, Volume 36, Issue 12, pp. S65 - S72
Purpose: To describe retinal pigment epithelium (RPE) aperture and to generate hypotheses about pathogenesis of this previously unreported finding in the...
Indocyanine green angiography | Fluorescein angiography | Fundus autofluorescence | Optical coherence tomography | Tear | Apertures | Retinal pigment epithelium detachment | Rip | Avascular | DRUSEN | fluorescein angiography | optical coherence tomography | MACULAR DEGENERATION | CLASSIFICATION | apertures | PATHOGENESIS | TEARS | indocyanine green angiography | THERAPY | tear | fundus autofluorescence | avascular | rip | OPHTHALMOLOGY | retinal pigment epithelium detachment | GEOGRAPHIC ATROPHY
Indocyanine green angiography | Fluorescein angiography | Fundus autofluorescence | Optical coherence tomography | Tear | Apertures | Retinal pigment epithelium detachment | Rip | Avascular | DRUSEN | fluorescein angiography | optical coherence tomography | MACULAR DEGENERATION | CLASSIFICATION | apertures | PATHOGENESIS | TEARS | indocyanine green angiography | THERAPY | tear | fundus autofluorescence | avascular | rip | OPHTHALMOLOGY | retinal pigment epithelium detachment | GEOGRAPHIC ATROPHY
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2016, Volume 20, Issue 9, pp. 1651 - 1663
Among retinal macular diseases, the juvenile recessive Stargardt disease and the age‐related degenerative disease arise from carbonyl and oxidative stresses...
phloroglucinol | all‐trans‐retinal | retinal pigment epithelium | chromene adduct | bisretinoid A2E | photoreceptor | all-trans-retinal | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE-STRESS | LIPOFUSCIN | MACULAR DEGENERATION | MECHANISMS | CELL BIOLOGY | INDUCED CELL-DAMAGE | IN-VIVO | DISEASE | MICE | ACCUMULATION | BISRETINOIDS | Hydrogen Peroxide - toxicity | Retinal Pigment Epithelium - metabolism | Retinoids - metabolism | Oxidative Stress | Rats, Long-Evans | Benzopyrans - metabolism | Chromatography, High Pressure Liquid | Retinal Pigment Epithelium - pathology | Animals | Proton Magnetic Resonance Spectroscopy | Protective Agents - pharmacology | Retinaldehyde - toxicity | Cytoprotection - drug effects | Phloroglucinol - pharmacology | Cell Death - drug effects | Photoreceptor Cells, Vertebrate - metabolism | Retinal Pigment Epithelium - drug effects | Chemical inhibitors | Peroxides | Epithelium | Analysis | Retina | Photoreceptors | Toxicity | Apoptosis | Cell culture | Oxidative stress | Phosphatidylethanolamine | Reactive oxygen species | Transformation | Hydrogen peroxide | Medical treatment | Phloroglucinol | Lipid peroxidation | Lipids | Phenolic compounds | Accumulation | Retinal pigment epithelium | Organic chemistry | Cell death | Phenols | Polyphenols | Carbonyls | Index Medicus | Life Sciences | Human health and pathology | Pharmacology | Sensory Organs | Pharmaceutical sciences | Original
phloroglucinol | all‐trans‐retinal | retinal pigment epithelium | chromene adduct | bisretinoid A2E | photoreceptor | all-trans-retinal | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE-STRESS | LIPOFUSCIN | MACULAR DEGENERATION | MECHANISMS | CELL BIOLOGY | INDUCED CELL-DAMAGE | IN-VIVO | DISEASE | MICE | ACCUMULATION | BISRETINOIDS | Hydrogen Peroxide - toxicity | Retinal Pigment Epithelium - metabolism | Retinoids - metabolism | Oxidative Stress | Rats, Long-Evans | Benzopyrans - metabolism | Chromatography, High Pressure Liquid | Retinal Pigment Epithelium - pathology | Animals | Proton Magnetic Resonance Spectroscopy | Protective Agents - pharmacology | Retinaldehyde - toxicity | Cytoprotection - drug effects | Phloroglucinol - pharmacology | Cell Death - drug effects | Photoreceptor Cells, Vertebrate - metabolism | Retinal Pigment Epithelium - drug effects | Chemical inhibitors | Peroxides | Epithelium | Analysis | Retina | Photoreceptors | Toxicity | Apoptosis | Cell culture | Oxidative stress | Phosphatidylethanolamine | Reactive oxygen species | Transformation | Hydrogen peroxide | Medical treatment | Phloroglucinol | Lipid peroxidation | Lipids | Phenolic compounds | Accumulation | Retinal pigment epithelium | Organic chemistry | Cell death | Phenols | Polyphenols | Carbonyls | Index Medicus | Life Sciences | Human health and pathology | Pharmacology | Sensory Organs | Pharmaceutical sciences | Original
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 46, Issue 6, pp. 879 - 890
Retinal rod and cone pigments consist of an apoprotein, opsin, covalently linked to a chromophore, 11- retinal. Here we demonstrate that the formation of the...
