X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1042) 1042
Publication (146) 146
Book Chapter (14) 14
Newsletter (6) 6
Book Review (4) 4
Conference Proceeding (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (768) 768
animals (461) 461
retinoblastoma protein - metabolism (334) 334
phosphorylation (303) 303
retinoblastoma protein (292) 292
index medicus (276) 276
cell biology (257) 257
oncology (251) 251
mice (247) 247
biochemistry & molecular biology (233) 233
female (207) 207
cell cycle (199) 199
expression (188) 188
male (175) 175
retinoblastoma (161) 161
retinoblastoma - enzymology (157) 157
proteins (151) 151
cancer (140) 140
cell line (138) 138
cells, cultured (138) 138
apoptosis (134) 134
tumor cells, cultured (133) 133
cell line, tumor (129) 129
cyclin-dependent kinases - metabolism (126) 126
signal transduction (98) 98
activation (93) 93
enzyme inhibitors - pharmacology (92) 92
protein-serine-threonine kinases - metabolism (92) 92
rats (92) 92
cyclins - metabolism (91) 91
eye neoplasms - enzymology (91) 91
cell-cycle (89) 89
transfection (89) 89
apoptosis - drug effects (84) 84
cell cycle - drug effects (81) 81
growth (80) 80
molecular sequence data (80) 80
research (80) 80
genetics & heredity (79) 79
enzyme activation (77) 77
blotting, western (75) 75
mutation (75) 75
retinoblastoma protein - genetics (75) 75
cell proliferation (73) 73
gene expression (71) 71
cell cycle proteins (70) 70
gene (70) 70
neoplasms - enzymology (68) 68
phosphorylation - drug effects (68) 68
cyclin-dependent kinase 2 (67) 67
rna, messenger - metabolism (67) 67
cyclin-dependent kinases - antagonists & inhibitors (66) 66
protein (66) 66
transcription factors - metabolism (66) 66
breast neoplasms - enzymology (65) 65
child, preschool (65) 65
cyclin-dependent kinase 4 (65) 65
time factors (65) 65
cell division (64) 64
gene-expression (64) 64
retinoblastoma - pathology (64) 64
tumor suppressor protein p53 - metabolism (64) 64
base sequence (63) 63
cell proliferation - drug effects (63) 63
gene expression regulation, neoplastic (63) 63
research article (62) 62
cyclin d1 - metabolism (61) 61
protein binding (61) 61
child (60) 60
infant (60) 60
proliferation (60) 60
amino acid sequence (58) 58
p53 (58) 58
cdc2-cdc28 kinases (56) 56
differentiation (56) 56
physiological aspects (56) 56
article (55) 55
fibroblasts - enzymology (55) 55
proto-oncogene proteins (55) 55
cells (54) 54
genetic aspects (54) 54
tumors (54) 54
adult (53) 53
cyclin-dependent kinase inhibitor p21 (53) 53
down-regulation (53) 53
cyclin-dependent kinase inhibitor p27 (51) 51
histones - metabolism (51) 51
inhibition (51) 51
retinoblastoma-like protein p130 (51) 51
in-vitro (50) 50
in-vivo (50) 50
retinoblastoma - genetics (50) 50
dose-response relationship, drug (49) 49
e2f transcription factors (49) 49
aqueous humor - enzymology (48) 48
cell division - drug effects (48) 48
middle aged (48) 48
antineoplastic agents - pharmacology (47) 47
breast neoplasms - pathology (47) 47
cell cycle proteins - metabolism (47) 47
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1038) 1038
Chinese (10) 10
Japanese (5) 5
French (3) 3
Polish (2) 2
Russian (2) 2
Italian (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS Pathogens, ISSN 1553-7366, 09/2010, Volume 6, Issue 9, p. e1001092
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2008, Volume 283, Issue 41, pp. 27410 - 27417
Journal Article
by Ma, KL and Liu, J and Wang, CX and Ni, J and Zhang, Y and Wu, Y and Lv, LL and Ruan, XZ and Liu, BC
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 12/2013, Volume 100, Issue 3, pp. 450 - 460
Our previous studies demonstrated that inflammation contributes to atherosclerosis through disruption of the low density lipoprotein receptor (LDLr) pathway.... 
