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1. Full Text Visual Prognosis in USH2A -Associated Retinitis Pigmentosa Is Worse for Patients with Usher Syndrome Type IIa Than for Those with Nonsyndromic Retinitis Pigmentosa
by Pierrache, Laurence H.M., MD|Hartel, Bas P., MD|van Wijk, Erwin, PhD|Meester-Smoor, Magda A., PhD|Cremers, Frans P.M., PhD|de Baere, Elfride, MD, PhD|de Zaeytijd, Julie, MD|van Schooneveld, Mary J., MD, PhD|Cremers, Cor W.R.J., MD, PhD|Dagnelie, Gislin, PhD|Hoyng, Carel B., MD, PhD|Bergen, Arthur A., PhD|Leroy, Bart P., MD, PhD|Pennings, Ronald J.E., MD, PhD|van den Born, L. Ingeborgh, MD, PhD|Klaver, Caroline C.W., MD, PhD
Ophthalmology, ISSN 0161-6420, 2016, Volume 123, Issue 5, pp. 1151 - 1160
Purpose USH2A mutations are an important cause of retinitis pigmentosa (RP) with or without congenital sensorineural hearing impairment. We studied... 
Ophthalmology | Vision, Low - physiopathology | Visual Fields - physiology | Prognosis | Follow-Up Studies | Genetic Association Studies | Blindness - physiopathology | Extracellular Matrix Proteins - genetics | Humans | Middle Aged | Retinitis Pigmentosa - genetics | Male | Usher Syndromes - genetics | DNA Mutational Analysis | Adolescent | Adult | Female | Aged | Mutation | Usher Syndromes - physiopathology | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Medical colleges | Retinitis pigmentosa | Epidemiology | Medical genetics | Index Medicus
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2. Full Text Rates of Decline in Regions of the Visual Field Defined by Frequency-Domain Optical Coherence Tomography in Patients with RPGR -Mediated X-Linked Retinitis Pigmentosa
by Birch, David G., PhD|Locke, Kirsten G., RN|Felius, Joost, PhD|Klein, Martin, MS|Wheaton, Dianna K.H., PhD|Hoffman, Dennis R., PhD|Hood, Donald C., PhD
Ophthalmology, ISSN 0161-6420, 2015, Volume 122, Issue 4, pp. 833 - 839
Purpose To determine whether annual decline in visual field sensitivity is greater in the transition zone at the edge of the frequency-domain optical coherence... 
Ophthalmology | BOUNDARIES | CLINICAL-TRIAL | DOCOSAHEXAENOIC ACID | SENSITIVITY | OPHTHALMOLOGY | RECEPTOR | MULTIFOCAL ELECTRORETINOGRAM | HEALTHY | DISEASED RETINA | THICKNESS | Visual Fields - physiology | Prospective Studies | Follow-Up Studies | Tomography, Optical Coherence | Humans | Retina - physiopathology | Retinitis Pigmentosa - genetics | Male | Genetic Diseases, X-Linked - diagnosis | Retinitis Pigmentosa - diagnosis | Young Adult | Vision Disorders - physiopathology | Sensitivity and Specificity | Adolescent | Adult | Female | Genetic Diseases, X-Linked - genetics | Visual Field Tests | Eye Proteins - genetics | Mutation | Child | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Genetic Diseases, X-Linked - physiopathology | Tomography | Statistics | Index Medicus
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3. Full Text Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
by Punzo, Claudio and Cepko, Constance L and Kornacker, Karl
Nature Neuroscience, ISSN 1097-6256, 01/2009, Volume 12, Issue 1, pp. 44 - 52
Retinitis pigmentosa is an incurable retinal disease that leads to blindness. One puzzling aspect concerns the progression of the disease. Although most... 