ROD OUTER SEGMENTS | RETINALDEHYDE-BINDING PROTEIN | RHODOPSIN | DARK-ADAPTATION | VISUAL-PIGMENT | NEUROSCIENCES | SENSITIVITY REGULATION | SALAMANDER RETINA | PHOTOTRANSDUCTION | ACTIVATES TRANSDUCTION | PHOTORECEPTORS | Photobleaching - drug effects | Electrophysiology | Membrane Potentials - radiation effects | Vision, Ocular - drug effects | Retinaldehyde - metabolism | Urodela | Dark Adaptation | Dose-Response Relationship, Drug | Vision, Ocular - physiology | Retina - cytology | Time Factors | Photobleaching - radiation effects | Carrier Proteins - pharmacology | Rod Opsins - metabolism | Membrane Potentials - drug effects | Cells, Cultured | Color | Retinal Cone Photoreceptor Cells - physiology | Spectrophotometry - methods | Membrane Potentials - physiology | Retinal Pigments - physiology | Algorithms | Animals | Larva | Photic Stimulation - methods | Retinaldehyde - pharmacology | Retinal Cone Photoreceptor Cells - drug effects | Dose-Response Relationship, Radiation | Animal pigments | Neurosciences | Amphibians | Dyes and dyeing | Proteins | Cell culture | Light | Chemical bonds | Retina | Photoreceptors | Experiments
ROD OUTER SEGMENTS | RETINALDEHYDE-BINDING PROTEIN | RHODOPSIN | DARK-ADAPTATION | VISUAL-PIGMENT | NEUROSCIENCES | SENSITIVITY REGULATION | SALAMANDER RETINA | PHOTOTRANSDUCTION | ACTIVATES TRANSDUCTION | PHOTORECEPTORS | Photobleaching - drug effects | Electrophysiology | Membrane Potentials - radiation effects | Vision, Ocular - drug effects | Retinaldehyde - metabolism | Urodela | Dark Adaptation | Dose-Response Relationship, Drug | Vision, Ocular - physiology | Retina - cytology | Time Factors | Photobleaching - radiation effects | Carrier Proteins - pharmacology | Rod Opsins - metabolism | Membrane Potentials - drug effects | Cells, Cultured | Color | Retinal Cone Photoreceptor Cells - physiology | Spectrophotometry - methods | Membrane Potentials - physiology | Retinal Pigments - physiology | Algorithms | Animals | Larva | Photic Stimulation - methods | Retinaldehyde - pharmacology | Retinal Cone Photoreceptor Cells - drug effects | Dose-Response Relationship, Radiation | Animal pigments | Neurosciences | Amphibians | Dyes and dyeing | Proteins | Cell culture | Light | Chemical bonds | Retina | Photoreceptors | Experiments
Journal Article
2017, ISBN 3319561316, 166
This illustrated book offers detailed guidance on the differential diagnosis and therapy of detachment of the retinal pigment epithelium (PED), a frequently...
Retinal Detachment | Ophthalmology | Medicine & Public Health | Retinal detachment
Retinal Detachment | Ophthalmology | Medicine & Public Health | Retinal detachment
eBook
Physiological Reviews, ISSN 0031-9333, 07/2005, Volume 85, Issue 3, pp. 845 - 881
Located between vessels of the choriocapillaris and light-sensitive outer segments of the photoreceptors, the retinal pigment epithelium (RPE) closely...
CYCLIC ADENOSINE-MONOPHOSPHATE | PROTEIN-KINASE-C | PHYSIOLOGY | PHOTORECEPTOR OUTER SEGMENTS | INCLUDING FLOW DETERMINATIONS | HUMAN RPE CELLS | LYSOSOMAL DEGRADATIVE FUNCTIONS | VITELLIFORM MACULAR DYSTROPHY | N-RETINYLIDENE ETHANOLAMINE | L-TYPE CHANNELS | ENDOTHELIAL GROWTH-FACTOR | Vision, Ocular - physiology | Animals | Humans | Light | Pigment Epithelium of Eye - embryology | Pigment Epithelium of Eye - physiology | Retinal Degeneration - pathology | Photoreceptor Cells - physiology | Phagocytosis | Photochemistry | Case studies | Physiological aspects | Retinal degeneration | Epithelium | Epithelial cells | Retinal pigment epithelium
CYCLIC ADENOSINE-MONOPHOSPHATE | PROTEIN-KINASE-C | PHYSIOLOGY | PHOTORECEPTOR OUTER SEGMENTS | INCLUDING FLOW DETERMINATIONS | HUMAN RPE CELLS | LYSOSOMAL DEGRADATIVE FUNCTIONS | VITELLIFORM MACULAR DYSTROPHY | N-RETINYLIDENE ETHANOLAMINE | L-TYPE CHANNELS | ENDOTHELIAL GROWTH-FACTOR | Vision, Ocular - physiology | Animals | Humans | Light | Pigment Epithelium of Eye - embryology | Pigment Epithelium of Eye - physiology | Retinal Degeneration - pathology | Photoreceptor Cells - physiology | Phagocytosis | Photochemistry | Case studies | Physiological aspects | Retinal degeneration | Epithelium | Epithelial cells | Retinal pigment epithelium
Journal Article