MAMMALIAN TARGET | RAPAMYCIN | COMPLEX | CARDIAC & CARDIOVASCULAR SYSTEMS | CHOLESTEROL | ATHEROSCLEROSIS | Inflammation | LDL receptor pathway | P27(KIP1) | Foam cell formation | PATHWAY | Mammalian target of rapamycin | GROWTH | SMOOTH-MUSCLE-CELLS | EXPRESSION | Inflammation - pathology | Apolipoproteins E - deficiency | TOR Serine-Threonine Kinases - metabolism | Atherosclerosis - genetics | Male | Intracellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | RNA Interference | S Phase | Sterol Regulatory Element Binding Protein 2 - metabolism | Foam Cells - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Atherosclerosis - pathology | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Rats | Receptors, LDL - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Foam Cells - enzymology | Mice, Knockout | Aorta - pathology | Aortic Diseases - genetics | Mice | Inflammation - enzymology | Muscle, Smooth, Vascular - enzymology | Phosphorylation | Endoplasmic Reticulum - metabolism | Phosphoproteins - metabolism | Foam Cells - drug effects | Mechanistic Target of Rapamycin Complex 1 | TOR Serine-Threonine Kinases - antagonists & inhibitors | Atherosclerosis - enzymology | Transfection | Aortic Diseases - enzymology | Membrane Proteins - metabolism | Aorta - enzymology | Aortic Diseases - pathology | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Cells, Cultured | Cholesterol - metabolism | Muscle, Smooth, Vascular - pathology | Animals | Carrier Proteins - metabolism | Apolipoproteins E - genetics | Inflammation - genetics | Golgi Apparatus - metabolism | Protein Kinase Inhibitors - pharmacology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1083 - 1097
Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease; however, it is unclear how or which proteins encoded at this locus... 
ENDOTHELIAL LIPASE | MEDICINE, RESEARCH & EXPERIMENTAL | SEQUENCE VARIANT | CHOLESTEROL EFFLUX | SUSCEPTIBILITY | MUSCLE-CELL APOPTOSIS | CHROMOSOME 9P21 | ABC TRANSPORTERS | CORONARY-HEART-DISEASE | EXPRESSION | MOUSE MODELS | Plaque, Atherosclerotic - genetics | Atherosclerosis - genetics | Coculture Techniques | Humans | Male | Atherosclerosis - enzymology | Plaque, Atherosclerotic - enzymology | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Calreticulin - metabolism | Female | Plaque, Atherosclerotic - pathology | E2F4 Transcription Factor - metabolism | Macrophages - physiology | Atherosclerosis - pathology | Coronary Vessels - pathology | Gene Expression | Myocytes, Smooth Muscle - enzymology | Down-Regulation | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Cells, Cultured | Mice, Knockout | E2F4 Transcription Factor - genetics | Animals | Retinoblastoma Protein - genetics | Carotid Arteries - pathology | Mice | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | Quantitative Trait Loci | Necrosis - enzymology | Phagocytosis | Apoptosis | Physiological aspects | Development and progression | Enzyme inhibitors | Genetic variation | Identification and classification | Atherosclerosis | Studies | Heart attacks | Cardiovascular disease | Software | Genomes | Grants | Kinases | Laboratory animals | Gene expression | Experiments
Journal Article
Cell, ISSN 0092-8674, 03/2007, Volume 128, Issue 6, pp. 1063 - 1076
Methylation of histones has been regarded as a stable modification defining the epigenetic program of the cell, which regulates chromatin structure and... 
