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Journal Article
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 12/2011, Volume 1811, Issue 12, pp. 1105 - 1114
Apo-10'-lycopenoic acid (apo-10-lycac), a metabolite of lycopene, has been shown to possess potent biological activities, notably via the retinoic acid... 
RAR | Inflammation | Adipose tissue | Adipocytes | Lycopene | apo-10'-lycopenoic acid | 3T3-L1 ADIPOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | NECROSIS-FACTOR-ALPHA | IDENTIFICATION | VITAMIN-A | CELL BIOLOGY | IN-VITRO | INTESTINAL-CELLS | BIOPHYSICS | apo-10 '-lycopenoic acid | INSULIN-RESISTANCE | GENE-EXPRESSION | DIETARY | Obesity - drug therapy | Oligonucleotide Array Sequence Analysis | Transcriptional Activation - drug effects | Adipose Tissue - cytology | RNA, Messenger - analysis | Adipocytes - cytology | Male | Gene Expression Profiling | Adipocytes - drug effects | Obesity - genetics | Carotenoids - pharmacology | Receptors, Retinoic Acid - genetics | Adipose Tissue - metabolism | RNA, Messenger - biosynthesis | Inflammation - metabolism | Inflammation - drug therapy | Interleukin-1beta - biosynthesis | Real-Time Polymerase Chain Reaction | Genes, Reporter | Tretinoin - pharmacology | Tissue Culture Techniques | Mice, Inbred C57BL | Interleukin-1beta - immunology | Fatty Acids, Unsaturated - pharmacology | Receptors, Retinoic Acid - metabolism | Inflammation - immunology | 3T3-L1 Cells | Obesity - metabolism | Animals | Adipocytes - metabolism | Interleukin-6 - immunology | Inflammation - genetics | Interleukin-6 - biosynthesis | Mice | Adipose Tissue - drug effects | Adipose tissues | Metabolites | Analysis | Genes | Physiological aspects | Gene expression | Life Sciences
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2013, Volume 369, Issue 2, pp. 111 - 121
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 2006, Volume 70, Issue 3, pp. 909 - 924
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e43692 - e43692
Background: Valproic acid (VPA) is an antiepileptic and anti-migraine prophylactic drug. VPA exhibits two severe side effects, namely acute liver toxicity and... 
CARNITINE | METABOLITES | MECHANISM | RAT | MULTIDISCIPLINARY SCIENCES | ANTICONVULSANT | RETINOL-BINDING-PROTEIN | HISTONE-DEACETYLASE INHIBITORS | RECEPTORS | EXPRESSION | DEHYDROGENASE | Teratogens - toxicity | Embryonic Development - genetics | Vitamin A - toxicity | Histone Deacetylases - metabolism | Hypervitaminosis A - genetics | Hypervitaminosis A - metabolism | Chick Embryo | Valproic Acid - pharmacology | Valproic Acid - toxicity | Hydrogen Peroxide - metabolism | Vitamin A - metabolism | Abnormalities, Drug-Induced | Phenotype | Animals | Proteomics | Homeostasis - drug effects | Kinetics | Retinol-Binding Proteins, Plasma - metabolism | Embryonic Development - drug effects | Retinol-Binding Proteins, Plasma - genetics | Homeostasis - genetics | Superoxide Dismutase - metabolism | Teratogens - metabolism | Hypervitaminosis | Divalproex | Complications and side effects | Development and progression | Dosage and administration | Research | Valproic acid | Risk factors | Cytochrome | Oxidative stress | Histone deacetylase | Biotechnology | Headache | Cytochrome b5 | Dehydrogenases | Toxicity | Liver | Urology | Proteins | Teratogenesis | Vitamin A | NADH | Metabolites | Rodents | Drug dosages | Migraine | Glycerol | Vitamin deficiency | Metabolism | Gene expression | Apolipoproteins | Embryos | Medicine | Side effects | Acids | Carbonic anhydrase | Teratogenicity | Nicotinamide adenine dinucleotide | NADH-cytochrome b5 reductase | Potassium | Retinoic acid | Reductase | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 50, pp. 42195 - 42205
Retinoic acid (RA) regulates gene transcription by activating the nuclear receptors retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor... 
LIM PROTEIN | STEM-CELLS | EMBRYONAL CARCINOMA-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | F9 TERATOCARCINOMA CELLS | REV-ERB-ALPHA | NEURONAL DIFFERENTIATION | KERATINOCYTES | EXPRESSION | BINDING PROTEIN-II | Sirtuin 1 - metabolism | Neurons - cytology | Fatty Acid-Binding Proteins - metabolism | LIM Domain Proteins - metabolism | Neoplasm Proteins - metabolism | Neural Stem Cells - cytology | Sirtuin 1 - genetics | Receptors, Retinoic Acid - genetics | Mice, Mutant Strains | Antineoplastic Agents - pharmacology | Neurogenesis - drug effects | Neurons - metabolism | Neoplasm Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Tretinoin - pharmacology | Cell Line | PPAR-beta - metabolism | Protein-Serine-Threonine Kinases - genetics | Receptors, Retinoic Acid - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Hippocampus - cytology | PPAR-beta - genetics | Fatty Acid-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Animals | Signal Transduction - drug effects | Neurogenesis - physiology | LIM Domain Proteins - genetics | Signal Transduction - physiology | Mice | Neural Stem Cells - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Transcription Regulation | Retinoid-binding Protein | Neurodifferentiation | Nuclear Receptors | Retinoid | Cell Biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/1999, Volume 96, Issue 26, pp. 14807 - 14812
Analyzing the pathways by which retinoic acid (RA) induces promyelocytic leukemia/retinoic acid receptor α (PML/RARα) catabolism in acute promyelocytic... 
COS cells | Biological Sciences | Receptors | DNA | Agonists | Ligands | Catabolism | Retinoids | Nuclear receptors | Down regulation | CHO cells | ONCOPROTEIN | NUCLEAR-BODIES | GROWTH-SUPPRESSOR | NB4 CELLS | MULTIDISCIPLINARY SCIENCES | DIFFERENTIATION | EXPRESSION | PLZF | HISTONE DEACETYLASE | PML | ACUTE PROMYELOCYTIC LEUKEMIA | retinoic acid receptors
Journal Article