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Genomic landscape of retinoblastoma in Rb−/−p130−/− mice resembles human retinoblastoma
Genes chromosomes & cancer, ISSN 1045-2257, 03/2017, Volume 56, Issue 3, pp. 231 - 242
Genetics | Cancer Research | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Retinoblastoma-Like Protein p130 - physiology | Retinoblastoma - genetics | Humans | Mice, Inbred C57BL | Male | DNA Copy Number Variations - genetics | Animals | Female | Biomarkers, Tumor - genetics | Mice | Genome | High-Throughput Nucleotide Sequencing - methods | Retinoblastoma-Like Protein p107 - physiology | Analysis | Genomics | Disease susceptibility | Tumor proteins | Embryonic stem cells | Retinoblastoma | Chromosomes | Tumors | Index Medicus
Journal Article
The Journal of cell biology, ISSN 0021-9525, 08/2011, Volume 194, Issue 3, pp. 407 - 423
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Chromatin | Chromosomal Proteins, Non-Histone - metabolism | Myocytes, Cardiac - cytology | Retinoblastoma Protein - metabolism | Cell Cycle Proteins - metabolism | Genes, Retinoblastoma - genetics | E2F Transcription Factors - metabolism | Mice, Knockout | Heterochromatin | Patch-Clamp Techniques | Animals | Cell Cycle | RNA Interference | Retinoblastoma-Like Protein p130 - metabolism | Myocytes, Cardiac - physiology | Retinoblastoma Protein - genetics | Polymerase Chain Reaction | Cell Cycle Proteins - genetics | Mice | RNA, Small Interfering | E2F Transcription Factors - genetics | Jumonji Domain-Containing Histone Demethylases - metabolism | Retinoblastoma-Like Protein p130 - genetics | Genetic aspects | Genetic engineering | DNA binding proteins | Cell cycle | Genotype & phenotype | Cardiomyocytes | Rodents | Genes | Index Medicus | Birth
Journal Article
Oncogene, ISSN 0950-9232, 10/2009, Volume 28, Issue 39, pp. 3456 - 3467
Senescence | DNA-damage | Rb2/p130 | P53 | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | G1 Phase | Retinoblastoma-Like Protein p130 - metabolism | Signal Transduction | Cellular Senescence | DNA Repair | Humans | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Cell Line, Tumor | DNA Damage | p21-Activated Kinases - metabolism | Fibroblasts - metabolism | Cellular proteins | DNA damage | Physiological aspects | Aging | Genetic aspects | Research | Cells | Proteins | Genetics | Cell cycle | Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 05/2010, Volume 70, Issue 10, pp. 3877 - 3883
Life Sciences & Biomedicine | Oncology | Science & Technology | Pharmacology. Drug treatments | Tumors of the respiratory system and mediastinum | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Pneumology | Lung Neoplasms - genetics | Prognosis | Retinoblastoma-Like Protein p130 - physiology | Oligonucleotide Array Sequence Analysis | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Gene Expression Profiling | Small Cell Lung Carcinoma - genetics | Mice, Knockout | Small Cell Lung Carcinoma - metabolism | Tumor Suppressor Protein p53 - physiology | Small Cell Lung Carcinoma - pathology | Animals | Mice, Nude | Biomarkers, Tumor - metabolism | Integrases - metabolism | Biomarkers, Tumor - genetics | Mice | Retinoblastoma Protein - physiology | Index Medicus | mouse model | p130 | small cell lung carcinoma | p53
Journal Article
Molecular cell, ISSN 1097-2765, 2007, Volume 26, Issue 4, pp. 539 - 551
CELLCYCLE | DNA | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Gene Expression Regulation, Neoplastic | Crk-Associated Substrate Protein - metabolism | Drosophila melanogaster - genetics | Kv Channel-Interacting Proteins - genetics | Protein Subunits - metabolism | Drosophila melanogaster - metabolism | Neoplasms - genetics | Retinoblastoma-Like Protein p130 - metabolism | Gene Deletion | Conserved Sequence | E2F4 Transcription Factor - metabolism | Protein Subunits - genetics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Gene Expression Regulation | Cellular Senescence - physiology | Repressor Proteins - genetics | Proteome | Crk-Associated Substrate Protein - genetics | E2F4 Transcription Factor - genetics | Animals | Retinoblastoma Protein - genetics | Cell Cycle - physiology | Mutation | Retinoblastoma-Like Protein p130 - genetics | Evolution, Molecular | Suppression, Genetic | Proteins | Index Medicus
Journal Article