DOMAIN-CONTAINING PROTEINS | METHYLATION | CAENORHABDITIS-ELEGANS | METHYLTRANSFERASE | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCAPES X-INACTIVATION | TRITHORAX | RETINOBLASTOMA-BINDING PROTEIN-2 | TRANSCRIPTIONAL REGULATION | CELL BIOLOGY | Caenorhabditis elegans Proteins - chemistry | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phylogeny | Gene Deletion | Tumor Suppressor Proteins - chemistry | Oxidoreductases, N-Demethylating - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Repressor Proteins - metabolism | Amino Acid Sequence | Tumor Suppressor Proteins - metabolism | Repressor Proteins - genetics | Caenorhabditis elegans - embryology | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Histone Demethylases | Lysine | Drosophila melanogaster - enzymology | Schizosaccharomyces - enzymology | Mice | Histones - metabolism | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Embryonic Stem Cells - metabolism | Oxidoreductases, N-Demethylating - genetics | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Tumor Suppressor Proteins - genetics | Carrier Proteins - chemistry | Nuclear Proteins - genetics | Genes, Homeobox | Protein Structure, Tertiary | Repressor Proteins - chemistry | Embryonic Stem Cells - enzymology | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Oxidoreductases, N-Demethylating - chemistry | Proteins - genetics | Carrier Proteins - genetics | Sequence Alignment | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Retinoblastoma-Binding Protein 2 | Proteins - chemistry | Methylation | Jumonji Domain-Containing Histone Demethylases
Journal Article
Cancer Research, ISSN 0008-5472, 09/2006, Volume 66, Issue 18, pp. 9270 - 9280
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2008, Volume 14, Issue 1, pp. 79 - 89
Twist1 and Twist2 are major regulators of embryogenesis. Twist1 has been shown to favor the metastatic dissemination of cancer cells through its ability to... 
CELLBIO | HUMDISEASE | SIGNALING | BREAST-CANCER | TRANSFORMATION | DORSOVENTRAL PATTERN | ONCOGENIC RAS | ONCOLOGY | IN-VIVO | ZYGOTIC GENE | SUPPRESSION | EXPRESSION | TUMORIGENESIS | CELL IMMORTALIZATION | Neoplasms - metabolism | Up-Regulation | Fibroblasts - enzymology | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Transplantation, Heterologous | Cell Transdifferentiation - genetics | Mammary Glands, Human - metabolism | Transfection | Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Mice, Inbred DBA | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Fibroblasts - metabolism | Cell Line | Cellular Senescence - genetics | Neoplasm Invasiveness | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Neoplasms - enzymology | Repressor Proteins - genetics | Epithelial Cells - pathology | Mice, Transgenic | Nuclear Proteins - metabolism | Fibroblasts - pathology | Cell Transformation, Neoplastic - metabolism | Animals | Mice, Nude | Dogs | Epithelial Cells - enzymology | Twist-Related Protein 1 - genetics | Mice | Enzyme Activation | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Twist-Related Protein 1 - metabolism | Tumor proteins | Stem cells | Tumors
Journal Article
Circulation Research, ISSN 0009-7330, 04/2009, Volume 104, Issue 7, pp. 842 - 850
Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) are important pathogenic mechanisms in atherosclerosis and restenosis after... 
Restenosis | NQO1 | AMPK | Vascular smooth muscle cell | β-lapachone | restenosis | ENERGY | CARDIAC & CARDIOVASCULAR SYSTEMS | beta-lapachone | CANCER CELLS | PROTEIN-KINASE ACTIVITY | NEOINTIMA-FORMATION | INHIBITION | PATHWAY | PERIPHERAL VASCULAR DISEASE | vascular smooth muscle cell | CYCLE PROGRESSION | HEMATOLOGY | EXPRESSION | Enzyme Activators - pharmacology | AMP-Activated Protein Kinases - metabolism | Enzyme Activators - toxicity | Phosphorylation | Humans | Hyperplasia | Carotid Stenosis - drug therapy | Myocytes, Smooth Muscle - pathology | Carotid Artery Injuries - drug therapy | Male | Secondary Prevention | NAD(P)H Dehydrogenase (Quinone) - genetics | Dose-Response Relationship, Drug | RNA Interference | Time Factors | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Myocytes, Smooth Muscle - drug effects | Protein-Serine-Threonine Kinases - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Myocytes, Smooth Muscle - enzymology | AMP-Activated Protein Kinases - antagonists & inhibitors | Retinoblastoma Protein - metabolism | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Rats | Naphthoquinones - pharmacology | Tunica Intima - enzymology | Carotid Stenosis - pathology | Naphthoquinones - toxicity | Rats, Sprague-Dawley | NAD(P)H Dehydrogenase (Quinone) - antagonists & inhibitors | Tunica Intima - drug effects | Muscle, Smooth, Vascular - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Carotid Artery Injuries - enzymology | Tunica Intima - pathology | NAD(P)H Dehydrogenase (Quinone) - metabolism | Carotid Stenosis - enzymology | Cell Proliferation - drug effects | Enzyme Activation | HeLa Cells | Cell Cycle - drug effects | Muscle, Smooth, Vascular - enzymology | Acetyl-CoA Carboxylase - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2016, Volume 18, Issue 11, pp. 1519 - 1528
Journal Article
Journal Article
Cardiovascular Research, ISSN 0008-6363, 06/2015, Volume 106, Issue 3, pp. 488 - 497
Aims Being central part of the DNA repair machinery, DNA-dependent protein kinase (DNA-PK) seems to be involved in other signalling processes, as well. NOR1 is... 