RETINAL DEGENERATION | DIFFUSIBLE FACTOR | OXIDATIVE STRESS | RD MOUSE | CHAPERONE-MEDIATED AUTOPHAGY | PHOTORECEPTOR | ROD CGMP-PHOSPHODIESTERASE | NEUROSCIENCES | MICE LACKING | HYPOXIA-INDUCIBLE FACTOR-1 | CELL-DEATH | Retina - metabolism | Retinal Rod Photoreceptor Cells - metabolism | Autophagy | Time Factors | Microarray Analysis | Cell Death | Cyclic Nucleotide Phosphodiesterases, Type 6 - deficiency | Transgenes | Retinitis Pigmentosa - physiopathology | Cell Survival - drug effects | Insulin - pharmacology | Retinal Cone Photoreceptor Cells | Mice, Inbred C57BL | Retinitis Pigmentosa - metabolism | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Rhodopsin - genetics | Animal Nutritional Physiological Phenomena | Rhodopsin - deficiency | Insulin - deficiency | Nutrition Disorders - physiopathology | Mice | TOR Serine-Threonine Kinases | Amino Acid Substitution | Care and treatment | Retinitis pigmentosa | Physiological aspects | Photoreceptors | Rapamycin | Genetic aspects | Research | Health aspects | Risk factors | Index Medicus
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4. Full Text Treatment With 9-cis β-Carotene–Rich Powder in Patients With Retinitis Pigmentosa : A Randomized Crossover Trial
by Rotenstreich, Ygal and Belkin, Michael and Sadetzki, Siegal and Chetrit, Angela and Ferman-Attar, Gili and Sher, Ifat and Harari, Ayelet and Shaish, Aviv and Harats, Dror
JAMA Ophthalmology, ISSN 2168-6165, 08/2013, Volume 131, Issue 8, pp. 985 - 992
IMPORTANCE Retinitis pigmentosa (RP) is the leading cause of incurable inherited blindness in the developed world, with an estimated prevalence of 1 in 3500... 
LUNG-CANCER | LEBER CONGENITAL AMAUROSIS | RPE65(-/-) MICE | ROD | MOUSE MODEL | RETINAL DISEASES | DOUBLE-BLIND | 9-CIS-BETA-CAROTENE | OPHTHALMOLOGY | ALGA DUNALIELLA-BARDAWIL | 9-CIS-RETINOIC ACID | Visual Fields - physiology | beta Carotene - therapeutic use | Humans | Middle Aged | Male | Young Adult | Light | Adult | Female | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Electroretinography | beta Carotene - blood | Powders | Double-Blind Method | Administration, Oral | Retinitis Pigmentosa - drug therapy | Dark Adaptation - physiology | Treatment Outcome | beta Carotene - administration & dosage | Vitamins - therapeutic use | Cross-Over Studies | Retina - physiology | Chlorophyta | Aged | Vitamins - administration & dosage | Care and treatment | Usage | Retinitis pigmentosa | Analysis | Clinical trials | Placebos | Beta carotene | Index Medicus | Abridged Index Medicus
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5. Full Text Chromatic Pupillometry in Patients with Retinitis Pigmentosa
by Kardon, Randy, MD, PhD|Anderson, Susan C., BA|Damarjian, Tina G., BS|Grace, Elizabeth M., BS|Stone, Edwin, MD, PhD|Kawasaki, Aki, MD and Medicinska fakulteten and Institutionen för klinisk vetenskap and Umeå universitet and Oftalmiatrik
Ophthalmology, ISSN 0161-6420, 2011, Volume 118, Issue 2, pp. 376 - 381
Objective To evaluate the chromatic pupillary response as a means of assessing outer and inner retinal function in patients with retinitis pigmentosa (RP).... 
Ophthalmology | OPHTHALMOLOGY | RESPONSES | PRIMATE RETINA | EXPRESSING GANGLION-CELLS | MELANOPSIN | Electroretinography | Vision Disorders - physiopathology | Visual Fields - physiology | Pupil - physiology | Diagnostic Techniques, Ophthalmological - instrumentation | Reflex, Pupillary - radiation effects | Humans | Light | Female | Male | Photoreceptor Cells, Vertebrate - physiology | Retinitis Pigmentosa - physiopathology | Retinitis pigmentosa | Care and treatment | Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Oftalmologi
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6. Full Text Randomized Trial of Ciliary Neurotrophic Factor Delivered by Encapsulated Cell Intraocular Implants for Retinitis Pigmentosa
by Birch, David G.|Weleber, Richard G.|Duncan, Jacque L.|Jaffe, Glenn J.|Tao, Weng and Ciliary Neurotrophic Factor and Ciliary Neurotrophic Factor Retinitis Pigmentosa Study Groups
American Journal of Ophthalmology, ISSN 0002-9394, 2013, Volume 156, Issue 2, pp. 283 - 292.e1
Purpose To evaluate the safety and effect on visual function of ciliary neurotrophic factor delivered via an intraocular encapsulated cell implant for the... 