Nucleic acids research, ISSN 0305-1048, 01/2011, Volume 39, Issue 2, pp. 440 - 453
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Promoter Regions, Genetic | Protein Biosynthesis | Introns | Down-Regulation | Humans | Transcriptional Activation | Cell Cycle Proteins - metabolism | Computational Biology | Cyclin-Dependent Kinase 6 - genetics | Gene Expression Regulation | Tumor Suppressor Protein p53 - metabolism | MicroRNAs - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Cyclin-Dependent Kinase 6 - metabolism | Genetic Loci | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Cell Cycle | Retinoblastoma-Like Protein p130 - metabolism | Cell Cycle Proteins - genetics | MicroRNAs - genetics | DNA Damage | Retinoblastoma-Like Protein p130 - genetics | Index Medicus | Gene Regulation, Chromatin and Epigenetics
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 07/2009, Volume 284, Issue 29, pp. 19265 - 19271
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Fluorescence Recovery After Photobleaching | Humans | Immunoblotting | Retinoblastoma-Like Protein p107 - genetics | Green Fluorescent Proteins - genetics | Cyclin A - genetics | Promoter Regions, Genetic - genetics | Recombinant Fusion Proteins - metabolism | E2F Transcription Factors - metabolism | Transfection | Chromatin Immunoprecipitation | Retinoblastoma-Like Protein p130 - metabolism | Bromodeoxyuridine - metabolism | Green Fluorescent Proteins - metabolism | Gene Expression | Retinoblastoma-Like Protein p107 - metabolism | Cyclin A - metabolism | Retinoblastoma Protein - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Microscopy, Confocal | Retinoblastoma Protein - genetics | Cell Line, Tumor | Protein Binding | Recombinant Fusion Proteins - genetics | Retinoblastoma-Like Protein p130 - genetics | Index Medicus | Transcription, Chromatin, and Epigenetics
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 41, pp. 15815 - 15826
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Up-Regulation | Molecular Chaperones | Cell Proliferation | Down-Regulation | Humans | Gene Silencing | Tumor Suppressor Protein p53 - metabolism | Cell Cycle | Retinoblastoma-Like Protein p130 - metabolism | Cellular Senescence | Heat-Shock Proteins | Oxygen - chemistry | Cell Line, Tumor | G2 Phase | HSP27 Heat-Shock Proteins - metabolism | Lung - metabolism | E2F4 Transcription Factor - metabolism | Fibroblasts - metabolism | RNA, Small Interfering - metabolism | Index Medicus | E2F transcription factor | cellular senescence | cell proliferation | cell cycle | cyclin B1 | HSPB1 | transcription repressor | small heat shock protein (sHsp) | cyclin A2 | Cell Biology | cyclin B2
Journal Article
Journal of cellular physiology, ISSN 0021-9541, 04/2011, Volume 226, Issue 4, pp. 1027 - 1034
Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amino Acid Sequence | Catalytic Domain | Humans | Ovarian Neoplasms - pathology | Molecular Sequence Data | Protein Transport - drug effects | Retinoblastoma-Like Protein p130 - chemistry | Ovarian Neoplasms - enzymology | Cell Nucleus - metabolism | Karyopherins - metabolism | Peptides - metabolism | Nuclear Localization Signals - chemistry | Retinoblastoma-Like Protein p130 - metabolism | Models, Biological | Protein Binding - drug effects | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Female | Phosphorylation - drug effects | Cell Nucleus - drug effects | Tretinoin - pharmacology | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2017, Volume 292, Issue 16, pp. 6583 - 6599
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cytomegalovirus - genetics | Promoter Regions, Genetic | Phosphorylation | Retinoblastoma-Like Protein p107 - metabolism | Cytomegalovirus - metabolism | Humans | Gene Expression Regulation, Neoplastic | Phosphotransferases (Alcohol Group Acceptor) - genetics | Cytomegalovirus Infections - metabolism | Gene Expression Profiling | E2F1 Transcription Factor - metabolism | Amino Acid Motifs | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Immediate-Early Proteins - metabolism | Retinoblastoma-Like Protein p130 - metabolism | Alleles | HEK293 Cells | Mutation | Fibroblasts - metabolism | Index Medicus | HCMV | herpesvirus | cyclin-dependent kinase (CDK) | cancer | oncogene | phosphorylation | tumor suppressor gene | Cell Biology
Journal Article