Signal transduction | Cardiovascular diseases | Molecular biology | Atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | MACROPHAGES | V(D)J RECOMBINATION | DOUBLE-STRAND BREAKS | NEOINTIMA FORMATION | DAMAGE | REPAIR | PATHWAY | EXPRESSION | DNA-Activated Protein Kinase - antagonists & inhibitors | Cyclin D1 - metabolism | Femoral Artery - pathology | Phosphorylation | Atherosclerosis - genetics | Humans | Myocytes, Smooth Muscle - pathology | Vascular System Injuries - enzymology | Male | Vascular System Injuries - drug therapy | DNA-Binding Proteins - metabolism | Femoral Artery - enzymology | Vascular System Injuries - pathology | Femoral Artery - injuries | Atherosclerosis - enzymology | Ubiquitination | Neointima | Transfection | RNA Interference | Time Factors | Membrane Transport Proteins - genetics | Proteolysis | DNA-Activated Protein Kinase - genetics | DNA-Activated Protein Kinase - metabolism | Membrane Transport Proteins - metabolism | Protein Stability | Vascular Remodeling - drug effects | Myocytes, Smooth Muscle - drug effects | Nuclear Proteins - genetics | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Atherosclerosis - pathology | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | Myocytes, Smooth Muscle - enzymology | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Nuclear Proteins - metabolism | Femoral Artery - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Nuclear Proteins - antagonists & inhibitors | Cell Proliferation - drug effects | Proliferating Cell Nuclear Antigen - metabolism | Muscle, Smooth, Vascular - enzymology
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 12/2017, Volume 232, Issue 12, pp. 3454 - 3467
Lysosomal storage disorders (LDS) comprise a group of rare multisystemic diseases resulting from inherited gene mutations that impair lysosomal homeostasis.... 
senescence | fabry disease | autophagy | lysosomal storage disorders | mesenchymal stem cells | gaucher disease | APOPTOSIS | PHYSIOLOGY | DNA-DAMAGE | CELLULAR SENESCENCE | GAUCHER-DISEASE | P53 | CELL BIOLOGY | REPAIR | THERAPY | STROMAL CELLS | Mesenchymal Stromal Cells - enzymology | alpha-Galactosidase - genetics | Glucosylceramidase - genetics | Bone Marrow Cells - enzymology | Fabry Disease - genetics | Humans | alpha-Galactosidase - metabolism | Fabry Disease - enzymology | Gaucher Disease - pathology | Autophagy | Fabry Disease - pathology | Tumor Suppressor Protein p53 - genetics | S Phase Cell Cycle Checkpoints | Glucosylceramidase - deficiency | Transfection | RNA Interference | Cellular Senescence | Female | Child | Gaucher Disease - enzymology | Stem Cell Niche | Signal Transduction | Cell Separation | Retinoblastoma Protein - metabolism | Amniotic Fluid - cytology | Bone Marrow Cells - pathology | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Gaucher Disease - genetics | Retinoblastoma Protein - genetics | DNA Repair | Mesenchymal Stromal Cells - pathology | Apoptosis | Oxidative stress | Senescence | Disease | Mesenchyme | Disorders | Impairment | Homeostasis | Galactosidase | Staining | Lysosomal storage diseases | Biology | Tissues | DNA repair | a-Galactosidase | Hematopoiesis | Amniotic fluid | Cell cycle | Bone marrow | Ataxia | Physiology | Repair | Damage | Deoxyribonucleic acid--DNA | Gaucher's disease | Enzymes | Organs | Fabry's disease | Hemopoiesis | Storage | Stem cells | Ataxia telangiectasia | Glucosylceramidase | Mutation | In vitro methods and tests | Phagocytosis
Journal Article