Ophthalmology | CNTF | USHER-SYNDROME | DYSTROPHY | ROD | MOUSE | OPHTHALMOLOGY | RECEPTOR | RETINAL-DEGENERATION | GENE-TRANSFER | PHOTORECEPTOR DEGENERATION | VISUAL-FIELD LOSS | Electroretinography | Visual Fields - physiology | Enzyme-Linked Immunosorbent Assay | Tomography, Optical Coherence | Ciliary Neurotrophic Factor - adverse effects | Humans | Middle Aged | Retina - physiopathology | Retinitis Pigmentosa - drug therapy | Drug Implants | Male | Ciliary Neurotrophic Factor - administration & dosage | Drug Delivery Systems | Young Adult | Adolescent | Adult | Female | Aged | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Ciliary neurotrophic factor | Retinitis pigmentosa | Studies | Diabetic retinopathy | Retina | Transplants & implants | Eyes & eyesight | Rodents | Index Medicus | Abridged Index Medicus
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7. Full Text Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa
by Volker Busskamp and Jens Duebel and David Balya and Mathias Fradot and Tim James Viney and Sandra Siegert and Anna C. Groner and Erik Cabuy and Valérie Forster and Mathias Seeliger and Martin Biel and Peter Humphries and Michel Paques and Saddek Mohand-Said and Didier Trono and Karl Deisseroth and José A. Sahel and Serge Picaud and Botond Roska
Science, ISSN 0036-8075, 7/2010, Volume 329, Issue 5990, pp. 413 - 417
Retinitis pigmentosa refers to a diverse group of hereditary diseases that lead to incurable blindness, affecting two million people worldwide. As a common... 
Retinal detachment | Neurons | RESEARCH ARTICLES | Amacrine cells | Retina | Photoreceptors | Retinal cones | Mice | Grants | Electric current | Ganglia | RETINAL DEGENERATION | SEROTYPES | MULTIDISCIPLINARY SCIENCES | GANGLION-CELLS | DIRECTION | HALORHODOPSIN | MOVEMENT | MICE | MODEL | SELECTIVITY | EXPRESSION | Dependovirus - genetics | Genetic Therapy | Promoter Regions, Genetic | Retinal Ganglion Cells - physiology | Tissue Culture Techniques | Humans | Retinal Cone Photoreceptor Cells - physiology | Mice, Knockout | Retina - physiology | Visual Pathways - physiology | Halobacteriaceae - genetics | Animals | Halorhodopsins - metabolism | Transfection | Retinitis Pigmentosa - therapy | Halorhodopsins - genetics | Vision, Ocular | Light | Evoked Potentials, Visual | Genetic Vectors | Retinitis Pigmentosa - physiopathology | Disease Models, Animal | Care and treatment | Properties | Retinitis pigmentosa | Eye diseases | Genetic disorders | Gene therapy | Gene expression | Blindness | Index Medicus | Visual Pathways | Retinal Cone Photoreceptor Cells | Gene Therapy | Dependovirus | Retinal Ganglion Cells | Life Sciences | Retinitis Pigmentosa | Genetics | Halobacteriaceae | Halorhodopsins
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8. Full Text Testing of semichronically implanted retinal prosthesis by suprachoroidal-transretinal stimulation in patients with retinitis pigmentosa
by Fujikado, Takashi and Kamei, Motohiro and Sakaguchi, Hirokazu and Kanda, Hiroyuki and Morimoto, Takeshi and Ikuno, Yasushi and Nishida, Kentaro and Kishima, Haruhiko and Maruo, Tomoyuki and Konoma, Kunihiko and Ozawa, Motoki and Nishida, Kohji
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 06/2011, Volume 52, Issue 7, pp. 4726 - 4733
PURPOSE. To examine the safety and effectiveness of a retinal prosthesis that is implanted semichronically in two patients with advanced retinitis pigmentosa... 
BLIND | ARTIFICIAL VISION | EXTERNAL CONNECTIONS | FEASIBILITY | ELECTRICAL-STIMULATION | OPHTHALMOLOGY | MICROELECTRODE | RABBIT | ELECTRODE ARRAY | SUBRETINAL VISUAL PROSTHESIS | Microelectrodes | Visual Prosthesis | Humans | Choroid | Electrodes, Implanted | Retinitis Pigmentosa - surgery | Visual Acuity | Equipment Design | Recovery of Function | Electric Stimulation - instrumentation | Retina - physiology | Evoked Potentials, Visual | Female | Aged | Retinitis Pigmentosa - physiopathology | Index Medicus
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9. Full Text Evaluation of choroidal thickness in retinitis pigmentosa using enhanced depth imaging optical coherence tomography
by Dhoot, Dilsher S and Huo, Siya and Yuan, Alex and Xu, David and Srivistava, Sunil and Ehlers, Justis P and Traboulsi, Elias and Kaiser, Peter K
British Journal of Ophthalmology, ISSN 0007-1161, 01/2013, Volume 97, Issue 1, pp. 66 - 69
Objective To describe the choroidal characteristics of patients with retinitis pigmentosa (RP) using enhanced depth imaging (EDI) and spectral domain (SD)... 
