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Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2001, Volume 193, Issue 7, pp. 827 - 838
Journal Article
Brain, ISSN 0006-8950, 12/2015, Volume 138, Issue 12, pp. 3581 - 3597
Journal Article
Nature Communications, ISSN 2041-1723, 09/2015, Volume 6, Issue 1, pp. 8089 - 8089
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2000, Volume 275, Issue 36, pp. 28240 - 28245
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0145467 - e0145467
Alzheimer's disease (AD) is the major cause of dementia worldwide. The pharmacological activation of nuclear receptors (Liver X receptors: LXRs or Retinoid X... 
WILD-TYPE | AMYLOID BETA-PEPTIDE | ADULT NEUROGENESIS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | SUBVENTRICULAR ZONE | TRANSGENIC MODEL | DENTATE GYRUS | HIPPOCAMPAL NEUROGENESIS | APOLIPOPROTEIN-E | Benzoates - therapeutic use | Cerebral Cortex - pathology | tau Proteins - metabolism | Cognition Disorders - metabolism | Male | Hippocampus - drug effects | Orphan Nuclear Receptors - metabolism | Apolipoproteins E - metabolism | Excitatory Postsynaptic Potentials - drug effects | ATP Binding Cassette Transporter 1 - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Gliosis - pathology | Dentate Gyrus - drug effects | Long-Term Potentiation - drug effects | Liver X Receptors | Amyloid beta-Peptides - metabolism | Female | Cerebral Cortex - drug effects | Biomarkers - metabolism | Alzheimer Disease - physiopathology | Cognition Disorders - physiopathology | Dentate Gyrus - metabolism | Orphan Nuclear Receptors - agonists | Neural Stem Cells - drug effects | Alzheimer Disease - drug therapy | Mice, Transgenic | Nuclear Proteins - metabolism | Hippocampus - pathology | Cognition Disorders - drug therapy | Gliosis - complications | Nerve Tissue Proteins - metabolism | Nestin - metabolism | Up-Regulation - drug effects | Hippocampus - metabolism | Cognition Disorders - complications | Animals | Alzheimer Disease - metabolism | Fluorescent Antibody Technique | Benzoates - pharmacology | Protein Biosynthesis - drug effects | Cell Proliferation - drug effects | Benzylamines - pharmacology | Benzylamines - therapeutic use | Dentate Gyrus - pathology | Neural Stem Cells - metabolism | Brain | Advertising executives | Cognition | Apolipoproteins | Alzheimer's disease | Liver | Amyloidogenesis | Peptides | Cognitive ability | Proteins | Receptors | Neurodegeneration | Physiology | Chemical synthesis | Neurodegenerative diseases | Cortex | Protein biosynthesis | Behavioral sciences | Metabolism | Retinoid X receptors | Nuclear receptors | Dentate gyrus | Gliosis | Molecular modelling | Tau protein | Protein synthesis | Stem cells | Ligands | ATP-binding protein | Hippocampus | Animal models | Cerebral cortex | Lipids | Kinases | Neurogenesis | ABCA1 protein | Reduction | Metabolites | Apolipoprotein E | Rodents | Dementia disorders | Liver X receptors | Neurons | Pharmacology | Cholesterol | Cortex (entorhinal) | Plasticity (synaptic) | Presenilin 1 | Laboratory animals | Alzheimers disease | Animal cognition | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2014, Volume 74, Issue 16, pp. 4364 - 4377
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 44, pp. 30538 - 30555
Previous data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and insoluble amyloid-beta (A beta) in Alzheimer disease... 
BEXAROTENE THERAPY | ABCA1 | ALZHEIMERS-DISEASE | DEPOSITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | A-BETA | TRANSGENIC MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | BRAIN | APOLIPOPROTEIN-E | Disks Large Homolog 4 Protein | Liver - pathology | Nicotinic Acids - pharmacokinetics | Humans | Male | Tetrahydronaphthalenes - adverse effects | ATP Binding Cassette Transporter 1 - metabolism | Liver - drug effects | Tetrahydronaphthalenes - administration & dosage | Amyloid beta-Peptides - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Membrane Proteins - metabolism | Nicotinic Acids - administration & dosage | Drug Evaluation, Preclinical | Nicotinic Acids - adverse effects | Retinoid X Receptors - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Bexarotene | Peptide Fragments - metabolism | Administration, Oral | Mice, Inbred C57BL | Solubility | Alzheimer Disease - drug therapy | Tetrahydronaphthalenes - pharmacokinetics | Genotype | Mice, Transgenic | Organ Size - drug effects | Animals | Retinoid X Receptors - agonists | Apolipoproteins E - genetics | Guanylate Kinases - metabolism | Index Medicus | Molecular Bases of Disease | Oligomeric Aβ | Alzheimer Disease | Drug Delivery | Aβ Complex | Apolipoprotein E (ApoE) | Amyloid-β (AB) | RXR Agonists | Hepatomegaly | ABCG1 Lipid Transporters | Drug Action | ApoE
Journal Article