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Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3456 - 3463
Multiple myeloma is a monoclonal tumor of plasma cells, and its development is preceded by a premalignant tumor with which it shares genetic abnormalities,... 
LIGHT-CHAIN RATIO | MEDICINE, RESEARCH & EXPERIMENTAL | RAS MUTATIONS | BONE-MARROW | GENE-EXPRESSION | PLASMA-CELL LEUKEMIA | MONOCLONAL GAMMOPATHY | KAPPA-B PATHWAY | FLOW-CYTOMETRY | UNDETERMINED SIGNIFICANCE MGUS | INDEPENDENT RISK-FACTOR | Precancerous Conditions - etiology | Translocation, Genetic | Monoclonal Gammopathy of Undetermined Significance - genetics | Humans | Neoplasm Proteins - physiology | Tumor Microenvironment | Oncogene Proteins, Fusion - physiology | Cyclin D1 - physiology | Neoplastic Stem Cells - pathology | Precancerous Conditions - pathology | Osteoclasts - physiology | Neoplasm Proteins - genetics | Retinoblastoma Protein - physiology | Stem Cell Niche | Genes, Retinoblastoma | Genes, bcl-1 | Monoclonal Gammopathy of Undetermined Significance - etiology | Immunophenotyping | Signal Transduction - genetics | Precancerous Conditions - genetics | Disease Progression | Drug Resistance, Neoplasm - genetics | Multiple Myeloma - etiology | Multiple Myeloma - pathology | Monoclonal Gammopathy of Undetermined Significance - pathology | Cell Transformation, Neoplastic | Models, Biological | Oncogene Proteins, Fusion - genetics | Signal Transduction - physiology | Bone Remodeling | Immunoglobulin Heavy Chains - genetics | Multiple Myeloma - genetics | Immunoglobulins | Gene mutations | Multiple myeloma | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Review Series
Journal Article