OPHTHALMOLOGY | CHORIOCAPILLARIS | BLOOD-FLOW | FLUORESCEIN ANGIOGRAPHY | DISEASE | MORPHOLOGICAL-CHANGES | Prospective Studies | Tomography, Optical Coherence | Humans | Middle Aged | Intraocular Pressure - physiology | Male | Case-Control Studies | Young Adult | Retinitis Pigmentosa - complications | Adolescent | Adult | Female | Aged | Choroid - pathology | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Measurement | Usage | Retinitis pigmentosa | Choroid | Diagnosis | Research | Optical tomography | Macular degeneration | Proteins | Studies | Medical imaging | Pathogenesis | Retina | Photoreceptors | Software | Mutation | Age | Index Medicus
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10. Full Text One-year outcome of 49-channel suprachoroidal–transretinal stimulation prosthesis in patients with advanced retinitis pigmentosa
by Fujikado, Takashi and Kamei, Motohiro and Sakaguchi, Hirokazu and Kanda, Hiroyuki and Endo, Takao and Hirota, Masakazu and Morimoto, Takeshi and Nishida, Kentaro and Kishima, Haruhiko and Terasawa, Yasuo and Oosawa, Koji and Ozawa, Motoki and Nishida, Kohji
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 11/2016, Volume 57, Issue 14, pp. 6147 - 6157
PURPOSE. To determine the feasibility of a 49-channel suprachoroidal-transretinal stimulation (STS) retinal prosthesis that was implanted for 1 year. METHODS.... 
Suprachoroidal-transretinal stimulation | Phosphene | Clinical trial | Retinal implant | Retinal prosthesis | Retinitis pigmentosa | retinal prosthesis | clinical trial | retinal implant | ARRAY | TRANSCORNEAL ELECTRICAL-STIMULATION | retinitis pigmentosa | OPHTHALMOLOGY | suprachoroidal-transretinal stimulation | phosphene | Prospective Studies | Follow-Up Studies | Visual Prosthesis | Humans | Middle Aged | Retina - physiopathology | Choroid - physiopathology | Male | Treatment Outcome | Visual Acuity | Feasibility Studies | Pilot Projects | Retinitis Pigmentosa - therapy | Time Factors | Evoked Potentials, Visual | Adult | Female | Aged | Electric Stimulation - methods | Retinitis Pigmentosa - physiopathology | Index Medicus
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11. Full Text Long-term follow-up of patients with retinitis pigmentosa (RP) receiving intraocular ciliary neurotrophic factor implants
by Birch, David G.|Bennett, Lea D.|Duncan, Jacque L.|Weleber, Richard G.|Pennesi, Mark E
American Journal of Ophthalmology, ISSN 0002-9394, 2016, Volume 170, pp. 10 - 14
Purpose To evaluate the long-term efficacy of ciliary neurotrophic factor delivered via an intraocular encapsulated cell implant for the treatment of retinitis... 
Ophthalmology | TRIAL | CNTF | ACTIVATION | DYSTROPHY | MOUSE | ANIMAL-MODELS | OPHTHALMOLOGY | RETINAL-DEGENERATION | GENE-TRANSFER | PHOTORECEPTOR DEGENERATION | DELIVERY | Electroretinography | Visual Fields - physiology | Follow-Up Studies | Tomography, Optical Coherence | Humans | Retina - physiopathology | Retinitis Pigmentosa - drug therapy | Male | Ciliary Neurotrophic Factor - administration & dosage | Drug Delivery Systems | Adult | Female | Aged | Visual Field Tests | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Ciliary neurotrophic factor | Retinitis pigmentosa | Studies | Retina | Photoreceptors | Transplants & implants | Rodents | Pharmaceuticals | Index Medicus | Abridged Index Medicus
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12. Full Text Subretinal Visual Implant Alpha IMS – Clinical trial interim report
by Stingl, Katarina and Bartz-Schmidt, Karl Ulrich and Besch, Dorothea and Chee, Caroline K and Cottriall, Charles L and Gekeler, Florian and Groppe, Markus and Jackson, Timothy L and MacLaren, Robert E and Koitschev, Assen and Kusnyerik, Akos and Neffendorf, James and Nemeth, Janos and Naeem, Mohamed Adheem Naser and Peters, Tobias and Ramsden, James D and Sachs, Helmut and Simpson, Andrew and Singh, Mandeep S and Wilhelm, Barbara and Wong, David and Zrenner, Eberhart
Vision Research, ISSN 0042-6989, 06/2015, Volume 111, Issue Pt B, pp. 149 - 160
A subretinal visual implant (Alpha IMS, Retina Implant AG, Reutlingen, Germany) was implanted in 29 blind participants with outer retinal degeneration in an... 
Neuroprosthetics | Subretinal Implant Alpha IMS | Retinitis pigmentosa | Hereditary retinal diseases | Photoreceptor degeneration | Artificial vision | RETINAL DEGENERATION | SURVIVAL | FEASIBILITY | VISION | FOLLOW-UP | NEUROSCIENCES | PSYCHOLOGY | BLIND PATIENTS | THERAPY | TRANSCORNEAL ELECTRICAL-STIMULATION | OPHTHALMOLOGY | RETINITIS-PIGMENTOSA | PROSTHESIS | Visual Perception - physiology | Blindness - physiopathology | Humans | Middle Aged | Male | Electrodes, Implanted | Retinal Degeneration - physiopathology | Activities of Daily Living | Form Perception - physiology | Blindness - rehabilitation | Adult | Female | Aged | Blindness - etiology | Motion Perception - physiology | Retinitis Pigmentosa - physiopathology | Visual Acuity - physiology | Retinal Degeneration - complications | Clinical trials | Index Medicus
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13. Full Text Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa
by Eysteinsson, Thor and Hardarson, Sveinn H and Bragason, David and Stefánsson, Einar
Acta Ophthalmologica, ISSN 1755-375X, 08/2014, Volume 92, Issue 5, pp. 449 - 453
Purpose: To assess retinal vessel oxygen saturation and retinal vessel diameter in retinitis pigmentosa. Methods: A retinal oximeter (Oxymap ehf., Reykjavik,... 
retinitis pigmentosa | retinal oximetry | oxygen | vessel diameter | DIABETIC-RETINOPATHY | CHORIOCAPILLARIS | CHOROIDAL BLOOD-FLOW | MORPHOMETRIC-ANALYSIS | HISTOPATHOLOGY | OXIMETRY | EPITHELIUM | PLASMA-LEVELS | OPHTHALMOLOGY | PIGMENTATION | ENDOTHELIAL GROWTH-FACTOR | Tomography, Optical Coherence | Humans | Middle Aged | Oximetry | Intraocular Pressure - physiology | Male | Retinal Vein - physiopathology | Oxygen - blood | Young Adult | Retinal Artery - physiopathology | Adult | Female | Blood Pressure - physiology | Retina - pathology | Retinitis Pigmentosa - physiopathology | Retinitis pigmentosa | Index Medicus
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14. Full Text The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss
by da Cruz, Lyndon and Coley, Brian F and Dorn, Jessy and Merlini, Francesco and Filley, Eugene and Christopher, Punita and Chen, Fred K and Wuyyuru, Varalakshmi and Sahel, Jose and Stanga, Paulo and Humayun, Mark and Greenberg, Robert J and Dagnelie, Gislin and Argus II Study Grp and Argus II Study Group and for the Argus II Study Group
British Journal of Ophthalmology, ISSN 0007-1161, 05/2013, Volume 97, Issue 5, pp. 632 - 636
Background Retinal prosthesis systems (RPS) are a novel treatment for profound vision loss in outer retinal dystrophies. Ideal prostheses would offer stable,... 
RESTORE VISION | FEASIBILITY | ELECTRICAL-STIMULATION | IMPLANTATION | VISUAL PERFORMANCE | OPHTHALMOLOGY | RETINAL PROSTHESIS | RETINITIS-PIGMENTOSA | Choroideremia - physiopathology | Vision, Low - physiopathology | Prosthesis Implantation | Prospective Studies | Visual Perception - physiology | Visual Prosthesis | Humans | Middle Aged | Male | Electrodes, Implanted | Choroideremia - surgery | Retinitis Pigmentosa - surgery | Reading | Vision, Low - surgery | </